Published in Evid Based Complement Alternat Med on August 08, 2012
Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells. PLoS One (2014) 0.81
Cidan inhibits liver cancer cell growth by reducing COX-2 and VEGF expression and cell cycle arrest. Exp Ther Med (2015) 0.75
THE RETINOBLASTOMA PROTEIN: A MASTER TUMOR SUPPRESSOR ACTS AS A LINK BETWEEN CELL CYCLE AND CELL ADHESION. Cell Health Cytoskelet (2014) 0.75
Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer. Int J Mol Sci (2017) 0.75
Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul (1984) 35.22
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat Rev Drug Discov (2008) 7.64
Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153). Mol Cell Biol (1996) 5.01
Generalized equations for the analysis of inhibitions of Michaelis-Menten and higher-order kinetic systems with two or more mutually exclusive and nonexclusive inhibitors. Eur J Biochem (1981) 3.01
Mammalian stress response: induction of the glucose-regulated protein family. Curr Opin Cell Biol (1992) 2.70
Anti-cancer natural products isolated from chinese medicinal herbs. Chin Med (2011) 1.39
Curcumin induces pro-apoptotic endoplasmic reticulum stress in human leukemia HL-60 cells. Biochem Biophys Res Commun (2006) 1.18
Celastrol acts as a potent antimetastatic agent targeting beta1 integrin and inhibiting cell-extracellular matrix adhesion, in part via the p38 mitogen-activated protein kinase pathway. J Pharmacol Exp Ther (2010) 1.11
Ganoderic acid DM, a natural triterpenoid, induces DNA damage, G1 cell cycle arrest and apoptosis in human breast cancer cells. Fitoterapia (2011) 1.06
Simultaneous determination of 11 characteristic components in three species of Curcuma rhizomes using pressurized liquid extraction and high-performance liquid chromatography. J Chromatogr A (2006) 1.03
Triptolide (TPL) inhibits global transcription by inducing proteasome-dependent degradation of RNA polymerase II (Pol II). PLoS One (2011) 1.02
Identification and quantitation of eleven sesquiterpenes in three species of Curcuma rhizomes by pressurized liquid extraction and gas chromatography-mass spectrometry. J Pharm Biomed Anal (2005) 0.98
The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells. Invest New Drugs (2010) 0.93
Potential anti-cancer activities of Furanodiene, a Sesquiterpene from Curcuma wenyujin. Am J Chin Med (2009) 0.91
Synergistic anti-cancer activity by the combination of TRAIL/APO-2L and celastrol. Cancer Invest (2010) 0.90
Furanodiene induces G2/M cell cycle arrest and apoptosis through MAPK signaling and mitochondria-caspase pathway in human hepatocellular carcinoma cells. Cancer Biol Ther (2007) 0.89
Induction of apoptosis by furanodiene in HL60 leukemia cells through activation of TNFR1 signaling pathway. Cancer Lett (2008) 0.84
The short-time treatment with curcumin sufficiently decreases cell viability, induces apoptosis and copper enhances these effects in multidrug-resistant K562/A02 cells. Mol Cell Biochem (2011) 0.84
Molecular genetic and chemical assessment of Rhizoma Curcumae in China. J Agric Food Chem (2005) 0.81
2010 Consensus on Lung Cancer, new clinical recommendations and current status of biomarker assessment--first-line therapy. Eur J Cancer (2011) 0.81
[A randomized clinical trial on taxol plus oxaliplatin versus taxol plus cisplatin as first-line treatment in advanced non-small cell lung cancer]. Zhongguo Fei Ai Za Zhi (2006) 0.80
[Clinical efficacy and adverse effects of taxol plus carboplatin or gemcitabine plus carboplatin in patients with advanced non-small-cell lung carcinoma]. Zhonghua Yi Xue Za Zhi (2010) 0.78
The angiogenic effects of Angelica sinensis extract on HUVEC in vitro and zebrafish in vivo. J Cell Biochem (2008) 1.34
Multi-target drugs: the trend of drug research and development. PLoS One (2012) 1.28
Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae--a review. J Ethnopharmacol (2012) 1.26
Structure-activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities. Bioorg Med Chem (2008) 1.22
The natural compound n-butylidenephthalide derived from the volatile oil of Radix Angelica sinensis inhibits angiogenesis in vitro and in vivo. Angiogenesis (2011) 1.20
Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/ß-catenin signaling. Int J Oncol (2010) 1.18
