Regulation of bile acid synthesis. IV. Interrelationship between cholesterol and bile acid biosynthesis pathways.

PubWeight™: 0.83‹?›

🔗 View Article (PMID 2313206)

Published in J Lipid Res on January 01, 1990

Authors

W M Pandak1, D M Heuman, P B Hylemon, Z R Vlahcevic

Author Affiliations

1: Department of Medicine, Medical College of Virginia, Richmond 23298.

Articles by these authors

Long-term outcome of medical and surgical therapies for gastroesophageal reflux disease: follow-up of a randomized controlled trial. JAMA (2001) 8.40

Independent regulation of hexose catabolizing enzymes and glucose transport activity in Pseudomonas aeruginosa. Biochem Biophys Res Commun (1972) 3.63

Diminished bile acid pool size in patients with gallstones. Gastroenterology (1970) 2.95

Randomised clinical trial: Lactobacillus GG modulates gut microbiome, metabolome and endotoxemia in patients with cirrhosis. Aliment Pharmacol Ther (2014) 2.88

Cyclic adenosine 3',5'-monophosphate levels and activities of adenylate cyclase and cyclic adenosine 3',5'-monophosphate phosphodiesterase in Pseudomonas and Bacteroides. J Bacteriol (1977) 2.49

Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway. J Biol Chem (2001) 2.37

Small intestinal neoplasms. J Clin Gastroenterol (2001) 2.19

Comparison of lactulose and neomycin in the treatment of chronic portal-systemic encephalopathy. A double blind controlled trial. Gastroenterology (1977) 2.10

Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis. Mol Biol Cell (2001) 1.76

Evidence against the presence of cyclic AMP and related enzymes in selected strains of Bacteroides fragilis. Biochem Biophys Res Commun (1974) 1.60

Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients. J Clin Invest (1989) 1.59

Multicompartmental analysis of cholesterol metabolism in man. Characterization of the hepatic bile acid and biliary cholesterol precursor sites. J Clin Invest (1978) 1.59

Bile acid pools, kinetics and biliary lipid composition before and after cholecystectomy. N Engl J Med (1973) 1.56

Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat. Gastroenterology (1997) 1.54

Sequencing and expression of a gene encoding a bile acid transporter from Eubacterium sp. strain VPI 12708. J Bacteriol (1996) 1.52

Transport and catabolism of D-fructose by Spirillum itersomii. J Bacteriol (1974) 1.49

Preferential utilization of free cholesterol from high-density lipoproteins for biliary cholesterol secretion in man. Science (1978) 1.47

Bile acid induction specificity of 7 alpha-dehydroxylase activity in an intestinal Eubacterium species. Steroids (1980) 1.45

Hepatocellular protein kinase C activation by bile acids: implications for regulation of cholesterol 7 alpha-hydroxylase. Am J Physiol (1996) 1.45

Identification and characterization of a bile acid 7alpha-dehydroxylation operon in Clostridium sp. strain TO-931, a highly active 7alpha-dehydroxylating strain isolated from human feces. Appl Environ Microbiol (2000) 1.41

Cloning and sequencing of a bile acid-inducible operon from Eubacterium sp. strain VPI 12708. J Bacteriol (1990) 1.41

Bile-rich duodenal fluid as an indicator of biliary lipid composition and its applicability to detection of lithogenic bile. Am J Dig Dis (1971) 1.39

7 alpha-dehydroxylating bacteria enhance deoxycholic acid input and cholesterol saturation of bile in patients with gallstones. Gastroenterology (1996) 1.39

Purification and characterization of bile salt hydrolase from Clostridium perfringens. J Lipid Res (1988) 1.35

Significance of the liver in the production of lithogenic bile in man. Gastroenterology (1970) 1.35

Characterization of the baiH gene encoding a bile acid-inducible NADH:flavin oxidoreductase from Eubacterium sp. strain VPI 12708. J Bacteriol (1993) 1.31

Regulation of cholesterol 7 alpha-hydroxylase mRNA and transcriptional activity by taurocholate and cholesterol in the chronic biliary diverted rat. J Biol Chem (1991) 1.28

7alpha-Dehydroxylation of cholic acid and chenodeoxycholic acid by Clostridium leptum. J Lipid Res (1979) 1.26

Purification and characterization of bile salt hydrolase from Bacteroides fragilis subsp. fragilis. Biochim Biophys Acta (1976) 1.25

