Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Biological, clinical and population relevance of 95 loci for blood lipids.
|
Nature
|
2010
|
28.21
|
2
|
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
|
Nat Genet
|
2008
|
12.32
|
3
|
New loci associated with kidney function and chronic kidney disease.
|
Nat Genet
|
2010
|
5.58
|
4
|
Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts.
|
Kidney Int
|
2011
|
5.25
|
5
|
Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum.
|
PLoS Genet
|
2008
|
5.23
|
6
|
A genome-wide perspective of genetic variation in human metabolism.
|
Nat Genet
|
2009
|
5.00
|
7
|
SLC2A9 influences uric acid concentrations with pronounced sex-specific effects.
|
Nat Genet
|
2008
|
4.67
|
8
|
Fibroblast growth factor 23 (FGF23) predicts progression of chronic kidney disease: the Mild to Moderate Kidney Disease (MMKD) Study.
|
J Am Soc Nephrol
|
2007
|
4.59
|
9
|
Telomere length and risk of incident cancer and cancer mortality.
|
JAMA
|
2010
|
3.55
|
10
|
On the replication of genetic associations: timing can be everything!
|
Am J Hum Genet
|
2008
|
3.32
|
11
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
12
|
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
|
Nat Genet
|
2011
|
3.03
|
13
|
HaploGrep: a fast and reliable algorithm for automatic classification of mitochondrial DNA haplogroups.
|
Hum Mutat
|
2010
|
3.02
|
14
|
Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus.
|
Nat Med
|
2013
|
2.93
|
15
|
Influences on the reduction of relative telomere length over 10 years in the population-based Bruneck Study: introduction of a well-controlled high-throughput assay.
|
Int J Epidemiol
|
2009
|
2.87
|
16
|
Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting.
|
PLoS One
|
2010
|
2.84
|
17
|
Serum iPTH, calcium and phosphate, and the risk of mortality in a European haemodialysis population.
|
Nephrol Dial Transplant
|
2010
|
2.70
|
18
|
CUBN is a gene locus for albuminuria.
|
J Am Soc Nephrol
|
2011
|
2.70
|
19
|
Discovery of sexual dimorphisms in metabolic and genetic biomarkers.
|
PLoS Genet
|
2011
|
2.68
|
20
|
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus.
|
Nature
|
2011
|
2.59
|
21
|
Association of genetic variation on chromosome 9p21 with susceptibility and progression of atherosclerosis: a population-based, prospective study.
|
J Am Coll Cardiol
|
2008
|
2.56
|
22
|
Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study.
|
PLoS One
|
2008
|
2.37
|
23
|
Associations of estimated glomerular filtration rate and albuminuria with mortality and renal failure by sex: a meta-analysis.
|
BMJ
|
2013
|
2.24
|
24
|
Genetic architecture of the APM1 gene and its influence on adiponectin plasma levels and parameters of the metabolic syndrome in 1,727 healthy Caucasians.
|
Diabetes
|
2006
|
2.23
|
25
|
Association between the UGT1A1*28 allele, bilirubin levels, and coronary heart disease in the Framingham Heart Study.
|
Circulation
|
2006
|
2.18
|
26
|
Asymmetric dimethylarginine and progression of chronic kidney disease: the mild to moderate kidney disease study.
|
J Am Soc Nephrol
|
2005
|
2.00
|
27
|
Serum creatinine, cystatin C, and beta-trace protein in diagnostic staging and predicting progression of primary nondiabetic chronic kidney disease.
|
Clin Chem
|
2010
|
1.95
|
28
|
A genome-wide association study of metabolic traits in human urine.
|
Nat Genet
|
2011
|
1.84
|
29
|
Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions.
|
Circ Cardiovasc Genet
|
2008
|
1.82
|
30
|
Association of ankle-brachial index and plaques in the carotid and femoral arteries with cardiovascular events and total mortality in a population-based study with 13 years of follow-up.
|
Eur Heart J
|
2006
|
1.82
|
31
|
Cellular aging reflected by leukocyte telomere length predicts advanced atherosclerosis and cardiovascular disease risk.
|
Arterioscler Thromb Vasc Biol
|
2010
|
1.81
|
32
|
Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease.
|
Atherosclerosis
|
2009
|
1.80
|
33
|
Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck study.
|
Arterioscler Thromb Vasc Biol
|
2007
|
1.79
|
34
|
Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals.
