Published in Annu Rev Cell Dev Biol on August 06, 2012
Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal. Nat Biotechnol (2014) 1.77
Organization and execution of the epithelial polarity programme. Nat Rev Mol Cell Biol (2014) 1.67
Inhibition of JAK-STAT signaling stimulates adult satellite cell function. Nat Med (2014) 1.51
Role of membrane traffic in the generation of epithelial cell asymmetry. Nat Cell Biol (2012) 1.33
The Hippo-YAP signaling pathway and contact inhibition of growth. J Cell Sci (2014) 1.29
Cell polarity as a regulator of cancer cell behavior plasticity. Annu Rev Cell Dev Biol (2012) 1.15
The Hippo pathway polarizes the actin cytoskeleton during collective migration of Drosophila border cells. J Cell Biol (2013) 1.10
Sticking together the Crumbs - an unexpected function for an old friend. Nat Rev Mol Cell Biol (2013) 1.07
Crumbs3 is essential for proper epithelial development and viability. Mol Cell Biol (2013) 1.01
The microcephaly protein Asp regulates neuroepithelium morphogenesis by controlling the spatial distribution of myosin II. Nat Cell Biol (2013) 1.01
Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex. Proc Natl Acad Sci U S A (2014) 0.95
Oncogenic suppression of apoptosis uncovers a Rac1/JNK proliferation pathway activated by loss of Par3. Oncogene (2014) 0.94
Guidance of subcellular tubulogenesis by actin under the control of a synaptotagmin-like protein and Moesin. Nat Commun (2014) 0.93
"You Shall Not Pass"-tight junctions of the blood brain barrier. Front Neurosci (2014) 0.92
Aurora kinases phosphorylate Lgl to induce mitotic spindle orientation in Drosophila epithelia. Curr Biol (2014) 0.90
Apical targeting of the formin Diaphanous in Drosophila tubular epithelia. Elife (2013) 0.90
Differential regulation of the Hippo pathway by adherens junctions and apical-basal cell polarity modules. Proc Natl Acad Sci U S A (2015) 0.89
The transcriptional response to tumorigenic polarity loss in Drosophila. Elife (2015) 0.89
Disruption of prostate epithelial differentiation pathways and prostate cancer development. Front Oncol (2013) 0.89
Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation. J Cell Biol (2013) 0.88
The Mammalian Blood-Testis Barrier: Its Biology and Regulation. Endocr Rev (2015) 0.88
Structural basis for the phosphorylation-regulated interaction between the cytoplasmic tail of cell polarity protein crumbs and the actin-binding protein moesin. J Biol Chem (2015) 0.86
Regulation of actin dynamics and protein trafficking during spermatogenesis--insights into a complex process. Crit Rev Biochem Mol Biol (2013) 0.86
Cell polarity in morphogenesis and metastasis. Philos Trans R Soc Lond B Biol Sci (2013) 0.86
Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells. Sci Rep (2016) 0.84
Radial intercalation is regulated by the Par complex and the microtubule-stabilizing protein CLAMP/Spef1. J Cell Biol (2014) 0.82
Shot and Patronin polarise microtubules to direct membrane traffic and biogenesis of microvilli in epithelia. J Cell Sci (2016) 0.82
Par-complex aPKC and Par3 cross-talk with innate immunity NF-κB pathway in epithelial cells. Biol Open (2013) 0.81
Crumbs is an essential regulator of cytoskeletal dynamics and cell-cell adhesion during dorsal closure in Drosophila. Elife (2015) 0.81
Cdc42 and formin activity control non-muscle myosin dynamics during Drosophila heart morphogenesis. J Cell Biol (2014) 0.81
Crumbs promotes expanded recognition and degradation by the SCF(Slimb/β-TrCP) ubiquitin ligase. Proc Natl Acad Sci U S A (2014) 0.81
Morphogenesis of the mouse neural plate depends on distinct roles of cofilin 1 in apical and basal epithelial domains. Development (2015) 0.80
Cadherin 99C regulates apical expansion and cell rearrangement during epithelial tube elongation. Development (2014) 0.80
Establishment of Par-Polarized Cortical Domains via Phosphoregulated Membrane Motifs. Dev Cell (2015) 0.80
Development and dynamics of cell polarity at a glance. J Cell Sci (2017) 0.79
Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Nat Cell Biol (2015) 0.79
JAK/STAT and Hox Dynamic Interactions in an Organogenetic Gene Cascade. PLoS Genet (2015) 0.79
Asymmetric cell division in the Drosophila bristle lineage: from the polarization of sensory organ precursor cells to Notch-mediated binary fate decision. Wiley Interdiscip Rev Dev Biol (2015) 0.79
Apical localisation of crumbs in the boundary cells of the Drosophila hindgut is independent of its canonical interaction partner stardust. PLoS One (2014) 0.79
aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization. Dev Cell (2016) 0.78
The retromer complex in development and disease. Development (2015) 0.78
Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove. Acta Crystallogr D Biol Crystallogr (2015) 0.78
The F-box protein Slmb restricts the activity of aPKC to polarize epithelial cells. Development (2014) 0.78
The Ski2-family helicase Obelus regulates Crumbs alternative splicing and cell polarity. J Cell Biol (2015) 0.78
PTEN phosphatase-independent maintenance of glandular morphology in a predictive colorectal cancer model system. Neoplasia (2013) 0.78
