Published in Virol J on August 21, 2012
The influenza virus NS1 protein as a therapeutic target. Antiviral Res (2013) 0.99
Nucleolin interacts with the dengue virus capsid protein and plays a role in formation of infectious virus particles. J Virol (2013) 0.90
Identification of adaptive mutations in the influenza A virus non-structural 1 gene that increase cytoplasmic localization and differentially regulate host gene expression. PLoS One (2013) 0.80
Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication. Virol J (2014) 0.78
The R35 residue of the influenza A virus NS1 protein has minimal effects on nuclear localization but alters virus replication through disrupting protein dimerization. Virology (2014) 0.77
Interaction of Host Nucleolin with Influenza A Virus Nucleoprotein in the Early Phase of Infection Limits the Late Viral Gene Expression. PLoS One (2016) 0.76
Nuclear Translocation of Crk Adaptor Proteins by the Influenza A Virus NS1 Protein. Viruses (2016) 0.75
Generation and Comprehensive Analysis of Host Cell Interactome of the PA Protein of the Highly Pathogenic H5N1 Avian Influenza Virus in Mammalian Cells. Front Microbiol (2017) 0.75
Nucleolin interacts with influenza A nucleoprotein and contributes to viral ribonucleoprotein complexes nuclear trafficking and efficient influenza viral replication. Sci Rep (2016) 0.75
The Subcellular Localization and Functional Analysis of Fibrillarin2, a Nucleolar Protein in Nicotiana benthamiana. Biomed Res Int (2016) 0.75
Nucleolin-binding by ErbB2 enhances tumorigenicity of ErbB2-positive breast cancer. Oncotarget (2016) 0.75
Influenza A Virus Virulence Depends on Two Amino Acids in the N-Terminal Domain of Its NS1 Protein To Facilitate Inhibition of the RNA-Dependent Protein Kinase PKR. J Virol (2017) 0.75
Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans. Science (2009) 25.61
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature (2006) 22.65
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates. Science (2006) 16.00
Generation of influenza A viruses entirely from cloned cDNAs. Proc Natl Acad Sci U S A (1999) 14.90
Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. Cancer Res (1982) 11.72
The multifunctional nucleolus. Nat Rev Mol Cell Biol (2007) 7.08
Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes. Nature (1988) 6.28
Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc Natl Acad Sci U S A (2002) 6.09
Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs. Mol Cell (1998) 5.60
Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host Microbe (2009) 5.12
Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus. J Virol (2006) 4.88
HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: implications for HIV-1 latency. Cell (1991) 4.61
An overlapping protein-coding region in influenza A virus segment 3 modulates the host response. Science (2012) 3.70
The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathway. Proc Natl Acad Sci U S A (2006) 3.50
Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery. EMBO J (1999) 3.35
Replication and plaque assay of influenza virus in an established line of canine kidney cells. Appl Microbiol (1968) 3.04
Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA. Virology (2006) 3.00
Identification of sequences important in the nucleolar localization of human immunodeficiency virus Rev: relevance of nucleolar localization to function. J Virol (1990) 2.63
Localization, trafficking, and temperature-dependence of the Aequorea green fluorescent protein in cultured vertebrate cells. Proc Natl Acad Sci U S A (1995) 2.35
A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis. Virology (2007) 2.30
Structural and functional characterization of the human immunodeficiency virus rev protein. J Acquir Immune Defic Syndr (1989) 2.10
Sensing cellular stress: another new function for the nucleolus? Sci STKE (2004) 2.09
The CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target. J Virol (2006) 2.05
Specific complex of human immunodeficiency virus type 1 rev and nucleolar B23 proteins: dissociation by the Rev response element. Mol Cell Biol (1991) 2.02
RNA viruses: hijacking the dynamic nucleolus. Nat Rev Microbiol (2007) 1.95
The 3'-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo. RNA (2001) 1.94
Regulation of a nuclear export signal by an adjacent inhibitory sequence: the effector domain of the influenza virus NS1 protein. Proc Natl Acad Sci U S A (1998) 1.94
