Nanographene oxide-based radioimmunoconstructs for in vivo targeting and SPECT imaging of HER2-positive tumors.

PubWeight™: 0.83‹?›

🔗 View Article (PMID 23171545)

Published in Biomaterials on November 19, 2012

Authors

Bart Cornelissen1, Sarah Able, Veerle Kersemans, Philip A Waghorn, Sverre Myhra, Kerstin Jurkshat, Alison Crossley, Katherine A Vallis

Author Affiliations

1: CR-UK/MRC Gray Institute for Radiation Oncology and Biology, Department of Oncology, University of Oxford, Oxford OX3 7LE, UK.

Articles by these authors

Regional Nodal Irradiation in Early-Stage Breast Cancer. N Engl J Med (2015) 4.94

Antitumor effects and normal tissue toxicity of 111In-labeled epidermal growth factor administered to athymic mice bearing epidermal growth factor receptor-positive human breast cancer xenografts. J Nucl Med (2003) 1.74

Prospective comparison of breast pain in patients participating in a randomized trial of breast-conserving surgery and tamoxifen with or without radiotherapy. Int J Radiat Oncol Biol Phys (2003) 1.67

Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma. J Clin Invest (2012) 1.57

Selective permeabilization of the blood-brain barrier at sites of metastasis. J Natl Cancer Inst (2013) 1.56

A comparison of the behavior of (64)Cu-acetate and (64)Cu-ATSM in vitro and in vivo. J Nucl Med (2013) 1.55

123I-labeled HIV-1 tat peptide radioimmunoconjugates are imported into the nucleus of human breast cancer cells and functionally interact in vitro and in vivo with the cyclin-dependent kinase inhibitor, p21(WAF-1/Cip-1). Eur J Nucl Med Mol Imaging (2006) 1.48

(111)In-labeled trastuzumab (Herceptin) modified with nuclear localization sequences (NLS): an Auger electron-emitting radiotherapeutic agent for HER2/neu-amplified breast cancer. J Nucl Med (2007) 1.25

A population-based case-cohort study of the risk of myocardial infarction following radiation therapy for breast cancer. Radiother Oncol (2007) 1.22

Putative functions and functional efficiency of ordered cuticular nanoarrays on insect wings. Biophys J (2008) 1.16

Carbon nanotubes contain metal impurities which are responsible for the "electrocatalysis" seen at some nanotube-modified electrodes. Angew Chem Int Ed Engl (2006) 1.15

Computational analysis of the number, area and density of gamma-H2AX foci in breast cancer cells exposed to (111)In-DTPA-hEGF or gamma-rays using Image-J software. Int J Radiat Biol (2009) 1.08

The anodic stripping voltammetry of nanoparticles: electrochemical evidence for the surface agglomeration of silver nanoparticles. Nanoscale (2013) 1.07

Targeting the nucleus: an overview of Auger-electron radionuclide therapy. Curr Drug Discov Technol (2010) 1.03

Cone beam computed tomography guidance for setup of patients receiving accelerated partial breast irradiation. Int J Radiat Oncol Biol Phys (2007) 1.02

Silver nanoparticles and silver nitrate induce high toxicity to Pseudokirchneriella subcapitata, Daphnia magna and Danio rerio. Sci Total Environ (2013) 0.97

Fluorescent copper(II) bis(thiosemicarbazonates): synthesis, structures, electron paramagnetic resonance, radiolabeling, in vitro cytotoxicity and confocal fluorescence microscopy studies. Chem Asian J (2010) 0.97

Proteomic analyses reveal high expression of decorin and endoplasmin (HSP90B1) are associated with breast cancer metastasis and decreased survival. PLoS One (2012) 0.96

Oxygenated edge plane sites slow the electron transfer of the ferro-/ferricyanide redox couple at graphite electrodes. Chemphyschem (2006) 0.95