|
Atherosclerosis
|
2009
|
1.78
|
35
|
Renal insulin resistance syndrome, adiponectin and cardiovascular events in patients with kidney disease: the mild and moderate kidney disease study.
|
J Am Soc Nephrol
|
2005
|
1.74
|
36
|
Predictive performance of renal function equations for patients with chronic kidney disease and normal serum creatinine levels.
|
J Am Soc Nephrol
|
2002
|
1.70
|
37
|
Genome-wide association and functional follow-up reveals new loci for kidney function.
|
PLoS Genet
|
2012
|
1.68
|
38
|
Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD.
|
PLoS Genet
|
2011
|
1.68
|
39
|
Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients.
|
Am J Hum Genet
|
2010
|
1.67
|
40
|
Differences between human plasma and serum metabolite profiles.
|
PLoS One
|
2011
|
1.61
|
41
|
Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI.
|
Diabetes Care
|
2008
|
1.58
|
42
|
Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer.
|
Cancer Epidemiol Biomarkers Prev
|
2008
|
1.58
|
43
|
Lipoprotein metabolism and lipid management in chronic kidney disease.
|
J Am Soc Nephrol
|
2007
|
1.53
|
44
|
Re-evaluation of the penicillamine challenge test in the diagnosis of Wilson's disease in children.
|
J Hepatol
|
2007
|
1.44
|
45
|
Comparison and evaluation of cardiac biomarkers in patients with intermittent claudication: results from the CAVASIC study.
|
Clin Chem
|
2013
|
1.43
|
46
|
Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
|
Exp Gerontol
|
2008
|
1.41
|
47
|
Fifteen-year follow-up of association between telomere length and incident cancer and cancer mortality.
|
JAMA
|
2011
|
1.34
|
48
|
Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies.
|
Circ Cardiovasc Genet
|
2011
|
1.26
|
49
|
Pro-A-type natriuretic peptide and pro-adrenomedullin predict progression of chronic kidney disease: the MMKD Study.
|
Kidney Int
|
2008
|
1.26
|
50
|
Uric acid as a risk factor for progression of non-diabetic chronic kidney disease? The Mild to Moderate Kidney Disease (MMKD) Study.
|
Exp Gerontol
|
2008
|
1.25
|
51
|
Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes.
|
Diabetes
|
2013
|
1.25
|
52
|
INSIG2 polymorphism is neither associated with BMI nor with phenotypes of lipoprotein metabolism.
|
Obesity (Silver Spring)
|
2008
|
1.24
|
53
|
The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes.
|
Diabetes
|
2006
|
1.22
|
54
|
Cloudgene: a graphical execution platform for MapReduce programs on private and public clouds.
|
BMC Bioinformatics
|
2012
|
1.21
|
55
|
Oxidized phospholipids predict the presence and progression of carotid and femoral atherosclerosis and symptomatic cardiovascular disease: five-year prospective results from the Bruneck study.
|
J Am Coll Cardiol
|
2006
|
1.21
|
56
|
Genome-wide association study of lung function decline in adults with and without asthma.
|
J Allergy Clin Immunol
|
2012
|
1.20
|
57
|
Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?
|
PLoS Genet
|
2009
|
1.18
|
58
|
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.
|
Hum Mol Genet
|
2012
|
1.14
|
59
|
Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression.
|
J Proteome Res
|
2005
|
1.13
|
60
|
Epidemiology of dialysis patients and heart failure patients.
|
Semin Nephrol
|
2006
|
1.13
|
61
|
DNA methylation of lipid-related genes affects blood lipid levels.
|
Circ Cardiovasc Genet
|
2015
|
1.12
|
62
|
Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index.
|
Ann Med
|
2009
|
1.10
|
63
|
APOA5 variants and metabolic syndrome in Caucasians.
|
J Lipid Res
|
2007
|
1.09
|
64
|
The German Chronic Kidney Disease (GCKD) study: design and methods.
|
Nephrol Dial Transplant
|
2011
|
1.09
|
65
|
A common variant in the adiponutrin gene influences liver enzyme values.
|
J Med Genet
|
2009
|
1.08
|
66
|
Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins.
|
Hum Mol Genet
|
2009
|
1.08
|
67
|
Association of the MC4R V103I polymorphism with the metabolic syndrome: the KORA Study.
