Florian Kronenberg

Author PubWeight™ 253.74‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010 28.21
2 Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet 2008 12.32
3 New loci associated with kidney function and chronic kidney disease. Nat Genet 2010 5.58
4 Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts. Kidney Int 2011 5.25
5 Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS Genet 2008 5.23
6 A genome-wide perspective of genetic variation in human metabolism. Nat Genet 2009 5.00
7 SLC2A9 influences uric acid concentrations with pronounced sex-specific effects. Nat Genet 2008 4.67
8 Fibroblast growth factor 23 (FGF23) predicts progression of chronic kidney disease: the Mild to Moderate Kidney Disease (MMKD) Study. J Am Soc Nephrol 2007 4.59
9 Telomere length and risk of incident cancer and cancer mortality. JAMA 2010 3.55
10 On the replication of genetic associations: timing can be everything! Am J Hum Genet 2008 3.32
11 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
12 Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet 2011 3.03
13 HaploGrep: a fast and reliable algorithm for automatic classification of mitochondrial DNA haplogroups. Hum Mutat 2010 3.02
14 Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus. Nat Med 2013 2.93
15 Influences on the reduction of relative telomere length over 10 years in the population-based Bruneck Study: introduction of a well-controlled high-throughput assay. Int J Epidemiol 2009 2.87
16 Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting. PLoS One 2010 2.84
17 Serum iPTH, calcium and phosphate, and the risk of mortality in a European haemodialysis population. Nephrol Dial Transplant 2010 2.70
18 CUBN is a gene locus for albuminuria. J Am Soc Nephrol 2011 2.70
19 Discovery of sexual dimorphisms in metabolic and genetic biomarkers. PLoS Genet 2011 2.68
20 Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature 2011 2.59
21 Association of genetic variation on chromosome 9p21 with susceptibility and progression of atherosclerosis: a population-based, prospective study. J Am Coll Cardiol 2008 2.56
22 Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study. PLoS One 2008 2.37
23 Associations of estimated glomerular filtration rate and albuminuria with mortality and renal failure by sex: a meta-analysis. BMJ 2013 2.24
24 Genetic architecture of the APM1 gene and its influence on adiponectin plasma levels and parameters of the metabolic syndrome in 1,727 healthy Caucasians. Diabetes 2006 2.23
25 Association between the UGT1A1*28 allele, bilirubin levels, and coronary heart disease in the Framingham Heart Study. Circulation 2006 2.18
26 Asymmetric dimethylarginine and progression of chronic kidney disease: the mild to moderate kidney disease study. J Am Soc Nephrol 2005 2.00
27 Serum creatinine, cystatin C, and beta-trace protein in diagnostic staging and predicting progression of primary nondiabetic chronic kidney disease. Clin Chem 2010 1.95
28 A genome-wide association study of metabolic traits in human urine. Nat Genet 2011 1.84
29 Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions. Circ Cardiovasc Genet 2008 1.82
30 Association of ankle-brachial index and plaques in the carotid and femoral arteries with cardiovascular events and total mortality in a population-based study with 13 years of follow-up. Eur Heart J 2006 1.82
31 Cellular aging reflected by leukocyte telomere length predicts advanced atherosclerosis and cardiovascular disease risk. Arterioscler Thromb Vasc Biol 2010 1.81
32 Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease. Atherosclerosis 2009 1.80
33 Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck study. Arterioscler Thromb Vasc Biol 2007 1.79
34 Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals. Atherosclerosis 2009 1.78
35 Renal insulin resistance syndrome, adiponectin and cardiovascular events in patients with kidney disease: the mild and moderate kidney disease study. J Am Soc Nephrol 2005 1.74
36 Predictive performance of renal function equations for patients with chronic kidney disease and normal serum creatinine levels. J Am Soc Nephrol 2002 1.70
