Published in Stem Cells Transl Med on September 05, 2012
Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation. Sci Rep (2015) 0.89
Combined effect of nerve growth factor and brain‑derived neurotrophic factor on neuronal differentiation of neural stem cells and the potential molecular mechanisms. Mol Med Rep (2014) 0.88
Mood and memory deficits in a model of Gulf War illness are linked with reduced neurogenesis, partial neuron loss, and mild inflammation in the hippocampus. Neuropsychopharmacology (2013) 0.88
Toll-like receptor-2 deficiency induces schizophrenia-like behaviors in mice. Sci Rep (2015) 0.85
Hippocampal injury-induced cognitive and mood dysfunction, altered neurogenesis, and epilepsy: can early neural stem cell grafting intervention provide protection? Epilepsy Behav (2014) 0.84
Grafted Subventricular Zone Neural Stem Cells Display Robust Engraftment and Similar Differentiation Properties and Form New Neurogenic Niches in the Young and Aged Hippocampus. Stem Cells Transl Med (2016) 0.78
The neuroprotective effect exerted by oligodendroglial progenitors on ischemically impaired hippocampal cells. Mol Neurobiol (2013) 0.78
Postnatal age governs the extent of differentiation of hippocampal CA1 and CA3 subfield neural stem/progenitor cells into neurons and oligodendrocytes. Int J Dev Neurosci (2013) 0.78
Pre- and postmortem imaging of transplanted cells. Int J Nanomedicine (2015) 0.76
Interneuron Progenitor Transplantation to Treat CNS Dysfunction. Front Neural Circuits (2016) 0.75
Neural Stem Cell or Human Induced Pluripotent Stem Cell-Derived GABA-ergic Progenitor Cell Grafting in an Animal Model of Chronic Temporal Lobe Epilepsy. Curr Protoc Stem Cell Biol (2016) 0.75
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science (2003) 16.14
Depression: a new animal model sensitive to antidepressant treatments. Nature (1977) 8.76
New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nat Rev Neurosci (2010) 8.09
Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain. Nat Neurosci (2008) 6.13
Adult hippocampal neurogenesis buffers stress responses and depressive behaviour. Nature (2011) 6.08
Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration. Nature (2004) 5.85
Recognition memory and the medial temporal lobe: a new perspective. Nat Rev Neurosci (2007) 5.74
Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation. Nature (2011) 5.17
Adult hippocampal neurogenesis in depression. Nat Neurosci (2007) 4.79
Neurogenesis may relate to some but not all types of hippocampal-dependent learning. Hippocampus (2002) 3.91
Spatial memory, recognition memory, and the hippocampus. Proc Natl Acad Sci U S A (2004) 3.82
Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. J Neurochem (2002) 3.27
Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats. Learn Mem (2009) 3.23
Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor. J Neurosci (1996) 3.04
Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proc Natl Acad Sci U S A (2009) 2.96
Efficacy of doublecortin as a marker to analyse the absolute number and dendritic growth of newly generated neurons in the adult dentate gyrus. Eur J Neurosci (2004) 2.86
Resolving new memories: a critical look at the dentate gyrus, adult neurogenesis, and pattern separation. Neuron (2011) 2.84
Is there a link between adult neurogenesis and learning? Hippocampus (2006) 2.79
GABA sets the tempo for activity-dependent adult neurogenesis. Trends Neurosci (2006) 2.23
Hippocampal damage associated with prolonged and fatal stress in primates. J Neurosci (1989) 2.07
Object recognition memory and the rodent hippocampus. Learn Mem (2009) 2.04
Role of neurotrophic factors in the etiology and treatment of mood disorders. Neuromolecular Med (2004) 1.94
Peripheral BDNF produces antidepressant-like effects in cellular and behavioral models. Neuropsychopharmacology (2010) 1.81
The GABAergic deficit hypothesis of major depressive disorder. Mol Psychiatry (2010) 1.80
Learning deficits in forebrain-restricted brain-derived neurotrophic factor mutant mice. Neuroscience (2003) 1.80
Epigenetic modulation of seizure-induced neurogenesis and cognitive decline. J Neurosci (2007) 1.77
