| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
Nature
|
2011
|
13.25
|
|
2
|
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
|
Nature
|
2011
|
13.23
|
|
3
|
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
|
Nat Genet
|
2010
|
8.48
|
|
4
|
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
|
Nat Genet
|
2013
|
7.44
|
|
5
|
CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis.
|
JAMA
|
2011
|
5.93
|
|
6
|
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility.
|
Nat Genet
|
2011
|
5.56
|
|
7
|
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.
|
Nat Genet
|
2009
|
4.61
|
|
8
|
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes.
|
Nat Genet
|
2010
|
4.42
|
|
9
|
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke.
|
Nat Genet
|
2012
|
3.40
|
|
10
|
Estimation of bias in nongenetic observational studies using "mendelian triangulation".
|
Ann Epidemiol
|
2006
|
2.57
|
|
11
|
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
|
Am J Hum Genet
|
2012
|
2.53
|
|
12
|
Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials.
|
Lancet
|
2011
|
2.35
|
|
13
|
Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.
|
J Am Coll Cardiol
|
2013
|
2.18
|
|
14
|
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.
|
Am J Hum Genet
|
2010
|
2.15
|
|
15
|
Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts.
|
Int J Epidemiol
|
2008
|
2.14
|
|
16
|
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
Am J Hum Genet
|
2012
|
1.96
|
|
17
|
Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream.
|
PLoS Med
|
2008
|
1.95
|
|
18
|
Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure.
|
J Natl Cancer Inst
|
2012
|
1.83
|
|
19
|
Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.
|
Eur Heart J
|
2011
|
1.73
|
|
20
|
Statins for all by the age of 50 years?
|
Lancet
|
2012
|
1.69
|
|
21
|
Tackling non-communicable diseases in low- and middle-income countries: is the evidence from high-income countries all we need?
|
PLoS Med
|
2013
|
1.67
|
|
22
|
Congestive heart failure in Latin America: the next epidemic.
|
Am Heart J
|
2004
|
1.58
|
|
23
|
Major cardiovascular risk factors in Latin America: a comparison with the United States. The Latin American Consortium of Studies in Obesity (LASO).
|
PLoS One
|
2013
|
1.56
|
|
24
|
Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.
|
Nat Genet
|
2012
|
1.52
|
|
25
|
Noncommunicable diseases and injuries in Latin America and the Caribbean: time for action.
|
PLoS Med
|
2006
|
1.49
|
|
26
|
Bayesian meta-analysis of genetic association studies with different sets of markers.
|
Am J Hum Genet
|
2008
|
1.44
|
|
27
|
Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.
|
PLoS One
|
2009
|
1.43
|
|
28
|
Could NICE guidance on the choice of blood pressure lowering drugs be simplified?
|
BMJ
|
2012
|
1.41
|
|
29
|
Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals.
|
PLoS Med
|
2007
|
1.38
|
|
30
|
Unintended effects of statins from observational studies in the general population: systematic review and meta-analysis.
|
BMC Med
|
2014
|
1.31
|
|
31
|
Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies.
|
Eur Heart J
|
2012
|
1.30
|
|
32
|
Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals.
|
Atherosclerosis
|
2010
|
1.27
|
|
33
|
Biomarkers of inflammation predict both vascular and non-vascular mortality in older men.
|
Eur Heart J
|
2008
|
1.22
|
|
34
|
Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms.
|
Circulation
|
2009
|
1.20
|
|
35
|
Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.
|
Hum Mol Genet
|
2009
|
1.17
|
|
36
|
Ancestry as a determinant of mean population C-reactive protein values: implications for cardiovascular risk prediction.
|
Circ Cardiovasc Genet
|
2010
|
1.16
|
|
37
|
Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis.
|
Nat Genet
|
2013
|
1.15
|
|
38
|
Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype.
|
Int J Epidemiol
|
2012
|
1.12
|
|
39
|
Interleukin-6 receptor pathways in abdominal aortic aneurysm.
|
Eur Heart J
|
2012
|
1.12
|
|
40
|
Does high C-reactive protein concentration increase atherosclerosis? The Whitehall II Study.
|
PLoS One
|
2008
|
1.09
|
|
41
|
C-reactive protein (+1444C>T) polymorphism influences CRP response following a moderate inflammatory stimulus.
|
Atherosclerosis
|
2004
|
1.07
|
|
42
|
UCHL-1 is not a Parkinson's disease susceptibility gene.
|
Ann Neurol
|
2006
|
1.06
|
|
43
|
Endothelial NO synthase genotype and risk of preeclampsia: a multicenter case-control study.
|
Hypertension
|
2004
|
1.04
|
|
44
|
Area-level deprivation and overall and cause-specific mortality: 12 years' observation on British women and systematic review of prospective studies.