PROMIS computerised adaptive tests are dynamic instruments to measure health-related quality of life in patients with cirrhosis. Aliment Pharmacol Ther (2011) 1.22

Biosynthesis of a novel bile acid nucleotide and mechanism of 7 alpha-dehydroxylation by an intestinal Eubacterium species. J Biol Chem (1987) 1.22

Cofactor requiremets for 7 alpha-dehydroxylation of cholic and chenodeoxycholic acid in cell extracts of the intestinal anaerobic bacterium, Eubacterium species V.P.I. 13708. J Lipid Res (1981) 1.22

Modified plasmid isolation method for Clostridium perfringens and Clostridium absonum. Appl Environ Microbiol (1986) 1.22

Kinetics and pool size of primary bile acids in man. Gastroenterology (1971) 1.20

Hormonal regulation of cholesterol 7 alpha-hydroxylase mRNA levels and transcriptional activity in primary rat hepatocyte cultures. J Biol Chem (1992) 1.19

Conjugates of ursodeoxycholate protect against cholestasis and hepatocellular necrosis caused by more hydrophobic bile salts. In vivo studies in the rat. Gastroenterology (1991) 1.19

Relationship of bile acid pool size to biliary lipid excretion and the formation of lithogenic bile in man. Gastroenterology (1971) 1.16

Relationship of bile acid pool size to the formation of lithogenic bile in female Indians of the southwest. Gastroenterology (1972) 1.16

Immunochemical evidence for induction of a common form of hepatic cytochrome P-450 in rats treated with pregnenolone-16 alpha-carbonitrile or other steroidal or non-steroidal agents. Mol Pharmacol (1982) 1.16

A role for both Ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes. Mol Biol Cell (2000) 1.16

Uptake and incorporation of glucose and mannose by whole cells of Bacteroides thetaiotaomicron. Appl Environ Microbiol (1977) 1.16

Evidence for high-density lipoprotein-free cholesterol as the primary precursor for bile-acid synthesis in man. Surgery (1978) 1.15

Assessment of fecal bacteria with bile acid 7 alpha-dehydroxylating activity for the presence of bai-like genes. Appl Environ Microbiol (1997) 1.13

The bile acid-inducible baiB gene from Eubacterium sp. strain VPI 12708 encodes a bile acid-coenzyme A ligase. J Bacteriol (1992) 1.13

Synthesis of guanosine tetra- and pentaphosphates by the obligately anaerobic bacterium Bacteroides thetaiotaomicron in response to molecular oxygen. J Bacteriol (1979) 1.12

Multiple forms of 7-alpha-hydroxysteroid dehydrogenase in selected strains of Bacteroides fragilis. J Bacteriol (1975) 1.10

Evidence for a multigene family involved in bile acid 7-dehydroxylation in Eubacterium sp. strain VPI 12708. J Bacteriol (1988) 1.09

Bile acid biotransformation rates of selected gram-positive and gram-negative intestinal anaerobic bacteria. Biochem Biophys Res Commun (1976) 1.09

Failure of intravenous infusion of taurocholate to down-regulate cholesterol 7 alpha-hydroxylase in rats with biliary fistulas. Gastroenterology (1995) 1.08

Regulation of bile acid synthesis. III. Correlation between biliary bile salt hydrophobicity index and the activities of enzymes regulating cholesterol and bile acid synthesis in the rat. J Lipid Res (1989) 1.07

Bile acid metabolism by fresh human colonic contents: a comparison of caecal versus faecal samples. Gut (2001) 1.06

HPLC purification and preparation of antibodies to cholic acid-inducible polypeptides from Eubacterium sp. V.P.I. 12708. J Lipid Res (1984) 1.06

Repression of cholesterol 7 alpha-hydroxylase transcription by bile acids is mediated through protein kinase C in primary cultures of rat hepatocytes. J Lipid Res (1995) 1.05

Predictors of the recurrence of hepatic encephalopathy in lactulose-treated patients. Aliment Pharmacol Ther (2010) 1.05

Activation of protein kinase C alpha and delta by bile acids: correlation with bile acid structure and diacylglycerol formation. J Lipid Res (1997) 1.05

Mechanism of secretion of biliary lipids. I. Role of bile canalicular and microsomal membranes in the synthesis and transport of biliary lecithin and cholesterol. J Clin Invest (1975) 1.04