Newly born cells in the ageing dentate gyrus display normal migration, survival and neuronal fate choice but endure retarded early maturation. Eur J Neurosci (2005) 1.74
Neurogenesis and affective disorders. Eur J Neurosci (2011) 1.64
A new role for FGF2 as an endogenous inhibitor of anxiety. J Neurosci (2009) 1.45
Reelin deficiency and displacement of mature neurons, but not neurogenesis, underlie the formation of granule cell dispersion in the epileptic hippocampus. J Neurosci (2006) 1.45
Treatment strategies targeting excess hippocampal activity benefit aged rats with cognitive impairment. Neuropsychopharmacology (2009) 1.39
Stress and depression: possible links to neuron death in the hippocampus. Bipolar Disord (2002) 1.38
Neural stem and progenitor cells retain their potential for proliferation and differentiation into functional neurons despite lower number in aged brain. J Neurosci (2009) 1.37
The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death. Nat Neurosci (2009) 1.33
Chronic temporal lobe epilepsy is associated with severely declined dentate neurogenesis in the adult hippocampus. Neurobiol Dis (2004) 1.33
Medial ganglionic eminence-derived neural stem cell grafts ease spontaneous seizures and restore GDNF expression in a rat model of chronic temporal lobe epilepsy. Stem Cells (2010) 1.31
Reelin regulates neuronal progenitor migration in intact and epileptic hippocampus. J Neurosci (2007) 1.27
Proteomic analysis of protein changes developing in rat hippocampus after chronic antidepressant treatment: Implications for depressive disorders and future therapies. J Neurosci Res (2004) 1.23
Antidepressant-like effects of intracerebroventricular FGF2 in rats. Brain Res (2008) 1.22
Predictable chronic mild stress improves mood, hippocampal neurogenesis and memory. Mol Psychiatry (2009) 1.22
Impaired remote spatial memory after hippocampal lesions despite extensive training beginning early in life. Hippocampus (2005) 1.20
Kainic acid increases the proliferation of granule cell progenitors in the dentate gyrus of the adult rat. Brain Res (1998) 1.18
Hippocampal neurodegeneration, spontaneous seizures, and mossy fiber sprouting in the F344 rat model of temporal lobe epilepsy. J Neurosci Res (2006) 1.18
Newly born dentate granule neurons after pilocarpine-induced epilepsy have hilar basal dendrites with immature synapses. Epilepsy Res (2006) 1.18
Injury-induced alterations in CNS electrophysiology. Prog Brain Res (2007) 1.16
Relevance of seizure-induced neurogenesis in animal models of epilepsy to the etiology of temporal lobe epilepsy. Epilepsia (2007) 1.15
Decreased neuronal differentiation of newly generated cells underlies reduced hippocampal neurogenesis in chronic temporal lobe epilepsy. Hippocampus (2010) 1.13
A new chapter in the field of memory: adult hippocampal neurogenesis. Eur J Neurosci (2011) 1.12
Reelin controls granule cell migration in the dentate gyrus by acting on the radial glial scaffold. Cereb Cortex (2003) 1.11
Chronic antidepressant treatments increase basic fibroblast growth factor and fibroblast growth factor-binding protein in neurons. Neuropharmacology (2008) 1.10
Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density. Learn Mem (2011) 1.09
Progenitor proliferation in the adult hippocampus and substantia nigra induced by glial cell line-derived neurotrophic factor. Exp Neurol (2005) 1.09
Hippocampal neurotrophin levels after injury: Relationship to the age of the hippocampus at the time of injury. J Neurosci Res (2004) 1.09
Overexpression of Reelin prevents the manifestation of behavioral phenotypes related to schizophrenia and bipolar disorder. Neuropsychopharmacology (2011) 1.08
Cognitive role of neurogenesis in depression and antidepressant treatment. Neuroscientist (2008) 1.06
Plasticity of hippocampal stem/progenitor cells to enhance neurogenesis in response to kainate-induced injury is lost by middle age. Aging Cell (2008) 1.05
Increased dentate neurogenesis after grafting of glial restricted progenitors or neural stem cells in the aging hippocampus. Stem Cells (2007) 1.03
Hippocampal volume and mood disorders after traumatic brain injury. Biol Psychiatry (2006) 1.02
Enhanced production and dendritic growth of new dentate granule cells in the middle-aged hippocampus following intracerebroventricular FGF-2 infusions. Eur J Neurosci (2007) 1.02