Nuclear and nucleolar targeting of influenza A virus NS1 protein: striking differences between different virus subtypes. J Virol (2007) 1.92
Nucleolus: the fascinating nuclear body. Histochem Cell Biol (2007) 1.87
In search of nonribosomal nucleolar protein function and regulation. J Cell Biol (2009) 1.84
Nucleolar targeting: the hub of the matter. EMBO Rep (2009) 1.82
The moving parts of the nucleolus. Histochem Cell Biol (2005) 1.81
Influence of host species on the evolution of the nonstructural (NS) gene of influenza A viruses. Virus Res (1998) 1.78
X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus. Nature (2008) 1.77
NF-{kappa}B is transported into the nucleus by importin {alpha}3 and importin {alpha}4. J Biol Chem (2005) 1.76
Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression. J Virol (2006) 1.75
The contribution of nuclear compartmentalization to gene regulation. Cell (2002) 1.70
Conventional and nonconventional roles of the nucleolus. Int Rev Cytol (2002) 1.43
The nucleolus: structure/function relationship in RNA metabolism. Wiley Interdiscip Rev RNA (2010) 1.37
Influenza virus inhibits cleavage of the HSP70 pre-mRNAs at the polyadenylation site. Virology (1999) 1.29
Retinoic acid inducible gene-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines. Microbes Infect (2006) 1.22
Avian and 1918 Spanish influenza a virus NS1 proteins bind to Crk/CrkL Src homology 3 domains to activate host cell signaling. J Biol Chem (2007) 1.22
Cytosolic, nuclear and nucleolar localization signals determine subcellular distribution and activity of the NF-kappaB inducing kinase NIK. J Cell Sci (2004) 1.16
Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation. J Biol Chem (2007) 1.08
Nuclear and nucleolar localization of Saccharomyces cerevisiae ribosomal proteins S22 and S25. FEBS Lett (1999) 0.92
Influenza A virus non-structural protein 1 (NS1) interacts with cellular multifunctional protein nucleolin during infection. Biochem Biophys Res Commun (2007) 0.92
A B23-interacting sequence as a tool to visualize protein interactions in a cellular context. J Cell Sci (2006) 0.91
Sequence requirement for nucleolar localization of rat ribosomal protein L31. Eur J Cell Biol (1996) 0.90
Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells. Eur J Immunol (2004) 3.25
AS03 adjuvanted AH1N1 vaccine associated with an abrupt increase in the incidence of childhood narcolepsy in Finland. PLoS One (2012) 2.67
IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28, and IL-29. J Immunol (2005) 2.63
IFN regulatory factor family members differentially regulate the expression of type III IFN (IFN-lambda) genes. J Immunol (2007) 2.40
Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20. J Biol Chem (2005) 2.27
Increased incidence and clinical picture of childhood narcolepsy following the 2009 H1N1 pandemic vaccination campaign in Finland. PLoS One (2012) 2.23
Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage. J Virol (2006) 2.15
Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity. J Virol (2004) 2.06
Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells. J Virol (2005) 1.97
Nuclear and nucleolar targeting of influenza A virus NS1 protein: striking differences between different virus subtypes. J Virol (2007) 1.92
Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells. J Leukoc Biol (2007) 1.90
IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response. J Immunol (2002) 1.89
Nucleolus: the fascinating nuclear body. Histochem Cell Biol (2007) 1.87
Arginine/lysine-rich nuclear localization signals mediate interactions between dimeric STATs and importin alpha 5. J Biol Chem (2002) 1.86
Full-Genome Sequences of Influenza A(H1N1)pdm09 Viruses Isolated from Finnish Patients from 2009 to 2013. Genome Announc (2014) 1.82
Importin alpha nuclear localization signal binding sites for STAT1, STAT2, and influenza A virus nucleoprotein. J Biol Chem (2003) 1.81
NF-{kappa}B is transported into the nucleus by importin {alpha}3 and importin {alpha}4. J Biol Chem (2005) 1.76
Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression. J Virol (2006) 1.75
Genetic diversity of the 2009 pandemic influenza A(H1N1) viruses in Finland. PLoS One (2010) 1.74
Pandemic H1N1 2009 influenza A virus induces weak cytokine responses in human macrophages and dendritic cells and is highly sensitive to the antiviral actions of interferons. J Virol (2009) 1.72
