| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
Nature
|
2011
|
13.25
|
|
2
|
C-reactive protein and its role in metabolic syndrome: mendelian randomisation study.
|
Lancet
|
2005
|
5.51
|
|
3
|
Hardy-Weinberg equilibrium testing of biological ascertainment for Mendelian randomization studies.
|
Am J Epidemiol
|
2009
|
4.70
|
|
4
|
Predicting the functional, molecular, and phenotypic consequences of amino acid substitutions using hidden Markov models.
|
Hum Mutat
|
2012
|
3.60
|
|
5
|
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
|
Am J Hum Genet
|
2012
|
2.53
|
|
6
|
Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.
|
J Am Coll Cardiol
|
2013
|
2.18
|
|
7
|
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.
|
Am J Hum Genet
|
2010
|
2.15
|
|
8
|
Predicting the functional consequences of cancer-associated amino acid substitutions.
|
Bioinformatics
|
2013
|
2.12
|
|
9
|
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
|
Am J Hum Genet
|
2009
|
2.04
|
|
10
|
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
Am J Hum Genet
|
2012
|
1.96
|
|
11
|
Blood pressure loci identified with a gene-centric array.
|
Am J Hum Genet
|
2011
|
1.44
|
|
12
|
Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies.
|
Eur Heart J
|
2012
|
1.30
|
|
13
|
The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants.
|
PLoS One
|
2008
|
1.28
|
|
14
|
Loci influencing blood pressure identified using a cardiovascular gene-centric array.
|
Hum Mol Genet
|
2013
|
1.27
|
|
15
|
The association of the PON1 Q192R polymorphism with coronary heart disease: findings from the British Women's Heart and Health cohort study and a meta-analysis.
|
BMC Genet
|
2004
|
1.12
|
|
16
|
TAS2R38 (phenylthiocarbamide) haplotypes, coronary heart disease traits, and eating behavior in the British Women's Heart and Health Study.
|
Am J Clin Nutr
|
2005
|
1.06
|
|
17
|
Molecular genetics of human growth hormone, insulin-like growth factors and their pathways in common disease.
|
Hum Genet
|
2007
|
1.06
|
|
18
|
Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals.
|
Int J Epidemiol
|
2013
|
1.03
|
|
19
|
Variants in the human insulin gene that affect pre-mRNA splicing: is -23HphI a functional single nucleotide polymorphism at IDDM2?
|
Diabetes
|
2006
|
1.01
|
|
20
|
Haplotypic analyses of the IGF2-INS-TH gene cluster in relation to cardiovascular risk traits.
|
Hum Mol Genet
|
2004
|
1.00
|
|
21
|
The relationship between plasma angiopoietin-like protein 4 levels, angiopoietin-like protein 4 genotype, and coronary heart disease risk.
|
Arterioscler Thromb Vasc Biol
|
2010
|
1.00
|
|
22
|
Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy.
|
Circ Cardiovasc Genet
|
2011
|
0.99
|
|
23
|
Molecular and population analysis of natural selection on the human haptoglobin duplication.
|
Ann Hum Genet
|
2012
|
0.98
|
|
24
|
Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip.
|
Ann Hum Genet
|
2011
|
0.96
|
|
25
|
Late life metabolic syndrome, early growth, and common polymorphism in the growth hormone and placental lactogen gene cluster.
|
J Clin Endocrinol Metab
|
2004
|
0.95
|
|
26
|
A pathway-based data integration framework for prediction of disease progression.
|
Bioinformatics
|
2013
|
0.95
|
|
27
|
Replication of IGF2-INS-TH*5 haplotype effect on obesity in older men and study of related phenotypes.
|
Eur J Hum Genet
|
2006
|
0.94
|
|
28
|
From a single whole exome read to notions of clinical screening: primary ciliary dyskinesia and RSPH9 p.Lys268del in the Arabian Peninsula.
|
Ann Hum Genet
|
2012
|
0.94
|
|
29
|
The association of the PON1 Q192R polymorphism with complications and outcomes of pregnancy: findings from the British Women's Heart and Health cohort study.