Nuclear calcium-VEGFD signaling controls maintenance of dendrite arborization necessary for memory formation. Neuron (2011) 1.01
FGF2 gene transfer restores hippocampal functions in mouse models of Alzheimer's disease and has therapeutic implications for neurocognitive disorders. Proc Natl Acad Sci U S A (2011) 1.00
Hippocampal neurotrophin levels in a kainate model of temporal lobe epilepsy: a lack of correlation between brain-derived neurotrophic factor content and progression of aberrant dentate mossy fiber sprouting. J Neurochem (2003) 0.99
Expression of GDNF transgene in astrocytes improves cognitive deficits in aged rats. Neurobiol Aging (2007) 0.99
Vulnerability of hippocampal GABA-ergic interneurons to kainate-induced excitotoxic injury during old age. J Cell Mol Med (2009) 0.98
Reelin-mediated signaling in neuropsychiatric and neurodegenerative diseases. Prog Neurobiol (2010) 0.96
Structural and functional correlates of unilateral mesial temporal lobe spatial memory impairment. Brain (2008) 0.95
Subventricular zone neural progenitors from rapid brain autopsies of elderly subjects with and without neurodegenerative disease. J Comp Neurol (2009) 0.94
Dorsal vs ventral hippocampal neurogenesis: implications for cognition and mood. Neuropsychopharmacology (2011) 0.93
Long-term expansion of adult human brain subventricular zone precursors. Neurosurgery (2008) 0.92
Extrasynaptic GABAA receptor activation reverses recognition memory deficits in an animal model of schizophrenia. Psychopharmacology (Berl) (2010) 0.88
Impaired behavioural flexibility and memory in mice lacking GDNF family receptor alpha2. Eur J Neurosci (2004) 0.87
Performance on spatial working memory tasks after dorsal or ventral hippocampal lesions and adjacent damage to the subiculum. Behav Neurosci (2006) 0.85
Insights into neurogenesis and aging: potential therapy for degenerative disease? Future Neurol (2010) 0.84
Reelin as a putative vulnerability factor for depression: examining the depressogenic effects of repeated corticosterone in heterozygous reeler mice. Neuropharmacology (2010) 0.84
Differential effects of injury severity on cognition and cellular pathology after contusive brain trauma in the immature rat. J Neurotrauma (2011) 0.83
The role of the hippocampus in long-term memory: is it memory store or comparator? J Integr Neurosci (2008) 0.82
Enhanced cell survival in fetal hippocampal suspension transplants grafted to adult rat hippocampus following kainate lesions: a three-dimensional graft reconstruction study. Neuroscience (1995) 0.82
Acute systemic fibroblast growth factor-2 enhances long-term memory in developing rats. Neurobiol Learn Mem (2009) 0.81
Excitatory synaptic potentials in kainic acid-denervated rat CA1 pyramidal neurons. J Neurosci (1991) 0.81
Neural stem cell grafting in an animal model of chronic temporal lobe epilepsy. Curr Protoc Stem Cell Biol (2011) 0.81
Reelin, a marker of stress resilience in depression and psychosis. Neuropsychopharmacology (2011) 0.79
Efficacy of doublecortin as a marker to analyse the absolute number and dendritic growth of newly generated neurons in the adult dentate gyrus. Eur J Neurosci (2004) 2.86
Aging does not alter the number or phenotype of putative stem/progenitor cells in the neurogenic region of the hippocampus. Neurobiol Aging (2006) 1.89
Newly born cells in the ageing dentate gyrus display normal migration, survival and neuronal fate choice but endure retarded early maturation. Eur J Neurosci (2005) 1.74
Clinical prospects for neural grafting therapy for hippocampal lesions and epilepsy. Neurosurgery (2003) 1.54
The window and mechanisms of major age-related decline in the production of new neurons within the dentate gyrus of the hippocampus. Aging Cell (2006) 1.52
Chronic temporal lobe epilepsy is associated with severely declined dentate neurogenesis in the adult hippocampus. Neurobiol Dis (2004) 1.33
Medial ganglionic eminence-derived neural stem cell grafts ease spontaneous seizures and restore GDNF expression in a rat model of chronic temporal lobe epilepsy. Stem Cells (2010) 1.31
Chronic alcohol exposure reduces hippocampal neurogenesis and dendritic growth of newborn neurons. Eur J Neurosci (2005) 1.31
