Interferon-γ signaling inhibition ameliorates angiotensin II-induced cardiac damage.

PubWeight™: 1.39‹?› | Rank: Top 5%

🔗 View Article (PMID 23108651)

Published in Hypertension on October 29, 2012

Authors

Lajos Markó1, Heda Kvakan, Joon-Keun Park, Fatimunnisa Qadri, Bastian Spallek, Katrina J Binger, Edward P Bowman, Markus Kleinewietfeld, Verena Fokuhl, Ralf Dechend, Dominik N Müller

Author Affiliations

1: Experimental and Clinical Research Center, a joint cooperation between the Charité Medical Faculty and the Max-Delbrück Center for Molecular Medicine, Berlin, Germany.

Articles citing this

Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end-organ inflammation. J Clin Invest (2015) 1.89

Inflammation, immunity, and hypertensive end-organ damage. Circ Res (2015) 1.77

DC isoketal-modified proteins activate T cells and promote hypertension. J Clin Invest (2014) 1.59

Immune activation caused by vascular oxidation promotes fibrosis and hypertension. J Clin Invest (2015) 1.55

Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase. Circ Res (2013) 1.35

Renal transporter activation during angiotensin-II hypertension is blunted in interferon-γ-/- and interleukin-17A-/- mice. Hypertension (2015) 1.24

Cardiac Fibrosis: The Fibroblast Awakens. Circ Res (2016) 1.21

The inextricable role of the kidney in hypertension. J Clin Invest (2014) 1.05

The immune system in hypertension. Trans Am Clin Climatol Assoc (2014) 1.05

The immune system in hypertension. Adv Physiol Educ (2014) 1.03

Tumor necrosis factor-α produced in the kidney contributes to angiotensin II-dependent hypertension. Hypertension (2014) 0.99

Immune Mechanisms in Arterial Hypertension. J Am Soc Nephrol (2015) 0.94

Left Ventricular T-Cell Recruitment Contributes to the Pathogenesis of Heart Failure. Circ Heart Fail (2015) 0.93

Role of T lymphocytes in hypertension. Curr Opin Pharmacol (2014) 0.93

CD70 Exacerbates Blood Pressure Elevation and Renal Damage in Response to Repeated Hypertensive Stimuli. Circ Res (2016) 0.91

Activation of NAD(P)H oxidase by tryptophan-derived 3-hydroxykynurenine accelerates endothelial apoptosis and dysfunction in vivo. Circ Res (2013) 0.89

Activation of Human T Cells in Hypertension: Studies of Humanized Mice and Hypertensive Humans. Hypertension (2016) 0.89

Role of chemokine RANTES in the regulation of perivascular inflammation, T-cell accumulation, and vascular dysfunction in hypertension. FASEB J (2016) 0.87

Sodium chloride, SGK1, and Th17 activation. Pflugers Arch (2014) 0.86

Role of Axl in early kidney inflammation and progression of salt-dependent hypertension. Hypertension (2013) 0.85

Interleukin-2/Anti-Interleukin-2 Immune Complex Expands Regulatory T Cells and Reduces Angiotensin II-Induced Aortic Stiffening. Int J Hypertens (2014) 0.83

Gut Microbiota Promote Angiotensin II-Induced Arterial Hypertension and Vascular Dysfunction. J Am Heart Assoc (2016) 0.81

Perivascular adipose tissue inflammation in vascular disease. Br J Pharmacol (2017) 0.79

Novel Immune Mechanisms in Hypertension and Cardiovascular Risk. Curr Cardiovasc Risk Rep (2017) 0.77

Time course of cardiac inflammation during nitric oxide synthase inhibition in SHR: impact of prior transient ACE inhibition. Hypertens Res (2015) 0.77

Canonical correlation analysis for gene-based pleiotropy discovery. PLoS Comput Biol (2014) 0.77

Antibody therapy can enhance AngiotensinII-induced myocardial fibrosis. Fibrogenesis Tissue Repair (2014) 0.77

Linking inflammation and hypertension via LNK/SH2B3. Curr Opin Nephrol Hypertens (2016) 0.77

Interferon regulatory factors in heart: stress response beyond inflammation. Hypertension (2014) 0.76

Macrophage heterogeneity and renin-angiotensin system disorders. Pflugers Arch (2017) 0.75

Synaptopodin Limits TRPC6 Podocyte Surface Expression and Attenuates Proteinuria. J Am Soc Nephrol (2016) 0.75