|
PLoS One
|
2013
|
1.04
|
|
45
|
Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals.
|
Int J Epidemiol
|
2013
|
1.03
|
|
46
|
Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.
|
PLoS One
|
2013
|
1.02
|
|
47
|
Multilocus Bayesian meta-analysis of gene-disease associations.
|
Am J Hum Genet
|
2009
|
1.00
|
|
48
|
(6R)-5,6,7,8-tetrahydro-L-biopterin and its stereoisomer prevent ischemia reperfusion injury in human forearm.
|
Arterioscler Thromb Vasc Biol
|
2007
|
0.99
|
|
49
|
Social capital, mortality, cardiovascular events and cancer: a systematic review of prospective studies.
|
Int J Epidemiol
|
2014
|
0.98
|
|
50
|
C-reactive protein and coronary heart disease: predictive test or therapeutic target?
|
Clin Chem
|
2008
|
0.97
|
|
51
|
Modelling the association of disability according to the WHO International Classification of Functioning, Disability and Health (ICF) with mortality in the British Women's Heart and Health Study.
|
J Epidemiol Community Health
|
2011
|
0.96
|
|
52
|
Genetic association studies in pre-eclampsia: systematic meta-analyses and field synopsis.
|
Int J Epidemiol
|
2012
|
0.95
|
|
53
|
Predictors of patterns of change in health-related quality of life in older women over 7 years: evidence from a prospective cohort study.
|
Age Ageing
|
2013
|
0.94
|
|
54
|
Missing data methods in Mendelian randomization studies with multiple instruments.
|
Am J Epidemiol
|
2011
|
0.93
|
|
55
|
Using waist circumference as a screening tool to identify Colombian subjects at cardiovascular risk.
|
Eur J Cardiovasc Prev Rehabil
|
2003
|
0.91
|
|
56
|
Linking observational and genetic approaches to determine the role of C-reactive protein in heart disease risk.
|
Eur Heart J
|
2006
|
0.91
|
|
57
|
Frequency of eNOS polymorphisms in the Colombian general population.
|
BMC Genet
|
2010
|
0.91
|
|
58
|
Angiotensin-converting enzyme I/D polymorphism and preeclampsia risk: evidence of small-study bias.
|
PLoS Med
|
2006
|
0.91
|
|
59
|
A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation.
|
Biol Psychiatry
|
2013
|
0.87
|
|
60
|
Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers.
|
Circ Cardiovasc Genet
|
2013
|
0.86
|
|
61
|
Regional pathologies and globalization of clinical trials: has the time for regional trials arrived?
|
Circulation
|
2003
|
0.85
|
|
62
|
A 'polypill' aimed at preventing cardiovascular disease could prove highly cost-effective for use in Latin America.
|
Health Aff (Millwood)
|
2013
|
0.84
|
|
63
|
Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and development of pre-eclampsia: a case-control study and a meta-analysis.
|
BMC Pregnancy Childbirth
|
2006
|
0.83
|
|
64
|
Plasma concentrations of asymmetric dimethylarginine (ADMA) in Colombian women with pre-eclampsia.
|
JAMA
|
2004
|
0.82
|
|
65
|
Effect of changes in moderate or vigorous physical activity on changes in health-related quality of life of elderly British women over seven years.
|
Qual Life Res
|
2012
|
0.81
|
|
66
|
The role of infection in cardiovascular disease: more support but many questions remain.
|
Eur Heart J
|
2007
|
0.81
|
|
67
|
Inflammation, coagulation and risk of locomotor disability in elderly women: findings from the British Women's Heart and Health Study.
|
Eur J Epidemiol
|
2012
|
0.79
|
|
68
|
CHARITY: Chagas cardiomyopathy bisoprolol intervention study: a randomized double-blind placebo force-titration controlled study with Bisoprolol in patients with chronic heart failure secondary to Chagas cardiomyopathy [NCT00323973].
|
Trials
|
2006
|
0.78
|
|
69
|
Alcohol consumption and cognitive performance: a Mendelian randomization study.
|
Addiction
|
2014
|
0.78
|
|
70
|
Is it important to measure or reduce C-reactive protein in people at risk of cardiovascular disease?
|
Eur Heart J
|
2012
|
0.77
|
|
71
|
Oxygen therapy in acute myocardial infarction – good or bad?
|
Cochrane Database Syst Rev
|
2013
|
0.76
|
|
72
|
Reply: limits of Mendelian randomization analyses in selection of secretory phospholipase A2-IIA as a valid therapeutic target for prevention of cardiovascular disease.
|
J Am Coll Cardiol
|
2013
|
0.76
|
|
73
|
Putting genomics into practice.
|
BMJ
|
2011
|
0.75
|
|
74
|
Ximelagatran or warfarin in atrial fibrillation?
|
Lancet
|
2004
|
0.75
|