Published in J Biomol Screen on September 27, 2012
Combined inhibition of glycolysis, the pentose cycle, and thioredoxin metabolism selectively increases cytotoxicity and oxidative stress in human breast and prostate cancer. Redox Biol (2014) 0.88
The influence of host genetics on erythrocytes and malaria infection: is there therapeutic potential? Malar J (2015) 0.83
Avoiding Fluorescence Assay Interference-The Case for Diaphorase. Assay Drug Dev Technol (2016) 0.82
Reactive oxygen species initiate a metabolic collapse in hippocampal slices: potential trigger of cortical spreading depression. J Cereb Blood Flow Metab (2014) 0.78
Novel drugs that target the metabolic reprogramming in renal cell cancer. Cancer Metab (2016) 0.76
Emerging Role of the Pentose Phosphate Pathway in Hepatocellular Carcinoma. Front Oncol (2017) 0.75
Compounds from Terminalia mantaly L. (Combretaceae) Stem Bark Exhibit Potent Inhibition against Some Pathogenic Yeasts and Enzymes of Metabolic Significance. Medicines (Basel) (2017) 0.75
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation. Mol Cell (2007) 4.33
Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates. Nat Genet (2009) 3.86
The endophytic fungus Piriformospora indica reprograms barley to salt-stress tolerance, disease resistance, and higher yield. Proc Natl Acad Sci U S A (2005) 2.74
Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect. J Biol Chem (2011) 2.24
Human milk oligosaccharides protect bladder epithelial cells against uropathogenic Escherichia coli invasion and cytotoxicity. J Infect Dis (2013) 2.18
Adaptation of energy metabolism in breast cancer brain metastases. Cancer Res (2007) 2.17
Mitochondrial p32 protein is a critical regulator of tumor metabolism via maintenance of oxidative phosphorylation. Mol Cell Biol (2010) 2.05
Interacting effects of the dopamine transporter gene and psychosocial adversity on attention-deficit/hyperactivity disorder symptoms among 15-year-olds from a high-risk community sample. Arch Gen Psychiatry (2007) 2.02
The human milk oligosaccharide disialyllacto-N-tetraose prevents necrotising enterocolitis in neonatal rats. Gut (2011) 1.92
The thioredoxin system--from science to clinic. Med Res Rev (2004) 1.82
Increased frequency of rolandic spikes in ADHD children. Epilepsia (2003) 1.73
On the potential of thioredoxin reductase inhibitors for cancer therapy. Semin Cancer Biol (2006) 1.63
In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisinins. Antimicrob Agents Chemother (2005) 1.46
Molecular genetics of attention-deficit/hyperactivity disorder: an overview. Eur Child Adolesc Psychiatry (2010) 1.45
Control of nutrient stress-induced metabolic reprogramming by PKCζ in tumorigenesis. Cell (2013) 1.44
Methylene blue as an antimalarial agent. Redox Rep (2003) 1.39
Impact of age at first drink on vulnerability to alcohol-related problems: testing the marker hypothesis in a prospective study of young adults. J Psychiatr Res (2009) 1.37
Impact of psychosocial adversity on alcohol intake in young adults: moderation by the LL genotype of the serotonin transporter polymorphism. Biol Psychiatry (2009) 1.37
Poverty, obesity, and malnutrition: an international perspective recognizing the paradox. J Am Diet Assoc (2007) 1.32
Interactions of methylene blue with human disulfide reductases and their orthologues from Plasmodium falciparum. Antimicrob Agents Chemother (2007) 1.28
Interaction between the 5-HTTLPR serotonin transporter polymorphism and environmental adversity for mood and anxiety psychopathology: evidence from a high-risk community sample of young adults. Int J Neuropsychopharmacol (2009) 1.28
Novelty seeking involved in mediating the association between the dopamine D4 receptor gene exon III polymorphism and heavy drinking in male adolescents: results from a high-risk community sample. Biol Psychiatry (2006) 1.27
