Published in Lancet Neurol on September 03, 2012
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol (2013) 9.43
TDP-43 is a key player in the clinical features associated with Alzheimer's disease. Acta Neuropathol (2014) 1.47
Staging TDP-43 pathology in Alzheimer's disease. Acta Neuropathol (2013) 1.36
Clinicopathologic and 11C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer's disease spectrum. Brain (2015) 1.31
'Essential tremor' or 'the essential tremors': is this one disease or a family of diseases? Neuroepidemiology (2013) 1.10
Anatomical heterogeneity of Alzheimer disease: based on cortical thickness on MRIs. Neurology (2014) 0.99
FDG PET and MRI in logopenic primary progressive aphasia versus dementia of the Alzheimer's type. PLoS One (2013) 0.96
A data-driven model of biomarker changes in sporadic Alzheimer's disease. Brain (2014) 0.96
Quantitative neurofibrillary tangle density and brain volumetric MRI analyses in Alzheimer's disease presenting as logopenic progressive aphasia. Brain Lang (2013) 0.94
Voxel-based Morphometry of Brain MRI in Normal Aging and Alzheimer's Disease. Aging Dis (2012) 0.91
HSV-1 and Alzheimer's disease: more than a hypothesis. Front Pharmacol (2014) 0.91
Brain metabolic maps in Mild Cognitive Impairment predict heterogeneity of progression to dementia. Neuroimage Clin (2014) 0.91
Neural correlates of spatial navigation changes in mild cognitive impairment and Alzheimer's disease. Front Behav Neurosci (2014) 0.89
Magnetic resonance spectroscopy in Alzheimer's disease. Neuropsychiatr Dis Treat (2013) 0.86
The emerging agenda of stratified medicine in neurology. Nat Rev Neurol (2013) 0.85
Medial temporal atrophy in early and late-onset Alzheimer's disease. Neurobiol Aging (2014) 0.85
Application of a MRI based index to longitudinal atrophy change in Alzheimer disease, mild cognitive impairment and healthy older individuals in the AddNeuroMed cohort. Front Aging Neurosci (2014) 0.84
TAR DNA-binding protein 43 and pathological subtype of Alzheimer's disease impact clinical features. Ann Neurol (2015) 0.82
Neuropathologic correlates of regional brain volumes in a community cohort of older adults. Neurobiol Aging (2015) 0.82
[(18) F]AV-1451 tau positron emission tomography in progressive supranuclear palsy. Mov Disord (2016) 0.80
Prediction of Alzheimer's disease pathophysiology based on cortical thickness patterns. Alzheimers Dement (Amst) (2015) 0.80
Relationship between hippocampal atrophy and neuropathology markers: a 7T MRI validation study of the EADC-ADNI Harmonized Hippocampal Segmentation Protocol. Alzheimers Dement (2015) 0.80
HYDRA: Revealing heterogeneity of imaging and genetic patterns through a multiple max-margin discriminative analysis framework. Neuroimage (2016) 0.79
Mapping the Progression of Atrophy in Early- and Late-Onset Alzheimer's Disease. J Alzheimers Dis (2015) 0.79
Bayesian model reveals latent atrophy factors with dissociable cognitive trajectories in Alzheimer's disease. Proc Natl Acad Sci U S A (2016) 0.78
Heterogeneity of Regional Brain Atrophy Patterns Associated with Distinct Progression Rates in Alzheimer's Disease. PLoS One (2015) 0.78
Clinical stratification of subtypes of Alzheimer's disease. Lancet Neurol (2012) 0.78
Quantitative neuropathological assessment to investigate cerebral multi-morbidity. Alzheimers Res Ther (2014) 0.77
Graph theoretic analysis of structural connectivity across the spectrum of Alzheimer's disease: The importance of graph creation methods. Neuroimage Clin (2015) 0.76
Connectivity Disruption, Atrophy, and Hypometabolism within Posterior Cingulate Networks in Alzheimer's Disease. Front Neurosci (2016) 0.76
Hippocampal volumes predict risk of dementia with Lewy bodies in mild cognitive impairment. Neurology (2016) 0.75
Robust Identification of Alzheimer's Disease subtypes based on cortical atrophy patterns. Sci Rep (2017) 0.75
Early-onset Alzheimer's disease versus frontotemporal dementia: resolution with genetic diagnoses? Neurocase (2015) 0.75
New scoring methodology improves the sensitivity of the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog) in clinical trials. Alzheimers Res Ther (2015) 0.75
