Kazuhiro Tanaka

Author PubWeight™ 79.77‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation. Genes Dev 2003 3.95
2 mTOR complex 2 controls glycolytic metabolism in glioblastoma through FoxO acetylation and upregulation of c-Myc. Cell Metab 2013 1.86
3 An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway. Cancer Discov 2011 1.77
4 Frequent alteration of p16(INK4a)/p14(ARF) and p53 pathways in the round cell component of myxoid/round cell liposarcoma: p53 gene alterations and reduced p14(ARF) expression both correlate with poor prognosis. J Pathol 2005 1.60
5 The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation. Proc Natl Acad Sci U S A 2010 1.45
6 CXCR4 and VEGF expression in the primary site and the metastatic site of human osteosarcoma: analysis within a group of patients, all of whom developed lung metastasis. Mod Pathol 2006 1.42
7 Suberoylanilide hydroxamic acid (SAHA) induces apoptosis or autophagy-associated cell death in chondrosarcoma cell lines. Anticancer Res 2008 1.38
8 Chondromyxoid fibroma of the clavicle. J Orthop Sci 2006 1.38
9 Primitive neuroectodermal tumor and extraskeletal Ewing sarcoma arising primarily around the spinal column: report of four cases and a review of the literature. Spine (Phila Pa 1976) 2003 1.35
10 Identification of p21WAF1/CIP1 as a direct target of EWS-Fli1 oncogenic fusion protein. J Biol Chem 2003 1.34
11 Possible involvement of the vascular endothelial growth factor-Flt-1-focal adhesion kinase pathway in chemotaxis and the cell proliferation of osteoclast precursor cells in arthritic joints. J Immunol 2002 1.29
12 EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer. Cell Metab 2013 1.23
13 Multiinstitutional phase II study of neoadjuvant chemotherapy for osteosarcoma (NECO study) in Japan: NECO-93J and NECO-95J. J Orthop Sci 2009 1.22
14 mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma. Sci Transl Med 2012 1.21
15 Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240. Proc Natl Acad Sci U S A 2012 1.15
16 Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment. J Clin Invest 2015 1.15
17 Prognostic implication of SYT-SSX fusion type in synovial sarcoma: a multi-institutional retrospective analysis in Japan. Oncol Rep 2008 1.09
18 Metastasis to the gluteus maximus muscle from renal cell carcinoma with special emphasis on MRI features. World J Surg Oncol 2007 1.08
19 De-repression of PDGFRβ transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients. Cancer Discov 2013 1.07
20 Antitumor effects of histone deacetylase inhibitor on Ewing's family tumors. Int J Cancer 2005 1.04
21 Long-term survival after surgical resection of primary spinal malignant melanoma. Neurol Med Chir (Tokyo) 2009 1.04
22 The effects of histone deacetylase inhibitors on the induction of differentiation in chondrosarcoma cells. Clin Cancer Res 2007 1.00
23 MicroRNA-183 upregulates HIF-1α by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells. J Neurooncol 2012 1.00
24 Clinical outcome of patients with Ewing sarcoma family of tumors of bone in Japan: the Japanese Musculoskeletal Oncology Group cooperative study. Cancer 2007 1.00
25 APC mutations in synovial sarcoma. J Pathol 2002 1.00
26 Depression-like behavior in the forced swimming test in PACAP-deficient mice: amelioration by the atypical antipsychotic risperidone. J Neurochem 2009 1.00
27 GC/MS-based metabolomic analysis of cerebrospinal fluid (CSF) from glioma patients. J Neurooncol 2013 0.99
28 Synthetic Smac peptide enhances the effect of etoposide-induced apoptosis in human glioblastoma cell lines. J Neurooncol 2006 0.96
29 The possible role of EWS-Fli1 in evasion of senescence in Ewing family tumors. Cancer Res 2006 0.95
30 The mechanism of cross-resistance to proteasome inhibitor bortezomib and overcoming resistance in Ewing's family tumor cells. Int J Oncol 2007 0.94
31 Changes in light-induced phase shift of circadian rhythm in mice lacking PACAP. Biochem Biophys Res Commun 2003 0.94
32 E-cadherin mutation and Snail overexpression as alternative mechanisms of E-cadherin inactivation in synovial sarcoma. Oncogene 2004 0.93
33 Possible association between higher beta-catenin mRNA expression and mutated beta-catenin in sporadic desmoid tumors: real-time semiquantitative assay by TaqMan polymerase chain reaction. Lab Invest 2002 0.93
34 The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas. Clin Cancer Res 2013 0.91
