| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease.
|
JAMA
|
2005
|
6.14
|
|
2
|
Diastolic dysfunction is an independent risk factor for death in patients with sickle cell disease.
|
J Am Coll Cardiol
|
2007
|
2.76
|
|
3
|
A network model to predict the risk of death in sickle cell disease.
|
Blood
|
2007
|
2.39
|
|
4
|
Platelet activation in patients with sickle disease, hemolysis-associated pulmonary hypertension, and nitric oxide scavenging by cell-free hemoglobin.
|
Blood
|
2007
|
2.31
|
|
5
|
An official American Thoracic Society clinical practice guideline: diagnosis, risk stratification, and management of pulmonary hypertension of sickle cell disease.
|
Am J Respir Crit Care Med
|
2014
|
2.23
|
|
6
|
Elevated tricuspid regurgitant jet velocity in children and adolescents with sickle cell disease: association with hemolysis and hemoglobin oxygen desaturation.
|
Haematologica
|
2009
|
2.20
|
|
7
|
N-terminal pro-brain natriuretic peptide levels and risk of death in sickle cell disease.
|
JAMA
|
2006
|
2.04
|
|
8
|
Echocardiographic markers of elevated pulmonary pressure and left ventricular diastolic dysfunction are associated with exercise intolerance in adults and adolescents with homozygous sickle cell anemia in the United States and United Kingdom.
|
Circulation
|
2011
|
2.01
|
|
9
|
Chronic hyper-hemolysis in sickle cell anemia: association of vascular complications and mortality with less frequent vasoocclusive pain.
|
PLoS One
|
2008
|
1.75
|
|
10
|
The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe.
|
Haematologica
|
2012
|
1.72
|
|
11
|
Mortality in adults with sickle cell disease and pulmonary hypertension.
|
JAMA
|
2012
|
1.72
|
|
12
|
Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity.
|
Blood
|
2011
|
1.64
|
|
13
|
A novel molecular signature for elevated tricuspid regurgitation velocity in sickle cell disease.
|
Am J Respir Crit Care Med
|
2012
|
1.63
|
|
14
|
Sildenafil therapy in patients with sickle cell disease and pulmonary hypertension.
|
Br J Haematol
|
2005
|
1.47
|
|
15
|
Nitric oxide for inhalation in the acute treatment of sickle cell pain crisis: a randomized controlled trial.
|
JAMA
|
2011
|
1.38
|
|
16
|
Cardiopulmonary complications of sickle cell disease: role of nitric oxide and hemolytic anemia.
|
Hematology Am Soc Hematol Educ Program
|
2005
|
1.36
|
|
17
|
Hemolysis-associated pulmonary hypertension in thalassemia.
|
Ann N Y Acad Sci
|
2005
|
1.35
|
|
18
|
Severity of pulmonary hypertension during vaso-occlusive pain crisis and exercise in patients with sickle cell disease.
|
Br J Haematol
|
2006
|
1.34
|
|
19
|
Prevalence and risk factors for pulmonary artery systolic hypertension among sickle cell disease patients in Nigeria.
|
Am J Hematol
|
2008
|
1.34
|
|
20
|
Increased pulmonary pressures and myocardial wall stress in children with severe malaria.
|
J Infect Dis
|
2010
|
1.33
|
|
21
|
A systematic comparison and evaluation of high density exon arrays and RNA-seq technology used to unravel the peripheral blood transcriptome of sickle cell disease.
|
BMC Med Genomics
|
2012
|
1.29
|
|
22
|
Pulmonary hypertension and NO in sickle cell.
|
Blood
|
2010
|
1.28
|
|
23
|
High levels of placenta growth factor in sickle cell disease promote pulmonary hypertension.
|
Blood
|
2010
|
1.22
|
|
24
|
Prospective echocardiography assessment of pulmonary hypertension and its potential etiologies in children with sickle cell disease.
|
Am J Cardiol
|
2009
|
1.22
|
|
25
|
Improvement in hemolysis and pulmonary arterial systolic pressure in adult patients with sickle cell disease during treatment with hydroxyurea.
