Published in Bioanalysis on December 01, 2012
A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis. Science (2004) 13.04
Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins. J Transl Med (2007) 2.90
Communicating with the public about emerging health threats: lessons from the Pre-Event Message Development Project. Am J Public Health (2008) 1.92
Anticoagulant counter ion impact on bioanalytical LC-MS/MS assays: results from discussions and experiments within the European Bioanalysis Forum. Bioanalysis (2011) 1.83
Smart sensors to network the world. Sci Am (2004) 1.77
Modeling liver fibrosis in rodents. Methods Mol Med (2005) 1.57
Effects of controlled discontinuation of long-term used antipsychotics on weight and metabolic parameters in individuals with intellectual disability. J Clin Psychopharmacol (2013) 1.38
Selection of a respiratory syncytial virus fusion inhibitor clinical candidate. 2. Discovery of a morpholinopropylaminobenzimidazole derivative (TMC353121). J Med Chem (2008) 1.21
2011 White paper on recent issues in bioanalysis and regulatory findings from audits and inspections. Bioanalysis (2011) 1.12
Effect of food on the pharmacokinetics of sunitinib malate (SU11248), a multi-targeted receptor tyrosine kinase inhibitor: results from a phase I study in healthy subjects. Anticancer Drugs (2006) 1.12
Synthesis of novel diarylpyrimidine analogues and their antiviral activity against human immunodeficiency virus type 1. J Med Chem (2005) 1.10
Anticoagulant counter ion impact on bioanalytical LC-MS/MS assay performance: additional validation required? Bioanalysis (2011) 1.09
Phenoconversion of cytochrome P450 2D6: the need for identifying the intermediate metabolizer genotype. J Clin Psychiatry (2013) 1.08
Darunavir concentrations in cerebrospinal fluid and blood in HIV-1-infected individuals. AIDS Res Hum Retroviruses (2009) 1.04
Which human metabolites have we MIST? Retrospective analysis, practical aspects, and perspectives for metabolite identification and quantification in pharmaceutical development. Chem Res Toxicol (2009) 1.01
Building the Global Bioanalysis Consortium - working towards a functional globally acceptable and harmonized guideline on bioanalytical method validation. Bioanalysis (2010) 0.98
Incurred sample reproducibility: views and recommendations by the European Bioanalysis Forum. Bioanalysis (2009) 0.95
Pharmacokinetics of sunitinib malate in subjects with hepatic impairment. Cancer Chemother Pharmacol (2010) 0.95
MMP-9 protein level does not reflect overall MMP activity in the airways of patients with COPD. Respir Med (2008) 0.94
Short duration aerosols of JNJ 2408068 (R170591) administered prophylactically or therapeutically protect cotton rats from experimental respiratory syncytial virus infection. Antiviral Res (2003) 0.92
European Bioanalysis Forum recommendation: scientific validation of quantification by accelerator mass spectrometry. Bioanalysis (2012) 0.91
The European Bioanalysis Forum community's evaluation, interpretation and implementation of the European Medicines Agency guideline on Bioanalytical Method Validation. Bioanalysis (2013) 0.91
Selection of a respiratory syncytial virus fusion inhibitor clinical candidate, part 1: improving the pharmacokinetic profile using the structure-property relationship. J Med Chem (2007) 0.91
Increased immunogenicity of recombinant Ad35-based malaria vaccine through formulation with aluminium phosphate adjuvant. Vaccine (2007) 0.90
Impact of recombinant adenovirus serotype 35 priming versus boosting of a Plasmodium falciparum protein: characterization of T- and B-cell responses to liver-stage antigen 1. Infect Immun (2008) 0.90
Matrix metalloproteinase expression and activity in human airway smooth muscle cells. Br J Pharmacol (2004) 0.90