|
Obesity (Silver Spring)
|
2008
|
1.06
|
68
|
Characterization of the vitamin E-binding properties of human plasma afamin.
|
Biochemistry
|
2002
|
1.05
|
69
|
Lost in the space of bioinformatic tools: a constantly updated survival guide for genetic epidemiology. The GenEpi Toolbox.
|
Atherosclerosis
|
2009
|
1.05
|
70
|
Apolipoprotein A-IV predicts progression of chronic kidney disease: the mild to moderate kidney disease study.
|
J Am Soc Nephrol
|
2005
|
1.01
|
71
|
B-type natriuretic peptide concentrations predict the progression of nondiabetic chronic kidney disease: the Mild-to-Moderate Kidney Disease Study.
|
Clin Chem
|
2007
|
1.00
|
72
|
Hemoglobin variability does not predict mortality in European hemodialysis patients.
|
J Am Soc Nephrol
|
2010
|
1.00
|
73
|
A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol.
|
PLoS Genet
|
2011
|
0.97
|
74
|
Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels.
|
PLoS Genet
|
2013
|
0.97
|
75
|
Increased serum lipoprotein(a) concentrations and low molecular weight phenotypes of apolipoprotein(a) are associated with symptomatic peripheral arterial disease.
|
Clin Chem
|
2007
|
0.96
|
76
|
CONAN: copy number variation analysis software for genome-wide association studies.
|
BMC Bioinformatics
|
2010
|
0.95
|
77
|
Genetic associations with lipoprotein subfractions provide information on their biological nature.
|
Hum Mol Genet
|
2011
|
0.95
|
78
|
Different genes interact with particulate matter and tobacco smoke exposure in affecting lung function decline in the general population.
|
PLoS One
|
2012
|
0.95
|
79
|
Association between the UGT1A1 TA-repeat polymorphism and bilirubin concentration in patients with intermittent claudication: results from the CAVASIC study.
|
Clin Chem
|
2008
|
0.94
|
80
|
Investigation and functional characterization of rare genetic variants in the adipose triglyceride lipase in a large healthy working population.
|
PLoS Genet
|
2010
|
0.94
|
81
|
Impact of ENPP1 genotype on arterial calcification in patients with end-stage renal failure.
|
Nephrol Dial Transplant
|
2007
|
0.93
|
82
|
The adiponectin gene is associated with adiponectin levels but not with characteristics of the insulin resistance syndrome in healthy Caucasians.
|
Eur J Hum Genet
|
2006
|
0.93
|
83
|
Sex and age interaction with genetic association of atherogenic uric acid concentrations.
|
Atherosclerosis
|
2009
|
0.93
|
84
|
Evidence for genetic heterogeneity in lymphedema-cholestasis syndrome.
|
J Pediatr
|
2003
|
0.93
|
85
|
Serum bilirubin levels, UGT1A1 polymorphisms and risk for coronary artery disease.
|
Exp Gerontol
|
2008
|
0.92
|
86
|
Evaluation of gene-obesity interaction effects on cholesterol levels: a genetic predisposition score on HDL-cholesterol is modified by obesity.
|
Atherosclerosis
|
2012
|
0.90
|
87
|
Conditional linkage and genome-wide association studies identify UGT1A1 as a major gene for anti-atherogenic serum bilirubin levels--the Framingham Heart Study.
|
Atherosclerosis
|
2009
|
0.90
|
88
|
eCOMPAGT -- efficient combination and management of phenotypes and genotypes for genetic epidemiology.
|
BMC Bioinformatics
|
2009
|
0.90
|
89
|
Do genetic factors protect for early onset lung cancer? A case control study before the age of 50 years.
|
BMC Cancer
|
2008
|
0.89
|
90
|
eCOMPAGT integrates mtDNA: import, validation and export of mitochondrial DNA profiles for population genetics, tumour dynamics and genotype-phenotype association studies.
|
BMC Bioinformatics
|
2010
|
0.89
|
91
|
An epidemiological study of hemodialysis patients based on the European Fresenius Medical Care hemodialysis network: results of the ARO study.
|
Nephron Clin Pract
|
2010
|
0.89
|
92
|
In vivo stable-isotope kinetic study suggests intracellular assembly of lipoprotein(a).
|
Atherosclerosis
|
2012
|
0.89
|
93
|
Intermittent claudication in the Erfurt Male Cohort (ERFORT) Study: its determinants and the impact on mortality. A population-based prospective cohort study with 30 years of follow-up.