35 Focal adhesion kinase is activated in invading fibrosarcoma cells and regulates metastasis. Clin Exp Metastasis 2005 0.90
36 Involvement of P-glycoprotein and MRP1 in resistance to cyclic tetrapeptide subfamily of histone deacetylase inhibitors in the drug-resistant osteosarcoma and Ewing's sarcoma cells. Int J Cancer 2006 0.90
37 Overexpression of PACAP in transgenic mouse pancreatic beta-cells enhances insulin secretion and ameliorates streptozotocin-induced diabetes. Diabetes 2003 0.89
38 Slow excitotoxicity in Alzheimer's disease. J Alzheimers Dis 2013 0.89
39 Interacting effect of thermoperiod and photoperiod on the eclosion rhythm in the onion fly, Delia antiqua supports the two-oscillator model. J Insect Physiol 2010 0.88
40 Chromosomal aberrations and microsatellite instability of malignant peripheral nerve sheath tumors: a study of 10 tumors from nine patients. Cancer Genet Cytogenet 2006 0.88
41 Selective cyclooxygenase-2 inhibitor prevents reduction of trabecular bone mass in collagen-induced arthritic mice in association with suppression of RANKL/OPG ratio and IL-6 mRNA expression in synovial tissues but not in bone marrow cells. J Bone Miner Metab 2008 0.88
42 Alternative surgical treatment for giant-cell reparative granuloma in the metacarpal, using phenol and ethanol adjuvant therapy. J Hand Surg Am 2007 0.87
43 Inhibition of the transcriptional function of p53 by EWS-Fli1 chimeric protein in Ewing Family Tumors. Cancer Lett 2010 0.87
44 Dedifferentiated liposarcoma with leukocytosis. A case report of G-CSF-producing soft-tissue tumors, possible association with undifferentiated liposarcoma lineage. World J Surg Oncol 2007 0.87
45 Two-step adsorption/desorption on a jungle-gym-type porous coordination polymer. Angew Chem Int Ed Engl 2007 0.87
46 Automated method for identification of patients with Alzheimer's disease based on three-dimensional MR images. Acad Radiol 2008 0.86
47 Nuclear beta-catenin correlates with cyclin D1 expression in spindle and pleomorphic sarcomas but not in synovial sarcoma. Hum Pathol 2006 0.85
48 Endothelins stimulate the production of stromelysin-1 in cultured rat astrocytes. Biochem Biophys Res Commun 2008 0.84
49 Defects in reproductive functions in PACAP-deficient female mice. Regul Pept 2002 0.84
50 PTEN/MMAC1 gene mutation is a rare event in soft tissue sarcomas without specific balanced translocations. Int J Cancer 2003 0.84
51 Low-grade fibrosarcoma of the proximal humerus. Pathol Int 2003 0.84
52 Changes in anteroposterior stability following total knee arthroplasty. J Orthop Sci 2003 0.84
53 Cyclin-dependent kinase inhibitor, flavopiridol, induces apoptosis and inhibits tumor growth in drug-resistant osteosarcoma and Ewing's family tumor cells. Int J Cancer 2007 0.83
54 Five-year evolution of a telangiectatic osteosarcoma initially managed as an aneurysmal bone cyst. Skeletal Radiol 2005 0.82
55 Transactivation of cyclin E gene by EWS-Fli1 and antitumor effects of cyclin dependent kinase inhibitor on Ewing's family tumor cells. Int J Cancer 2005 0.82
56 Thermoperiodic regulation of the circadian eclosion rhythm in the flesh fly, Sarcophaga crassipalpis. J Insect Physiol 2011 0.82
57 Altered expression of cell cycle regulators in myxofibrosarcoma, with special emphasis on their prognostic implications. Hum Pathol 2003 0.82
58 Validation of radiographic response evaluation criteria of preoperative chemotherapy for bone and soft tissue sarcomas: Japanese Orthopaedic Association Committee on Musculoskeletal Tumors Cooperative Study. J Orthop Sci 2008 0.81
59 Two metachronous tumors induced by radiation therapy: case report and review of the literature. J Neurooncol 2008 0.81
60 Serotonergic inhibition of intense jumping behavior in mice lacking PACAP (Adcyap1-/-). Ann N Y Acad Sci 2006 0.80
61 The prognostic and therapeutic relevance of p27kip1 in Ewing's family tumors. Clin Cancer Res 2004 0.80
62 Involvement of intracellular Ca2+ elevation but not cyclic AMP in PACAP-induced p38 MAP kinase activation in PC12 cells. Regul Pept 2002 0.80
63 Aneurysmal bone cyst of the capitate: case report and a review emphasizing local recurrence. Fukuoka Igaku Zasshi 2006 0.79
64 Nonossifying fibroma accompanied by pathological fracture in a 12-year-old runner. J Orthop Sports Phys Ther 2008 0.79
65 The activity of the Bone and Soft Tissue Tumor Study Group of the Japan Clinical Oncology Group. Jpn J Clin Oncol 2012 0.79
