Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Characterization of the reconstructed 1918 Spanish influenza pandemic virus.
|
Science
|
2005
|
17.19
|
2
|
Large-scale sequencing of human influenza reveals the dynamic nature of viral genome evolution.
|
Nature
|
2005
|
11.99
|
3
|
Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness.
|
J Infect Dis
|
2008
|
11.01
|
4
|
The genomic and epidemiological dynamics of human influenza A virus.
|
Nature
|
2008
|
10.26
|
5
|
Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus.
|
Science
|
2006
|
10.04
|
6
|
Structure of the uncleaved human H1 hemagglutinin from the extinct 1918 influenza virus.
|
Science
|
2004
|
6.70
|
7
|
Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus.
|
Nature
|
2006
|
6.46
|
8
|
Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities.
|
J Mol Biol
|
2005
|
6.17
|
9
|
Whole-genome analysis of human influenza A virus reveals multiple persistent lineages and reassortment among recent H3N2 viruses.
|
PLoS Biol
|
2005
|
5.48
|
10
|
Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice.
|
J Virol
|
2005
|
4.72
|
11
|
A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity.
|
J Virol
|
2005
|
4.71
|
12
|
Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza.
|
Proc Natl Acad Sci U S A
|
2002
|
4.26
|
13
|
The evolutionary genetics and emergence of avian influenza viruses in wild birds.
|
PLoS Pathog
|
2008
|
4.17
|
14
|
Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus.
|
Proc Natl Acad Sci U S A
|
2004
|
4.00
|
15
|
Pulmonary pathologic findings of fatal 2009 pandemic influenza A/H1N1 viral infections.
|
Arch Pathol Lab Med
|
2010
|
3.91
|
16
|
Stochastic processes are key determinants of short-term evolution in influenza a virus.
|
PLoS Pathog
|
2006
|
3.82
|
17
|
The persistent legacy of the 1918 influenza virus.
|
N Engl J Med
|
2009
|
3.58
|
18
|
Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918.
|
PLoS Pathog
|
2008
|
3.25
|
19
|
Evidence of an absence: the genetic origins of the 1918 pandemic influenza virus.
|
Nat Rev Microbiol
|
2004
|
3.19
|
20
|
The origin of the 1918 pandemic influenza virus: a continuing enigma.
|
J Gen Virol
|
2003
|
2.98
|
21
|
Pathology of human influenza revisited.
|
Vaccine
|
2008
|
2.71
|
22
|
Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus.
|
J Virol
|
2004
|
2.67
|
23
|
Novel origin of the 1918 pandemic influenza virus nucleoprotein gene.
|
J Virol
|
2004
|
2.55
|
24
|
1918 influenza pandemic caused by highly conserved viruses with two receptor-binding variants.
|
Emerg Infect Dis
|
2003
|
2.32
|
25
|
Pause on avian flu transmission research.
|
Science
|
2012
|
2.24
|
26
|
Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus.
|
Proc Natl Acad Sci U S A
|
2002
|
2.21
|
27
|
Lung pathology of severe acute respiratory syndrome (SARS): a study of 8 autopsy cases from Singapore.
|
Hum Pathol
|
2003
|
2.08
|
28
|
Characterization of the 1918 "Spanish" influenza virus matrix gene segment.
|
J Virol
|
2002
|
2.05
|
29
|
Multidrug-resistant 2009 pandemic influenza A(H1N1) viruses maintain fitness and transmissibility in ferrets.
|
J Infect Dis
|
2010
|
2.03
|
30
|
Pandemic influenza: an inconvenient mutation.
|
Science
|
2009
|
2.00
|
31
|
Age- and sex-specific mortality associated with the 1918-1919 influenza pandemic in Kentucky.
|
J Infect Dis
|
2012
|
1.95
|
32
|
Detection of novel (swine origin) H1N1 influenza A virus by quantitative real-time reverse transcription-PCR.
|
J Clin Microbiol
|
2009
|
1.93
|
33
|
Rapid selection of oseltamivir- and peramivir-resistant pandemic H1N1 virus during therapy in 2 immunocompromised hosts.
|
Clin Infect Dis
|
2010
|
1.89
|
34
|
Different evolutionary trajectories of European avian-like and classical swine H1N1 influenza A viruses.
|
J Virol
|
2009
|
1.79
|
35
|
Engineering H5N1 avian influenza viruses to study human adaptation.
|
Nature
|
2012
|
1.74
|
36
|
Historical thoughts on influenza viral ecosystems, or behold a pale horse, dead dogs, failing fowl, and sick swine.
|
Influenza Other Respir Viruses
|
2010
|
1.68
|
37
|
Autopsy series of 68 cases dying before and during the 1918 influenza pandemic peak.
|
Proc Natl Acad Sci U S A
|
2011
|
1.67
|
38
|
Imaging findings in a fatal case of pandemic swine-origin influenza A (H1N1).
|
AJR Am J Roentgenol
|
2009
|
1.63
|
39
|
Homologous recombination is very rare or absent in human influenza A virus.