Pulmonary fibrosis in a mouse model of sarcoid granulomatosis induced by booster challenge with Propionibacterium acnes. Oncotarget (2016) 0.75

Expression of Transglutaminase in Foreskin of Children with Balanitis Xerotica Obliterans. Int J Mol Sci (2016) 0.75

Targeting cytokine signaling in salt-sensitive hypertension. Am J Physiol Renal Physiol (2016) 0.75

Interactions of hyperhomocysteinemia and T cell immunity in causation of hypertension. Can J Physiol Pharmacol (2016) 0.75

Articles by these authors

Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat Immunol (2007) 12.76

Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression. Blood (2007) 6.03

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category. J Exp Med (2008) 5.25

Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection. N Engl J Med (2005) 4.84

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells. Nature (2013) 4.57

Induction and molecular signature of pathogenic TH17 cells. Nat Immunol (2012) 4.43

IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4-CD8- entheseal resident T cells. Nat Med (2012) 4.38

Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells. J Invest Dermatol (2008) 4.18

Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nat Med (2009) 4.07

CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat Med (2002) 4.02

IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J Exp Med (2006) 3.38

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways. Nat Neurosci (2013) 3.11

Hematopoietic stem cells are uniquely selective in their migratory response to chemokines. J Exp Med (2002) 2.96

Immunosuppressive treatment protects against angiotensin II-induced renal damage. Am J Pathol (2002) 2.50

Signal transducer and activator of transcription 3 is required for myocardial capillary growth, control of interstitial matrix deposition, and heart protection from ischemic injury. Circ Res (2004) 2.45

Long-term space flight simulation reveals infradian rhythmicity in human Na(+) balance. Cell Metab (2013) 2.38

Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage. Circ Res (2007) 2.25

The effect of immune factors, tumor necrosis factor-alpha, and agonistic autoantibodies to the angiotensin II type I receptor on soluble fms-like tyrosine-1 and soluble endoglin production in response to hypertension during pregnancy. Am J Hypertens (2010) 2.23

Dysregulation of the circulating and tissue-based renin-angiotensin system in preeclampsia. Hypertension (2007) 2.17

AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase. Circulation (2003) 2.15

Prorenin receptor is essential for podocyte autophagy and survival. J Am Soc Nephrol (2011) 2.04

Growth retardation and altered autonomic control in mice lacking brain serotonin. Proc Natl Acad Sci U S A (2009) 2.01

Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive enhancer binding protein/vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats. Hypertension (2010) 2.01

Hypertension in response to autoantibodies to the angiotensin II type I receptor (AT1-AA) in pregnant rats: role of endothelin-1. Hypertension (2009) 2.00

RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing. Nat Med (2012) 1.97

CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells. J Clin Invest (2003) 1.93

Immune cells control skin lymphatic electrolyte homeostasis and blood pressure. J Clin Invest (2013) 1.92

Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats. Hypertension (2005) 1.89

Dysfunction of dysferlin-deficient hearts. J Mol Med (Berl) (2007) 1.89

Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of {omega}-3 fatty acids. J Biol Chem (2010) 1.83

Involvement of functional autoantibodies against vascular receptors in systemic sclerosis. Ann Rheum Dis (2010) 1.83

Role of "Western diet" in inflammatory autoimmune diseases. Curr Allergy Asthma Rep (2014) 1.79

Regulatory T cells ameliorate angiotensin II-induced cardiac damage. Circulation (2009) 1.77

Agonistic autoantibodies to the AT1 receptor in a transgenic rat model of preeclampsia. Hypertension (2005) 1.74

Autoantibodies to the angiotensin type I receptor in response to placental ischemia and tumor necrosis factor alpha in pregnant rats. Hypertension (2008) 1.65

Differential expression of AT1 receptors in the pituitary and adrenal gland of SHR and WKY. Hypertension (2003) 1.61

Leptin regulates ACE activity in mice. J Mol Med (Berl) (2010) 1.59

Differential effect of ischaemic preconditioning on mobilisation and recruitment of haematopoietic and mesenchymal stem cells in porcine myocardial ischaemia-reperfusion. Thromb Haemost (2010) 1.58

Agonistic angiotensin II type 1 receptor autoantibodies in postpartum women with a history of preeclampsia. Hypertension (2007) 1.56

Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system. Proc Natl Acad Sci U S A (2009) 1.56

Regulation of myeloid cell function through the CD200 receptor. J Immunol (2006) 1.56

Elevated blood pressure and heart rate in human renin receptor transgenic rats. Hypertension (2006) 1.51

