Published in J Surg Res on August 25, 2012
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The metabolomic window into hepatobiliary disease. J Hepatol (2013) 1.24
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A comprehensive investigation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism in the mouse using a multivariate data analysis approach. Chem Res Toxicol (2007) 1.17
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Identification of noninvasive biomarkers for alcohol-induced liver disease using urinary metabolomics and the Ppara-null mouse. J Proteome Res (2010) 1.13
The role of mass spectrometry-based metabolomics in medical countermeasures against radiation. Mass Spectrom Rev (2010) 1.13
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The relative contribution of monoamine oxidase and cytochrome p450 isozymes to the metabolic deamination of the trace amine tryptamine. J Pharmacol Exp Ther (2003) 1.07
The metabolomics of (+/-)-arecoline 1-oxide in the mouse and its formation by human flavin-containing monooxygenases. Biochem Pharmacol (2006) 1.06
Metabolomics reveals attenuation of the SLC6A20 kidney transporter in nonhuman primate and mouse models of type 2 diabetes mellitus. J Biol Chem (2011) 1.06
Regenerative capacity of individual liver lobes in the microsurgical mouse model. Microsurgery (2006) 1.05
UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model. J Proteome Res (2011) 1.05
Operation time and body mass index are significant risk factors for surgical site infection in laparoscopic sigmoid resection: a multicenter study. Surg Endosc (2011) 1.05
A metabolomic perspective of melatonin metabolism in the mouse. Endocrinology (2008) 1.01
Human urinary metabolomic profile of PPARalpha induced fatty acid beta-oxidation. J Proteome Res (2009) 1.01
CD39 is incorporated into plasma microparticles where it maintains functional properties and impacts endothelial activation. Br J Haematol (2008) 1.00
Metabolomics reveals a novel vitamin E metabolite and attenuated vitamin E metabolism upon PXR activation. J Lipid Res (2009) 1.00
Xenobiotic metabolism: a view through the metabolometer. Chem Res Toxicol (2010) 0.96
Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Carcinogenesis (2006) 0.95
Comparative metabolism of cyclophosphamide and ifosfamide in the mouse using UPLC-ESI-QTOFMS-based metabolomics. Biochem Pharmacol (2010) 0.95
Elevated levels of placental growth factor represent an adaptive host response in sepsis. J Exp Med (2008) 0.94
A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4. Drug Metab Dispos (2008) 0.90
Role of pregnane X receptor in control of all-trans retinoic acid (ATRA) metabolism and its potential contribution to ATRA resistance. J Pharmacol Exp Ther (2007) 0.90
Control of steroid 21-oic acid synthesis by peroxisome proliferator-activated receptor alpha and role of the hypothalamic-pituitary-adrenal axis. J Biol Chem (2009) 0.90
Metabolomics reveals aging-associated attenuation of noninvasive radiation biomarkers in mice: potential role of polyamine catabolism and incoherent DNA damage-repair. J Proteome Res (2013) 0.89
Objective hypoesthesia and pain after transabdominal preperitoneal hernioplasty: a prospective, randomized study comparing tissue adhesive versus spiral tacks. Surg Endosc (2011) 0.89
A comprehensive understanding of thioTEPA metabolism in the mouse using UPLC-ESI-QTOFMS-based metabolomics. Biochem Pharmacol (2011) 0.89
Urinary metabolites and antioxidant products of exogenous melatonin in the mouse. J Pineal Res (2006) 0.87
The production and composition of rat sebum is unaffected by 3 Gy gamma radiation. Int J Radiat Biol (2010) 0.87
Urinary metabolomics in Fxr-null mice reveals activated adaptive metabolic pathways upon bile acid challenge. J Lipid Res (2009) 0.86
The glycine deportation system and its pharmacological consequences. Pharmacol Ther (2012) 0.85
Novel metabolites and roles for α-tocopherol in humans and mice discovered by mass spectrometry-based metabolomics. Am J Clin Nutr (2012) 0.84
Potential role of CYP2D6 in the central nervous system. Xenobiotica (2013) 0.84
