Published in Mol Pharmacol on September 05, 2012
Functional role of post-translational modifications of Sp1 in tumorigenesis. J Biomed Sci (2012) 1.09
Sp1-mediated microRNA-182 expression regulates lung cancer progression. Oncotarget (2014) 1.07
Regulation of transcription factor activity by interconnected post-translational modifications. Trends Pharmacol Sci (2013) 0.95
Plant terpenes: defense responses, phylogenetic analysis, regulation and clinical applications. 3 Biotech (2014) 0.93
Inhibition of Sp1 functions by its sequestration into PML nuclear bodies. PLoS One (2014) 0.82
Activation of AKR1C1/ERβ induces apoptosis by downregulation of c-FLIP in prostate cancer cells: A prospective therapeutic opportunity. Oncotarget (2015) 0.82
Modulation of specificity protein 1 by mithramycin A as a novel therapeutic strategy for cervical cancer. Sci Rep (2014) 0.78
A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy. Oncotarget (2015) 0.77
Aberrant sumoylation signaling evoked by reactive oxygen species impairs protective function of Prdx6 by destabilization and repression of its transcription. FEBS J (2014) 0.77
The efficacy of betulinic acid in triple-negative breast cancer. SAGE Open Med (2014) 0.75
Lupane-type triterpenes and their anti-cancer activities against most common malignant tumors: A review. EXCLI J (2016) 0.75
MicroRNA-149 targets specificity protein 1 to suppress human tongue squamous cell carcinoma cell proliferation and motility. Oncol Lett (2016) 0.75
A piperazidine derivative of 23-hydroxy betulinic acid induces a mitochondria-derived ROS burst to trigger apoptotic cell death in hepatocellular carcinoma cells. J Exp Clin Cancer Res (2016) 0.75
Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations. J Clin Oncol (2013) 11.68
AZD9291 in EGFR inhibitor-resistant non-small-cell lung cancer. N Engl J Med (2015) 7.11
Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial. Lancet Oncol (2012) 5.82
Afatinib for patients with lung adenocarcinoma and epidermal growth factor receptor mutations (LUX-Lung 2): a phase 2 trial. Lancet Oncol (2012) 2.52
The human serum proteome: display of nearly 3700 chromatographically separated protein spots on two-dimensional electrophoresis gels and identification of 325 distinct proteins. Proteomics (2003) 2.41
Integrated next-generation sequencing of 16S rDNA and metaproteomics differentiate the healthy urine microbiome from asymptomatic bacteriuria in neuropathic bladder associated with spinal cord injury. J Transl Med (2012) 2.37
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet (2012) 2.26
Multi-component immunoaffinity subtraction chromatography: an innovative step towards a comprehensive survey of the human plasma proteome. Proteomics (2003) 2.04
The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. PLoS Genet (2010) 1.90
Endoplasmic reticulum stress stimulates the expression of cyclooxygenase-2 through activation of NF-kappaB and pp38 mitogen-activated protein kinase. J Biol Chem (2004) 1.86
Prognostic value of whole-body total lesion glycolysis at pretreatment FDG PET/CT in non-small cell lung cancer. Radiology (2012) 1.75
Bevacizumab with erlotinib as first-line therapy in Asian patients with advanced hepatocellular carcinoma: a multicenter phase II study. Oncology (2013) 1.70
Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression. Nucleic Acids Res (2008) 1.66
Studies of chi(2)/chi(3) tensors in submicron-scaled bio-tissues by polarization harmonics optical microscopy. Biophys J (2004) 1.65
Identification of calcineurin as a key signal in the extinction of fear memory. J Neurosci (2003) 1.64
The APEX Quantitative Proteomics Tool: generating protein quantitation estimates from LC-MS/MS proteomics results. BMC Bioinformatics (2008) 1.54
Bone marrow that is positive for Epstein-Barr virus encoded RNA-1 by in situ hybridization is related with a poor prognosis in patients with extranodal natural killer/T-cell lymphoma, nasal type. Haematologica (2005) 1.52
Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells. J Biol Chem (2011) 1.52
Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients. Clin Cancer Res (2005) 1.47
Proteomic profiling of cell envelope-associated proteins from Staphylococcus aureus. Proteomics (2006) 1.42
Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein beta and delta in lipopolysaccharide-induced gene activation of IL-10 in mouse macrophages. J Immunol (2003) 1.41
Sp1 deacetylation induced by phorbol ester recruits p300 to activate 12(S)-lipoxygenase gene transcription. Mol Cell Biol (2006) 1.32
Phosphorylation by c-Jun NH2-terminal kinase 1 regulates the stability of transcription factor Sp1 during mitosis. Mol Biol Cell (2008) 1.31