|
Am J Hematol
|
2009
|
1.20
|
|
26
|
Proteomic identification of altered apolipoprotein patterns in pulmonary hypertension and vasculopathy of sickle cell disease.
|
Blood
|
2008
|
1.18
|
|
27
|
Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell disease.
|
Blood
|
2009
|
1.16
|
|
28
|
Elevated tricuspid regurgitation velocity and decline in exercise capacity over 22 months of follow up in children and adolescents with sickle cell anemia.
|
Haematologica
|
2010
|
1.16
|
|
29
|
Sickle cell disease and pulmonary hypertension in Africa: a global perspective and review of epidemiology, pathophysiology, and management.
|
Am J Hematol
|
2008
|
1.16
|
|
30
|
Corticosteroids and increased risk of readmission after acute chest syndrome in children with sickle cell disease.
|
Pediatr Blood Cancer
|
2008
|
1.16
|
|
31
|
Hemodynamic predictors of mortality in adults with sickle cell disease.
|
Am J Respir Crit Care Med
|
2013
|
1.16
|
|
32
|
Mutations and polymorphisms in hemoglobin genes and the risk of pulmonary hypertension and death in sickle cell disease.
|
Am J Hematol
|
2008
|
1.15
|
|
33
|
Lipid levels in sickle-cell disease associated with haemolytic severity, vascular dysfunction and pulmonary hypertension.
|
Br J Haematol
|
2010
|
1.13
|
|
34
|
Sickle cell disease and nitric oxide: a paradigm shift?
|
Int J Biochem Cell Biol
|
2006
|
1.13
|
|
35
|
Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans.
|
Blood
|
2012
|
1.12
|
|
36
|
Prospective evaluation of haemoglobin oxygen saturation at rest and after exercise in paediatric sickle cell disease patients.
|
Br J Haematol
|
2009
|
1.12
|
|
37
|
Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome, hydroxyurea therapy, and lower hemolytic rates.
|
Am J Hematol
|
2012
|
1.10
|
|
38
|
Framing the research agenda for sickle cell trait: building on the current understanding of clinical events and their potential implications.
|
Am J Hematol
|
2012
|
1.10
|
|
39
|
Nitric oxide and arginine dysregulation: a novel pathway to pulmonary hypertension in hemolytic disorders.
|
Curr Mol Med
|
2008
|
1.07
|
|
40
|
Angiogenic and inflammatory markers of cardiopulmonary changes in children and adolescents with sickle cell disease.
|
PLoS One
|
2009
|
1.07
|
|
41
|
Reconstruction of Thermographic Signals to Map Perforator Vessels in Humans.
|
Quant Infrared Thermogr J
|
2012
|
1.07
|
|
42
|
Imaging flow cytometry for automated detection of hypoxia-induced erythrocyte shape change in sickle cell disease.
|
Am J Hematol
|
2014
|
1.07
|
|
43
|
Infrared imaging of nitric oxide-mediated blood flow in human sickle cell disease.
|
Microvasc Res
|
2012
|
1.06
|
|
44
|
Markers of severe vaso-occlusive painful episode frequency in children and adolescents with sickle cell anemia.
|
J Pediatr
|
2011
|
1.05
|
|
45
|
Circulating blood endothelial nitric oxide synthase contributes to the regulation of systemic blood pressure and nitrite homeostasis.
|
Arterioscler Thromb Vasc Biol
|
2013
|
1.04
|
|
46
|
Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression.
|
J Clin Invest
|
2014
|
1.03
|
|
47
|
Strategic plan for pediatric respiratory diseases research: an NHLBI working group report.
|
Proc Am Thorac Soc
|
2009
|
1.03
|
|
48
|
Current therapy of sickle cell disease.
|
Haematologica
|
2006
|
1.03
|
|
49
|
Identification and characterization of the novel centrosome-associated protein CCCAP.
|
Gene
|
2003
|
1.03
|
|
50
|
Endothelin receptor antagonists for pulmonary hypertension in adult patients with sickle cell disease.