Trastuzumab-resistant breast cancer cells remain sensitive to the auger electron-emitting radiotherapeutic agent 111In-NLS-trastuzumab and are radiosensitized by methotrexate. J Nucl Med (2008) 0.95

Imaging DNA damage in vivo using gammaH2AX-targeted immunoconjugates. Cancer Res (2011) 0.94

An assessment of the fate, behaviour and environmental risk associated with sunscreen TiO₂ nanoparticles in UK field scenarios. Sci Total Environ (2011) 0.94

Antitumor effects and normal-tissue toxicity of 111In-nuclear localization sequence-trastuzumab in athymic mice bearing HER-positive human breast cancer xenografts. J Nucl Med (2010) 0.92

Epidermal growth factor receptor inhibition modulates the nuclear localization and cytotoxicity of the Auger electron emitting radiopharmaceutical 111In-DTPA human epidermal growth factor. J Nucl Med (2007) 0.91

Removal of amorphous carbon for the efficient sidewall functionalisation of single-walled carbon nanotubes. Chem Commun (Camb) (2007) 0.90

A high-throughput induction gene trap approach defines C4ST as a target of BMP signaling. Mech Dev (2002) 0.90

Preclinical pharmacokinetic, biodistribution, toxicology, and dosimetry studies of 111In-DTPA-human epidermal growth factor: an auger electron-emitting radiotherapeutic agent for epidermal growth factor receptor-positive breast cancer. J Nucl Med (2006) 0.89

Relationship between induction of phosphorylated H2AX and survival in breast cancer cells exposed to 111In-DTPA-hEGF. J Nucl Med (2008) 0.88

Contact-induced apical asymmetry drives the thigmotropic responses of Candida albicans hyphae. Cell Microbiol (2014) 0.88

Toenail selenium status and DNA repair capacity among female BRCA1 mutation carriers. Cancer Causes Control (2010) 0.87

Use of high-purity metal-catalyst-free multiwalled carbon nanotubes to avoid potential experimental misinterpretations. Langmuir (2007) 0.87

Clinical imaging of tumor angiogenesis. Future Oncol (2012) 0.87

Electroanalysis using macro-, micro-, and nanochemical architectures on electrode surfaces. Bulk surface modification of glassy carbon microspheres with gold nanoparticles and their electrical wiring using carbon nanotubes. Anal Chem (2006) 0.85

Zinc oxide nanoparticles toxicity to Daphnia magna: size-dependent effects and dissolution. Environ Toxicol Chem (2013) 0.85

ErbB-2 blockade and prenyltransferase inhibition alter epidermal growth factor and epidermal growth factor receptor trafficking and enhance (111)In-DTPA-hEGF Auger electron radiation therapy. J Nucl Med (2011) 0.85

In vitro and in vivo evaluation of [123I]-VEGF165 as a potential tumor marker. Nucl Med Biol (2005) 0.85

Amplification of DNA damage by a γH2AX-targeted radiopharmaceutical. Nucl Med Biol (2012) 0.83

Investigating the thermodynamic causes behind the anomalously large shifts in pKa values of benzoic acid-modified graphite and glassy carbon surfaces. Langmuir (2007) 0.83

Valine-based biphenylsulphonamide matrix metalloproteinase inhibitors as tumor imaging agents. Appl Radiat Isot (2006) 0.83

Endogenous cystinyl aminopeptidase in Chinese hamster ovary cells: characterization by [125I]Ang IV binding and catalytic activity. Biochem Pharmacol (2004) 0.83

Relationship between chromatin structure and sensitivity to molecularly targeted auger electron radiation therapy. Int J Radiat Oncol Biol Phys (2012) 0.82

WS₂ 2D nanosheets in 3D nanoflowers. Chem Commun (Camb) (2014) 0.82

Calibration of AFM cantilever spring constants. Ultramicroscopy (2003) 0.82

Methotrexate, paclitaxel, and doxorubicin radiosensitize HER2-amplified human breast cancer cells to the Auger electron-emitting radiotherapeutic agent (111)In-NLS-trastuzumab. J Nucl Med (2010) 0.81