23Na magnetic resonance imaging-determined tissue sodium in healthy subjects and hypertensive patients. Hypertension (2013) 1.51

Agonistic antibodies directed at the angiotensin II, AT1 receptor in preeclampsia. J Soc Gynecol Investig (2006) 1.49

Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide. Hypertension (2008) 1.48

Vitronectin concentrations predict risk in patients undergoing coronary stenting. Circ Cardiovasc Interv (2008) 1.44

Oxidative stress and preeclampsia: rationale for antioxidant clinical trials. Hypertension (2004) 1.44

Sodium chloride inhibits the suppressive function of FOXP3+ regulatory T cells. J Clin Invest (2015) 1.43

Central control of fever and female body temperature by RANKL/RANK. Nature (2009) 1.42

Cardiac hypertrophy and fibrosis in chronic L-NAME-treated AT2 receptor-deficient mice. J Hypertens (2004) 1.39

Prorenin is the endogenous agonist of the (pro)renin receptor. Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing the human (pro)renin receptor. J Hypertens (2007) 1.35

Hypertension in response to placental ischemia during pregnancy: role of B lymphocytes. Hypertension (2011) 1.34

Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cells. Circulation (2004) 1.32

High salt reduces the activation of IL-4- and IL-13-stimulated macrophages. J Clin Invest (2015) 1.30

(23)Na magnetic resonance imaging of tissue sodium. Hypertension (2011) 1.29

Acute administration of recombinant Angiopoietin-1 ameliorates multiple-organ dysfunction syndrome and improves survival in murine sepsis. Cytokine (2011) 1.29

Activating auto-antibodies against the AT1 receptor in preeclampsia. Autoimmun Rev (2005) 1.27

The synthetic tie2 agonist peptide vasculotide protects against vascular leakage and reduces mortality in murine abdominal sepsis. Crit Care (2011) 1.25

Interleukin-17A upregulates receptor activator of NF-kappaB on osteoclast precursors. Arthritis Res Ther (2010) 1.24

Statins attenuate ischemia-reperfusion injury by inducing heme oxygenase-1 in infiltrating macrophages. Am J Pathol (2007) 1.24

Hypertension in response to AT1-AA: role of reactive oxygen species in pregnancy-induced hypertension. Am J Hypertens (2011) 1.24

Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant rats. Hypertension (2011) 1.24

Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage. Circulation (2005) 1.23

Microbial reprogramming inhibits Western diet-associated obesity. PLoS One (2013) 1.21

Immunization with Staphylococcus aureus iron regulated surface determinant B (IsdB) confers protection via Th17/IL17 pathway in a murine sepsis model. Hum Vaccin Immunother (2012) 1.20

Cofilin-1 inactivation leads to proteinuria--studies in zebrafish, mice and humans. PLoS One (2010) 1.20

Parietal epithelia cells in the urine as a marker of disease activity in glomerular diseases. Nephrol Dial Transplant (2008) 1.19

The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling. J Am Soc Nephrol (2008) 1.19

Potential relevance of alpha(1)-adrenergic receptor autoantibodies in refractory hypertension. PLoS One (2008) 1.19

IL-17-mediated oxidative stress is an important stimulator of AT1-AA and hypertension during pregnancy. Am J Physiol Regul Integr Comp Physiol (2012) 1.18

New aspects in the pathophysiology of preeclampsia. J Am Soc Nephrol (2004) 1.17

Activating autoantibodies to the angiotensin II type I receptor play an important role in mediating hypertension in response to adoptive transfer of CD4+ T lymphocytes from placental ischemic rats. Am J Physiol Regul Integr Comp Physiol (2012) 1.17

Neutralization or absence of the interleukin-23 pathway does not compromise immunity to mycobacterial infection. Infect Immun (2006) 1.17

A role of the (pro)renin receptor in neuronal cell differentiation. Am J Physiol Regul Integr Comp Physiol (2009) 1.16

Prevalence of agonistic autoantibodies against the angiotensin II type 1 receptor and soluble fms-like tyrosine kinase 1 in a gestational age-matched case study. Hypertension (2008) 1.16

A recently evolved novel trophoblast-enriched secreted form of fms-like tyrosine kinase-1 variant is up-regulated in hypoxia and preeclampsia. J Clin Endocrinol Metab (2009) 1.16

Diminished loss of proteoglycans and lack of albuminuria in protein kinase C-alpha-deficient diabetic mice. Diabetes (2004) 1.15

Postischemic acute renal failure is reduced by short-term statin treatment in a rat model. J Am Soc Nephrol (2002) 1.15