Age and neurodegeneration imaging biomarkers in persons with Alzheimer disease dementia. Neurology (2016) 0.75
18F-FDG PET in Posterior Cortical Atrophy and Dementia with Lewy Bodies. J Nucl Med (2016) 0.75
Distinct subtypes of Alzheimer's disease based on patterns of brain atrophy: longitudinal trajectories and clinical applications. Sci Rep (2017) 0.75
Magnetic Resonance Imaging to Detect Early Molecular and Cellular Changes in Alzheimer's Disease. Front Aging Neurosci (2016) 0.75
Alzheimer's disease: The influence of age on clinical heterogeneity through the human brain connectome. Alzheimers Dement (Amst) (2016) 0.75
Quantitative T2 mapping of white matter: applications for ageing and cognitive decline. Phys Med Biol (2016) 0.75
Multi-contrast submillimetric 3 Tesla hippocampal subfield segmentation protocol and dataset. Sci Data (2015) 0.75
Neuroimaging Feature Terminology: A Controlled Terminology for the Annotation of Brain Imaging Features. J Alzheimers Dis (2017) 0.75
A review on neuroimaging-based classification studies and associated feature extraction methods for Alzheimer's disease and its prodromal stages. Neuroimage (2017) 0.75
Disentangling Disease Heterogeneity with Max-Margin Multiple Hyperplane Classifier. Med Image Comput Comput Assist Interv (2015) 0.75
Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage (2002) 49.90
Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (1991) 49.03
Voxel-based morphometry--the methods. Neuroimage (2000) 34.79
Unified segmentation. Neuroimage (2005) 30.20
No adjustments are needed for multiple comparisons. Epidemiology (1990) 23.80
A nonparametric method for automatic correction of intensity nonuniformity in MRI data. IEEE Trans Med Imaging (1998) 23.54
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology (1991) 23.01
What's wrong with Bonferroni adjustments. BMJ (1998) 19.89
Consensus recommendations for the postmortem diagnosis of Alzheimer disease from the National Institute on Aging and the Reagan Institute Working Group on diagnostic criteria for the neuropathological assessment of Alzheimer disease. J Neuropathol Exp Neurol (1997) 6.12
Neuropathology of cognitively normal elderly. J Neuropathol Exp Neurol (2003) 5.17
Antemortem MRI findings correlate with hippocampal neuropathology in typical aging and dementia. Neurology (2002) 4.50
Alzheimer's disease diagnosis in individual subjects using structural MR images: validation studies. Neuroimage (2007) 4.41
Focal cortical presentations of Alzheimer's disease. Brain (2007) 4.07
Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia. Ann Neurol (2008) 3.99
Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study. Lancet Neurol (2011) 3.63
Atypical and typical presentations of Alzheimer's disease: a clinical, neuropsychological, neuroimaging and pathological study of 13 cases. Brain (2000) 3.14
Hippocampal volume as an index of Alzheimer neuropathology: findings from the Nun Study. Neurology (2002) 2.87
Mayo Clinic Alzheimer's Disease Patient Registry. Aging (Milano) (1990) 2.77
MRI correlates of neurofibrillary tangle pathology at autopsy: a voxel-based morphometry study. Neurology (2008) 2.69
Clinical syndromes associated with posterior atrophy: early age at onset AD spectrum. Neurology (2009) 2.46
Progressive aphasia secondary to Alzheimer disease vs FTLD pathology. Neurology (2008) 2.45
Voxel-based morphometric comparison between early- and late-onset mild Alzheimer's disease and assessment of diagnostic performance of z score images. AJNR Am J Neuroradiol (2005) 1.97
Correlations between antemortem hippocampal volume and postmortem neuropathology in AD subjects. Alzheimer Dis Assoc Disord (2004) 1.91
Structural correlates of early and late onset Alzheimer's disease: voxel based morphometric study. J Neurol Neurosurg Psychiatry (2005) 1.52
Temporoparietal atrophy: a marker of AD pathology independent of clinical diagnosis. Neurobiol Aging (2009) 1.46
ROC analysis with multiple classes and multiple tests: methodology and its application in microarray studies. Biostatistics (2008) 1.35
Reduced cortical thickness in the posterior cingulate gyrus is characteristic of both typical and atypical Alzheimer's disease. J Alzheimers Dis (2010) 1.23
