Tomohisa Takagi

Author PubWeight™ 99.16‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Enhanced intestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha deficient mice. J Gastroenterol Hepatol 2003 1.58
2 A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise. Gut 2012 1.57
3 Relationship between circulating cytokine levels and physical or psychological functioning in patients with advanced cancer. Clin Biochem 2011 1.56
4 Impact of Helicobacter pylori eradication on circulating adiponectin in humans. Helicobacter 2012 1.50
5 Role of nociceptors/neuropeptides in the pathogenesis of visceral hypersensitivity of nonerosive reflux disease. Dig Dis Sci 2012 1.49
6 Role of pancreatic trypsin in chronic esophagitis induced by gastroduodenal reflux in rats. J Gastroenterol 2006 1.47
7 Hemin ameliorates indomethacin-induced small intestinal injury in mice through the induction of heme oxygenase-1. J Gastroenterol Hepatol 2013 1.45
8 A Mouse Model of Metabolic Syndrome; Increase in Visceral Adipose Tissue Precedes the Development of Fatty Liver and Insulin Resistance in High-Fat Diet-Fed Male KK/Ta Mice. J Clin Biochem Nutr 2008 1.24
9 Lansoprazole, a proton pump inhibitor, reduces the severity of indomethacin-induced rat enteritis. Int J Mol Med 2006 1.24
10 Lansoprazole ameliorates intestinal mucosal damage induced by ischemia-reperfusion in rats. World J Gastroenterol 2004 1.17
11 Molecular fingerprints of neutrophil-dependent oxidative stress in inflammatory bowel disease. J Gastroenterol 2007 1.13
12 Cytokine-induced neutrophil accumulation in the pathogenesis of acute reflux esophagitis in rats. Int J Mol Med 2005 1.13
13 Reduced intestinal inflammation induced by dextran sodium sulfate in interleukin-6-deficient mice. Int J Mol Med 2004 1.13
14 Ability of a novel blue laser imaging system for the diagnosis of colorectal polyps. Dig Endosc 2013 1.11
15 Silver nanoparticles as a safe preservative for use in cosmetics. Nanomedicine 2010 1.08
16 Suppression of intestinal ischemia-reperfusion injury by a specific peroxisome proliferator-activated receptor-gamma ligand, pioglitazone, in rats. Redox Rep 2002 1.05
17 Whole body hyperthermia improves obesity-induced insulin resistance in diabetic mice. Int J Hyperthermia 2007 1.03
18 Tumor necrosis factor-alpha-induced cytokine-induced neutrophil chemoattractant-1 (CINC-1) production by rat gastric epithelial cells: role of reactive oxygen species and nuclear factor-kappaB. J Pharmacol Exp Ther 2004 1.02
19 Astaxanthin protects mesangial cells from hyperglycemia-induced oxidative signaling. J Cell Biochem 2008 1.00
20 The radical scavenger edaravone enhances the anti-tumor effects of CPT-11 in murine colon cancer by increasing apoptosis via inhibition of NF-kappaB. Cancer Lett 2005 1.00
21 Methylparaben potentiates UV-induced damage of skin keratinocytes. Toxicology 2006 0.99
22 Efficacy of magnifying endoscopy with flexible spectral imaging color enhancement in the diagnosis of colorectal tumors. J Gastroenterol 2011 0.97
23 Reactive oxygen species-quenching and anti-apoptotic effect of polaprezinc on indomethacin-induced small intestinal epithelial cell injury. J Gastroenterol 2010 0.97
24 Heme oxygenase-1: a novel therapeutic target for gastrointestinal diseases. J Clin Biochem Nutr 2011 0.96
25 A novel potent inhibitor of inducible nitric oxide inhibitor, ONO-1714, reduces intestinal ischemia-reperfusion injury in rats. Nitric Oxide 2004 0.94
26 Bofutsushosan, an Oriental Herbal Medicine, Attenuates the Weight Gain of White Adipose Tissue and the Increased Size of Adipocytes Associated with the Increase in Their Expression of Uncoupling Protein 1 in High-Fat Diet-Fed Male KK/Ta mice. J Clin Biochem Nutr 2008 0.94
