Published in Arthritis Rheum on February 01, 2013
Interleukin-6 (IL-6) trans signaling drives a STAT3-dependent pathway that leads to hyperactive transforming growth factor-β (TGF-β) signaling promoting SMAD3 activation and fibrosis via Gremlin protein. J Biol Chem (2014) 1.12
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Emerging role of epigenetics in systemic sclerosis pathogenesis. Genes Immun (2014) 0.81
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Serum amyloid A induces interleukin-6 in dermal fibroblasts via Toll-like receptor 2, interleukin-1 receptor-associated kinase 4 and nuclear factor-κB. Immunology (2014) 0.80
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IL-13 mediates collagen deposition via STAT6 and microRNA-135b: a role for epigenetics. Sci Rep (2016) 0.76
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Mechanistic insight into the norepinephrine-induced fibrosis in systemic sclerosis. Sci Rep (2016) 0.75
2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative. Arthritis Rheum (2013) 5.99
Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells. Nat Rev Immunol (2008) 4.17
Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial. Lancet (2013) 3.83
Human tissues contain CD141hi cross-presenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells. Immunity (2012) 3.58
IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med (2011) 3.29
Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency. Blood (2011) 3.16
Comparison of gene expression profiles between human and mouse monocyte subsets. Blood (2009) 3.15
2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative. Ann Rheum Dis (2013) 3.11
The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency. J Exp Med (2011) 2.96
IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses. Immunity (2013) 2.69
Effective treatment of collagen-induced arthritis by adoptive transfer of CD25+ regulatory T cells. Arthritis Rheum (2005) 2.32
BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups. J Exp Med (2014) 2.23
Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation. J Exp Med (2009) 1.96
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Involvement of functional autoantibodies against vascular receptors in systemic sclerosis. Ann Rheum Dis (2010) 1.83
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Dysregulated lymphocyte proliferation and differentiation in patients with rheumatoid arthritis. Blood (2002) 1.57
Biallelic mutations in IRF8 impair human NK cell maturation and function. J Clin Invest (2016) 1.39
Immunohistochemical analysis as a means to predict responsiveness to rituximab treatment. Arthritis Rheum (2007) 1.38
The evolution of cellular deficiency in GATA2 mutation. Blood (2013) 1.36
Human dendritic cell deficiency: the missing ID? Nat Rev Immunol (2011) 1.32
A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations. Hum Mol Genet (2011) 1.24
The clinical utility of bone marker measurements in osteoporosis. J Transl Med (2013) 1.21
Ontogeny and functional specialization of dendritic cells in human and mouse. Adv Immunol (2013) 1.15
Interleukin-6 (IL-6) trans signaling drives a STAT3-dependent pathway that leads to hyperactive transforming growth factor-β (TGF-β) signaling promoting SMAD3 activation and fibrosis via Gremlin protein. J Biol Chem (2014) 1.12
The Met-196 -> Arg variation of human tumor necrosis factor receptor 2 (TNFR2) affects TNF-alpha-induced apoptosis by impaired NF-kappaB signaling and target gene expression. J Biol Chem (2004) 1.07
A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort. Ann Rheum Dis (2010) 1.05
T cells in systemic sclerosis: a reappraisal. Rheumatology (Oxford) (2012) 1.05
Interleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia. Arthritis Res Ther (2004) 1.04
Haematopoietic and immune defects associated with GATA2 mutation. Br J Haematol (2015) 1.04
Rap1 signaling is required for suppression of Ras-generated reactive oxygen species and protection against oxidative stress in T lymphocytes. J Immunol (2004) 1.00
Residual inflammation after rituximab treatment is associated with sustained synovial plasma cell infiltration and enhanced B cell repopulation. Ann Rheum Dis (2008) 0.99
Dendritic cell, monocyte, B and NK lymphoid deficiency defines the lost lineages of a new GATA-2 dependent myelodysplastic syndrome. Haematologica (2011) 0.98
Nanoscale arrangement of apoptotic ligands reveals a demand for a minimal lateral distance for efficient death receptor activation. Nano Lett (2009) 0.98
The Milwaukee shoulder/knee syndrome. J Clin Rheumatol (2008) 0.97
Autologous HSCT for systemic sclerosis. Lancet (2013) 0.97
Single chain TNF derivatives with individually mutated receptor binding sites reveal differential stoichiometry of ligand receptor complex formation for TNFR1 and TNFR2. Cell Signal (2010) 0.97
Interleukin-6, its role in fibrosing conditions. Cytokine Growth Factor Rev (2012) 0.96
Cell therapy for autoimmune diseases. Arthritis Res Ther (2007) 0.95
The c-Rel subunit of NF-κB regulates epidermal homeostasis and promotes skin fibrosis in mice. Am J Pathol (2013) 0.94
Stem cell transplantation for rheumatic autoimmune diseases. Arthritis Res Ther (2008) 0.93
Dual function of cysteine rich domain (CRD) 1 of TNF receptor type 1: conformational stabilization of CRD2 and control of receptor responsiveness. Cell Signal (2010) 0.92
