PubRank

Esther Kellenberger

Author PubWeight™ 18.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A chemogenomic analysis of the transmembrane binding cavity of human G-protein-coupled receptors. Proteins 2006 1.48
2 sc-PDB: a database for identifying variations and multiplicity of 'druggable' binding sites in proteins. Bioinformatics 2011 1.46
3 Allosteric model of maraviroc binding to CC chemokine receptor 5 (CCR5). J Biol Chem 2011 1.25
4 Recovering the true targets of specific ligands by virtual screening of the protein data bank. Proteins 2004 1.20
5 New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection. J Biol Chem 2010 1.16
6 Small neutralizing molecules to inhibit actions of the chemokine CXCL12. J Biol Chem 2008 1.08
7 A simple and fuzzy method to align and compare druggable ligand-binding sites. Proteins 2008 0.99
8 Structural insights into the molecular basis of the ligand promiscuity. J Chem Inf Model 2012 0.95
9 Comparison and druggability prediction of protein-ligand binding sites from pharmacophore-annotated cavity shapes. J Chem Inf Model 2012 0.95
10 Production of calcium-mobilizing metabolites by a novel member of the ADP-ribosyl cyclase family expressed in Schistosoma mansoni. Biochemistry 2005 0.92
11 Dynamics and metal exchange properties of C4C4 RING domains from CNOT4 and the p44 subunit of TFIIH. J Mol Biol 2005 0.87
12 Selective fluorescent nonpeptidic antagonists for vasopressin V₂ GPCR: application to ligand screening and oligomerization assays. J Med Chem 2012 0.85
13 Modeling the allosteric modulation of CCR5 function by Maraviroc. Drug Discov Today Technol 2013 0.83
14 Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates. PLoS One 2012 0.81
15 Structure of the His44 --> Ala single point mutant of the distal finger motif of HIV-1 nucleocapsid protein: a combined NMR, molecular dynamics simulation, and fluorescence study. Biochemistry 2004 0.80
16 Fluorescent derivatives of AC-42 to probe bitopic orthosteric/allosteric binding mechanisms on muscarinic M1 receptors. J Med Chem 2012 0.79
17 Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD(+) catabolizing enzyme. Bioorg Med Chem 2010 0.78
18 Redesign of Schistosoma mansoni NAD+ catabolizing enzyme: active site H103W mutation restores ADP-ribosyl cyclase activity. Biochemistry 2006 0.78
19 Exploration of the orthosteric/allosteric interface in human M1 muscarinic receptors by bitopic fluorescent ligands. Mol Pharmacol 2013 0.76
20 Schistosoma mansoni NAD(+) catabolizing enzyme: identification of key residues in catalysis. Biochim Biophys Acta 2013 0.75