Published in Eur J Biochem on November 01, 1979
Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions. Biochem J (1999) 9.00
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The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways. Endocr Rev (2009) 3.23
Metabolic checkpoints in activated T cells. Nat Immunol (2012) 2.47
Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide. J Clin Invest (1986) 2.08
Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes. J Clin Invest (1985) 1.98
Hydrogen peroxide-induced injury of cells and its prevention by inhibitors of poly(ADP-ribose) polymerase. Proc Natl Acad Sci U S A (1986) 1.87
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Identification of unknown protein function using metabolite cocktail screening. Structure (2012) 1.62
The role of phosphometabolites in cell proliferation, energy metabolism, and tumor therapy. J Bioenerg Biomembr (1997) 1.32
Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1. Proc Natl Acad Sci U S A (2007) 1.23
Glutathione cycle activity and pyridine nucleotide levels in oxidant-induced injury of cells. J Clin Invest (1985) 1.21
Efficient retroviral infection of mammalian cells is blocked by inhibition of poly(ADP-ribose) polymerase activity. J Virol (1996) 1.15
NAD+ as a signaling molecule modulating metabolism. Cold Spring Harb Symp Quant Biol (2012) 1.12
Activation of DNA ligase by poly(ADP-ribose) in chromatin. Proc Natl Acad Sci U S A (1983) 1.03
Apoptosis in the heart: when and why? Mol Cell Biochem (1997) 1.00
Lymphocyte dysfunction after DNA damage by toxic oxygen species. A model of immunodeficiency. J Exp Med (1986) 0.99
Human autoantibodies to poly(adenosine diphosphate-ribose) polymerase. J Clin Invest (1987) 0.99
The differential cytotoxicity of RSU 1069: cell survival studies indicating interaction with DNA as a possible mode of action. Br J Cancer (1986) 0.99
Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases. Crit Rev Eukaryot Gene Expr (2014) 0.99
Poly(ADP-Ribose) polymerase 1 (PARP-1) regulates ribosomal biogenesis in Drosophila nucleoli. PLoS Genet (2012) 0.96
DNA damage induced by tumour necrosis factor-alpha in L929 cells is mediated by mitochondrial oxygen radical formation. Immunology (1995) 0.94
Blockade of PARP activity attenuates poly(ADP-ribosyl)ation but offers only partial neuroprotection against NMDA-induced cell death in the rat retina. J Neurochem (2006) 0.92
Evidence that poly(ADP-ribose) polymerase is involved in the loss of NAD from cultured rat liver cells. Biochem J (1982) 0.89
Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes. Mol Aspects Med (2013) 0.89
Cytotoxicity of 5-(3-methyl-1-triazeno)imidazole-4-carboxamide (MTIC) on Mer+, Mer+Rem- and Mer- cell lines: differential potentiation by 3-acetamidobenzamide. Br J Cancer (1988) 0.85
Metoclopramide enhances the effect of cisplatin on xenografted squamous cell carcinoma of the head and neck. Br J Cancer (1989) 0.85
Activation of ADP-ribosyltransferase in polyamine-depleted mammalian cells. Biochem J (1984) 0.84
Induction of nitric oxide synthase in L929 cells by tumour-necrosis factor alpha is prevented by inhibitors of poly(ADP-ribose) polymerase. Biochem J (1992) 0.83
Antitumour imidazotetrazines--XI: Effect of 8-carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one [CCRG 81045; M and B 39831 NSC 362856] on poly(ADP-ribose) metabolism. Br J Cancer (1985) 0.81
Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure. Pediatr Nephrol (2006) 0.79
NAD(+) Metabolism in Age-Related Hearing Loss. Aging Dis (2014) 0.79
