Published in DNA Repair (Amst) on November 24, 2012
MSH3 polymorphisms and protein levels affect CAG repeat instability in Huntington's disease mice. PLoS Genet (2013) 1.02
EMAST is a Form of Microsatellite Instability That is Initiated by Inflammation and Modulates Colorectal Cancer Progression. Genes (Basel) (2015) 1.01
Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches. PLoS Genet (2013) 0.95
The MutSβ complex is a modulator of p53-driven tumorigenesis through its functions in both DNA double-strand break repair and mismatch repair. Oncogene (2013) 0.89
Expression levels of DNA replication and repair genes predict regional somatic repeat instability in the brain but are not altered by polyglutamine disease protein expression or age. Hum Mol Genet (2013) 0.84
Large expansion of CTG•CAG repeats is exacerbated by MutSβ in human cells. Sci Rep (2015) 0.82
Different roles of eukaryotic MutS and MutL complexes in repair of small insertion and deletion loops in yeast. PLoS Genet (2013) 0.82
Absence of MutSβ leads to the formation of slipped-DNA for CTG/CAG contractions at primate replication forks. DNA Repair (Amst) (2016) 0.79
Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration. J Clin Invest (2017) 0.76
A Delicate Balance Between Repair and Replication Factors Regulates Recombination Between Divergent DNA Sequences in Saccharomyces cerevisiae. Genetics (2015) 0.76
Abnormal base excision repair at trinucleotide repeats associated with diseases: a tissue-selective mechanism. Genes (Basel) (2013) 0.76
Ethidium Bromide Modifies The Agarose Electrophoretic Mobility of CAG•CTG Alternative DNA Structures Generated by PCR. Front Cell Neurosci (2017) 0.75
Functional amounts of dystrophin produced by skipping the mutated exon in the mdx dystrophic mouse. Nat Med (2003) 4.03
Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation. Proc Natl Acad Sci U S A (2004) 3.45
E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex. Genes Dev (2002) 3.12
Repeat instability as the basis for human diseases and as a potential target for therapy. Nat Rev Mol Cell Biol (2010) 3.09
RNA-mediated neurodegeneration caused by the fragile X premutation rCGG repeats in Drosophila. Neuron (2003) 2.81
Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells. Nat Genet (2002) 2.81
Somatic expansion behaviour of the (CTG)n repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins. Hum Mol Genet (2002) 2.48
Neuronal SMN expression corrects spinal muscular atrophy in severe SMA mice while muscle-specific SMN expression has no phenotypic effect. Hum Mol Genet (2008) 2.35
The disease-associated r(GGGGCC)n repeat from the C9orf72 gene forms tract length-dependent uni- and multimolecular RNA G-quadruplex structures. J Biol Chem (2013) 1.97
Slipped (CTG)*(CAG) repeats can be correctly repaired, escape repair or undergo error-prone repair. Nat Struct Mol Biol (2005) 1.97
CTG repeat instability and size variation timing in DNA repair-deficient mice. EMBO J (2003) 1.96
Mismatch repair gene Msh2 modifies the timing of early disease in Hdh(Q111) striatum. Hum Mol Genet (2003) 1.92
Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling. Genes Dev (2010) 1.88
CTCF cis-regulates trinucleotide repeat instability in an epigenetic manner: a novel basis for mutational hot spot determination. PLoS Genet (2008) 1.72
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130. Genes Dev (2004) 1.72
Msh3 is a limiting factor in the formation of intergenerational CTG expansions in DM1 transgenic mice. Hum Genet (2006) 1.55
Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M. Hum Mol Genet (2009) 1.47
Expanded CTG repeat demarcates a boundary for abnormal CpG methylation in myotonic dystrophy patient tissues. Hum Mol Genet (2010) 1.46
Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism. Chem Biol (2004) 1.45
Effect of pathogenic mis-sense mutations in lamin A on its interaction with emerin in vivo. J Cell Sci (2003) 1.44
Primary laminopathy fibroblasts display altered genome organization and apoptosis. Aging Cell (2007) 1.43
Long-term persistence of donor nuclei in a Duchenne muscular dystrophy patient receiving bone marrow transplantation. J Clin Invest (2002) 1.41