c-Jun terminal kinase-2 gene deleted mice overexpress hemeoxygenase-1 and are protected from hepatic ischemia reperfusion injury. Transplantation (2009) 0.88
Physiological concentration of calcium inhibits elastase-induced cleavage of a functional recombinant fragment of surfactant protein D. Immunobiology (2010) 0.88
Blood stability testing: European Bioanalysis Forum view on current challenges for regulated bioanalysis. Bioanalysis (2011) 0.88
European Bioanalysis Forum recommendation on method establishment and bioanalysis of biomarkers in support of drug development. Bioanalysis (2012) 0.88
The association between cytochrome P450 2D6 genotype and prescription patterns of antipsychotic and antidepressant drugs in hospitalized psychiatric patients: a retrospective follow-up study. J Clin Psychopharmacol (2005) 0.88
Towards harmonized regulations for bioanalysis: moving forward! Bioanalysis (2010) 0.87
From evidence based medicine to mechanism based medicine. Reviewing the role of pharmacogenetics. Int J Clin Pharm (2011) 0.87
Request for global harmonization of the guidance for Bioanalytical Method Validation and sample analysis. Bioanalysis (2010) 0.85
EBF recommendation on the validation of bioanalytical methods for dried blood spots. Bioanalysis (2011) 0.85
Polymorphisms of the LEP- and LEPR gene and obesity in patients using antipsychotic medication. J Clin Psychopharmacol (2009) 0.84
Association of genetic variants of the histamine H1 and muscarinic M3 receptors with BMI and HbA1c values in patients on antipsychotic medication. Psychopharmacology (Berl) (2011) 0.83
Population pharmacokinetic model of fluvoxamine in rats: utility for application in animal behavioral studies. Eur J Pharm Sci (2006) 0.83
2010 white paper on recent issues in regulated bioanalysis & global harmonization of bioanalytical guidance. Bioanalysis (2010) 0.83
Risperidone-induced weight gain in referred children with autism spectrum disorders is associated with a common polymorphism in the 5-hydroxytryptamine 2C receptor gene. J Child Adolesc Psychopharmacol (2010) 0.82
A screening UHPLC-MS/MS method for the analysis of amyloid peptides in cerebrospinal fluid of preclinical species. Bioanalysis (2011) 0.81
Implementing dried blood spot sampling for clinical pharmacokinetic determinations: considerations from the IQ Consortium Microsampling Working Group. AAPS J (2014) 0.81
Association between the 1291-C/G polymorphism in the adrenergic α-2a receptor and the metabolic syndrome. J Clin Psychopharmacol (2010) 0.80
Combined HTR2C-LEP genotype as a determinant of obesity in patients using antipsychotic medication. J Clin Psychopharmacol (2010) 0.80
Assay formats: Recommendation for best practices and harmonization from the global bioanalysis consortium harmonization team. AAPS J (2013) 0.80
2014 White Paper on recent issues in bioanalysis: a full immersion in bioanalysis (Part 3 - LBA and immunogenicity). Bioanalysis (2014) 0.80
From evidence based medicine to mechanism based medicine. Reviewing the role of pharmacogenetics. Int J Clin Pharm (2010) 0.80
High-level expression from two independent expression cassettes in replication-incompetent adenovirus type 35 vector. J Gen Virol (2007) 0.80
Expression and immunogenicity of the Plasmodium falciparum circumsporozoite protein: the role of GPI signal sequence. Vaccine (2006) 0.79
New frontiers-accelerator mass spectrometry (AMS): Recommendation for best practices and harmonization from Global Bioanalysis Consortium Harmonization Team. AAPS J (2014) 0.79
Determinants of physical health parameters in individuals with intellectual disability who use long-term antipsychotics. Res Dev Disabil (2013) 0.79
Self-assembling PEG-p(CL-co-TMC) copolymers for oral delivery of poorly water-soluble drugs: a case study with risperidone. J Control Release (2005) 0.79