IL-21 in synergy with IL-15 or IL-18 enhances IFN-gamma production in human NK and T cells. J Immunol (2003) 1.70
IFN-alpha enhances TLR3-mediated antiviral cytokine expression in human endothelial and epithelial cells by up-regulating TLR3 expression. J Immunol (2005) 1.67
Virus-infection or 5'ppp-RNA activates antiviral signal through redistribution of IPS-1 mediated by MFN1. PLoS Pathog (2010) 1.66
Induction of cytokine expression by herpes simplex virus in human monocyte-derived macrophages and dendritic cells is dependent on virus replication and is counteracted by ICP27 targeting NF-kappaB and IRF-3. J Gen Virol (2006) 1.66
Streptococcus pyogenes and Lactobacillus rhamnosus differentially induce maturation and production of Th1-type cytokines and chemokines in human monocyte-derived dendritic cells. J Leukoc Biol (2004) 1.55
Minor changes in the hemagglutinin of influenza A(H1N1)2009 virus alter its antigenic properties. PLoS One (2011) 1.55
Expression of hepatitis C virus core protein inhibits interferon-induced nuclear import of STATs. J Med Virol (2004) 1.55
Regulation of virus-induced IL-12 and IL-23 expression in human macrophages. J Immunol (2002) 1.50
Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways. Nat Immunol (2012) 1.48
Cyclin-dependent kinases govern formation and maintenance of the nucleolus. J Cell Biol (2002) 1.47
The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats. EMBO J (2010) 1.40
The nucleolus: structure/function relationship in RNA metabolism. Wiley Interdiscip Rev RNA (2010) 1.37
IFN-alpha beta released by Mycobacterium tuberculosis-infected human dendritic cells induces the expression of CXCL10: selective recruitment of NK and activated T cells. J Immunol (2003) 1.34
Multiple signaling pathways contribute to synergistic TLR ligand-dependent cytokine gene expression in human monocyte-derived macrophages and dendritic cells. J Leukoc Biol (2009) 1.34
Cytokine and contact-dependent activation of natural killer cells by influenza A or Sendai virus-infected macrophages. J Gen Virol (2004) 1.31
RIG-I-mediated activation of p38 MAPK is essential for viral induction of interferon and activation of dendritic cells: dependence on TRAF2 and TAK1. J Biol Chem (2009) 1.30
TNF-alpha and IFN-alpha enhance influenza-A-virus-induced chemokine gene expression in human A549 lung epithelial cells. Virology (2005) 1.29
Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and target-gene expression during human monocyte/macrophage differentiation. J Leukoc Biol (2002) 1.28
IFN-alpha regulates Toll-like receptor-mediated IL-27 gene expression in human macrophages. J Leukoc Biol (2007) 1.25
Emerging concepts of nucleolar assembly. J Cell Sci (2002) 1.24
Quantitative subcellular proteome and secretome profiling of influenza A virus-infected human primary macrophages. PLoS Pathog (2011) 1.22
The interferon-inducible RNA helicase, mda-5, is involved in measles virus-induced expression of antiviral cytokines. Microbes Infect (2006) 1.22
Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis. J Cell Sci (2009) 1.22
Retinoic acid inducible gene-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines. Microbes Infect (2006) 1.22
Avian and 1918 Spanish influenza a virus NS1 proteins bind to Crk/CrkL Src homology 3 domains to activate host cell signaling. J Biol Chem (2007) 1.22
Probiotic intervention has strain-specific anti-inflammatory effects in healthy adults. World J Gastroenterol (2008) 1.21
Lactobacilli and streptococci induce inflammatory chemokine production in human macrophages that stimulates Th1 cell chemotaxis. J Leukoc Biol (2003) 1.21
Tracking the interactions of rRNA processing proteins during nucleolar assembly in living cells. Mol Biol Cell (2005) 1.18
Differential expression of IFN regulatory factor 4 gene in human monocyte-derived dendritic cells and macrophages. J Immunol (2005) 1.15
IL-21 enhances SOCS gene expression and inhibits LPS-induced cytokine production in human monocyte-derived dendritic cells. J Leukoc Biol (2006) 1.13
Severe acute respiratory syndrome coronavirus fails to activate cytokine-mediated innate immune responses in cultured human monocyte-derived dendritic cells. J Virol (2005) 1.11
Potentially probiotic bacteria induce efficient maturation but differential cytokine production in human monocyte-derived dendritic cells. World J Gastroenterol (2008) 1.11