37 Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet 2012 1.68
38 Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD. PLoS Genet 2011 1.68
39 Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients. Am J Hum Genet 2010 1.67
40 Differences between human plasma and serum metabolite profiles. PLoS One 2011 1.61
41 Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI. Diabetes Care 2008 1.58
42 Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer. Cancer Epidemiol Biomarkers Prev 2008 1.58
43 Lipoprotein metabolism and lipid management in chronic kidney disease. J Am Soc Nephrol 2007 1.53
44 Re-evaluation of the penicillamine challenge test in the diagnosis of Wilson's disease in children. J Hepatol 2007 1.44
45 Comparison and evaluation of cardiac biomarkers in patients with intermittent claudication: results from the CAVASIC study. Clin Chem 2013 1.43
46 Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review. Exp Gerontol 2008 1.41
47 Fifteen-year follow-up of association between telomere length and incident cancer and cancer mortality. JAMA 2011 1.34
48 Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet 2011 1.26
49 Pro-A-type natriuretic peptide and pro-adrenomedullin predict progression of chronic kidney disease: the MMKD Study. Kidney Int 2008 1.26
50 Uric acid as a risk factor for progression of non-diabetic chronic kidney disease? The Mild to Moderate Kidney Disease (MMKD) Study. Exp Gerontol 2008 1.25
51 Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes. Diabetes 2013 1.25
52 INSIG2 polymorphism is neither associated with BMI nor with phenotypes of lipoprotein metabolism. Obesity (Silver Spring) 2008 1.24
53 The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes. Diabetes 2006 1.22
54 Cloudgene: a graphical execution platform for MapReduce programs on private and public clouds. BMC Bioinformatics 2012 1.21
55 Oxidized phospholipids predict the presence and progression of carotid and femoral atherosclerosis and symptomatic cardiovascular disease: five-year prospective results from the Bruneck study. J Am Coll Cardiol 2006 1.21
56 Genome-wide association study of lung function decline in adults with and without asthma. J Allergy Clin Immunol 2012 1.20
57 Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? PLoS Genet 2009 1.18
58 Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet 2012 1.14
59 Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression. J Proteome Res 2005 1.13
60 Epidemiology of dialysis patients and heart failure patients. Semin Nephrol 2006 1.13
61 DNA methylation of lipid-related genes affects blood lipid levels. Circ Cardiovasc Genet 2015 1.12
62 Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index. Ann Med 2009 1.10
63 APOA5 variants and metabolic syndrome in Caucasians. J Lipid Res 2007 1.09
64 The German Chronic Kidney Disease (GCKD) study: design and methods. Nephrol Dial Transplant 2011 1.09
65 A common variant in the adiponutrin gene influences liver enzyme values. J Med Genet 2009 1.08
66 Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins. Hum Mol Genet 2009 1.08
67 Association of the MC4R V103I polymorphism with the metabolic syndrome: the KORA Study. Obesity (Silver Spring) 2008 1.06
68 Characterization of the vitamin E-binding properties of human plasma afamin. Biochemistry 2002 1.05
69 Lost in the space of bioinformatic tools: a constantly updated survival guide for genetic epidemiology. The GenEpi Toolbox. Atherosclerosis 2009 1.05
70 Apolipoprotein A-IV predicts progression of chronic kidney disease: the mild to moderate kidney disease study. J Am Soc Nephrol 2005 1.01
71 B-type natriuretic peptide concentrations predict the progression of nondiabetic chronic kidney disease: the Mild-to-Moderate Kidney Disease Study. Clin Chem 2007 1.00
72 Hemoglobin variability does not predict mortality in European hemodialysis patients. J Am Soc Nephrol 2010 1.00
73 A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. PLoS Genet 2011 0.97