Development of a new shuttle plasmid system for Escherichia coli and Clostridium perfringens. Appl Environ Microbiol (1988) 1.04

Molecular cloning of bile acid 7-dehydroxylase from Eubacterium sp. strain VPI 12708. J Bacteriol (1987) 1.04

Expression and characterization of a C24 bile acid 7 alpha-dehydratase from Eubacterium sp. strain VPI 12708 in Escherichia coli. J Lipid Res (1996) 1.04

Conjugates of ursodeoxycholate protect against cytotoxicity of more hydrophobic bile salts: in vitro studies in rat hepatocytes and human erythrocytes. Hepatology (1991) 1.04

Mechanism of secretion of biliary lipids: role of a microtubular system in hepatocellular transport of biliary lipids in the rat. Gastroenterology (1978) 1.04

Molecular cloning of a gene encoding a 45,000-dalton polypeptide associated with bile acid 7-dehydroxylation in Eubacterium sp. strain VPI 12708. J Bacteriol (1988) 1.04

A proposed nomenclature for bile acids. J Lipid Res (1992) 1.03

Hepatitis B virus X protein increases expression of p21(Cip-1/WAF1/MDA6) and p27(Kip-1) in primary mouse hepatocytes, leading to reduced cell cycle progression. Hepatology (2001) 1.03

Induction of sodium-dependent bile acid transporter messenger RNA, protein, and activity in rat ileum by cholic acid. Gastroenterology (1997) 1.02

Nucleotide sequence and regulation of a gene involved in bile acid 7-dehydroxylation by Eubacterium sp. strain VPI 12708. J Bacteriol (1988) 1.02

Multiple copies of a bile acid-inducible gene in Eubacterium sp. strain VPI 12708. J Bacteriol (1990) 1.02

Bile acid metabolism in patients with cirrhosis. II. Cholic and chenodeoxycholic acid metabolism. Gastroenterology (1972) 1.01

Abnormal metabolism of secondary bile acids in patients with cirrhosis. Gut (1970) 1.01

Expression of sterol 12alpha-hydroxylase alters bile acid pool composition in primary rat hepatocytes and in vivo. Gastroenterology (2001) 0.99

Proton pump inhibitors are associated with a high rate of serious infections in veterans with decompensated cirrhosis. Aliment Pharmacol Ther (2012) 0.99

Characterization of a NADH:flavin oxidoreductase induced by cholic acid in a 7 alpha-dehydroxylating intestinal Eubacterium species. Biochim Biophys Acta (1980) 0.98

An in vivo evaluation of the quantitative significance of several potential pathways to cholic and chenodeoxycholic acids from cholesterol in man. J Lipid Res (1980) 0.98

Regulation of bile acid 7-dehydroxylase activity by NAD+ and NADH in cell extracts of Eubacterium species V.P.I. 12708. J Lipid Res (1983) 0.98

Mode of action of steroid desmolase and reductases synthesized by Clostridium "scindens" (formerly Clostridium strain 19). J Lipid Res (1984) 0.98

Cholic acid synthesis as an index of the severity of liver disease in man. Gut (1973) 0.98

Detection of the steroidogenic acute regulatory protein, StAR, in human liver cells. Biochim Biophys Acta (2005) 0.98

Bile acid metabolism in patients with cirrhosis. I. Kinetic aspects of cholic acid metabolism. Gastroenterology (1971) 0.97

Healing of benign gastric ulcer: comparison of cimetidine and placebo in the United States. Ann Intern Med (1985) 0.97

Hepatoprotective properties of ursodeoxycholic acid. Gastroenterology (1993) 0.97

Regulation of sterol 12alpha-hydroxylase and cholic acid biosynthesis in the rat. Gastroenterology (2000) 0.97

Hep G2 cells: a model for studies on regulation of human cholesterol 7alpha-hydroxylase at the molecular level. Am J Physiol (1996) 0.97

Regulation of sterol 27-hydroxylase and an alternative pathway of bile acid biosynthesis in primary cultures of rat hepatocytes. J Steroid Biochem Mol Biol (1996) 0.97

Regulation of bile acid synthesis. II. Effect of bile acid feeding on enzymes regulating hepatic cholesterol and bile acid synthesis in the rat. Hepatology (1988) 0.96

Suitability of primary monolayer cultures of adult rat hepatocytes for studies of cholesterol and bile acid metabolism. J Biol Chem (1985) 0.95