27 Efficacy of hyaluronic acid in endoscopic mucosal resection of colorectal tumors. J Gastroenterol Hepatol 2011 0.94
28 Effect of hyperthermia combined with gemcitabine on apoptotic cell death in cultured human pancreatic cancer cell lines. Int J Hyperthermia 2009 0.94
29 Effect of a novel water-soluble vitamin E derivative as a cure for TNBS-induced colitis in rats. Int J Mol Med 2006 0.94
30 Phase II trial of combined regional hyperthermia and gemcitabine for locally advanced or metastatic pancreatic cancer. Int J Hyperthermia 2012 0.94
31 Prevention of Indomethacin-Induced Gastric Mucosal Injury in Helicobacter pylori-Negative Healthy Volunteers: A Comparison Study Rebamipide vs Famotidine. J Clin Biochem Nutr 2008 0.93
32 Neutrophil-dependent oxidative stress in ulcerative colitis. J Clin Biochem Nutr 2007 0.93
33 Prophylactic effect of rebamipide on aspirin-induced gastric lesions and disruption of tight junctional protein zonula occludens-1 distribution. J Pharmacol Sci 2008 0.90
34 Inhibitory effect of polaprezinc on the inflammatory response to Helicobacter pylori. Can J Gastroenterol 2002 0.90
35 Involvement of reactive oxygen species in indomethacin-induced apoptosis of small intestinal epithelial cells. J Gastroenterol 2009 0.89
36 Antitumor effect of pretreatment for colon cancer cells with hyperthermia plus geranylgeranylacetone in experimental metastasis models and a subcutaneous tumor model of colon cancer in mice. Int J Hyperthermia 2009 0.89
37 Transcriptome Analysis for Cytoprotective Actions of Rebamipide against Indomethacin-Induced Gastric Mucosal Injury in Rats. J Clin Biochem Nutr 2007 0.89
38 Anti-tryptase treatment using nafamostat mesilate has a therapeutic effect on experimental colitis. Scand J Gastroenterol 2006 0.88
39 A specific peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligand, pioglitazone, ameliorates gastric mucosal damage induced by ischemia and reperfusion in rats. Redox Rep 2002 0.87
40 The detection of surface patterns by flexible spectral imaging color enhancement without magnification for diagnosis of colorectal polyps. Int J Colorectal Dis 2011 0.87
41 Rosuvastatin, a new HMG-CoA reductase inhibitor, reduces the colonic inflammatory response in dextran sulfate sodium-induced colitis in mice. Int J Mol Med 2006 0.87
42 Regular exercise reduces colon tumorigenesis associated with suppression of iNOS. Biochem Biophys Res Commun 2010 0.87
43 Endogenous hydrogen sulfide is an anti-inflammatory molecule in dextran sodium sulfate-induced colitis in mice. Dig Dis Sci 2010 0.87
44 Protective effects of preischemic treatment with pioglitazone, a peroxisome proliferator-activated receptor-gamma ligand, on lung ischemia-reperfusion injury in rats. Eur J Cardiothorac Surg 2004 0.86
45 Role of the thrombin/protease-activated receptor 1 pathway in intestinal ischemia-reperfusion injury in rats. Am J Physiol Gastrointest Liver Physiol 2006 0.85
46 Heat-shock protein 70-overexpressing gastric epithelial cells are resistant to indomethacin-induced apoptosis. Digestion 2009 0.85
47 Toxic megacolon associated with cytomegalovirus infection in a patient with steroid-naïve ulcerative colitis. Intern Med 2012 0.85
48 Expression of inducible nitric oxide synthase and nitric oxide-modified proteins in Helicobacter pylori-associated atrophic gastric mucosa. J Gastroenterol Hepatol 2008 0.84
49 Possibility of ex vivo animal training model for colorectal endoscopic submucosal dissection. Int J Colorectal Dis 2012 0.84
50 Synergistic effect of HLA class II loci and cytokine gene polymorphisms on the risk of gastric cancer in Japanese patients with Helicobacter pylori infection. Int J Cancer 2009 0.84