Augmentation of NAD(+) by NQO1 attenuates cisplatin-mediated hearing impairment. Cell Death Dis (2014) 0.79
New Therapeutic Concept of NAD Redox Balance for Cisplatin Nephrotoxicity. Biomed Res Int (2016) 0.79
Hormonal stimulation of eucaryotic cell ADP-ribosylation. J Clin Invest (1981) 0.78
Emerging therapeutic roles for NAD(+) metabolism in mitochondrial and age-related disorders. Clin Transl Med (2016) 0.77
The influence of inhibitors of poly (ADP-ribose) polymerase on X-ray-induced potentially lethal damage repair. Br J Cancer Suppl (1984) 0.77
Absence of stimulation of poly(ADP-ribose) polymerase activity in patients predisposed to colon cancer. Br J Cancer (1998) 0.77
3T3-L1 preadipocyte differentiation and poly(ADP-ribose) synthetase. Mol Cell Biochem (1983) 0.76
Adenine ribo- and deoxyribonucleotide metabolism in human erythrocytes, B- and T-lymphocyte cell lines, and monocyte-macrophages. Proc Natl Acad Sci U S A (1985) 0.75
Combination Platinum-based and DNA Damage Response-targeting Cancer Therapy: Evolution and Future Directions. Curr Med Chem (2016) 0.75
Nicotinamide is an inhibitor of SIRT1 in vitro, but can be a stimulator in cells. Cell Mol Life Sci (2017) 0.75
(ADP-ribose)n participates in DNA excision repair. Nature (1980) 3.76
XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro. Nucleic Acids Res (1996) 3.51
A conjugation-like mechanism for prespore chromosome partitioning during sporulation in Bacillus subtilis. Genes Dev (1995) 2.64
Single molecule fluorescence spectroscopy at ambient temperature. Chem Rev (1999) 2.60
Prostacyclin is not a circulating hormone in man. Prostaglandins (1982) 2.46
Reduction in sympathetic nervous activity as a mechanism for hypotensive effect of propranolol. Nature (1975) 2.23
Isolation of chromosomal origins of replication in yeast. Nature (1980) 2.20
Sequence analysis of ARS elements in fission yeast. EMBO J (1988) 2.17
Automated discrete kinetic method for erythrocyte acetylcholinesterase and plasma cholinesterase. Clin Chem (1981) 2.14
Alterations of single molecule fluorescence lifetimes in near-field optical microscopy. Science (1994) 2.13
Absorption and metabolism of nicotine from cigarettes. Br Med J (1975) 2.01
Pharmacokinetics of indoramin in man. Br J Clin Pharmacol (1976) 1.97
Medically intractable, localization-related epilepsy with normal MRI: presurgical evaluation and surgical outcome in 43 patients. Epilepsia (2001) 1.96
Transformation of Schizosaccharomyces pombe by non-homologous, unstable integration of plasmids in the genome. Curr Genet (1986) 1.93
Regulation of DNA ligase activity by poly(ADP-ribose). Nature (1982) 1.91
DNA strand breaks and ADP-ribosyl transferase activation during cell differentiation. Nature (1982) 1.81
May mothers given warfarin breast-feed their infants? Br Med J (1977) 1.80
Clinical evaluation of indoramin, a new antihypertensive agent. Eur J Clin Pharmacol (1973) 1.78
Glucose intolerance in hypertensive patients treated with diuretics; a fourteen-year follow-up. Lancet (1982) 1.73
A double blind placebo controlled crossover study of prostacyclin in man. Life Sci (1979) 1.67
Clinical experience with use of ultrasound sphygmomanometer. Br Heart J (1975) 1.62
The relationship between cell growth, macromolecular synthesis and poly ADP-ribose polymerase in lymphoid cells. Exp Cell Res (1974) 1.58
How obstetricians manage hypertension in pregnancy. Br Med J (1978) 1.56
Brain concentration of propranolol in relation to hypotensive effect in the rabbit with observations on brain propranolol levels in man. J Pharmacol Exp Ther (1975) 1.56