Alkaloids isolated from natural herbs as the anticancer agents. Evid Based Complement Alternat Med (2012) 1.13
Angiogenic effect of saponin extract from Panax notoginseng on HUVECs in vitro and zebrafish in vivo. Phytother Res (2009) 1.12
A traditional Chinese medicine formulation consisting of Rhizoma Corydalis and Rhizoma Curcumae exerts synergistic anti-tumor activity. Oncol Rep (2009) 1.10
Ganoderic acid DM, a natural triterpenoid, induces DNA damage, G1 cell cycle arrest and apoptosis in human breast cancer cells. Fitoterapia (2011) 1.06
Panax notoginseng reduces atherosclerotic lesions in ApoE-deficient mice and inhibits TNF-alpha-induced endothelial adhesion molecule expression and monocyte adhesion. J Agric Food Chem (2009) 1.06
Chemical characteristics of three medicinal plants of the Panax genus determined by HPLC-ELSD. J Sep Sci (2007) 1.05
Fast-track surgery could improve postoperative recovery in radical total gastrectomy patients. World J Gastroenterol (2013) 1.02
Essential oil of Curcuma wenyujin induces apoptosis in human hepatoma cells. World J Gastroenterol (2008) 1.01
Medicinal compounds with antiepileptic/anticonvulsant activities. Epilepsia (2013) 0.99
Anti-influenza virus activities of flavonoids from the medicinal plant Elsholtzia rugulosa. Planta Med (2008) 0.97
Terpenoids: natural products for cancer therapy. Expert Opin Investig Drugs (2012) 0.95
Screening of anti-platelet aggregation agents from Panax notoginseng using human platelet extraction and HPLC-DAD-ESI-MS/MS. J Sep Sci (2008) 0.95
Herbal medicines for the prevention of alcoholic liver disease: a review. J Ethnopharmacol (2012) 0.93
Naphthalimides induce G(2) arrest through the ATM-activated Chk2-executed pathway in HCT116 cells. Neoplasia (2009) 0.93
Characterization of metabolism and in vitro permeability study of notoginsenoside R1 from Radix notoginseng. J Agric Food Chem (2010) 0.93
Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study. Xenobiotica (2010) 0.90
Platycodin D induces apoptosis, and inhibits adhesion, migration and invasion in HepG2 hepatocellular carcinoma cells. Asian Pac J Cancer Prev (2014) 0.89
Chemical differentiation of Da-Cheng-Qi-Tang, a Chinese medicine formula, prepared by traditional and modern decoction methods using UPLC/Q-TOFMS-based metabolomics approach. J Pharm Biomed Anal (2013) 0.89
In vitro anti-influenza viral activities of constituents from Caesalpinia sappan. Planta Med (2009) 0.89
Radix Astragali extract promotes angiogenesis involving vascular endothelial growth factor receptor-related phosphatidylinositol 3-kinase/Akt-dependent pathway in human endothelial cells. Phytother Res (2009) 0.89
Preparative isolation and purification of six volatile compounds from essential oil of Curcuma wenyujin using high-performance centrifugal partition chromatography. J Sep Sci (2010) 0.89
Anti-angiogenic effect of furanodiene on HUVECs in vitro and on zebrafish in vivo. J Ethnopharmacol (2011) 0.88
Angiogenic pathway inhibition of Corydalis yanhusuo and berberine in human umbilical vein endothelial cells. Oncol Res (2009) 0.88
Anatomic study of fabella and its surrounding structures in a Chinese population. Surg Radiol Anat (2011) 0.87
Anti-proliferative and pro-apoptotic effect of Smilax glabra Roxb. extract on hepatoma cell lines. Chem Biol Interact (2007) 0.87
Quinones derived from plant secondary metabolites as anti-cancer agents. Anticancer Agents Med Chem (2013) 0.87
Cardamonin inhibits angiotensin II-induced vascular smooth muscle cell proliferation and migration by downregulating p38 MAPK, Akt, and ERK phosphorylation. J Nat Med (2014) 0.87
Synergistic anti-cancer activity of the combination of dihydroartemisinin and doxorubicin in breast cancer cells. Pharmacol Rep (2013) 0.87
Yanhusuo extract inhibits metastasis of breast cancer cells by modulating mitogen-activated protein kinase signaling pathways. Oncol Rep (2008) 0.87
Comparative study on saponin fractions from Panax notoginseng inhibiting inflammation-induced endothelial adhesion molecule expression and monocyte adhesion. Chin Med (2011) 0.86
Inhibition of TNF-α-mediated endothelial cell-monocyte cell adhesion and adhesion molecules expression by the resveratrol derivative, trans-3,5,4'-trimethoxystilbene. Phytother Res (2010) 0.86
