PubRank

George Chaconas

Author PubWeight™ 32.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells. Nat Immunol 2010 2.03
2 Real-time high resolution 3D imaging of the lyme disease spirochete adhering to and escaping from the vasculature of a living host. PLoS Pathog 2008 1.59
3 The role of VlsE antigenic variation in the Lyme disease spirochete: persistence through a mechanism that differs from other pathogens. Mol Microbiol 2007 1.45
4 ResT, a telomere resolvase encoded by the Lyme disease spirochete. Mol Cell 2002 1.45
5 Molecular mechanisms involved in vascular interactions of the Lyme disease pathogen in a living host. PLoS Pathog 2008 1.34
6 Analysis of an ordered, comprehensive STM mutant library in infectious Borrelia burgdorferi: insights into the genes required for mouse infectivity. PLoS One 2012 1.19
7 Mapping of essential replication functions of the linear plasmid lp17 of B. burgdorferi by targeted deletion walking. Mol Microbiol 2005 1.17
8 Conservation of plasmid maintenance functions between linear and circular plasmids in Borrelia burgdorferi. J Bacteriol 2003 1.08
9 Investigation of the genes involved in antigenic switching at the vlsE locus in Borrelia burgdorferi: an essential role for the RuvAB branch migrase. PLoS Pathog 2009 1.07
10 Mixing active-site components: a recipe for the unique enzymatic activity of a telomere resolvase. Proc Natl Acad Sci U S A 2004 1.05
11 Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules. Mol Microbiol 2012 1.05
12 3D reconstruction of the Mu transposase and the Type 1 transpososome: a structural framework for Mu DNA transposition. Genes Dev 2005 1.04
13 Differential telomere processing by Borrelia telomere resolvases in vitro but not in vivo. J Bacteriol 2006 1.04
14 Catalytic residues of the telomere resolvase ResT: a pattern similar to, but distinct from, tyrosine recombinases and type IB topoisomerases. J Biol Chem 2004 1.04
15 Illuminating the roles of the Borrelia burgdorferi adhesins. Trends Microbiol 2013 1.03
16 Sequence-specific recognition but position-dependent cleavage of two distinct telomeres by the Borrelia burgdorferi telomere resolvase, ResT. Mol Microbiol 2003 1.01
17 Characterization and in vitro reaction properties of 19 unique hairpin telomeres from the linear plasmids of the lyme disease spirochete. J Biol Chem 2009 1.00
18 Fusion of hairpin telomeres by the B. burgdorferi telomere resolvase ResT implications for shaping a genome in flux. Mol Cell 2005 0.97
19 The Mu three-site synapse: a strained assembly platform in which delivery of the L1 transposase binding site triggers catalytic commitment. Mol Cell 2002 0.94
20 Telomere resolution by Borrelia burgdorferi ResT through the collaborative efforts of tethered DNA binding domains. Mol Microbiol 2007 0.92
21 HrpA, a DEAH-box RNA helicase, is involved in global gene regulation in the Lyme disease spirochete. PLoS One 2011 0.90
22 Unexpected twist: harnessing the energy in positive supercoils to control telomere resolution. Mol Microbiol 2006 0.89
23 Uncoupling the chemical steps of telomere resolution by ResT. J Biol Chem 2005 0.88
24 The nucleotide excision repair system of Borrelia burgdorferi is the sole pathway involved in repair of DNA damage by UV light. J Bacteriol 2013 0.84
25 Hairpin Telomere Resolvases. Microbiol Spectr 2014 0.83
26 Topology-dependent transcription in linear and circular plasmids of the segmented genome of Borrelia burgdorferi. Mol Microbiol 2007 0.82
27 Purification and properties of the plasmid maintenance proteins from the Borrelia burgdorferi linear plasmid lp17. J Bacteriol 2008 0.82
28 Effect of mutations in the C-terminal domain of Mu B on DNA binding and interactions with Mu A transposase. J Biol Chem 2003 0.82
29 Identification of the determinant conferring permissive substrate usage in the telomere resolvase, ResT. J Biol Chem 2009 0.82
30 Suggested role for G4 DNA in recombinational switching at the antigenic variation locus of the Lyme disease spirochete. PLoS One 2013 0.81
31 High-throughput screening identifies three inhibitor classes of the telomere resolvase from the lyme disease spirochete. Antimicrob Agents Chemother 2009 0.80