|
Br J Haematol
|
2009
|
1.03
|
|
51
|
Sodium nitrite promotes regional blood flow in patients with sickle cell disease: a phase I/II study.
|
Br J Haematol
|
2008
|
1.03
|
|
52
|
Inhibition of PDE4 phosphodiesterase activity induces growth suppression, apoptosis, glucocorticoid sensitivity, p53, and p21(WAF1/CIP1) proteins in human acute lymphoblastic leukemia cells.
|
Blood
|
2002
|
0.99
|
|
53
|
Combination erythropoietin-hydroxyurea therapy in sickle cell disease: experience from the National Institutes of Health and a literature review.
|
Haematologica
|
2006
|
0.99
|
|
54
|
Ancestry of African Americans with sickle cell disease.
|
Blood Cells Mol Dis
|
2011
|
0.96
|
|
55
|
Severe painful vaso-occlusive crises and mortality in a contemporary adult sickle cell anemia cohort study.
|
PLoS One
|
2013
|
0.96
|
|
56
|
Fetal haemoglobin response to hydroxycarbamide treatment and sar1a promoter polymorphisms in sickle cell anaemia.
|
Br J Haematol
|
2008
|
0.96
|
|
57
|
NT-pro brain natriuretic peptide levels and the risk of death in the cooperative study of sickle cell disease.
|
Br J Haematol
|
2011
|
0.96
|
|
58
|
Sleep disturbance, depression and pain in adults with sickle cell disease.
|
BMC Psychiatry
|
2014
|
0.94
|
|
59
|
Pulmonary artery pressure and iron deficiency in patients with upregulation of hypoxia sensing due to homozygous VHL(R200W) mutation (Chuvash polycythemia).
|
Haematologica
|
2011
|
0.94
|
|
60
|
Apolipoprotein A-I and serum amyloid A plasma levels are biomarkers of acute painful episodes in patients with sickle cell disease.
|
Haematologica
|
2010
|
0.90
|
|
61
|
Genetic determinants of haemolysis in sickle cell anaemia.
|
Br J Haematol
|
2013
|
0.89
|
|
62
|
NT-proBNP as a marker of cardiopulmonary status in sickle cell anaemia in Africa.
|
Br J Haematol
|
2010
|
0.89
|
|
63
|
Leg ulcers in sickle cell disease: current patterns and practices.
|
Hemoglobin
|
2013
|
0.89
|
|
64
|
Laboratory and echocardiography markers in sickle cell patients with leg ulcers.
|
Am J Hematol
|
2011
|
0.89
|
|
65
|
Hydroxyurea-induced expression of glutathione peroxidase 1 in red blood cells of individuals with sickle cell anemia.
|
Antioxid Redox Signal
|
2010
|
0.88
|
|
66
|
Atorvastatin reduces serum cholesterol and triglycerides with limited improvement in vascular function in adults with sickle cell anemia.
|
Haematologica
|
2012
|
0.88
|
|
67
|
Hemolysis-associated hypercoagulability in sickle cell disease: the plot (and blood) thickens!
|
Haematologica
|
2008
|
0.87
|
|
68
|
Abnormal pulmonary function and associated risk factors in children and adolescents with sickle cell anemia.
|
J Pediatr Hematol Oncol
|
2014
|
0.86
|
|
69
|
Association of G6PD with lower haemoglobin concentration but not increased haemolysis in patients with sickle cell anaemia.
|
Br J Haematol
|
2010
|
0.86
|
|
70
|
Diet-induced weight loss in overweight or obese women and changes in high-density lipoprotein levels and function.
|
Obesity (Silver Spring)
|
2012
|
0.85
|
|
71
|
Clinical correlates of acute pulmonary events in children and adolescents with sickle cell disease.
|
Eur J Haematol
|
2013
|
0.84
|
|
72
|
Expression of regulatory platelet microRNAs in patients with sickle cell disease.
|
PLoS One
|
2013
|
0.84
|
|
73
|
High-density lipoprotein cholesterol efflux, nitration of apolipoprotein A-I, and endothelial function in obese women.