Progress in neuroprotective strategies for preventing epilepsy. Prog Neurobiol (2007) 1.24
Hippocampal neurodegeneration, spontaneous seizures, and mossy fiber sprouting in the F344 rat model of temporal lobe epilepsy. J Neurosci Res (2006) 1.18
Hippocampal neurogenesis and neural stem cells in temporal lobe epilepsy. Epilepsy Behav (2008) 1.14
Aging in the rat hippocampus is associated with widespread reductions in the number of glutamate decarboxylase-67 positive interneurons but not interneuron degeneration. J Neurochem (2004) 1.14
Decreased neuronal differentiation of newly generated cells underlies reduced hippocampal neurogenesis in chronic temporal lobe epilepsy. Hippocampus (2010) 1.13
Grafting of striatal precursor cells into hippocampus shortly after status epilepticus restrains chronic temporal lobe epilepsy. Exp Neurol (2008) 1.08
Plasticity of hippocampal stem/progenitor cells to enhance neurogenesis in response to kainate-induced injury is lost by middle age. Aging Cell (2008) 1.05
Increased dentate neurogenesis after grafting of glial restricted progenitors or neural stem cells in the aging hippocampus. Stem Cells (2007) 1.03
Enhanced production and dendritic growth of new dentate granule cells in the middle-aged hippocampus following intracerebroventricular FGF-2 infusions. Eur J Neurosci (2007) 1.02
Implications of decreased hippocampal neurogenesis in chronic temporal lobe epilepsy. Epilepsia (2008) 1.02
Disruption of the blood-brain barrier and neuronal cell death in cingulate cortex, dentate gyrus, thalamus, and hypothalamus in a rat model of Gulf-War syndrome. Neurobiol Dis (2002) 1.02
Strategies for promoting anti-seizure effects of hippocampal fetal cells grafted into the hippocampus of rats exhibiting chronic temporal lobe epilepsy. Neurobiol Dis (2007) 1.01
Status epilepticus during old age is not associated with enhanced hippocampal neurogenesis. Hippocampus (2008) 0.95
Nestin expression in hippocampal astrocytes after injury depends on the age of the hippocampus. Glia (2004) 0.94
Acute Seizures in Old Age Leads to a Greater Loss of CA1 Pyramidal Neurons, an Increased Propensity for Developing Chronic TLE and a Severe Cognitive Dysfunction. Aging Dis (2011) 0.93
Fetal hippocampal CA3 cell grafts enriched with FGF-2 and BDNF exhibit robust long-term survival and integration and suppress aberrant mossy fiber sprouting in the injured middle-aged hippocampus. Neurobiol Dis (2005) 0.92
Administration of TSG-6 improves memory after traumatic brain injury in mice. Neurobiol Dis (2013) 0.90
Is exposure to enriched environment beneficial for functional post-lesional recovery in temporal lobe epilepsy? Neurosci Biobehav Rev (2007) 0.89
Differential susceptibility of interneurons expressing neuropeptide Y or parvalbumin in the aged hippocampus to acute seizure activity. PLoS One (2011) 0.88
Mood and memory deficits in a model of Gulf War illness are linked with reduced neurogenesis, partial neuron loss, and mild inflammation in the hippocampus. Neuropsychopharmacology (2013) 0.88
Prenatal choline supplementation protects against postnatal neurotoxicity. J Neurosci (2002) 0.86
Fetal hippocampal CA3 cell grafts enriched with fibroblast growth factor-2 exhibit enhanced neuronal integration into the lesioned aging rat hippocampus in a kainate model of temporal lobe epilepsy. Hippocampus (2003) 0.85
Neural stem cell- and neurogenesis-related gene expression profiles in the young and aged dentate gyrus. Age (Dordr) (2013) 0.83
Prenatal dietary choline availability alters postnatal neurotoxic vulnerability in the adult rat. Neurosci Lett (2003) 0.83
Pretreatment of donor cells with FGF-2 enhances survival of fetal hippocampal CA3 cell transplants in the chronically lesioned young adult hippocampus. Exp Neurol (2003) 0.82
Neural stem cell grafting in an animal model of chronic temporal lobe epilepsy. Curr Protoc Stem Cell Biol (2011) 0.81
Survival of fetal hippocampal CA3 cell grafts in the middle-aged and aged hippocampus: effect of host age and deafferentation. J Neurosci Res (2002) 0.80
Could hippocampal neurogenesis be a future drug target for treating temporal lobe epilepsy? CNS Neurol Disord Drug Targets (2007) 0.79
A&D, a bridge between aging and age-related disease. Aging Dis (2010) 0.75