A dual radiolabelling approach for tracking metal complexes: investigating the speciation of copper bis(thiosemicarbazonates) in vitro and in vivo. Metallomics (2015) 0.81

CCR5 pharmacology methodologies and associated applications. Methods Enzymol (2009) 0.81

Glial activation in the early stages of brain metastasis: TSPO as a diagnostic biomarker. J Nucl Med (2014) 0.81

A kit formulated under good manufacturing practices for labeling human epidermal growth factor with 111In for radiotherapeutic applications. J Nucl Med (2004) 0.81

Synergistic modulation of cystinyl aminopeptidase by divalent cation chelators. Biochem Pharmacol (2004) 0.81

Concurrent cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy and radiotherapy for breast carcinoma: a well tolerated adjuvant regimen. Cancer (2002) 0.80

Pre-clinical evaluation of a 3-nitro-1,2,4-triazole analogue of [18F]FMISO as hypoxia-selective tracer for PET. Nucl Med Biol (2010) 0.80

Peptide and nonpeptide antagonist interaction with constitutively active human AT1 receptors. Biochem Pharmacol (2003) 0.80

Designing Zn(II) and Cu(II) derivatives as probes for in vitro fluorescence imaging. Dalton Trans (2007) 0.80

Oxygen reduction at sparse arrays of platinum nanoparticles in aqueous acid: hydrogen peroxide as a liberated two electron intermediate. Phys Chem Chem Phys (2013) 0.79

The level of insulin growth factor-1 receptor expression is directly correlated with the tumor uptake of (111)In-IGF-1(E3R) in vivo and the clonogenic survival of breast cancer cells exposed in vitro to trastuzumab (Herceptin). Nucl Med Biol (2008) 0.79

Molecular radiotherapy using cleavable radioimmunoconjugates that target EGFR and γH2AX. Mol Cancer Ther (2013) 0.78

Postoperative radiotherapy for breast cancer: growing evidence for an impact on survival. J Natl Cancer Inst (2004) 0.78

111In-BnDTPA-F3: an Auger electron-emitting radiotherapeutic agent that targets nucleolin. EJNMMI Res (2012) 0.78

Cellular confocal fluorescence studies and cytotoxic activity of new Zn(II) bis(thiosemicarbazonato) complexes. Dalton Trans (2008) 0.77

Analysis of human fibroblasts by atomic force microscopy. Methods Mol Biol (2004) 0.77

Building block syntheses of gallic acid monomers and tris-(O-gallyl)-gallic acid dendrimers chemically attached to graphite powder: a comparative study of their uptake of Al(III) ions. Langmuir (2010) 0.77

Metal ion modulation of cystinyl aminopeptidase. Biochem J (2005) 0.77

Preparation and characterization of negatively charged poly(lactic-co-glycolic acid) microspheres. J Pharm Sci (2009) 0.77

Fluorescent gallium and indium bis(thiosemicarbazonates) and their radiolabelled analogues: synthesis, structures and cellular confocal fluorescence imaging investigations. Dalton Trans (2011) 0.77

Synthesis of sulfonamide conjugates of Cu(II), Ga(III), In(III), Re(V) and Zn(II) complexes: carbonic anhydrase inhibition studies and cellular imaging investigations. Dalton Trans (2015) 0.77

Tryptophane-based biphenylsulfonamide matrix metalloproteinase inhibitors as tumor imaging agents. Cancer Biother Radiopharm (2005) 0.77

Multiwalled carbon nanotubes with molybdenum dioxide nanoplugs--new chemical nanoarchitectures by electrochemical modification. Small (2006) 0.77

In vivo monitoring of intranuclear p27(kip1) protein expression in breast cancer cells during trastuzumab (Herceptin) therapy. Nucl Med Biol (2009) 0.77

Analytical approaches to support current understanding of exposure, uptake and distributions of engineered nanoparticles by aquatic and terrestrial organisms. Ecotoxicology (2014) 0.76