51 Rotenone, a mitochondrial electron transport inhibitor, ameliorates ischemia-reperfusion-induced intestinal mucosal damage in rats. Redox Rep 2004 0.84
52 Edaravone, a newly developed radical scavenger, protects against ischemia-reperfusion injury of the small intestine in rats. Int J Mol Med 2004 0.84
53 Gene expression profiles on hypoxia and reoxygenation in rat gastric epithelial cells: a high-density DNA microarray analysis. Digestion 2006 0.84
54 Role of tumor necrosis factor-α in the pathogenesis of indomethacin-induced small intestinal injury in mice. Int J Mol Med 2011 0.84
55 Prevention of colonic spasm using L-menthol in colonoscopic examination. Int J Colorectal Dis 2014 0.83
56 Heat-shock protein 27 (Hsp27) as a target of methylglyoxal in gastrointestinal cancer. Biochim Biophys Acta 2011 0.83
57 Role of metallothionein in murine experimental colitis. Int J Mol Med 2013 0.83
58 Multifaceted Assessment of Chronic Gastritis: A Study of Correlations between Serological, Endoscopic, and Histological Diagnostics. Gastroenterol Res Pract 2011 0.83
59 Acetyl salicylic acid induces damage to intestinal epithelial cells by oxidation-related modifications of ZO-1. Am J Physiol Gastrointest Liver Physiol 2012 0.83
60 Partially hydrolyzed guar gum down-regulates colonic inflammatory response in dextran sulfate sodium-induced colitis in mice. J Nutr Biochem 2005 0.83
61 Oligosaccharides from agar inhibit murine intestinal inflammation through the induction of heme oxygenase-1 expression. J Gastroenterol 2012 0.83
62 Management of recurrence of symptoms of gastroesophageal reflux disease: synergistic effect of rebamipide with 15 mg lansoprazole. Dig Dis Sci 2010 0.83
63 Different effects of constitutive nitric oxide synthase and heme oxygenase on pulmonary or liver metastasis of colon cancer in mice. Clin Exp Metastasis 2003 0.83
64 Endoscopic mucosal resection with 0.13% hyaluronic acid solution for colorectal polyps less than 20 mm: a randomized controlled trial. J Gastroenterol Hepatol 2012 0.83
65 Pro-oxidant action of pyrroloquinoline quinone: characterization of protein oxidative modifications. Biosci Biotechnol Biochem 2010 0.82
66 CV-11974, angiotensin II type I receptor antagonist, reduces the severity of indomethacin-induced rat enteritis. Dig Dis Sci 2007 0.82
67 Alpha-tocopherol prevents apoptosis of vascular endothelial cells via a mechanism exceeding that of mere antioxidation. Eur J Pharmacol 2002 0.82
68 Carbon monoxide enhance colonic epithelial restitution via FGF15 derived from colonic myofibroblasts. Biochem Biophys Res Commun 2009 0.82
69 BTB and CNC homolog 1 (Bach1) deficiency ameliorates TNBS colitis in mice: role of M2 macrophages and heme oxygenase-1. Inflamm Bowel Dis 2013 0.82
70 Serpin B1 protects colonic epithelial cell via blockage of neutrophil elastase activity and its expression is enhanced in patients with ulcerative colitis. Am J Physiol Gastrointest Liver Physiol 2012 0.81
71 A novel vitamin E derivative (TMG) protects against gastric mucosal damage induced by ischemia and reperfusion in rats. Dig Dis Sci 2003 0.81
72 Oxidative stress-induced posttranslational modification of TRPV1 expressed in esophageal epithelial cells. Am J Physiol Gastrointest Liver Physiol 2011 0.81
73 An AT1-receptor antagonist and an angiotensin-converting enzyme inhibitor protect against hypoxia-induced apoptosis in human aortic endothelial cells through upregulation of endothelial cell nitric oxide synthase activity. Shock 2003 0.81
