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1
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Aneuploidy acts both oncogenically and as a tumor suppressor.
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Cancer Cell
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2006
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6.37
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2
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Comparative isoschizomer profiling of cytosine methylation: the HELP assay.
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Genome Res
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2006
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5.99
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3
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PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab.
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Cancer Res
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2008
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3.98
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4
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Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibition.
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Mol Biol Cell
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2005
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2.36
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5
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KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors.
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Cell
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2013
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2.34
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6
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Of mice and MEN1: Insulinomas in a conditional mouse knockout.
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Mol Cell Biol
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2003
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2.12
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7
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Effectiveness of gene expression profiling for response prediction of rectal adenocarcinomas to preoperative chemoradiotherapy.
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J Clin Oncol
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2005
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2.07
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8
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Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations.
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Blood
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2012
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1.98
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9
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STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation.
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Proc Natl Acad Sci U S A
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2002
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1.69
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10
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Genetic dosage compensation in a family with velo-cardio-facial/DiGeorge/22q11.2 deletion syndrome.
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Am J Med Genet A
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2011
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1.54
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11
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Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer.
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Oncogene
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2002
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1.42
|
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12
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Overexpression of IL-1 receptor accessory protein in stem and progenitor cells and outcome correlation in AML and MDS.
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Blood
|
2012
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1.36
|
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13
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Septin roles in tumorigenesis.
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Biol Chem
|
2011
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1.24
|
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14
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Hormone-induced chromosomal instability in p53-null mammary epithelium.
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Cancer Res
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2004
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1.21
|
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15
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Loss of polycystin-1 causes centrosome amplification and genomic instability.
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Hum Mol Genet
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2008
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1.20
|
|
16
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Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors.
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Oncotarget
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2011
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1.19
|
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17
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Loss of CCAAT/enhancer binding protein delta promotes chromosomal instability.
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Oncogene
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2004
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1.16
|
|
18
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Septin 9 isoform expression, localization and epigenetic changes during human and mouse breast cancer progression.
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Breast Cancer Res
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2011
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1.13
|
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19
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SMC1 involvement in fragile site expression.
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Hum Mol Genet
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2005
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1.11
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20
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Haploinsufficiency of Anx7 tumor suppressor gene and consequent genomic instability promotes tumorigenesis in the Anx7(+/-) mouse.
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Proc Natl Acad Sci U S A
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2003
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1.01
|
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21
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Inhibition of BUB1 results in genomic instability and anchorage-independent growth of normal human fibroblasts.
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Cancer Res
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2003
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1.00
|
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22
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Chromosome-specific accumulation of aneuploidy in the aging mouse brain.
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Hum Mol Genet
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2012
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1.00
|
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23
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Two replication fork maintenance pathways fuse inverted repeats to rearrange chromosomes.
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Nature
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2013
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0.99
|
|
24
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Cell fusion is a physiological process in mouse liver.
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Hepatology
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2008
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0.98
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25
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An A13 repeat within the 3'-untranslated region of epidermal growth factor receptor (EGFR) is frequently mutated in microsatellite instability colon cancers and is associated with increased EGFR expression.
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Cancer Res
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2009
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0.97
|
|
26
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Chromosomal aneuploidy in the aging brain.
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Mech Ageing Dev
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2011
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0.95
|
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27
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RAD51 mutants cause replication defects and chromosomal instability.
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Mol Cell Biol
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2012
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0.91
|
|
28
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Therapeutically targeting cyclin D1 in primary tumors arising from loss of Ini1.
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Proc Natl Acad Sci U S A
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2010
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0.90
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29
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Atm heterozygosity cooperates with loss of Brca1 to increase the severity of mammary gland cancer and reduce ductal branching.
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Cancer Res
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2005
|
0.89
|
|
30
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E6 and E7 oncoproteins induce distinct patterns of chromosomal aneuploidy in skin tumors from transgenic mice.
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Cancer Res
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2004
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0.89
|
|
31
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Dendritic cell-mediated in vivo bone resorption.
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J Immunol
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2010
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0.87
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32
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Silencing of the Il2 gene transcription is regulated by epigenetic changes in anergic T cells.
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Eur J Immunol
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2012
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0.87
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33
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Prognostic and predictive value of 16p12.1 and 16q22.1 copy number changes in human breast cancer.
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Cancer Genet Cytogenet
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2010
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0.85
|
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34
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Molecular cytogenetics of mouse models of breast cancer.
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Breast Dis
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2004
|
0.85
|
|
35
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A mammary-specific, long-range deletion on mouse chromosome 11 accelerates Brca1-associated mammary tumorigenesis.
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Neoplasia
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2008
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0.84
|
|
36
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Spectral karyotyping in cancer cytogenetics.
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Methods Mol Med
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2002
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0.84
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37
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Septin 9 amplification and isoform-specific expression in peritumoral and tumor breast tissue.
|
Biol Chem
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2014
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0.82
|
|
38
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Recapitulation of the Roberts syndrome cellular phenotype by inhibition of INCENP, ZWINT-1 and ZW10 genes.
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Gene
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2004
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0.81
|
|
39
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DNA methylation changes in murine breast adenocarcinomas allow the identification of candidate genes for human breast carcinogenesis.
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Mamm Genome
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2011
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0.80
|
|
40
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Msh6 protects mature B cells from lymphoma by preserving genomic stability.
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Am J Pathol
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2010
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0.80
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41
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Toxicological and biochemical response to azinphos-methyl in Cydia pomonella L. (Lepidoptera: Tortricidae) among orchards from the Argentinian Patagonia.
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Pest Manag Sci
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2008
|
0.80
|
|
42
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Tissue-specific sensitivity to AID expression in transgenic mouse models.
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Gene
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2006
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0.80
|
|
43
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Single-cell analysis of ploidy and centrosomes underscores the peculiarity of normal hepatocytes.
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PLoS One
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2011
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0.79
|
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44
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Highlight: the 5th International Workshop on Septin Biology.
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Biol Chem
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2014
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0.78
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45
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Analysis of 41 cancer cell lines reveals excessive allelic loss and novel mutations in the SIRT1 gene.
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Cell Cycle
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2012
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0.78
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46
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Seeking truth on Monte Verita. Workshop on the molecular biology and biochemistry of septins and septin function.
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EMBO Rep
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2007
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0.78
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47
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Four-color FISH for the detection of low-level aneuploidy in interphase cells.
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Methods Mol Biol
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2014
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0.78
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48
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Advanced molecular cytogenetics in human and mouse.
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Expert Rev Mol Diagn
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2004
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0.78
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49
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Inhibition of Plk1 and Cyclin B1 expression results in panobinostat-induced G₂ delay and mitotic defects.
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Sci Rep
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2013
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0.77
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50
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Translating the TCGA breast cancer results into clinical practice: searching for therapeutic clues.
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Oncology (Williston Park)
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2013
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0.77
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51
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SMC1 inhibition results in FRA3B expression but has no effect on its delayed replication.
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Mutat Res
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2006
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0.76
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52
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A syndrome of holoprosencephaly, recurrent infections, and monocytosis.
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Am J Med Genet A
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2006
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0.75
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