Pulmonary fibrosis in a patient with rheumatoid arthritis treated with adalimumab. Arthritis Rheum (2006) 0.91
Tumor necrosis factor (TNF)-functionalized nanostructured particles for the stimulation of membrane TNF-specific cell responses. Bioconjug Chem (2005) 0.91
Toll-like receptor-mediated, enhanced production of profibrotic TIMP-1 in monocytes from patients with systemic sclerosis: role of serum factors. Ann Rheum Dis (2012) 0.91
The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis. PLoS One (2013) 0.91
A multicenter study confirms CD226 gene association with systemic sclerosis-related pulmonary fibrosis. Arthritis Res Ther (2012) 0.90
Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factors in a large independent replication study. Ann Rheum Dis (2012) 0.89
Influence of the IL6 gene in susceptibility to systemic sclerosis. J Rheumatol (2012) 0.88
Mast cells are a source of transforming growth factor β in systemic sclerosis. Arthritis Rheum (2011) 0.88
Confirmation of association of the macrophage migration inhibitory factor gene with systemic sclerosis in a large European population. Rheumatology (Oxford) (2011) 0.88
The tumor necrosis factor receptor stalk regions define responsiveness to soluble versus membrane-bound ligand. Mol Cell Biol (2012) 0.88
Autologous hematopoietic stem cell transplantation for autoimmune disease--is it now ready for prime time? Biol Blood Marrow Transplant (2012) 0.87
Role of innate immune system in systemic sclerosis. Semin Immunopathol (2015) 0.87
Differential responsiveness to immunoablative therapy in refractory rheumatoid arthritis is associated with level and avidity of anti-cyclic citrullinated protein autoantibodies: a case study. Arthritis Res Ther (2007) 0.86
Inhibition of RelA-Ser536 phosphorylation by a competing peptide reduces mouse liver fibrosis without blocking the innate immune response. Hepatology (2013) 0.86
Rituximab fixed retreatment versus on-demand retreatment in refractory rheumatoid arthritis: comparison of two B cell depleting treatment strategies. Ann Rheum Dis (2009) 0.86
Induction of long-term B-cell depletion in refractory rheumatoid arthritis patients preferentially affects autoreactive more than protective humoral immunity. Arthritis Res Ther (2012) 0.86
Differentiation potential of CD14+ monocytes into myofibroblasts in patients with systemic sclerosis. PLoS One (2012) 0.86
Connecting the dots: monocyte/DC and NK subsets in human peripheral blood. Blood (2010) 0.85
Association of a non-synonymous functional variant of the ITGAM gene with systemic sclerosis. Ann Rheum Dis (2011) 0.85
Langerhans cell homeostasis and turnover after nonmyeloablative and myeloablative allogeneic hematopoietic cell transplantation. Transplantation (2014) 0.85
Ligand-induced internalization of TNF receptor 2 mediated by a di-leucin motif is dispensable for activation of the NFκB pathway. Cell Signal (2010) 0.84
Role of toll-like receptors in systemic sclerosis. Expert Rev Mol Med (2013) 0.84
Stem cells in the treatment of inflammatory arthritis. Best Pract Res Clin Rheumatol (2010) 0.84
The role of B cells in systemic sclerosis. Biologics (2008) 0.84
Prognostic significance of interleukin-7 receptor-α gene polymorphisms in allogeneic stem-cell transplantation: a confirmatory study. Transplantation (2011) 0.83
Update on stem cell transplantation for systemic sclerosis: recent trial results. Curr Rheumatol Rep (2013) 0.83
Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility. Ann Rheum Dis (2012) 0.83
Regulatory T cells inhibit CD8(+) T-cell tissue invasion in human skin graft-versus-host reactions. Transplantation (2012) 0.83
Dendritic cell homeostasis and trafficking in transplantation. Trends Immunol (2007) 0.83
Functional characterization of the human dendritic cell immunodeficiency associated with the IRF8(K108E) mutation. Blood (2014) 0.82
Cross-linked actin networks (CLANs) are present in lamina cribrosa cells. Br J Ophthalmol (2010) 0.82
Identification of human tissue cross-presenting dendritic cells: A new target for cancer vaccines. Oncoimmunology (2013) 0.81
Needs and preferences regarding health care delivery as perceived by patients with systemic sclerosis. Clin Rheumatol (2011) 0.81
New insight on the Xq28 association with systemic sclerosis. Ann Rheum Dis (2013) 0.81
Targeting host B-cell immune responses by persistent donor NK-cell alloreactivity following nonmyeloablative allogeneic stem cell transplantation. Blood (2007) 0.81
A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility. Arthritis Res Ther (2014) 0.80
The critical role of TAK1 in accentuated epithelial to mesenchymal transition in obliterative bronchiolitis after lung transplantation. Am J Pathol (2012) 0.80
Serum amyloid A induces interleukin-6 in dermal fibroblasts via Toll-like receptor 2, interleukin-1 receptor-associated kinase 4 and nuclear factor-κB. Immunology (2014) 0.80
A shift towards pro-inflammatory CD16+ monocyte subsets with preserved cytokine production potential after kidney transplantation. PLoS One (2013) 0.80
Sensitizing primary acute lymphoblastic leukemia to natural killer cell recognition by induction of NKG2D ligands. Leuk Lymphoma (2012) 0.80
Late-onset systemic sclerosis--a systematic survey of the EULAR scleroderma trials and research group database. Rheumatology (Oxford) (2010) 0.80