74 Blocking of NF-kappaB activation enhances the tumor necrosis factor alpha-induced apoptosis of a human gastric cancer cell line. Cancer Lett 2003 0.81
75 Prediction and treatment of difficult cases in colorectal endoscopic submucosal dissection. Gastroenterol Res Pract 2013 0.80
76 Adoptive cellular therapy enhances the helper T cell response and reduces the number of regulatory T cells. Exp Ther Med 2011 0.80
77 Hyperthermia enhances tumor necrosis factor alpha-induced apoptosis of a human gastric cancer cell line. Cancer Lett 2003 0.80
78 Rebamipide, a gastro-protective drug, inhibits indomethacin-induced apoptosis in cultured rat gastric mucosal cells: association with the inhibition of growth arrest and DNA damage-induced 45 alpha expression. Dig Dis Sci 2005 0.80
79 Suppression of indomethacin-induced apoptosis in the small intestine due to Bach1 deficiency. Free Radic Res 2011 0.80
80 Anoxia/reoxygenation induces epithelial-mesenchymal transition in human colon cancer cell lines. Oncol Rep 2013 0.80
81 Microarray profiling of gene expression patterns in glomerular cells of astaxanthin-treated diabetic mice: a nutrigenomic approach. Int J Mol Med 2006 0.80
82 Whole blood interferon-γ levels predict the therapeutic effects of adoptive T-cell therapy in patients with advanced pancreatic cancer. Int J Cancer 2013 0.80
83 Hyperthermia attenuates TNF-alpha-induced up regulation of endothelial cell adhesion molecules in human arterial endothelial cells. Int J Hyperthermia 2007 0.79
84 Inhibitory effects of catechins on neutrophil-dependent gastric inflammation. Redox Rep 2002 0.79
85 Detection of N-(hexanoyl)lysine in the tropomyosin 1 protein in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat gastric cancer cells. J Clin Biochem Nutr 2011 0.79
86 Rebamipide ameliorates indomethacin-induced small intestinal injury in rats via the inhibition of matrix metalloproteinases activity. J Gastroenterol Hepatol 2012 0.79
87 Reduced small-intestinal injury induced by indomethacin in interleukin-17A-deficient mice. J Gastroenterol Hepatol 2011 0.79
88 Interleukin-10 plasmid DNA inhibits subcutaneous tumor growth of Colon 26 adenocarcinoma in mice. Cancer Lett 2005 0.79
89 Ingestion of low dose pyroglutamyl leucine improves dextran sulfate sodium-induced colitis and intestinal microbiota in mice. J Agric Food Chem 2013 0.78
90 Rosuvastatin reduces rat intestinal ischemia-reperfusion injury associated with the preservation of endothelial nitric oxide synthase protein. World J Gastroenterol 2006 0.78
91 Partially hydrolyzed guar gum affects the expression of genes involved in host defense functions and cholesterol absorption in colonic mucosa of db/db male mice. J Clin Biochem Nutr 2011 0.78
92 MDR1 is related to intestinal epithelial injury induced by acetylsalicylic acid. Cell Physiol Biochem 2013 0.78
93 Antitumor effect of whole body hyperthermia with alpha-galactosylceramide in a subcutaneous tumor model of colon cancer. Int J Hyperthermia 2007 0.78
94 Identification of inflammation-related proteins in a murine colitis model by 2D fluorescence difference gel electrophoresis and mass spectrometry. J Gastroenterol Hepatol 2010 0.78
95 Decrease of the regulatory T-cell population by adoptive T-cell transfer in a mouse colorectal cancer transplant model. Oncol Res 2011 0.77
96 Daikenchuto, a Kampo medicine, regulates intestinal fibrosis associated with decreasing expression of heat shock protein 47 and collagen content in a rat colitis model. Biol Pharm Bull 2011 0.77
97 Plasma ghrelin isoforms and gastric ghrelin O-acyltransferase expression are influenced by Helicobacter pylori status. Nutrition 2012 0.77