|
J Virol
|
2008
|
1.63
|
40
|
1917 avian influenza virus sequences suggest that the 1918 pandemic virus did not acquire its hemagglutinin directly from birds.
|
J Virol
|
2002
|
1.60
|
41
|
Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomain.
|
PLoS Pathog
|
2012
|
1.55
|
42
|
Pandemic influenza's 500th anniversary.
|
Clin Infect Dis
|
2010
|
1.55
|
43
|
Pandemic and seasonal influenza: therapeutic challenges.
|
Drug Discov Today
|
2008
|
1.54
|
44
|
Role of sialic acid binding specificity of the 1918 influenza virus hemagglutinin protein in virulence and pathogenesis for mice.
|
J Virol
|
2009
|
1.53
|
45
|
Pandemic swine-origin H1N1 influenza A virus isolates show heterogeneous virulence in macaques.
|
J Virol
|
2010
|
1.47
|
46
|
Synthetic viruses: a new opportunity to understand and prevent viral disease.
|
Nat Biotechnol
|
2009
|
1.47
|
47
|
Recent human influenza A/H3N2 virus evolution driven by novel selection factors in addition to antigenic drift.
|
J Infect Dis
|
2009
|
1.44
|
48
|
Examining the hemagglutinin subtype diversity among wild duck-origin influenza A viruses using ethanol-fixed cloacal swabs and a novel RT-PCR method.
|
Virology
|
2008
|
1.42
|
49
|
Pandemic influenza: certain uncertainties.
|
Rev Med Virol
|
2011
|
1.39
|
50
|
An early 'classical' swine H1N1 influenza virus shows similar pathogenicity to the 1918 pandemic virus in ferrets and mice.
|
Virology
|
2009
|
1.37
|
51
|
The 1918 influenza pandemic: lessons for 2009 and the future.
|
Crit Care Med
|
2010
|
1.36
|
52
|
Lethal synergism of 2009 pandemic H1N1 influenza virus and Streptococcus pneumoniae coinfection is associated with loss of murine lung repair responses.
|
MBio
|
2011
|
1.36
|
53
|
Rapid selection of a transmissible multidrug-resistant influenza A/H3N2 virus in an immunocompromised host.
|
J Infect Dis
|
2010
|
1.29
|
54
|
Reassortment and mutation of the avian influenza virus polymerase PA subunit overcome species barriers.
|
J Virol
|
2011
|
1.28
|
55
|
Evolutionary conservation of the PA-X open reading frame in segment 3 of influenza A virus.
|
J Virol
|
2012
|
1.27
|
56
|
Pandemic influenza viruses--hoping for the road not taken.
|
N Engl J Med
|
2013
|
1.26
|
57
|
Prior infection with classical swine H1N1 influenza viruses is associated with protective immunity to the 2009 pandemic H1N1 virus.
|
Influenza Other Respir Viruses
|
2010
|
1.25
|
58
|
The ability of pandemic influenza virus hemagglutinins to induce lower respiratory pathology is associated with decreased surfactant protein D binding.
|
Virology
|
2011
|
1.25
|
59
|
The 2009 H1N1 pandemic influenza virus: what next?
|
MBio
|
2010
|
1.22
|
60
|
H7N9 avian influenza A virus and the perpetual challenge of potential human pandemicity.
|
MBio
|
2013
|
1.20
|
61
|
The PB2-E627K mutation attenuates viruses containing the 2009 H1N1 influenza pandemic polymerase.
|
MBio
|
2010
|
1.18
|
62
|
Protection against a lethal H5N1 influenza challenge by intranasal immunization with virus-like particles containing 2009 pandemic H1N1 neuraminidase in mice.
|
Virology
|
2012
|
1.16
|
63
|
Understanding influenza backward.
|
JAMA
|
2009
|
1.15
|
64
|
Preventing pandemics: The fight over flu.
|
Nature
|
2012
|
1.10
|
65
|
Overlapping signals for translational regulation and packaging of influenza A virus segment 2.
|
Nucleic Acids Res
|
2011
|
1.09
|
66
|
High-throughput RNA sequencing of a formalin-fixed, paraffin-embedded autopsy lung tissue sample from the 1918 influenza pandemic.
|
J Pathol
|
2013
|
1.09
|
67
|
Transmission studies resume for avian flu.
|
Science
|
2013
|
1.07
|
68
|
Heading off an influenza pandemic.
|
Science
|
2005
|
1.04
|
69
|
Changes in microRNA and mRNA expression with differentiation of human bronchial epithelial cells.
|
Am J Respir Cell Mol Biol
|
2013
|
1.03
|
70
|
Immunization with 1976 swine H1N1- or 2009 pandemic H1N1-inactivated vaccines protects mice from a lethal 1918 influenza infection.
|
Influenza Other Respir Viruses
|
2011
|
1.02
|
71
|
Molecular basis for broad neuraminidase immunity: conserved epitopes in seasonal and pandemic H1N1 as well as H5N1 influenza viruses.