NF-kappaB p52, RelB and c-Rel are transported into the nucleus via a subset of importin alpha molecules. Cell Signal (2008) 1.09
Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression. Virol J (2006) 1.08
Probiotic Leuconostoc mesenteroides ssp. cremoris and Streptococcus thermophilus induce IL-12 and IFN-gamma production. World J Gastroenterol (2008) 1.08
Aurora B -TACC1 protein complex in cytokinesis. Oncogene (2004) 1.07
Multiple NF-kappaB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells. J Immunol (2007) 1.07
The unusually large Plasmodium telomerase reverse-transcriptase localizes in a discrete compartment associated with the nucleolus. Nucleic Acids Res (2005) 1.06
Involvement of TBK1 and IKKepsilon in lipopolysaccharide-induced activation of the interferon response in primary human macrophages. Eur J Immunol (2007) 1.05
Nuclear translocation of hypoxia-inducible factors (HIFs): involvement of the classical importin alpha/beta pathway. Biochim Biophys Acta (2008) 1.05
IFN-alpha regulates IL-21 and IL-21R expression in human NK and T cells. J Leukoc Biol (2004) 1.03
Analysis of influenza B Virus NS1 protein trafficking reveals a novel interaction with nuclear speckle domains. J Virol (2008) 1.03
Cytokine responses in cord blood predict the severity of later respiratory syncytial virus infection. J Allergy Clin Immunol (2009) 0.99
Cellular immunity to mumps virus in young adults 21 years after measles-mumps-rubella vaccination. J Infect Dis (2007) 0.97
Activation, cytokine production, and intracellular survival of bacteria in Salmonella-infected human monocyte-derived macrophages and dendritic cells. J Leukoc Biol (2005) 0.96
No serological evidence of influenza A H1N1pdm09 virus infection as a contributing factor in childhood narcolepsy after Pandemrix vaccination campaign in Finland. PLoS One (2013) 0.96
Innate immune responses in human monocyte-derived dendritic cells are highly dependent on the size and the 5' phosphorylation of RNA molecules. J Immunol (2011) 0.96
Live Lactobacillus rhamnosus and Streptococcus pyogenes differentially regulate Toll-like receptor (TLR) gene expression in human primary macrophages. J Leukoc Biol (2008) 0.95
The effect of probiotics on respiratory infections and gastrointestinal symptoms during training in marathon runners. Int J Sport Nutr Exerc Metab (2007) 0.95
TLR ligands induce synergistic interferon-β and interferon-λ1 gene expression in human monocyte-derived dendritic cells. Mol Immunol (2010) 0.95
Subcellular localization of SREBP1 depends on its interaction with the C-terminal region of wild-type and disease related A-type lamins. Exp Cell Res (2011) 0.94
Obatoclax, saliphenylhalamide, and gemcitabine inhibit influenza a virus infection. J Biol Chem (2012) 0.94
Hepatitis C virus core, NS3, NS4B and NS5A are the major immunogenic proteins in humoral immunity in chronic HCV infection. Virol J (2009) 0.94
Compartmentation of the nucleolar processing proteins in the granular component is a CK2-driven process. Mol Biol Cell (2006) 0.93
Regulators of nucleolar functions. Prog Cell Cycle Res (2003) 0.92
Dynamics and compartmentation of the nucleolar processing machinery. Exp Cell Res (2004) 0.91
A B23-interacting sequence as a tool to visualize protein interactions in a cellular context. J Cell Sci (2006) 0.91
In situ XRD investigation of the evolution of alumina-supported cobalt catalysts under realistic conditions of Fischer-Tropsch synthesis. Chem Commun (Camb) (2009) 0.91
Streptococcus pyogenes activates human plasmacytoid and myeloid dendritic cells. J Leukoc Biol (2007) 0.89
Incoming influenza A virus evades early host recognition, while influenza B virus induces interferon expression directly upon entry. J Virol (2012) 0.89
Interferon-alpha inhibits Stat5 DNA-binding in IL-2 stimulated primary T-lymphocytes. Eur J Biochem (2002) 0.89
Critical immunological pathways are downregulated in APECED patient dendritic cells. J Mol Med (Berl) (2008) 0.89
Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKε and TBK1 functions. J Med Virol (2012) 0.89
Transcript profiles of dendritic cells of PLOSL patients link demyelinating CNS disorders with abnormalities in pathways of actin bundling and immune response. J Mol Med (Berl) (2007) 0.89
Fibrillarin and Nop56 interact before being co-assembled in box C/D snoRNPs. Exp Cell Res (2009) 0.89