Adriamycin-Induced Models of VACTERL Association. Mol Syndromol (2013) 0.78
Mouse Crumbs3 sustains epithelial tissue morphogenesis in vivo. Sci Rep (2015) 0.77
Expression of polarity genes in human cancer. Cancer Inform (2015) 0.77
In vivo functional analysis of the human NF2 tumor suppressor gene in Drosophila. PLoS One (2014) 0.77
Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation. Nat Cell Biol (2016) 0.77
Bazooka/PAR3 is dispensable for polarity in Drosophila follicular epithelial cells. Biol Open (2015) 0.77
The transmembrane protein Crumbs displays complex dynamics during follicular morphogenesis and is regulated competitively by Moesin and aPKC. Development (2015) 0.76
The apical complex protein Pals1 is required to maintain cerebellar progenitor cells in a proliferative state. Development (2015) 0.76
Netrins and Frazzled/DCC promote the migration and mesenchymal to epithelial transition of Drosophila midgut cells. Biol Open (2015) 0.76
Mechanisms of polarity protein expression control. Curr Opin Cell Biol (2016) 0.76
Vesicular sorting controls the polarity of expanding membranes in the C. elegans intestine. Worm (2013) 0.76
Localization and Function of Pals1-associated Tight Junction Protein in Drosophila Is Regulated by Two Distinct Apical Complexes. J Biol Chem (2015) 0.76
A combined binary interaction and phenotypic map of C. elegans cell polarity proteins. Nat Cell Biol (2016) 0.76
Loss of Cell Adhesion Increases Tumorigenic Potential of Polarity Deficient Scribble Mutant Cells. PLoS One (2016) 0.75
Changes in organelle position and epithelial architecture associated with loss of CrebA. Biol Open (2015) 0.75
Connections between cadherin-catenin proteins, spindle misorientation, and cancer. Tissue Barriers (2015) 0.75
Crumbs and Xpd in mitosis. Oncoscience (2015) 0.75
Apicobasal polarity of brain endothelial cells. J Cereb Blood Flow Metab (2015) 0.75
Dynamic analysis of the mesenchymal-epithelial transition of blood-brain barrier forming glia in Drosophila. Biol Open (2017) 0.75
Physiological extracellular electrical signals guide and orient the polarity of gut epithelial cells. Tissue Barriers (2015) 0.75
Molecular Control of Atypical Protein Kinase C: Tipping the Balance between Self-Renewal and Differentiation. J Mol Biol (2016) 0.75
Disruption of the Cdc42/Par6/aPKC or Dlg/Scrib/Lgl Polarity Complex Promotes Epithelial Proliferation via Overlapping Mechanisms. PLoS One (2016) 0.75
The Crumbs_C isoform of Drosophila shows tissue- and stage-specific expression and prevents light-dependent retinal degeneration. Biol Open (2017) 0.75
Par system components are asymmetrically localized in ectodermal epithelia, but not during early development in the sea anemone Nematostella vectensis. Evodevo (2015) 0.75
Dlg5 maintains apical polarity by promoting membrane localization of Crumbs during Drosophila oogenesis. Sci Rep (2016) 0.75
The Drosophila ZO-1 protein Polychaetoid suppresses Deltex-regulated Notch activity to modulate germline stem cell niche formation. Open Biol (2017) 0.75
Crumbs affects protein dynamics in anterior regions of the developing Drosophila embryo. PLoS One (2013) 0.75
Peptide binding properties of the three PDZ domains of Bazooka (Drosophila Par-3). PLoS One (2014) 0.75
Getting to the core of cadherin complex function in Caenorhabditis elegans. F1000Res (2015) 0.75
A nanobody-based toolset to investigate the role of protein localization and dispersal in Drosophila. Elife (2017) 0.75
Fluorescently tagged Lin7c is a dynamic marker for polarity maturation in the zebrafish retinal epithelium. Biol Open (2013) 0.75
The C. elegans Crumbs family contains a CRB3 homolog and is not essential for viability. Biol Open (2015) 0.75
The PCP pathway regulates Baz planar distribution in epithelial cells. Sci Rep (2016) 0.75
Domain-specific functions of Stardust in Drosophila embryonic development. R Soc Open Sci (2016) 0.75
Kibra and Merlin Activate the Hippo Pathway Spatially Distinct from and Independent of Expanded. Dev Cell (2017) 0.75
Regulation of Catalytic and Non-catalytic Functions of the Drosophila Ste20 Kinase Slik by Activation Segment Phosphorylation. J Biol Chem (2015) 0.75
Protein clustering for cell polarity: Par-3 as a paradigm. F1000Res (2017) 0.75
EPEC effector EspF promotes Crumbs3 endocytosis and disrupts epithelial cell polarity. Cell Microbiol (2017) 0.75
Characterization of the cell polarity gene crumbs during the early development and maintenance of the squid-vibrio light organ symbiosis. Dev Genes Evol (2017) 0.75
A Kinome RNAi Screen in Drosophila Identifies Novel Genes Interacting with Lgl, aPKC, and Crb Cell Polarity Genes in Epithelial Tissues. G3 (Bethesda) (2017) 0.75
Distinct functions of Crumbs regulating slit diaphragms and endocytosis in Drosophila nephrocytes. Cell Mol Life Sci (2017) 0.75
Polarity protein Par3/Bazooka follows myosin-dependent junction repositioning. Dev Biol (2017) 0.75
Neutral Competition for Drosophila Follicle and Cyst Stem Cell Niches Requires Vesicle Trafficking Genes. Genetics (2017) 0.75