66 Trans-4-lodo,4'-boranyl-chalcone induces antitumor activity against malignant glioma cell lines in vitro and in vivo. J Neurooncol 2007 0.79
67 Solitary lymphangioma of the femur. A case report. J Orthop Sci 2002 0.79
68 A novel mutation (L250V) in the presenilin 1 gene in a Japanese familial Alzheimer's disease with myoclonus and generalized convulsion. J Neurol Sci 2003 0.78
69 PTEN and other tumor suppressor gene mutations as secondary genetic alterations in synovial sarcoma. Oncol Rep 2004 0.78
70 Intracerebroventricular administration of an endothelin ET(B)-receptor agonist increases expression of matrix metalloproteinase-2 and -9 in rat brain. J Pharmacol Sci 2010 0.78
71 High-level expression of Myrothecium verrucaria bilirubin oxidase in Pichia pastoris, and its facile purification and characterization. Protein Expr Purif 2005 0.78
72 Preoperative detection of the facial nerve by high-field magnetic resonance imaging in patients with vestibular schwannoma. Neuroradiology 2013 0.78
73 Adventitial cystic disease of the popliteal vein: report of a case. Surg Today 2006 0.78
74 Intramuscular diffuse-type giant cell tumor within the hamstring muscle. Skeletal Radiol 2006 0.77
75 Delayed onset massive oedema and deterioration in traumatic brain injury. J Clin Neurosci 2007 0.77
76 Impacts of compression on crystallization behavior of freeze-dried amorphous sucrose. J Pharm Sci 2010 0.77
77 Different spatial distribution between germinal center B and non-germinal center B primary central nervous system lymphoma revealed by magnetic resonance group analysis. Neuro Oncol 2014 0.77
78 Overexpression of PACAP in the pancreas failed to rescue early postnatal mortality in PACAP-null mice. Regul Pept 2004 0.77
79 Immunohistochemical and molecular genetics study of a granular cell astrocytoma: a case report of malignant transformation to a glioblastoma. Neuropathology 2012 0.77
80 Decreases in rat brain aquaporin-4 expression following intracerebroventricular administration of an endothelin ET B receptor agonist. Neurosci Lett 2009 0.76
81 Comprehensive gene expression profiling reveals synergistic functional networks in cerebral vessels after hypertension or hypercholesterolemia. PLoS One 2013 0.76
82 Dedifferentiated chondrosarcoma with leukocytosis and elevation of serum G-CSF. A case report. World J Surg Oncol 2006 0.75
83 Insufficiency fracture in the para-acetabulum, with features mimicking those of a malignant bone tumor. Clin Med Case Rep 2008 0.75
84 Mechanical Thrombectomy Using the Trevo ProVue in 50 Consecutive Patients with Anterior Circulation Stroke: A Single-Center Experience after Approval of the Stent Retriever in Japan. Neurol Med Chir (Tokyo) 2016 0.75
85 Influence of compression on water sorption, glass transition, and enthalpy relaxation behavior of freeze-dried amorphous sugar matrices. Int J Pharm 2011 0.75
86 Vortex scale of unsteady separation on a pitching airfoil. Ann N Y Acad Sci 2002 0.75
87 Comprehensive gene expression analyses of the rat prefrontal cortex after oxysterol treatment. J Neurochem 2013 0.75
88 Relation of surgery, tumor site, and age group to the loss of reality testing in Japanese patients with malignant tumors: a study of a hospital-based sample with a consultation-liaison service. Psychiatry Clin Neurosci 2005 0.75
89 Vascular compression caused by solitary osteochondroma: useful diagnostic methods of magnetic resonance angiography and Doppler ultrasonography. J Orthop Sci 2002 0.75
90 Glioblastoma multiforme associated with klinefelter syndrome. Neurol Med Chir (Tokyo) 2009 0.75
91 Development and application of kinetic model on biological anoxic/aerobic filter. Chemosphere 2007 0.75
92 True density analysis of a freeze-dried amorphous sugar matrix. J Pharm Sci 2008 0.75
93 T-588, a cognitive enhancer, protects against sodium nitroprusside-induced toxicity in cultured astrocytes. J Pharmacol Sci 2004 0.75
94 [Two cases of cerebral infarction due to focal irradiation for glioma in adults]. No Shinkei Geka 2015 0.75
95 Angiosarcoma arising in schwannoma of cerebellopontine angle and later associating with meningioma in a patient with neurofibromatosis type 2. Brain Tumor Pathol 2014 0.75
96 [Association of Deep Venous Thrombosis with D-dimer Values in Patients with Hemorrhagic Stroke]. No Shinkei Geka 2016 0.75
97 [Altered behavioral response to centrally acting drugs in mice lacking PACAP]. Nihon Yakurigaku Zasshi 2003 0.75