Crystal structure of a novel Plasmodium falciparum 1-Cys peroxiredoxin. J Mol Biol (2005) 1.27
Glutathione--functions and metabolism in the malarial parasite Plasmodium falciparum. Biol Chem (2003) 1.23
Compartmentation of redox metabolism in malaria parasites. PLoS Pathog (2010) 1.22
The Plasmodium selenoproteome. Nucleic Acids Res (2006) 1.21
A central strategy for converting natural products into fluorescent probes. Chembiochem (2006) 1.21
A putative glutathione peroxidase of Drosophila encodes a thioredoxin peroxidase that provides resistance against oxidative stress but fails to complement a lack of catalase activity. Biol Chem (2003) 1.20
Human milk oligosaccharides reduce HIV-1-gp120 binding to dendritic cell-specific ICAM3-grabbing non-integrin (DC-SIGN). Br J Nutr (2009) 1.17
Ablation of mouse phosphomannose isomerase (Mpi) causes mannose 6-phosphate accumulation, toxicity, and embryonic lethality. J Biol Chem (2005) 1.16
Crystal structure of the antioxidant enzyme glutathione reductase inactivated by peroxynitrite. J Biol Chem (2001) 1.14
Glutathione S-transferase of the malarial parasite Plasmodium falciparum: characterization of a potential drug target. Biol Chem (2002) 1.14
Mitochondrial and cytoplasmic thioredoxin reductase variants encoded by a single Drosophila gene are both essential for viability. J Biol Chem (2002) 1.12
The Drosophila carbonyl reductase sniffer prevents oxidative stress-induced neurodegeneration. Curr Biol (2004) 1.12
Design and synthesis of pyrazole derivatives as potent and selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP). Bioorg Med Chem Lett (2008) 1.11
Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy. Nat Struct Mol Biol (2009) 1.11
Thioredoxin networks in the malarial parasite Plasmodium falciparum. Antioxid Redox Signal (2006) 1.10
Spectroscopic evidence for participation of the 1',4'-imino tautomer of thiamin diphosphate in catalysis by yeast pyruvate decarboxylase. Bioorg Chem (2002) 1.10
Genetic variation in dopamine pathways differentially associated with smoking progression in adolescence. J Am Acad Child Adolesc Psychiatry (2008) 1.09
Large-scale differential proteome analysis in Plasmodium falciparum under drug treatment. PLoS One (2008) 1.07
Association of the DRD4 exon III polymorphism with smoking in fifteen-year-olds: a mediating role for novelty seeking? J Am Acad Child Adolesc Psychiatry (2005) 1.07
Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits. FASEB J (2012) 1.07
Comparative metabolomics of breast cancer. Pac Symp Biocomput (2007) 1.06
Functional specialization in proline biosynthesis of melanoma. PLoS One (2012) 1.06
Plasmodium falciparum--do killers commit suicide? Trends Parasitol (2004) 1.04
Characterization of the glyoxalases of the malarial parasite Plasmodium falciparum and comparison with their human counterparts. Biol Chem (2005) 1.04
Identification and characterization of heme-interacting proteins in the malaria parasite, Plasmodium falciparum. J Biol Chem (2003) 1.03
Agm1/Pgm3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development. Mol Cell Biol (2007) 1.03
From nature versus nurture, via nature and nurture, to gene x environment interaction in mental disorders. Eur Child Adolesc Psychiatry (2009) 1.02
The malarial parasite Plasmodium falciparum imports the human protein peroxiredoxin 2 for peroxide detoxification. Proc Natl Acad Sci U S A (2009) 1.02
Human milk oligosaccharides reduce Entamoeba histolytica attachment and cytotoxicity in vitro. Br J Nutr (2012) 1.02
High-throughput fluorescence assay for small-molecule inhibitors of autophagins/Atg4. J Biomol Screen (2011) 1.02
HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop. J Mol Cell Biol (2012) 1.02