|
Atherosclerosis
|
2007
|
0.89
|
94
|
Sex-specific association of time-varying haemoglobin values with mortality in incident dialysis patients.
|
Nephrol Dial Transplant
|
2010
|
0.88
|
95
|
Delayed in vivo catabolism of intermediate-density lipoprotein and low-density lipoprotein in hemodialysis patients as potential cause of premature atherosclerosis.
|
Arterioscler Thromb Vasc Biol
|
2005
|
0.87
|
96
|
Coumarins and survival in incident dialysis patients.
|
Nephrol Dial Transplant
|
2011
|
0.87
|
97
|
Raising the bar on telomere epidemiology.
|
Int J Epidemiol
|
2010
|
0.86
|
98
|
The shared allelic architecture of adiponectin levels and coronary artery disease.
|
Atherosclerosis
|
2013
|
0.86
|
99
|
Increased plasma amylin in type 1 diabetic patients after kidney and pancreas transplantation: A sign of impaired beta-cell function?
|
Diabetes Care
|
2006
|
0.86
|
100
|
Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) deficiencies affect expression of lipolytic activities in mouse adipose tissues.
|
Mol Cell Proteomics
|
2012
|
0.86
|
101
|
Homoarginine and progression of chronic kidney disease: results from the Mild to Moderate Kidney Disease Study.
|
PLoS One
|
2013
|
0.86
|
102
|
microRNAs in nociceptive circuits as predictors of future clinical applications.
|
Front Mol Neurosci
|
2013
|
0.85
|
103
|
Interaction of time-varying albumin and phosphorus on mortality in incident dialysis patients.
|
Clin J Am Soc Nephrol
|
2011
|
0.84
|
104
|
Cigarette smoking and vascular pathology in renal biopsies.
|
Kidney Int
|
2002
|
0.84
|
105
|
Calpain-10 variants and haplotypes are associated with polycystic ovary syndrome in Caucasians.
|
Am J Physiol Endocrinol Metab
|
2006
|
0.84
|
106
|
Association of HbA1c values with mortality and cardiovascular events in diabetic dialysis patients. The INVOR study and review of the literature.
|
PLoS One
|
2011
|
0.84
|
107
|
No association of two functional polymorphisms in human ALOX15 with myocardial infarction.
|
Atherosclerosis
|
2008
|
0.84
|
108
|
Analytical characterization and clinical evaluation of an enzyme-linked immunosorbent assay for measurement of afamin in human plasma.
|
Clin Chim Acta
|
2013
|
0.83
|
109
|
The association of relative telomere length with symptomatic peripheral arterial disease: results from the CAVASIC study.
|
Atherosclerosis
|
2013
|
0.83
|
110
|
Cigarette smoking and chronic allograft nephropathy.
|
Nephrol Dial Transplant
|
2007
|
0.83
|
111
|
Epidemiologic evidence of barometric pressure changes inducing increased reporting of oral pain.
|
Eur J Pain
|
2011
|
0.83
|
112
|
Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts.
|
Atherosclerosis
|
2011
|
0.83
|
113
|
Late referral defined by renal function: association with morbidity and mortality.
|
J Nephrol
|
2004
|
0.83
|
114
|
Common variants in Mendelian kidney disease genes and their association with renal function.
|
J Am Soc Nephrol
|
2013
|
0.82
|
115
|
Lipoprotein(a) as a predictor of cardiovascular disease in a prospectively followed cohort of patients with type 1 diabetes.
|
Diabetes Care
|
2006
|
0.82
|
116
|
The association of mid-regional pro-adrenomedullin and mid-regional pro-atrial natriuretic peptide with mortality in an incident dialysis cohort.
|
PLoS One
|
2011
|
0.82
|
117
|
Apolipoprotein A-IV is an independent predictor of disease activity in patients with inflammatory bowel disease.
|
Inflamm Bowel Dis
|
2007
|
0.82
|
118
|
Plasma distribution of apoA-IV in patients with coronary artery disease and healthy controls.
|
J Lipid Res
|
2003
|
0.82
|
119
|
Macro- and microcirculatory assessment of cold sensitivity after traumatic finger amputation and microsurgical replantation.
|
Arch Orthop Trauma Surg
|
2007
|
0.82
|
120
|
Carotid plaques and their predictive value for cardiovascular disease and all-cause mortality in hemodialysis patients considering renal transplantation: a decade follow-up.