74 Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels. PLoS Genet 2013 0.97
75 Increased serum lipoprotein(a) concentrations and low molecular weight phenotypes of apolipoprotein(a) are associated with symptomatic peripheral arterial disease. Clin Chem 2007 0.96
76 CONAN: copy number variation analysis software for genome-wide association studies. BMC Bioinformatics 2010 0.95
77 Genetic associations with lipoprotein subfractions provide information on their biological nature. Hum Mol Genet 2011 0.95
78 Different genes interact with particulate matter and tobacco smoke exposure in affecting lung function decline in the general population. PLoS One 2012 0.95
79 Association between the UGT1A1 TA-repeat polymorphism and bilirubin concentration in patients with intermittent claudication: results from the CAVASIC study. Clin Chem 2008 0.94
80 Investigation and functional characterization of rare genetic variants in the adipose triglyceride lipase in a large healthy working population. PLoS Genet 2010 0.94
81 Impact of ENPP1 genotype on arterial calcification in patients with end-stage renal failure. Nephrol Dial Transplant 2007 0.93
82 The adiponectin gene is associated with adiponectin levels but not with characteristics of the insulin resistance syndrome in healthy Caucasians. Eur J Hum Genet 2006 0.93
83 Sex and age interaction with genetic association of atherogenic uric acid concentrations. Atherosclerosis 2009 0.93
84 Evidence for genetic heterogeneity in lymphedema-cholestasis syndrome. J Pediatr 2003 0.93
85 Serum bilirubin levels, UGT1A1 polymorphisms and risk for coronary artery disease. Exp Gerontol 2008 0.92
86 Evaluation of gene-obesity interaction effects on cholesterol levels: a genetic predisposition score on HDL-cholesterol is modified by obesity. Atherosclerosis 2012 0.90
87 Conditional linkage and genome-wide association studies identify UGT1A1 as a major gene for anti-atherogenic serum bilirubin levels--the Framingham Heart Study. Atherosclerosis 2009 0.90
88 eCOMPAGT -- efficient combination and management of phenotypes and genotypes for genetic epidemiology. BMC Bioinformatics 2009 0.90
89 Do genetic factors protect for early onset lung cancer? A case control study before the age of 50 years. BMC Cancer 2008 0.89
90 eCOMPAGT integrates mtDNA: import, validation and export of mitochondrial DNA profiles for population genetics, tumour dynamics and genotype-phenotype association studies. BMC Bioinformatics 2010 0.89
91 An epidemiological study of hemodialysis patients based on the European Fresenius Medical Care hemodialysis network: results of the ARO study. Nephron Clin Pract 2010 0.89
92 In vivo stable-isotope kinetic study suggests intracellular assembly of lipoprotein(a). Atherosclerosis 2012 0.89
93 Intermittent claudication in the Erfurt Male Cohort (ERFORT) Study: its determinants and the impact on mortality. A population-based prospective cohort study with 30 years of follow-up. Atherosclerosis 2007 0.89
94 Sex-specific association of time-varying haemoglobin values with mortality in incident dialysis patients. Nephrol Dial Transplant 2010 0.88
95 Delayed in vivo catabolism of intermediate-density lipoprotein and low-density lipoprotein in hemodialysis patients as potential cause of premature atherosclerosis. Arterioscler Thromb Vasc Biol 2005 0.87
96 Coumarins and survival in incident dialysis patients. Nephrol Dial Transplant 2011 0.87
97 Raising the bar on telomere epidemiology. Int J Epidemiol 2010 0.86
98 The shared allelic architecture of adiponectin levels and coronary artery disease. Atherosclerosis 2013 0.86
99 Increased plasma amylin in type 1 diabetic patients after kidney and pancreas transplantation: A sign of impaired beta-cell function? Diabetes Care 2006 0.86
100 Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) deficiencies affect expression of lipolytic activities in mouse adipose tissues. Mol Cell Proteomics 2012 0.86
101 Homoarginine and progression of chronic kidney disease: results from the Mild to Moderate Kidney Disease Study. PLoS One 2013 0.86