|
J Virol
|
2013
|
1.02
|
72
|
Methods for molecular surveillance of influenza.
|
Expert Rev Anti Infect Ther
|
2010
|
0.99
|
73
|
The natural history of influenza infection in the severely immunocompromised vs nonimmunocompromised hosts.
|
Clin Infect Dis
|
2013
|
0.97
|
74
|
1918 influenza, a puzzle with missing pieces.
|
Emerg Infect Dis
|
2012
|
0.95
|
75
|
Effect of preservative on recoverable RT-PCR amplicon length from influenza A virus in bird feces.
|
Avian Dis
|
2007
|
0.95
|
76
|
Human H-ficolin inhibits replication of seasonal and pandemic influenza A viruses.
|
J Immunol
|
2012
|
0.95
|
77
|
The relationship between encephalitis lethargica and influenza: a critical analysis.
|
J Neurovirol
|
2008
|
0.93
|
78
|
Obese mice have increased morbidity and mortality compared to non-obese mice during infection with the 2009 pandemic H1N1 influenza virus.
|
Influenza Other Respir Viruses
|
2011
|
0.92
|
79
|
Successful explantation of a ventricular assist device following fulminant influenza type A-associated myocarditis.
|
J Heart Lung Transplant
|
2002
|
0.90
|
80
|
Analysis by single-gene reassortment demonstrates that the 1918 influenza virus is functionally compatible with a low-pathogenicity avian influenza virus in mice.
|
J Virol
|
2012
|
0.89
|
81
|
An avian outbreak associated with panzootic equine influenza in 1872: an early example of highly pathogenic avian influenza?
|
Influenza Other Respir Viruses
|
2010
|
0.89
|
82
|
Ewing sarcoma family of tumors in unusual sites: confirmation by rt-PCR.
|
Pediatr Dev Pathol
|
2006
|
0.88
|
83
|
In vivo evaluation of pathogenicity and transmissibility of influenza A(H1N1)pdm09 hemagglutinin receptor binding domain 222 intrahost variants isolated from a single immunocompromised patient.
|
Virology
|
2012
|
0.87
|
84
|
Global rinderpest eradication: lessons learned and why humans should celebrate too.
|
J Infect Dis
|
2011
|
0.86
|
85
|
SARS-CoV virus-host interactions and comparative etiologies of acute respiratory distress syndrome as determined by transcriptional and cytokine profiling of formalin-fixed paraffin-embedded tissues.
|
J Interferon Cytokine Res
|
2006
|
0.85
|
86
|
The role of radiology in influenza: novel H1N1 and lessons learned from the 1918 pandemic.
|
J Am Coll Radiol
|
2010
|
0.85
|
87
|
Serial analysis of gene expression in murine fetal thymocyte cell lines.
|
Int Immunol
|
2002
|
0.82
|
88
|
Phylogenetic analysis of low pathogenicity H5N1 and H7N3 influenza A virus isolates recovered from sentinel, free flying, wild mallards at one study site during 2006.
|
Virology
|
2011
|
0.81
|
89
|
Influenza in pregnancy.
|
Influenza Other Respir Viruses
|
2012
|
0.81
|
90
|
Rapid sequencing of influenza A virus vRNA, cRNA and mRNA non-coding regions.
|
J Virol Methods
|
2013
|
0.80
|
91
|
Detection of SYT-SSX fusion transcripts in archival synovial sarcomas by real-time reverse transcriptase-polymerase chain reaction.
|
J Mol Diagn
|
2002
|
0.80
|
92
|
HASP server: a database and structural visualization platform for comparative models of influenza A hemagglutinin proteins.
|
BMC Bioinformatics
|
2013
|
0.78
|
93
|
Eyewitness accounts of the 1510 influenza pandemic in Europe.
|
Lancet
|
2010
|
0.78
|
94
|
Fatal 1918 pneumonia case complicated by erythrocyte sickling.
|
Emerg Infect Dis
|
2010
|
0.78
|
95
|
Influenza and the origins of The Philips Collection, Washington, DC.
|
Emerg Infect Dis
|
2006
|
0.77
|
96
|
Characterization of the noncoding regions of the 1918 influenza A H1N1 virus.
|
J Virol
|
2013
|
0.77
|
97
|
Flu season: An interview with Jeffery K. Taubenberger, Chief of the Viral Pathogenesis and Evolution Section at the US National Institute of Allergy and Infectious Diseases.
|
EMBO Rep
|
2014
|
0.76
|
98
|
Reply to kilbourne.
|
J Infect Dis
|
2009
|
0.76
|
99
|
Detection of seasonal H3N2 influenza A virus by type-specific TaqMan minor groove binder probe assay.
|
Diagn Microbiol Infect Dis
|
2011
|
0.75
|
100
|
Reply to "'BUt nature started it': examining Taubenberger and Morens' view on influenza a virus and dual-use research of concern".
|
MBio
|
2013
|
0.75
|
101
|
An historical antecedent of modern guidelines for community pandemic influenza mitigation.
|
Public Health Rep
|
2009
|
0.75
|