Cognitive differences between early- and late-onset Alzheimer's disease. Am J Alzheimers Dis Other Demen (2007) 1.12
The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 24.26
Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 24.02
The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 21.80
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron (2011) 20.15
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol (2010) 19.42
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects. Ann Neurol (2009) 14.42
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron (2004) 14.35
A roadmap for the prevention of dementia II: Leon Thal Symposium 2008. Alzheimers Dement (2009) 10.21
Mild cognitive impairment. Lancet (2006) 10.21
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke (2011) 10.11
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. Brain (2011) 9.90
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat Genet (2007) 9.80
11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment. Brain (2008) 9.64
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol (2013) 9.43
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathol (2007) 8.10
Ways toward an early diagnosis in Alzheimer's disease: the Alzheimer's Disease Neuroimaging Initiative (ADNI). Alzheimers Dement (2005) 7.90
The Alzheimer's disease neuroimaging initiative. Neuroimaging Clin N Am (2005) 7.26
Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease. Brain (2009) 7.20
Clinical diagnostic criteria for dementia associated with Parkinson's disease. Mov Disord (2007) 6.92
A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica. Brain (2002) 6.85
Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 6.84
Automatic classification of MR scans in Alzheimer's disease. Brain (2008) 6.71
A roadmap for the prevention of dementia: the inaugural Leon Thal Symposium. Alzheimers Dement (2008) 6.39
Neuropathologic features of amnestic mild cognitive impairment. Arch Neurol (2006) 6.20
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach. Acta Neuropathol (2011) 6.00
TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease. Ann Neurol (2007) 5.98
The Mayo Clinic Study of Aging: design and sampling, participation, baseline measures and sample characteristics. Neuroepidemiology (2008) 5.94
Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS. Neuron (2013) 5.91
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52
Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain (2005) 5.29
Pathological gambling caused by drugs used to treat Parkinson disease. Arch Neurol (2005) 5.19
Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines. Mov Disord (2012) 5.12
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimers Dement (2012) 5.10
Protective variant for hippocampal atrophy identified by whole exome sequencing. Ann Neurol (2015) 5.10
The NIH Cognitive and Emotional Health Project. Report of the Critical Evaluation Study Committee. Alzheimers Dement (2006) 5.05
Mild cognitive impairment: ten years later. Arch Neurol (2009) 5.02
Developing a national strategy to prevent dementia: Leon Thal Symposium 2009. Alzheimers Dement (2010) 4.85
Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathol (2009) 4.73
Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations. Acta Neuropathol (2008) 4.73
Primary central nervous system vasculitis: analysis of 101 patients. Ann Neurol (2007) 4.68
Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials. Arch Neurol (2004) 4.66
The clinical use of structural MRI in Alzheimer disease. Nat Rev Neurol (2010) 4.59
Neuropathologic outcome of mild cognitive impairment following progression to clinical dementia. Arch Neurol (2006) 4.56
Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis. Brain (2007) 4.50
Alzheimer's disease diagnosis in individual subjects using structural MR images: validation studies. Neuroimage (2007) 4.41
Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease. Brain (2010) 4.39
Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease. Neurobiol Aging (2009) 4.36
An operational approach to National Institute on Aging-Alzheimer's Association criteria for preclinical Alzheimer disease. Ann Neurol (2012) 4.36