Measurement of 6-oxo-PGF1 alpha in human plasma using gas chromatography-mass spectrometry. Prostaglandins (1979) 1.48
The Thought Control Questionnaire: a measure of individual differences in the control of unwanted thoughts. Behav Res Ther (1994) 1.44
Prostacyclin deficiency in haemolytic-uraemic syndrome. Br Med J (1980) 1.43
The importance of central adrenergic neurones in renal hypertension in rabbits. J Physiol (1974) 1.43
Increased sensitivity and accuracy of phaeochromocytoma diagnosis achieved by use of plasma-adrenaline estimations and a pentolinium-suppression test. Lancet (1981) 1.42
The acetylation of insulin. Biochem J (1971) 1.42
Analgesia and satisfaction in childbirth (the Queen Charlotte's 1000 Mother Survey). Lancet (1982) 1.39
Anatomic correlates of memory from intracarotid amobarbital injections with technetium Tc 99m hexamethylpropyleneamine oxime SPECT. Arch Neurol (1993) 1.37
Prostacyclin in pregnancy. Br Med J (1980) 1.35
Evaluation of heterologous ARS activity in S. cerevisiae using cloned DNA from S. pombe. Nucleic Acids Res (1985) 1.33
Single-molecule identification in flowing sample streams by fluorescence burst size and intraburst fluorescence decay rate. Anal Chem (1998) 1.32
Improved plasmid vectors for the production of multiple fluorescent protein fusions in Bacillus subtilis. Gene (2001) 1.29
Paralimbic hypoperfusion in unipolar depression. J Nucl Med (1994) 1.27
Prostacyclin deficiency in thrombotic thrombocytopenic purpura. Lancet (1979) 1.27
The consumers' attitude to obstetric care. Br J Obstet Gynaecol (1984) 1.27
Risk factors for breast cancer. Pollutants and pesticides may be important. BMJ (1994) 1.23
Deterioration of glucose tolerance in hypertensive patients on prolonged diuretic treatment. Lancet (1976) 1.21
The significance of antibodies to poly(adenosine diphosphate-ribose) in systemic lupus erythematosus. Clin Exp Immunol (1979) 1.21
The interaction of core histones with DNA: equilibrium binding studies. Nucleic Acids Res (1978) 1.21
Studies of the morphology and tumorigenicity of experimental brain tumours in tissue culture. Br J Exp Pathol (1976) 1.20
The drawbacks of research ethics committees. J Med Ethics (1982) 1.20
Day surgery for cervical microdiscectomy: is it safe and effective? J Spinal Disord (1996) 1.18
The gene responsible for Werner syndrome may be a cell division "counting" gene. Proc Natl Acad Sci U S A (1993) 1.17
Profile of autoantibodies in the serum of patients with tuberculosis, klebsiella and other gram-negative infections. Clin Exp Immunol (1987) 1.17
Letters: Phase equilibria of oxygen in blood-gas control samples. Clin Chem (1975) 1.17
The enhancement of cytotoxicity of N-methyl-N-nitrosourea and of gamma-radiation by inhibitors of poly(ADP-ribose) polymerase. Eur J Biochem (1980) 1.17
Poly (ADP-ribose) polymerase activity in nucleotide permeable cells. FEBS Lett (1978) 1.16
Efficient retroviral infection of mammalian cells is blocked by inhibition of poly(ADP-ribose) polymerase activity. J Virol (1996) 1.15
Factors influencing the incidence of neonatal jaundice. Br Med J (1978) 1.15
A protein having similarity with methylmalonyl-CoA mutase is required for the assimilation of methanol and ethanol by Methylobacterium extorquens AM1. Microbiology (1996) 1.14
Distinct pattern of TP53 mutations in squamous cell carcinoma of the esophagus in Iran. Oncogene (2001) 1.12
ADP-ribosylation is involved in the integration of foreign DNA into the mammalian cell genome. Nucleic Acids Res (1988) 1.12
Decompressive lumbar laminectomy for spinal stenosis. J Neurosurg (1993) 1.10