Sumoylation of specificity protein 1 augments its degradation by changing the localization and increasing the specificity protein 1 proteolytic process. J Mol Biol (2008) 1.26
Lipopolysaccharide-induced transcriptional activation of interleukin-10 is mediated by MAPK- and NF-kappaB-induced CCAAT/enhancer-binding protein delta in mouse macrophages. Cell Signal (2006) 1.24
A novel method of isolation, preservation, and expansion of human corneal endothelial cells. Invest Ophthalmol Vis Sci (2007) 1.24
In vivo developmental biology study using noninvasive multi-harmonic generation microscopy. Opt Express (2003) 1.23
Epigenetic silencing of CCAAT/enhancer-binding protein delta activity by YY1/polycomb group/DNA methyltransferase complex. J Biol Chem (2008) 1.21
Expression of S100A4 and Met: potential predictors for metastasis and survival in early-stage breast cancer. Oncology (2004) 1.21
Isolation and expansion of human limbal stromal niche cells. Invest Ophthalmol Vis Sci (2012) 1.20
Higher harmonic generation microscopy for developmental biology. J Struct Biol (2004) 1.20
Overexpression of Sp1 leads to p53-dependent apoptosis in cancer cells. Int J Cancer (2009) 1.19
Temperature and growth phase influence the outer-membrane proteome and the expression of a type VI secretion system in Yersinia pestis. Microbiology (2009) 1.19
Nuclear export and import of human hepatitis B virus capsid protein and particles. PLoS Pathog (2010) 1.18
Comparative proteomic analysis of Staphylococcus aureus strains with differences in resistance to the cell wall-targeting antibiotic vancomycin. Proteomics (2006) 1.16
A randomized, double-blind, parallel, comparative study to evaluate the efficacy and safety of ramosetron plus dexamethasone injection for the prevention of acute chemotherapy-induced nausea and vomiting. Jpn J Clin Oncol (2009) 1.16
Sequential caspase-2 and caspase-8 activation upstream of mitochondria during ceramideand etoposide-induced apoptosis. J Biol Chem (2004) 1.15
Targeted Paclitaxel by conjugation to iron oxide and gold nanoparticles. J Am Chem Soc (2009) 1.13
Human amniotic epithelial cells as novel feeder layers for promoting ex vivo expansion of limbal epithelial progenitor cells. Stem Cells (2007) 1.13
Predictive and prognostic value of human copper transporter 1 (hCtr1) in patients with stage III non-small-cell lung cancer receiving first-line platinum-based doublet chemotherapy. Lung Cancer (2011) 1.12
Characterization and comparison of intercellular adherent junctions expressed by human corneal endothelial cells in vivo and in vitro. Invest Ophthalmol Vis Sci (2008) 1.12
A polymorphism in the APE1 gene promoter is associated with lung cancer risk. Cancer Epidemiol Biomarkers Prev (2009) 1.11
Induction of disease-associated keratin 16 gene expression by epidermal growth factor is regulated through cooperation of transcription factors Sp1 and c-Jun. J Biol Chem (2003) 1.09
Hormone replacement therapy and lung cancer risk in Chinese. Cancer (2007) 1.09
A proteogenomic update to Yersinia: enhancing genome annotation. BMC Genomics (2010) 1.09
In vivo harmonic generation biopsy of human skin. J Biomed Opt (2010) 1.09
Functional role of post-translational modifications of Sp1 in tumorigenesis. J Biomed Sci (2012) 1.09
Involvement of store-operated calcium signaling in EGF-mediated COX-2 gene activation in cancer cells. Cell Signal (2011) 1.09
Functional role of NF-IL6beta and its sumoylation and acetylation modifications in promoter activation of cyclooxygenase 2 gene. Nucleic Acids Res (2006) 1.08
Limbal epithelial stem/progenitor cells attract stromal niche cells by SDF-1/CXCR4 signaling to prevent differentiation. Stem Cells (2011) 1.08
RNA-binding protein HuR interacts with thrombomodulin 5'untranslated region and represses internal ribosome entry site-mediated translation under IL-1 beta treatment. Mol Biol Cell (2008) 1.07
Sp1-mediated microRNA-182 expression regulates lung cancer progression. Oncotarget (2014) 1.07
The balance between adipogenesis and osteogenesis in bone regeneration by platelet-rich plasma for age-related osteoporosis. Biomaterials (2011) 1.06
Hypoxia and metabolic phenotypes during breast carcinogenesis: expression of HIF-1alpha, GLUT1, and CAIX. Virchows Arch (2010) 1.06
Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription-3 activity independently of the liver kinase B1-AMP-activated protein kinase pathway. Am J Respir Cell Mol Biol (2013) 1.06
An open-label, single-arm, phase 2 trial of the Polo-like kinase inhibitor volasertib (BI 6727) in patients with locally advanced or metastatic urothelial cancer. Cancer (2013) 1.05