98 Gene expression analysis following hypoxia-reoxygenation in rat gastric epithelial cells using a high-density oligonucleotide array. Redox Rep 2004 0.77
99 FGF19 protects colonic epithelial cells against hydrogen peroxide. Digestion 2011 0.77
100 Inflammatory response of esophageal epithelium in combined-type esophagitis in rats: a transcriptome analysis. Int J Mol Med 2006 0.77
101 Proinflammatory role of protease-activated receptor-2 in intestinal ischemia/reperfusion injury in rats. Mol Med Rep 2010 0.77
102 Effects of anticancer agents on cell viability, proliferative activity and cytokine production of peripheral blood mononuclear cells. J Clin Biochem Nutr 2012 0.76
103 Inhibitory effects of red wine extracts on endothelial-dependent adhesive interactions with monocytes induced by oxysterols. Biol Res 2004 0.76
104 alpha-Phenyl-N-tert-butylnitrone provides protection from dextran sulfate sodium-induced colitis in mice. Antioxid Redox Signal 2002 0.76
105 Gastrointestinal Cytoprotection by PPARγ Ligands. PPAR Res 2010 0.76
106 Mast cells are involved in the pathogenesis of indomethacin-induced rat enteritis. J Gastroenterol 2009 0.76
107 Therapeutic roles of carbon monoxide in intestinal ischemia-reperfusion injury. J Gastroenterol Hepatol 2015 0.76
108 Rapamycin Improves Mortality Following Intestinal Ischemia-Reperfusion via the Inhibition of Remote Lung Inflammation in Mice. Digestion 2015 0.75
109 Heat shock protein 70-dependent protective effect of polaprezinc on acetylsalicylic acid-induced apoptosis of rat intestinal epithelial cells. J Clin Biochem Nutr 2011 0.75
110 Successful endoscopic injection sclerotherapy of high-risk gastroesophageal varices in a cirrhotic patient with hemophilia A. Gastroenterol Res Pract 2010 0.75
111 Gene expression profiles of diabetic mice treated with whole body hyperthermia: A high-density DNA microarray analysis. Int J Hyperthermia 2010 0.75
112 Analysis of cardiopulmonary stress during endoscopy: is unsedated transnasal esophagogastroduodenoscopy appropriate for elderly patients? Can J Gastroenterol Hepatol 2013 0.75
113 A case of inoperable duodenal cancer achieving long-term survival after multidisciplinary treatment. Case Rep Gastroenterol 2012 0.75
114 Gastric peroxisome proliferator activator receptor-γ expression and cytoprotective actions of its ligands against ischemia-reperfusion injury in rats. J Clin Biochem Nutr 2011 0.75
115 [Pharmacology of preventive and therapeutic drugs for NSAIDs ulcers in the gastrointestinal tract]. Nihon Rinsho 2011 0.75
116 [Zinc and gastrointestinal disorders]. Nihon Rinsho 2016 0.75
117 [Roles of inflammatory mediators and cytokines in the pathogenesis of inflammatory bowel disease]. Nihon Rinsho 2012 0.75
118 Changes in Intestinal Motility and Gut Microbiota Composition in a Rat Stress Model. Digestion 2017 0.75
119 Early-Stage Gastric Cancer Can Be Found in Improved Atrophic Mucosa over Time from Successful Helicobacter pylori Eradication. Digestion 2017 0.75
120 Preventive effect of agaro-oligosaccharides on non-steroidal anti-inflammatory drug-induced small intestinal injury in mice. J Gastroenterol Hepatol 2014 0.75
121 Anti-inflammatory effects of carbon monoxide-releasing molecule on trinitrobenzene sulfonic acid-induced colitis in mice. Dig Dis Sci 2014 0.75
122 Propionate Promotes Fatty Acid Oxidation through the Up-Regulation of Peroxisome Proliferator-Activated Receptor α in Intestinal Epithelial Cells. J Nutr Sci Vitaminol (Tokyo) 2015 0.75
123 Lipid hydroperoxide-derived modification of proteins in gastrointestinal tract. Subcell Biochem 2014 0.75
124 [Outcome and Problems of Nab-Paclitaxel Therapy for Gastric Cancer in Clinical Practice]. Gan To Kagaku Ryoho 2016 0.75