In-depth study of homogeneity in DBS using two different techniques: results from the EBF DBS-microsampling consortium. Bioanalysis (2013) 0.79
The effect of hematocrit on bioanalysis of DBS: results from the EBF DBS-microsampling consortium. Bioanalysis (2013) 0.79
LC-MS/MS of large molecules in a regulated bioanalytical environment - which acceptance criteria to apply? Bioanalysis (2013) 0.78
2013 White Paper on recent issues in bioanalysis: 'hybrid'--the best of LBA and LCMS. Bioanalysis (2013) 0.78
EBF and dried blood spots: from recommendations to potential resolution. Bioanalysis (2011) 0.78
The association between serotonin 2C receptor polymorphisms and weight gain and eating behavior in patients using mirtazapine: a prospective follow-up study. J Clin Psychopharmacol (2010) 0.78
Cross-national comparison of medication use in Australian and Dutch nursing homes. Age Ageing (2017) 0.77
Connecting strategies on dried blood spots. Bioanalysis (2010) 0.77
Pharmacokinetic interaction between simvastatin and fenofibrate with staggered and simultaneous dosing: Does it matter? J Clin Pharmacol (2014) 0.77
Food does not affect the pharmacokinetics of solifenacin, a new muscarinic receptor antagonist: results of a randomized crossover trial. Br J Clin Pharmacol (2004) 0.77
'Large Meets Small': connecting the bioanalytical community around peptide and protein bioanalysis with LC-MS(/MS). Bioanalysis (2012) 0.77
Conference report: Discussion on harmonization and globalization of bioanalytical guidances at the 19th International Reid Bioanalytical Forum. Bioanalysis (2011) 0.76
Validation of the rapid fluorescent focus inhibition test for rabies virus-neutralizing antibodies in clinical samples. Antimicrob Agents Chemother (2012) 0.76
2014 White Paper on recent issues in bioanalysis: a full immersion in bioanalysis (Part 2 - hybrid LBA/LCMS, ELN & regulatory agencies' input). Bioanalysis (2014) 0.76
Introduction to the proposals from the global bioanalysis consortium harmonization team. AAPS J (2014) 0.75
Effects of discontinuation of long-term used antipsychotics on prolactin and bone turnover markers in patients with intellectual disability. J Clin Psychopharmacol (2014) 0.75
European Bioanalysis Forum and the way forward towards harmonized regulations. Bioanalysis (2009) 0.75
Updates from the EBF DBS--microsampling consortium. Bioanalysis (2012) 0.75
'Less is More': defining modern bioanalysis. Bioanalysis (2012) 0.75
The association between cytochrome P450-2D6 genotype and prescription of antiparkinsonian drugs in hospitalized psychiatric patients using antipsychotics: a retrospective follow-up study. J Clin Psychopharmacol (2006) 0.75
From challenges to solutions. European Bioanalysis Forum 3rd Annual Open Symposium, Hesperia Towers, Barcelona, Spain, 1-3 December 2010. Bioanalysis (2011) 0.75
Combined HTR2C-LEP and HTR2C-LEPR genotypes as a determinant for obesity in patients without antipsychotic drugs. J Clin Psychopharmacol (2014) 0.75
New model for intravenous drug administration and blood sampling in the awake rat, designed to increase quality and throughput for in vivo pharmacokinetic analysis. J Pharmacol Toxicol Methods (2004) 0.75
Managing scientific, technical and regulatory innovation in regulated bioanalysis: a discussion paper from the European Bioanalysis Forum. Bioanalysis (2013) 0.75
Association between HTR2C polymorphisms and obesity in patients without antipsychotic drugs. J Clin Psychopharmacol (2012) 0.75
Association between the ROBO1 gene and body mass index in patients using antipsychotics. Psychiatr Genet (2011) 0.75
Solifenacin demonstrates high absolute bioavailability in healthy men. Drugs R D (2004) 0.75
IS addition in bioanalysis of DBS: results from the EBF DBS-microsampling consortium. Bioanalysis (2013) 0.75
Pharmacogenetic testing to predict antipsychotic-induced weight gain: a systematic review. Pharmacogenomics (2011) 0.75