102 microRNAs in nociceptive circuits as predictors of future clinical applications. Front Mol Neurosci 2013 0.85
103 Interaction of time-varying albumin and phosphorus on mortality in incident dialysis patients. Clin J Am Soc Nephrol 2011 0.84
104 Cigarette smoking and vascular pathology in renal biopsies. Kidney Int 2002 0.84
105 Calpain-10 variants and haplotypes are associated with polycystic ovary syndrome in Caucasians. Am J Physiol Endocrinol Metab 2006 0.84
106 Association of HbA1c values with mortality and cardiovascular events in diabetic dialysis patients. The INVOR study and review of the literature. PLoS One 2011 0.84
107 No association of two functional polymorphisms in human ALOX15 with myocardial infarction. Atherosclerosis 2008 0.84
108 Analytical characterization and clinical evaluation of an enzyme-linked immunosorbent assay for measurement of afamin in human plasma. Clin Chim Acta 2013 0.83
109 The association of relative telomere length with symptomatic peripheral arterial disease: results from the CAVASIC study. Atherosclerosis 2013 0.83
110 Cigarette smoking and chronic allograft nephropathy. Nephrol Dial Transplant 2007 0.83
111 Epidemiologic evidence of barometric pressure changes inducing increased reporting of oral pain. Eur J Pain 2011 0.83
112 Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts. Atherosclerosis 2011 0.83
113 Late referral defined by renal function: association with morbidity and mortality. J Nephrol 2004 0.83
114 Common variants in Mendelian kidney disease genes and their association with renal function. J Am Soc Nephrol 2013 0.82
115 Lipoprotein(a) as a predictor of cardiovascular disease in a prospectively followed cohort of patients with type 1 diabetes. Diabetes Care 2006 0.82
116 The association of mid-regional pro-adrenomedullin and mid-regional pro-atrial natriuretic peptide with mortality in an incident dialysis cohort. PLoS One 2011 0.82
117 Apolipoprotein A-IV is an independent predictor of disease activity in patients with inflammatory bowel disease. Inflamm Bowel Dis 2007 0.82
118 Plasma distribution of apoA-IV in patients with coronary artery disease and healthy controls. J Lipid Res 2003 0.82
119 Macro- and microcirculatory assessment of cold sensitivity after traumatic finger amputation and microsurgical replantation. Arch Orthop Trauma Surg 2007 0.82
120 Carotid plaques and their predictive value for cardiovascular disease and all-cause mortality in hemodialysis patients considering renal transplantation: a decade follow-up. Am J Kidney Dis 2006 0.82
121 Discovery of serum biomarkers of ovarian cancer using complementary proteomic profiling strategies. Proteomics Clin Appl 2014 0.82
122 Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants. Eur J Epidemiol 2014 0.81
123 Reproductive factors and its association with peripheral arterial disease in women aged 52-81 years: the KORA F4 study. Atherosclerosis 2013 0.81
124 SERPINA1 PiZ and PiS heterozygotes and lung function decline in the SAPALDIA cohort. PLoS One 2012 0.81
125 Estimating the single nucleotide polymorphism genotype misclassification from routine double measurements in a large epidemiologic sample. Am J Epidemiol 2008 0.81
126 Dietary mono- and polyunsaturated fatty acids similarly increase plasma apolipoprotein A-IV concentrations in healthy men and women. J Nutr 2003 0.80
127 Association of the melanocortin-4 receptor V103I polymorphism with dietary intake in severely obese persons. Am J Clin Nutr 2008 0.80
128 An optimized procedure for the design and evaluation of Ecotilling assays. BMC Genomics 2008 0.80
129 Haplotype misclassification resulting from statistical reconstruction and genotype error, and its impact on association estimates. Ann Hum Genet 2010 0.80
130 Role of the kidney in the metabolism of apolipoprotein A-IV: influence of the type of proteinuria. J Lipid Res 2006 0.80
131 Association of STR polymorphisms in CMA1 and IL-4 with asthma and atopy: the SAPALDIA cohort. Hum Immunol 2010 0.80
132 Serum bilirubin is associated with lung function in a Swiss general population sample. Eur Respir J 2013 0.80