Biochemical characterization and function of complexes formed by hyaluronan and the heavy chains of inter-alpha-inhibitor (HC*HA) purified from extracts of human amniotic membrane. J Biol Chem (2009) 1.04
ERK2-mediated C-terminal serine phosphorylation of p300 is vital to the regulation of epidermal growth factor-induced keratin 16 gene expression. J Biol Chem (2007) 1.04
Vinca alkaloids cause aberrant ROS-mediated JNK activation, Mcl-1 downregulation, DNA damage, mitochondrial dysfunction, and apoptosis in lung adenocarcinoma cells. Biochem Pharmacol (2012) 1.03
Nuclear p120 catenin unlocks mitotic block of contact-inhibited human corneal endothelial monolayers without disrupting adherent junctions. J Cell Sci (2012) 1.03
Wnt signaling induces epithelial-mesenchymal transition with proliferation in ARPE-19 cells upon loss of contact inhibition. Lab Invest (2012) 1.03
Glycogen synthase kinase 3 alpha and 3 beta have distinct functions during cardiogenesis of zebrafish embryo. BMC Dev Biol (2007) 1.02
Mesenchymal stem cells derived from human limbal niche cells. Invest Ophthalmol Vis Sci (2012) 1.02
Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST. J Biol Chem (2006) 1.01
Interplay of posttranslational modifications in Sp1 mediates Sp1 stability during cell cycle progression. J Mol Biol (2011) 1.01
Characterizing the dynamic nature of the Yersinia pestis periplasmic proteome in response to nutrient exhaustion and temperature change. Proteomics (2008) 1.01
Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells. PLoS One (2011) 1.00
Angiogenetic biomarkers in non-small cell lung cancer with malignant pleural effusion: correlations with patient survival and pleural effusion control. Lung Cancer (2009) 1.00
Safety and Efficacy of Buparlisib (BKM120) in Patients with PI3K Pathway-Activated Non-Small Cell Lung Cancer: Results from the Phase II BASALT-1 Study. J Thorac Oncol (2015) 0.99
Suppression of activation and induction of apoptosis in RAW264.7 cells by amniotic membrane extract. Invest Ophthalmol Vis Sci (2008) 0.99
ZBRK1 acts as a metastatic suppressor by directly regulating MMP9 in cervical cancer. Cancer Res (2009) 0.99
Distinct regulation of cyclooxygenase-2 by interleukin-1beta in normal and endometriotic stromal cells. J Clin Endocrinol Metab (2004) 0.98
Increased expression of nitric oxide synthase and cyclooxygenase-2 is associated with poor survival in cervical cancer treated with radiotherapy. Int J Radiat Oncol Biol Phys (2005) 0.98
Glycogen synthase kinase-3 and Omi/HtrA2 induce annexin A2 cleavage followed by cell cycle inhibition and apoptosis. Mol Biol Cell (2009) 0.97
Angiogenesis potential of human limbal stromal niche cells. Invest Ophthalmol Vis Sci (2012) 0.97
HDAC1/HDAC3 modulates PPARG2 transcription through the sumoylated CEBPD in hepatic lipogenesis. Biochim Biophys Acta (2008) 0.97
Epidermal growth factor increases the interaction between nucleolin and heterogeneous nuclear ribonucleoprotein K/poly(C) binding protein 1 complex to regulate the gastrin mRNA turnover. Mol Biol Cell (2007) 0.97
Hypoxia-inducible factor-1alpha correlates with MET and metastasis in node-negative breast cancer. Breast Cancer Res Treat (2006) 0.96
Selective inhibition of early--but not late--expressed HIF-1α is neuroprotective in rats after focal ischemic brain damage. Brain Pathol (2010) 0.96
A phase II trial of gemcitabine in the treatment of advanced bile duct and periampullary carcinomas. Chemotherapy (2003) 0.96
Genome-wide association study of genetic predictors of overall survival for non-small cell lung cancer in never smokers. Cancer Res (2013) 0.96
Noninvasive saliva-based EGFR gene mutation detection in patients with lung cancer. Am J Respir Crit Care Med (2014) 0.95
Air exposure induced squamous metaplasia of human limbal epithelium. Invest Ophthalmol Vis Sci (2008) 0.95
Association of an EGFR intron 1 SNP with never-smoking female lung adenocarcinoma patients. Lung Cancer (2008) 0.95
Rubrobacter taiwanensis sp. nov., a novel thermophilic, radiation-resistant species isolated from hot springs. Int J Syst Evol Microbiol (2004) 0.95
The Shigella dysenteriae serotype 1 proteome, profiled in the host intestinal environment, reveals major metabolic modifications and increased expression of invasive proteins. Proteomics (2009) 0.94
In vivo optical virtual biopsy of human oral mucosa with harmonic generation microscopy. Biomed Opt Express (2011) 0.94
Nucleolin regulates c-Jun/Sp1-dependent transcriptional activation of cPLA2alpha in phorbol ester-treated non-small cell lung cancer A549 cells. Nucleic Acids Res (2007) 0.93
Heat shock protein 90 is important for Sp1 stability during mitosis. J Mol Biol (2009) 0.93