|
Am J Cardiol
|
2011
|
0.82
|
|
74
|
Circulating endothelial progenitor cells in adults with sickle cell disease.
|
Pulm Circ
|
2013
|
0.81
|
|
75
|
Infusion of hemolyzed red blood cells within peripheral blood stem cell grafts in patients with and without sickle cell disease.
|
Blood
|
2012
|
0.81
|
|
76
|
Thrombospondin-1 inhibits ADAMTS13 activity in sickle cell disease.
|
Haematologica
|
2013
|
0.81
|
|
77
|
A GCH1 haplotype confers sex-specific susceptibility to pain crises and altered endothelial function in adults with sickle cell anemia.
|
Am J Hematol
|
2014
|
0.81
|
|
78
|
The proteome of sickle cell disease: insights from exploratory proteomic profiling.
|
Expert Rev Proteomics
|
2010
|
0.81
|
|
79
|
Reduced sensitivity of the ferroportin Q248H mutant to physiological concentrations of hepcidin.
|
Haematologica
|
2012
|
0.79
|
|
80
|
Effects of a single sickling event on the mechanical fragility of sickle cell trait erythrocytes.
|
Hemoglobin
|
2010
|
0.79
|
|
81
|
Predictors of osteoclast activity in patients with sickle cell disease.
|
Haematologica
|
2011
|
0.79
|
|
82
|
Vasculopathy, inflammation, and blood flow in leg ulcers of patients with sickle cell anemia.
|
Am J Hematol
|
2013
|
0.79
|
|
83
|
Intravascular hemolysis and the pathophysiology of sickle cell disease.
|
J Clin Invest
|
2017
|
0.78
|
|
84
|
Characterizing non-linear dependencies among pairs of clinical variables and imaging data.
|
Conf Proc IEEE Eng Med Biol Soc
|
2012
|
0.78
|
|
85
|
TRV: a physiological biomarker in sickle cell disease.
|
Pediatr Blood Cancer
|
2011
|
0.78
|
|
86
|
A retrospective review of acupuncture use for the treatment of pain in sickle cell disease patients: descriptive analysis from a single institution.
|
Clin J Pain
|
2014
|
0.78
|
|
87
|
Anti-haemolytic effect of senicapoc and decrease in NT-proBNP in adults with sickle cell anaemia.
|
Br J Haematol
|
2011
|
0.78
|
|
88
|
Imaging flow cytometry for morphologic and phenotypic characterization of rare circulating endothelial cells.
|
Cytometry B Clin Cytom
|
2013
|
0.78
|
|
89
|
Severe pulmonary hypertension in an adolescent with sickle cell disease.
|
Am J Hematol
|
2008
|
0.77
|
|
90
|
Understanding the erythrocyte storage lesion.
|
Anesthesiology
|
2012
|
0.77
|
|
91
|
Liver stiffness increases acutely during sickle cell vaso-occlusive crisis.
|
Am J Hematol
|
2013
|
0.77
|
|
92
|
Vascular complications after splenectomy for hematologic disorders.
|
Blood
|
2009
|
0.77
|
|
93
|
A fluorescence method to detect and quantitate sterol esterification by lecithin:cholesterol acyltransferase.
|
Anal Biochem
|
2013
|
0.76
|
|
94
|
Oscillatory haematopoiesis in adults with sickle cell disease treated with hydroxycarbamide.
|
Br J Haematol
|
2014
|
0.76
|
|
95
|
Lactate dehydrogenase and hemolysis in sickle cell disease.
|
Blood
|
2013
|
0.76
|
|
96
|
Strategic plan for pediatric respiratory diseases research: an NHLBI working group report.
|
Pediatr Pulmonol
|
2009
|
0.76
|
|
97
|
Reply: Practice guideline for pulmonary hypertension in sickle cell: direct evidence needed before universal adoption.
|
Am J Respir Crit Care Med
|
2014
|
0.75
|
|
98
|
Effect of extended-release niacin on serum lipids and on endothelial function in adults with sickle cell anemia and low high-density lipoprotein cholesterol levels.
|
Am J Cardiol
|
2013
|
0.75
|