133 Modification of the association between PM10 and lung function decline by cadherin 13 polymorphisms in the SAPALDIA cohort: a genome-wide interaction analysis. Environ Health Perspect 2014 0.80
134 Family history of diabetes is associated with higher risk for prediabetes: a multicentre analysis from the German Center for Diabetes Research. Diabetologia 2013 0.79
135 Association of daytime sleepiness with COMT polymorphism in patients with parkinson disease: a pilot study. Sleep 2004 0.79
136 Polymorphisms in the gene regions of the adaptor complex LAMTOR2/LAMTOR3 and their association with breast cancer risk. PLoS One 2013 0.79
137 Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium. Atherosclerosis 2012 0.79
138 TNFalpha- and NF-kappaB-dependent induction of the chemokine CCL1 in human macrophages exposed to the atherogenic lipoprotein(a). Life Sci 2009 0.79
139 Candidate gene sequencing of SLC11A2 and TMPRSS6 in a family with severe anaemia: common SNPs, rare haplotypes, no causative mutation. PLoS One 2012 0.79
140 Joubert-like syndrome unlinked to known candidate loci. J Pediatr 2004 0.79
141 Sample selection algorithm to improve quality of genotyping from plasma-derived DNA: to separate the wheat from the chaff. Hum Mutat 2007 0.78
142 Daytime sleepiness and the COMT val158met polymorphism in patients with Parkinson disease. Sleep 2006 0.78
143 Does statin therapy improve cardiovascular outcomes in patients with type 2 diabetes receiving hemodialysis? Nat Clin Pract Nephrol 2006 0.77
144 Visualizing interaction effects: a proposal for presentation and interpretation. J Clin Epidemiol 2012 0.77
145 Look beyond one's own nose: combination of information from publicly available sources reveals an association of GATA4 polymorphisms with plasma triglycerides. Atherosclerosis 2011 0.77
146 Immunohistochemical localization of apolipoprotein A-IV in human kidney tissue. Kidney Int 2005 0.77
147 Influence of polymorphisms in genes encoding for insulin-like growth factor (IGF)-I, insulin, and IGF-binding protein (IGFBP)-3 on IGF-I, IGF-II, and IGFBP-3 levels in umbilical cord plasma. Horm Res Paediatr 2012 0.77
148 How healthy are your vessels?--Check your urine! Atherosclerosis 2011 0.76
149 Microcirculatory assessment of vascular acrosyndrome in anorexia nervosa and analysis of manifestation factors. J Psychosom Res 2004 0.76
150 Genetic polymorphisms of the main transcription factors for adiponectin gene promoter in regulation of adiponectin levels: association analysis in three European cohorts. PLoS One 2012 0.75
151 Genetic variants in Lp(a) lipoprotein and coronary disease. N Engl J Med 2010 0.75
152 Lipoprotein kinetics in male hemodialysis patients treated with atorvastatin. Clin J Am Soc Nephrol 2013 0.75
153 Mortality in chronic kidney disease and mineral metabolism. JAMA 2011 0.75
154 Correction: Heart Failure in a Cohort of Patients with Chronic Kidney Disease: The GCKD Study. PLoS One 2015 0.75
155 SNPflow: a lightweight application for the processing, storing and automatic quality checking of genotyping assays. PLoS One 2013 0.75
156 Association of bilirubin with cardiovascular outcomes: more hype than substance? Circ Cardiovasc Genet 2010 0.75
157 Mortality and incidence of renal replacement therapy in people with type 1 diabetes mellitus--a three decade long prospective observational study in the Lainz T1DM cohort. J Clin Endocrinol Metab 2014 0.75
158 Proteinuria and hemoglobin levels in patients with primary glomerular disease. Am J Kidney Dis 2005 0.75
159 European Lipoprotein Club: report of the 31st ELC Annual Conference, Tutzing, 8-11 September 2008. Atherosclerosis 2008 0.75
160 Jordan's anomaly in a case of Chanarin-Dorfman syndrome. Br J Haematol 2011 0.75
161 European Lipoprotein Club: Report of the 29th ELC Annual Conference, Tutzing, 4-7 September 2006. Atherosclerosis 2007 0.75
162 Quantifying the contribution of genetic variants for survival phenotypes. Genet Epidemiol 2008 0.75
163 European Lipoprotein Club: Report of the 30th ELC annual conference, Tutzing, 3-6 September 2007. Atherosclerosis 2008 0.75