Thioredoxin and glutathione systems in Plasmodium falciparum. Int J Med Microbiol (2012) 1.02
Protein S-glutathionylation in malaria parasites. Antioxid Redox Signal (2011) 1.01
Crystal structure of the human thioredoxin reductase-thioredoxin complex. Nat Commun (2011) 1.01
Internet chat rooms and suicide. J Am Acad Child Adolesc Psychiatry (2004) 1.00
The thioredoxin specificity of Drosophila GPx: a paradigm for a peroxiredoxin-like mechanism of many glutathione peroxidases. J Mol Biol (2006) 1.00
Undressing of phosphine gold(I) complexes as irreversible inhibitors of human disulfide reductases. Angew Chem Int Ed Engl (2006) 1.00
X-ray structure of glutathione S-transferase from the malarial parasite Plasmodium falciparum. Proc Natl Acad Sci U S A (2003) 1.00
Discovery and characterization of 2-aminobenzimidazole derivatives as selective NOD1 inhibitors. Chem Biol (2011) 0.99
Glutathione S-transferase from malarial parasites: structural and functional aspects. Methods Enzymol (2005) 0.98
Glyoxalase I of the malarial parasite Plasmodium falciparum: evidence for subunit fusion. FEBS Lett (2003) 0.96
Plasmodium falciparum glutathione S-transferase--structural and mechanistic studies on ligand binding and enzyme inhibition. Protein Sci (2005) 0.96
Glucose-dependent de novo lipogenesis in B lymphocytes: a requirement for atp-citrate lyase in lipopolysaccharide-induced differentiation. J Biol Chem (2014) 0.95
Intracellular positioning of isoforms explains an unusually large adenylate kinase gene family in the parasite Trypanosoma brucei. J Biol Chem (2005) 0.94
Neuropsychological basic deficits in preschoolers at risk for ADHD: a meta-analysis. Clin Psychol Rev (2011) 0.94
Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster. J Mol Biol (2004) 0.94
Identification of proteins targeted by the thioredoxin superfamily in Plasmodium falciparum. PLoS Pathog (2009) 0.93
Mechanism-based inactivation of thioredoxin reductase from Plasmodium falciparum by Mannich bases. Implication for cytotoxicity. Biochemistry (2003) 0.93
Visual exploratory behaviour in infancy and novelty seeking in adolescence: two developmentally specific phenotypes of DRD4? J Child Psychol Psychiatry (2006) 0.92
Human placenta thioredoxin reductase: preparation and inhibitor studies. Methods Enzymol (2002) 0.91
The bacterial redox signaller pyocyanin as an antiplasmodial agent: comparisons with its thioanalog methylene blue. Redox Rep (2011) 0.91
A prospective, multicenter, open-label assessment of atomoxetine in non-North American children and adolescents with ADHD. Eur Child Adolesc Psychiatry (2004) 0.90
Redox regulation of Plasmodium falciparum ornithine δ-aminotransferase. J Mol Biol (2010) 0.90
Identification of acid-base catalytic residues of high-Mr thioredoxin reductase from Plasmodium falciparum. J Biol Chem (2006) 0.89
Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum. J Med Chem (2008) 0.89
Potent, selective, and orally available benzoisothiazolone phosphomannose isomerase inhibitors as probes for congenital disorder of glycosylation Ia. J Med Chem (2011) 0.89
Relationship between atomoxetine plasma concentration, treatment response and tolerability in attention-deficit/hyperactivity disorder and comorbid oppositional defiant disorder. Atten Defic Hyperact Disord (2009) 0.89
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy. ACS Chem Neurosci (2012) 0.89
Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents. Biol Chem (2007) 0.89
Glucose-6-phosphate metabolism in Plasmodium falciparum. IUBMB Life (2012) 0.89
Multiple modes of active center communication in thiamin diphosphate-dependent enzymes. Acc Chem Res (2005) 0.89
Mechanistic studies on a novel, highly potent gold-phosphole inhibitor of human glutathione reductase. J Biol Chem (2005) 0.88