Metabolomics and its potential in drug development. Biochem Pharmacol (2012) 0.84
Comparative aromatic hydroxylation and N-demethylation of MPTP neurotoxin and its analogs, N-methylated beta-carboline and isoquinoline alkaloids, by human cytochrome P450 2D6. Toxicol Appl Pharmacol (2006) 0.83
Loop ileostomy closure: comparison of cost effectiveness between suture and stapler. World J Surg (2010) 0.83
Molecular absorbent recirculating system for the treatment of acute liver failure in surgical patients. J Gastrointest Surg (2005) 0.83
3,4-Dehydrodebrisoquine, a novel debrisoquine metabolite formed from 4-hydroxydebrisoquine that affects the CYP2D6 metabolic ratio. Drug Metab Dispos (2006) 0.83
Intraperitoneal mesh implantation for fascial dehiscence and open abdomen. World J Surg (2012) 0.82
Dog bites man or man bites dog? The enigma of the amino acid conjugations. Biochem Pharmacol (2011) 0.82
Heightened NTPDase-1/CD39 expression and angiogenesis in radiation proctitis. Purinergic Signal (2009) 0.82
Metabolomics reveals the metabolic map of procainamide in humans and mice. Biochem Pharmacol (2012) 0.82
Tumor necrosis factor-related apoptosis-inducing ligand on NK cells protects from hepatic ischemia-reperfusion injury. Transplantation (2014) 0.82
Magnetic resonance imaging provides accurate and precise volume determination of the regenerating mouse liver. J Gastrointest Surg (2004) 0.82
Pinning down the polo-box domain. Chem Biol (2008) 0.81
Cerebral formation in situ of S-carboxymethylcysteine after ifosfamide administration to mice: a further clue to the mechanism of ifosfamide encephalopathy. Toxicol Lett (2005) 0.81
Laparoscopic incisional hernia repair is feasible and safe after liver transplantation. Surg Endosc (2009) 0.80
Metabolomic tissue signature in human non-alcoholic fatty liver disease identifies protective candidate metabolites. Liver Int (2014) 0.80
Fenofibrate metabolism in the cynomolgus monkey using ultraperformance liquid chromatography-quadrupole time-of-flight mass spectrometry-based metabolomics. Drug Metab Dispos (2009) 0.80
4-Hydroxylation of debrisoquine by human CYP1A1 and its inhibition by quinidine and quinine. J Pharmacol Exp Ther (2002) 0.79
Splanchnic vasoregulation after major abdominal surgery in pigs. World J Surg (2010) 0.79
Postoperative splanchnic blood flow redistribution in response to fluid challenges in the presence and absence of endotoxemia in a porcine model. Shock (2012) 0.78
Granulocyte colony-stimulating factor supports liver regeneration in a small-for-size liver remnant mouse model. J Gastrointest Surg (2007) 0.78
Analysis of N1-acetyl-N2-formyl-5-methoxykynuramine/N1-acetyl-5-methoxy-kynuramine formation from melatonin in mice. J Pineal Res (2010) 0.77
Implantation of prophylactic nonabsorbable intraperitoneal mesh in patients with peritonitis is safe and feasible. World J Surg (2013) 0.77
CYP2D6 polymorphism, tramadol pharmacokinetics and pupillary response. Eur J Clin Pharmacol (2005) 0.77
Additional surgical procedure is a risk factor for surgical site infections after laparoscopic cholecystectomy. Langenbecks Arch Surg (2014) 0.77
Racemates revisited: heterochiral assemblies and the example of DL-thalidomide. Xenobiotica (2011) 0.76
Cytochrome P450 regulation by α-tocopherol in Pxr-null and PXR-humanized mice. Drug Metab Dispos (2012) 0.76
Identification of 2-piperidone as a biomarker of CYP2E1 activity through metabolomic phenotyping. Toxicol Sci (2013) 0.76
Pharmacokinetics of tramadol is affected by MDR1 polymorphism C3435T. Eur J Clin Pharmacol (2007) 0.76
Effect of diabetes on outcomes in patients undergoing emergency cholecystectomy for acute cholecystitis. World J Surg (2013) 0.75
Interleukin-3 induces hepatocyte-specific metabolic activity in bone marrow-derived liver stem cells. J Gastrointest Surg (2005) 0.75
Painting the liver with lasers: the future of liver histology? Hepatology (2013) 0.75
Delayed Gastric Emptying after Pancreaticoduodenectomy: Analysis of Associated Risk Factors. Am Surg (2015) 0.75
Image of the month. Gallstone ileus. Arch Surg (2011) 0.75