Salvicine inactivates beta 1 integrin and inhibits adhesion of MDA-MB-435 cells to fibronectin via reactive oxygen species signaling. Mol Cancer Res (2008) 0.84
Salvicine triggers DNA double-strand breaks and apoptosis by GSH-depletion-driven H2O2 generation and topoisomerase II inhibition. Free Radic Biol Med (2008) 0.84
Furanodiene enhances tamoxifen-induced growth inhibitory activity of ERa-positive breast cancer cells in a PPARγ independent manner. J Cell Biochem (2012) 0.84
Anatomic study of popliteus complex of the knee in a Chinese population. Anat Sci Int (2011) 0.83
Bisdemethoxycurcumin suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways. Pharmacol Rep (2013) 0.83
Quality evaluation of Ganoderma through simultaneous determination of nine triterpenes and sterols using pressurized liquid extraction and high performance liquid chromatography. J Sep Sci (2006) 0.83
Rapid determination of pesticide residues in herbs using selective pressurized liquid extraction and fast gas chromatography coupled with mass spectrometry. J Sep Sci (2012) 0.83
Glycyrrhetinic Acid triggers a protective autophagy by activation of extracellular regulated protein kinases in hepatocellular carcinoma cells. J Agric Food Chem (2014) 0.82
Public funding and private investment for R&D: a survey in China's pharmaceutical industry. Health Res Policy Syst (2014) 0.82
Pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline. Acta Pharmacol Sin (2003) 0.82
Chemical investigation of saponins in different parts of Panax notoginseng by pressurized liquid extraction and liquid chromatography-electrospray ionization-tandem mass spectrometry. Molecules (2012) 0.82
Ganoderiol A-enriched extract suppresses migration and adhesion of MDA-MB-231 cells by inhibiting FAK-SRC-paxillin cascade pathway. PLoS One (2013) 0.81
Anti-cancer properties of triterpenoids isolated from Ganoderma lucidum - a review. Expert Opin Investig Drugs (2013) 0.81
Fatty acid variability in three medicinal herbs of Panax species. Chem Cent J (2013) 0.81
Effect of resveratrol on proliferation and differentiation of embryonic cardiomyoblasts. Biochem Biophys Res Commun (2007) 0.81
Arjunic acid, a strong free radical scavenger from Terminalia arjuna. Am J Chin Med (2008) 0.81
Furanodiene presents synergistic anti-proliferative activity with paclitaxel via altering cell cycle and integrin signaling in 95-D lung cancer cells. Phytother Res (2013) 0.81
IC-4, a new irreversible EGFR inhibitor, exhibits prominent anti-tumor and anti-angiogenesis activities. Cancer Lett (2013) 0.81
A new compound from Gastrodia elata Blume. J Asian Nat Prod Res (2002) 0.81
CAR-mediated up-regulation of CYP3A4 expression in LS174T cells by Chinese herbal compounds. Drug Metab Pharmacokinet (2011) 0.80
Calcium signal-initiated early activation of NF-kappaB in neurons is a neuroprotective event in response to kainic acid-induced excitotoxicity. Biochemistry (Mosc) (2010) 0.80
Characterization of metabolism of (+)-praeruptorin B and (+)-praeruptorin E in human and rat liver microsomes by liquid chromatography coupled with ion trap mass spectrometry and time-of-flight mass spectrometry. Rapid Commun Mass Spectrom (2011) 0.79
Synergistic up-regulation of muscle LIM protein expression in C2C12 and NIH3T3 cells by myogenin and MEF2C. Mol Genet Genomics (2008) 0.79
Baicalein Triggers Autophagy and Inhibits the Protein Kinase B/Mammalian Target of Rapamycin Pathway in Hepatocellular Carcinoma HepG2 Cells. Phytother Res (2015) 0.78
Bisdemethoxycurcumin Increases Sirt1 to Antagonize t-BHP-Induced Premature Senescence in WI38 Fibroblast Cells. Evid Based Complement Alternat Med (2013) 0.78
The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine. J Pharm Biomed Anal (2007) 0.78
In vitro pharmacokinetic characterization of mulberroside A, the main polyhydroxylated stilbene in mulberry (Morus alba L.), and its bacterial metabolite oxyresveratrol in traditional oral use. J Agric Food Chem (2012) 0.78
Pharmacokinetic evidence on the contribution of intestinal bacterial conversion to beneficial effects of astragaloside IV, a marker compound of astragali radix, in traditional oral use of the herb. Drug Metab Pharmacokinet (2012) 0.78
[Research progress in chemical communication among insect-resistant genetically modified plants, insect pests and natural enemies]. Ying Yong Sheng Tai Xue Bao (2014) 0.78