Studies on autoantibodies to poly (adenosine diphosphate-ribose) in SLE and other autoimmune diseases. Ann Rheum Dis (1982) 1.09
Acute thermoregulatory and cardiovascular effects of 6-hydroxydopamine administered centrally in rabbits and cats. Br J Pharmacol (1972) 1.09
Long-term prospective study of lumbosacral discectomy. J Neurosurg (1987) 1.09
Intradermal immunization with a bovine herpesvirus-1 DNA vaccine induces protective immunity in cattle. J Gen Virol (1998) 1.06
The effect of inhibition of (ADP-ribose)n biosynthesis on DNA repair assayed by the nucleoid technique. Eur J Biochem (1981) 1.05
Cardiovascular effects of intracerebroventricular d-, l- and dl-propranolol in the conscious rabbit. J Pharmacol Exp Ther (1974) 1.05
Intra-individual variation in plasma and erythrocyte cholinesterase activities and the monitoring of uptake of organo-phosphate pesticides. J Soc Occup Med (1989) 1.03
BB-10010: an active variant of human macrophage inflammatory protein-1 alpha with improved pharmaceutical properties. Blood (1995) 1.01
The effect of gamma radiation and neocarzinostatin on NAD and ATP levels in mouse leukaemia cells. Biochim Biophys Acta (1978) 1.01
Protein-nucleoside contacts in the interaction between the replication terminator protein of Bacillus subtilis and the DNA terminator. Mol Microbiol (1993) 0.99
Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ (1995) 0.99
Excretion of anticoagulants in human milk. N Engl J Med (1977) 0.98
Poly(adenosine diphosphate ribose) polymerase in Physarum polycephalum. Biochem J (1975) 0.98
Pharmacokinetic and metabolism studies using microdialysis sampling. J Pharm Sci (1999) 0.97
Lumbar diskectomy for recurrent disk herniation. J Spinal Disord (1994) 0.97
Treatment of bronchial asthma with terfenadine; a randomized controlled trial. Br J Clin Pharmacol (1987) 0.97
Site-directed mutagenesis and X-ray crystallography of the PQQ-containing quinoprotein methanol dehydrogenase and its electron acceptor, cytochrome c(L). Biochemistry (2001) 0.97
Dynamic localization of membrane proteins in Bacillus subtilis. Microbiology (2004) 0.96
Structure of ribonuclease. Nature (1967) 0.95
Carbamyl- and methylthiocarbamylinsulins. Biochim Biophys Acta (1972) 0.95
Affinity chromatography of nuclear enzymes. Biochem Soc Trans (1976) 0.94
The expression of proliferation-dependent antigens during the lifespan of normal and progeroid human fibroblasts in culture. J Cell Sci (1994) 0.94
Clinical pharmacology and potential of prostacyclin. Br Med Bull (1983) 0.94
Stimulation of poly(ADP-ribose) polymerase activity by the anti-tumour antibiotic, streptozotocin. Biochem Biophys Res Commun (1975) 0.94
Prevention of DOCA saline hypertension by central 6-hydroxydopamine: role of saline intake. Br J Pharmacol (1975) 0.93
Prostacyclin stimulates the renin angiotensin aldosterone system in man. J Clin Endocrinol Metab (1979) 0.93
Purification and properties of poly(ADP-ribose) polymerase from pig-thymus nuclei. Eur J Biochem (1978) 0.93
Prostacyclin and pre-eclampsia. Lancet (1981) 0.92
Poly (ADP-ribose) glycohydrolase in mouse fibroblast cells (LS cells). FEBS Lett (1973) 0.92
Circulating prostacyclin may be reduced in diabetes. Lancet (1980) 0.92
Poly(adenosine diphosphate ribose) polymerase and deoxyribonucleic acid damage [proceedings]. Biochem Soc Trans (1977) 0.92
Post-synthetic modifications of nuclear macromolecules. Biochem Soc Symp (1977) 0.92
Poly(adenosine diphosphoribose) polymerase in mammalian nuclei. Characterization of the activity in mouse fibroblasts (LS cells). Eur J Biochem (1973) 0.91