|
Paediatr Perinat Epidemiol
|
2006
|
0.94
|
|
30
|
Combined analysis of CHRNA5, CHRNA3 and CYP2A6 in relation to adolescent smoking behaviour.
|
J Psychopharmacol
|
2011
|
0.87
|
|
31
|
Amplification ratio control system for copy number variation genotyping.
|
Nucleic Acids Res
|
2011
|
0.85
|
|
32
|
Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations.
|
Hum Mol Genet
|
2013
|
0.84
|
|
33
|
Quantitated transcript haplotypes (QTH) of AGTR1, reduced abundance of mRNA haplotypes containing 1166C (rs5186:A>C), and relevance to metabolic syndrome traits.
|
Hum Mutat
|
2007
|
0.82
|
|
34
|
The association of the paraoxonase (PON1) Q192R polymorphism with depression in older women: findings from the British Women's Heart and Health Study.
|
J Epidemiol Community Health
|
2007
|
0.82
|
|
35
|
A study of TH01 and IGF2-INS-TH haplotypes in relation to smoking initiation in three independent surveys.
|
Pharmacogenet Genomics
|
2006
|
0.82
|
|
36
|
Complexity of a complex trait locus: HP, HPR, haemoglobin and cholesterol.
|
Gene
|
2012
|
0.82
|
|
37
|
Homogeneous assay of rs4343, an ACE I/D proxy, and an analysis in the British Women's Heart and Health Study (BWHHS).
|
Dis Markers
|
2008
|
0.81
|
|
38
|
A multi-cohort study of polymorphisms in the GH/IGF axis and physical capability: the HALCyon programme.
|
PLoS One
|
2012
|
0.80
|
|
39
|
Null mutation in human ciliary neurotrophic factor gene confers higher body mass index in males.
|
Eur J Hum Genet
|
2002
|
0.79
|
|
40
|
Interaction between birthweight and polymorphism in the calcium-sensing receptor gene in determination of adult bone mass: the Hertfordshire cohort study.
|
J Rheumatol
|
2007
|
0.79
|
|
41
|
Nonsense mutation in coiled-coil domain containing 151 gene (CCDC151) causes primary ciliary dyskinesia.
|
Hum Mutat
|
2014
|
0.79
|
|
42
|
Questioning INS VNTR role in obesity and diabetes: subclasses tag IGF2-INS-TH haplotypes; and -23HphI as a STEP (splicing and translational efficiency polymorphism).
|
Physiol Genomics
|
2006
|
0.78
|
|
43
|
A study of relationships between single nucleotide polymorphisms from the growth hormone-insulin-like growth factor axis and bone mass: the Hertfordshire cohort study.
|
J Rheumatol
|
2009
|
0.78
|
|
44
|
Haplotype of growth hormone and angiotensin I-converting enzyme genes, serum angiotensin I-converting enzyme and ventricular growth: pathway inference in pharmacogenetics.
|
Pharmacogenet Genomics
|
2007
|
0.78
|
|
45
|
Sequential sentinel SNP Regional Association Plots (SSS-RAP): an approach for testing independence of SNP association signals using meta-analysis data.
|
Ann Hum Genet
|
2013
|
0.77
|
|
46
|
Genome-wide data-mining of candidate human splice translational efficiency polymorphisms (STEPs) and an online database.
|
PLoS One
|
2010
|
0.77
|
|
47
|
Comment on: Marchand and Polychronakos (2007) Evaluation of polymorphic splicing in the mechanism of the association of the insulin gene with diabetes: Diabetes 56:709-713.
|
Diabetes
|
2007
|
0.76
|
|
48
|
MeltMADGE for mutation scanning of specific genes in population studies.
|
Nat Protoc
|
2010
|
0.75
|
|
49
|
Population mutation scanning of human GHR by meltMADGE and identification of a paucimorphic variant.
|
Genet Test Mol Biomarkers
|
2011
|
0.75
|
|
50
|
Analysis of potential genomic confounding in genetic association studies and an online genomic confounding browser (GCB).
|
Ann Hum Genet
|
2011
|
0.75
|