|
Am J Kidney Dis
|
2006
|
0.82
|
121
|
Discovery of serum biomarkers of ovarian cancer using complementary proteomic profiling strategies.
|
Proteomics Clin Appl
|
2014
|
0.82
|
122
|
Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants.
|
Eur J Epidemiol
|
2014
|
0.81
|
123
|
Reproductive factors and its association with peripheral arterial disease in women aged 52-81 years: the KORA F4 study.
|
Atherosclerosis
|
2013
|
0.81
|
124
|
SERPINA1 PiZ and PiS heterozygotes and lung function decline in the SAPALDIA cohort.
|
PLoS One
|
2012
|
0.81
|
125
|
Estimating the single nucleotide polymorphism genotype misclassification from routine double measurements in a large epidemiologic sample.
|
Am J Epidemiol
|
2008
|
0.81
|
126
|
Dietary mono- and polyunsaturated fatty acids similarly increase plasma apolipoprotein A-IV concentrations in healthy men and women.
|
J Nutr
|
2003
|
0.80
|
127
|
Association of the melanocortin-4 receptor V103I polymorphism with dietary intake in severely obese persons.
|
Am J Clin Nutr
|
2008
|
0.80
|
128
|
An optimized procedure for the design and evaluation of Ecotilling assays.
|
BMC Genomics
|
2008
|
0.80
|
129
|
Haplotype misclassification resulting from statistical reconstruction and genotype error, and its impact on association estimates.
|
Ann Hum Genet
|
2010
|
0.80
|
130
|
Role of the kidney in the metabolism of apolipoprotein A-IV: influence of the type of proteinuria.
|
J Lipid Res
|
2006
|
0.80
|
131
|
Association of STR polymorphisms in CMA1 and IL-4 with asthma and atopy: the SAPALDIA cohort.
|
Hum Immunol
|
2010
|
0.80
|
132
|
Serum bilirubin is associated with lung function in a Swiss general population sample.
|
Eur Respir J
|
2013
|
0.80
|
133
|
Modification of the association between PM10 and lung function decline by cadherin 13 polymorphisms in the SAPALDIA cohort: a genome-wide interaction analysis.
|
Environ Health Perspect
|
2014
|
0.80
|
134
|
Family history of diabetes is associated with higher risk for prediabetes: a multicentre analysis from the German Center for Diabetes Research.
|
Diabetologia
|
2013
|
0.79
|
135
|
Association of daytime sleepiness with COMT polymorphism in patients with parkinson disease: a pilot study.
|
Sleep
|
2004
|
0.79
|
136
|
Polymorphisms in the gene regions of the adaptor complex LAMTOR2/LAMTOR3 and their association with breast cancer risk.
|
PLoS One
|
2013
|
0.79
|
137
|
Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium.
|
Atherosclerosis
|
2012
|
0.79
|
138
|
TNFalpha- and NF-kappaB-dependent induction of the chemokine CCL1 in human macrophages exposed to the atherogenic lipoprotein(a).
|
Life Sci
|
2009
|
0.79
|
139
|
Candidate gene sequencing of SLC11A2 and TMPRSS6 in a family with severe anaemia: common SNPs, rare haplotypes, no causative mutation.
|
PLoS One
|
2012
|
0.79
|
140
|
Joubert-like syndrome unlinked to known candidate loci.
|
J Pediatr
|
2004
|
0.79
|
141
|
Sample selection algorithm to improve quality of genotyping from plasma-derived DNA: to separate the wheat from the chaff.
|
Hum Mutat
|
2007
|
0.78
|
142
|
Daytime sleepiness and the COMT val158met polymorphism in patients with Parkinson disease.
|
Sleep
|
2006
|
0.78
|
143
|
Does statin therapy improve cardiovascular outcomes in patients with type 2 diabetes receiving hemodialysis?
|
Nat Clin Pract Nephrol
|
2006
|
0.77
|
144
|
Visualizing interaction effects: a proposal for presentation and interpretation.
|
J Clin Epidemiol
|
2012
|
0.77
|
145
|
Look beyond one's own nose: combination of information from publicly available sources reveals an association of GATA4 polymorphisms with plasma triglycerides.
|
Atherosclerosis
|
2011
|
0.77
|
146
|
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