Antisense imaging of epidermal growth factor-induced p21(WAF-1/CIP-1) gene expression in MDA-MB-468 human breast cancer xenografts. Eur J Nucl Med Mol Imaging (2003) 0.76

Properties of [(111)In]-labeled HIV-1 tat peptide radioimmunoconjugates in tumor-bearing mice following intravenous or intratumoral injection. Nucl Med Biol (2008) 0.76

A joint experimental and computational search for authentic nano-electrocatalytic effects: electrooxidation of nitrite and L-ascorbate on gold nanoparticle-modified glassy carbon electrodes. Small (2012) 0.76

In vivo apoptosis detection with radioiodinated Annexin V in LoVo tumour-bearing mice following Tipifarnib (Zarnestra, R115777) farnesyltransferase inhibitor therapy. Nucl Med Biol (2005) 0.76

Synthesis and characterization of carbon nanotubes covalently functionalized with amphiphilic polymer coated superparamagnetic nanocrystals. J Colloid Interface Sci (2012) 0.76

Comparative antiproliferative effects of (111)In-DTPA-hEGF, chemotherapeutic agents and gamma-radiation on EGFR-positive breast cancer cells. Nucl Med Biol (2002) 0.75

PET imaging of DNA damage using (89)Zr-labelled anti-γH2AX-TAT immunoconjugates. Eur J Nucl Med Mol Imaging (2015) 0.75

Synthesis, biodistribution and effects of farnesyltransferase inhibitor therapy on tumour uptake in mice of 99mTc labelled epidermal growth factor. Nucl Med Commun (2005) 0.75

Super-washing does not leave single walled carbon nanotubes iron-free. Analyst (2006) 0.75

Electrochemically polymerised composites of multi-walled carbon nanotubes and poly(vinylferrocene) and their use as modified electrodes: application to glucose sensing. Analyst (2006) 0.75

PET and SPECT Imaging for the Acceleration of Anti-Cancer Drug Development. Curr Drug Targets (2015) 0.75

Uptake, internalization and nuclear translocation of radioimmunotherapeutic agents. Ther Deliv (2014) 0.75

Measuring anisotropic friction on WTe2 using atomic force microscopy in the force-distance and friction modes. J Nanosci Nanotechnol (2010) 0.75

Influence of farnesyl transferase inhibitor treatment on epidermal growth factor receptor status. Nucl Med Biol (2004) 0.75

Interaction between co-deposited metals during stripping voltammetry at boron-doped diamond electrodes. Phys Chem Chem Phys (2005) 0.75

A DCE-MRI imaging-based model for simulation of vascular tumour growth. Conf Proc IEEE Eng Med Biol Soc (2016) 0.75

Chemically amplified photoresist for high resolution autoradiography in targeted radiotherapy. Biomaterials (2011) 0.75

111In-labeled immunoconjugates (ICs) bispecific for the epidermal growth factor receptor (EGFR) and cyclin-dependent kinase inhibitor, p27Kip1. Cancer Biother Radiopharm (2009) 0.75

Contrasting pKa of protonated bis(3-aminopropyl)-terminated polyethylene glycol "Jeffamine" and the associated thermodynamic parameters in solution and covalently attached to graphite surfaces. Chemistry (2007) 0.75

Absorbed dose evaluation of auger electron-emitting radionuclides: impact of input decay spectra on dose point kernels and S-values. Phys Med Biol (2017) 0.75

Photoresists as a high spatial resolution autoradiography substrate for quantitative mapping of intra- and sub-cellular distribution of Auger electron emitting radionuclides. Int J Radiat Biol (2012) 0.75

Corrigendum: A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition. Sci Rep (2016) 0.75

Targeted molecular radiotherapy. Curr Drug Discov Technol (2010) 0.75

Characterization of single α-tracks by photoresist detection and AFM analysis-focus on biomedical science and technology. Phys Med Biol (2013) 0.75