Published in Aust Vet J on September 24, 2012
A retrospective study of Babesia macropus associated with morbidity and mortality in eastern grey kangaroos (Macropus giganteus) and agile wallabies (Macropus agilis). Int J Parasitol Parasites Wildl (2015) 0.76
Full genome characterization of the culicoides-borne marsupial orbiviruses: Wallal virus, Mudjinbarry virus and Warrego viruses. PLoS One (2014) 0.75
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science (1995) 17.76
JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell (1994) 16.30
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem (1995) 9.56
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science (2000) 8.56
Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. Science (1995) 7.87
Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science (1995) 7.37
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol Cell Biol (1996) 6.91
cPLA2 is phosphorylated and activated by MAP kinase. Cell (1993) 6.61
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med (2000) 6.32
Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development. Curr Opin Cell Biol (1998) 6.28
Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. Science (1994) 6.07
Selective interaction of JNK protein kinase isoforms with transcription factors. EMBO J (1996) 6.07
Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways. J Mol Med (Berl) (1996) 5.77
Integration of MAP kinase signal transduction pathways at the serum response element. Science (1995) 5.45
Posterior cortical atrophy. Arch Neurol (1988) 5.39
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature (1997) 5.29
Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3. Science (2000) 5.20
Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma. Nat Genet (1993) 5.00
A mammalian scaffold complex that selectively mediates MAP kinase activation. Science (1998) 4.78
A cytoplasmic inhibitor of the JNK signal transduction pathway. Science (1997) 4.56
Pathogenesis and genetics of pre-eclampsia. Lancet (2001) 4.54
The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development. Neuron (1999) 4.51
Defective T cell differentiation in the absence of Jnk1. Science (1998) 4.40
Evaluation of new anti-infective drugs for the treatment of urinary tract infection. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis (1992) 4.20
Regulation of JNK signaling by GSTp. EMBO J (1999) 4.06
Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2. Immunity (1998) 3.70
Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation. J Biol Chem (1995) 3.69
An osmosensing signal transduction pathway in mammalian cells. Science (1994) 3.49
The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. J Biol Chem (1996) 3.38
Identification of substrate recognition determinants for human ERK1 and ERK2 protein kinases. J Biol Chem (1991) 3.37
A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila. Genes Dev (1996) 3.21
Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6. J Biol Chem (1998) 3.21
The JIP group of mitogen-activated protein kinase scaffold proteins. Mol Cell Biol (1999) 3.18
Involvement of mitogen-activated protein kinase pathways in the nuclear responses and cytokine production induced by Salmonella typhimurium in cultured intestinal epithelial cells. J Immunol (1997) 3.07
Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation. EMBO J (1999) 2.96
Signal transduction within the nucleus by mitogen-activated protein kinase. J Biol Chem (1992) 2.93
Emerging viral diseases of Southeast Asia and the Western Pacific. Emerg Infect Dis (2001) 2.91
Signal transduction by tumor necrosis factor mediated by JNK protein kinases. Mol Cell Biol (1994) 2.90
Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals. Trends Biochem Sci (1998) 2.83
Serum-induced translocation of mitogen-activated protein kinase to the cell surface ruffling membrane and the nucleus. J Cell Biol (1993) 2.74
Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice. EMBO J (1999) 2.70
WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans. Cell (1999) 2.69
Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors. Mol Cell Biol (1997) 2.58
A conserved p38 mitogen-activated protein kinase pathway regulates Drosophila immunity gene expression. Mol Cell Biol (1998) 2.57
Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1. EMBO J (1998) 2.54
MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines. Genes Dev (2001) 2.48
Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase. Proc Natl Acad Sci U S A (1997) 2.46
The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif. Mol Cell Biol (1998) 2.44
Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway. EMBO J (1998) 2.41
Tumor-promoting phorbol diesters cause the phosphorylation of epidermal growth factor receptors in normal human fibroblasts at threonine-654. Proc Natl Acad Sci U S A (1985) 2.36
JNK is required for effector T-cell function but not for T-cell activation. Nature (2000) 2.33
The exceptionally large genome of Hendra virus: support for creation of a new genus within the family Paramyxoviridae. J Virol (2000) 2.26
Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway. Science (1997) 2.25
Control of MAP kinase activation by the mitogen-induced threonine/tyrosine phosphatase PAC1. Nature (1994) 2.24
Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity. Proc Natl Acad Sci U S A (1997) 2.21
Encephalitis caused by a Lyssavirus in fruit bats in Australia. Emerg Infect Dis (1997) 2.18
Treatment of acromegaly with the growth hormone-receptor antagonist pegvisomant. N Engl J Med (2000) 2.16
The native structure of the activated Raf protein kinase is a membrane-bound multi-subunit complex. J Biol Chem (1994) 2.16
A phosphorylation site located in the NH2-terminal domain of c-Myc increases transactivation of gene expression. J Biol Chem (1991) 2.13
Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation. Genes Dev (1999) 2.08
Long-term treatment of acromegaly with pegvisomant, a growth hormone receptor antagonist. Lancet (2001) 2.08
Massive haemoptysis. BMJ (1990) 2.07
Isolation and characterization of two growth factor-stimulated protein kinases that phosphorylate the epidermal growth factor receptor at threonine 669. J Biol Chem (1991) 2.06
Mitogen-activated protein kinase stimulation by a tyrosine kinase-negative epidermal growth factor receptor. J Biol Chem (1993) 2.06
An apparently new virus (family Paramyxoviridae) infectious for pigs, humans, and fruit bats. Emerg Infect Dis (1998) 2.03
Phosphorylation-dependent targeting of c-Jun ubiquitination by Jun N-kinase. Oncogene (1996) 2.00
Molecular determinants that mediate selective activation of p38 MAP kinase isoforms. EMBO J (2000) 2.00
Spinal muscular atrophy disrupts the interaction of ZPR1 with the SMN protein. Nat Cell Biol (2001) 2.00
Tumor necrosis factor alpha-induced E-selectin expression is activated by the nuclear factor-kappaB and c-JUN N-terminal kinase/p38 mitogen-activated protein kinase pathways. J Biol Chem (1997) 1.99
The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases. Mol Cell Biol (1999) 1.99
Requirement of the JIP1 scaffold protein for stress-induced JNK activation. Genes Dev (2001) 1.96
Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand. J Neurosci (2001) 1.93
Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3. Mol Cell Biol (2000) 1.93
The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes. J Exp Med (1998) 1.91
Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases. Mol Cell Biol (1997) 1.88
Modulation of HIV-1 infectivity by MAPK, a virion-associated kinase. EMBO J (1998) 1.86
Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression. Proc Natl Acad Sci U S A (1999) 1.83
Role of mitogen-activated protein kinase kinase 4 in cancer. Oncogene (2007) 1.79
Phosphoglycerate kinase polymorphism in kangaroos provides further evidence for paternal X inactivation. Nat New Biol (1971) 1.78
GADD45gamma mediates the activation of the p38 and JNK MAP kinase pathways and cytokine production in effector TH1 cells. Immunity (2001) 1.73
Directed genetic change model for X chromosome inactivation in eutherian mammals. Nature (1971) 1.73
Regulation of transcription factor function by phosphorylation. Cell Mol Life Sci (2000) 1.71
Absence of close linkage between maternal genes for susceptibility to pre-eclampsia/eclampsia and HLA DR beta. Lancet (1990) 1.67
Transactivation of gene expression by Myc is inhibited by mutation at the phosphorylation sites Thr-58 and Ser-62. Proc Natl Acad Sci U S A (1993) 1.65
Independent regulation of JNK/p38 mitogen-activated protein kinases by metabolic oxidative stress in the liver. Proc Natl Acad Sci U S A (1996) 1.63
Regulation of MAP kinases by docking domains. Biol Cell (2001) 1.60
Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade. Proc Natl Acad Sci U S A (1996) 1.57
Requirement for transcription factor NFAT in interleukin-2 expression. Mol Cell Biol (1999) 1.56
MOM-4, a MAP kinase kinase kinase-related protein, activates WRM-1/LIT-1 kinase to transduce anterior/posterior polarity signals in C. elegans. Mol Cell (1999) 1.56
Insulin stimulates cellular iron uptake and causes the redistribution of intracellular transferrin receptors to the plasma membrane. J Biol Chem (1986) 1.56
Up-regulation of MET but not neural cell adhesion molecule expression by the PAX3-FKHR fusion protein in alveolar rhabdomyosarcoma. Cancer Res (1998) 1.55
Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor. Science (1996) 1.55
Genetics of hypertension in pregnancy: possible single gene control of pre-eclampsia and eclampsia in the descendants of eclamptic women. Br J Obstet Gynaecol (1986) 1.53
Reprogramming the signalling requirement for AP-1 (activator protein-1) activation during differentiation of precursor CD4+ T-cells into effector Th1 and Th2 cells. Genes Funct (1997) 1.52
Tumor-promoting phorbol diesters mediate phosphorylation of the epidermal growth factor receptor. J Biol Chem (1984) 1.52
c-Jun is a JNK-independent coactivator of the PU.1 transcription factor. J Biol Chem (1999) 1.49
Mitogen-activated protein kinase-mediated Fas apoptotic signaling pathway. Proc Natl Acad Sci U S A (1997) 1.47