Triplet repeat DNA structures and human genetic disease: dynamic mutations from dynamic DNA. J Biosci (2002) 1.37
Replication fork dynamics and dynamic mutations: the fork-shift model of repeat instability. Trends Genet (2005) 1.33
Interruptions in the expanded ATTCT repeat of spinocerebellar ataxia type 10: repeat purity as a disease modifier? Am J Hum Genet (2005) 1.32
Determinants of R-loop formation at convergent bidirectionally transcribed trinucleotide repeats. Nucleic Acids Res (2010) 1.32
MSH2-dependent germinal CTG repeat expansions are produced continuously in spermatogonia from DM1 transgenic mice. Mol Cell Biol (2004) 1.30
A role for complexes of survival of motor neurons (SMN) protein with gemins and profilin in neurite-like cytoplasmic extensions of cultured nerve cells. Exp Cell Res (2005) 1.29
Targeted gene modification in mismatch-repair-deficient embryonic stem cells by single-stranded DNA oligonucleotides. Nucleic Acids Res (2003) 1.28
Replication inhibitors modulate instability of an expanded trinucleotide repeat at the myotonic dystrophy type 1 disease locus in human cells. Am J Hum Genet (2003) 1.24
Tissue- and age-specific DNA replication patterns at the CTG/CAG-expanded human myotonic dystrophy type 1 locus. Nat Struct Mol Biol (2010) 1.24
MSH2 ATPase domain mutation affects CTG*CAG repeat instability in transgenic mice. PLoS Genet (2009) 1.22
Huntington's and myotonic dystrophy hESCs: down-regulated trinucleotide repeat instability and mismatch repair machinery expression upon differentiation. Hum Mol Genet (2010) 1.21
A direct interaction between the survival motor neuron protein and p53 and its relationship to spinal muscular atrophy. J Biol Chem (2001) 1.20
Subtle gene modification in mouse ES cells: evidence for incorporation of unmodified oligonucleotides without induction of DNA damage. Nucleic Acids Res (2010) 1.20
Isolated short CTG/CAG DNA slip-outs are repaired efficiently by hMutSbeta, but clustered slip-outs are poorly repaired. Proc Natl Acad Sci U S A (2010) 1.20
Bidirectional transcription stimulates expansion and contraction of expanded (CTG)*(CAG) repeats. Hum Mol Genet (2010) 1.19
Muscleblind-like proteins: similarities and differences in normal and myotonic dystrophy muscle. Am J Pathol (2008) 1.17
Defective mRNA in myotonic dystrophy accumulates at the periphery of nuclear splicing speckles. Genes Cells (2007) 1.16
Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells. Oncogene (2002) 1.16
TMPyP4 porphyrin distorts RNA G-quadruplex structures of the disease-associated r(GGGGCC)n repeat of the C9orf72 gene and blocks interaction of RNA-binding proteins. J Biol Chem (2013) 1.15
Matrix metalloproteinase-1 associates with intracellular organelles and confers resistance to lamin A/C degradation during apoptosis. Am J Pathol (2005) 1.14
Genomic context drives SCA7 CAG repeat instability, while expressed SCA7 cDNAs are intergenerationally and somatically stable in transgenic mice. Hum Mol Genet (2003) 1.14
Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development. Dev Dyn (2010) 1.13
Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich's ataxia. Dis Model Mech (2012) 1.13
Emerin interacts in vitro with the splicing-associated factor, YT521-B. Eur J Biochem (2003) 1.12
The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exit. J Cell Biol (2010) 1.11
Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery. Genome Biol (2013) 1.11
Mutagenic roles of DNA "repair" proteins in antibody diversity and disease-associated trinucleotide repeat instability. DNA Repair (Amst) (2008) 1.09
Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy. J Clin Invest (2014) 1.08
In vitro (CTG)*(CAG) expansions and deletions by human cell extracts. J Biol Chem (2002) 1.06
Role of replication and CpG methylation in fragile X syndrome CGG deletions in primate cells. Am J Hum Genet (2004) 1.06
Learning from a paradox: recent insights into Fanconi anaemia through studying mouse models. Dis Model Mech (2013) 1.05
Generation of a mouse mutant by oligonucleotide-mediated gene modification in ES cells. Nucleic Acids Res (2006) 1.04
Molecular interaction between fukutin and POMGnT1 in the glycosylation pathway of alpha-dystroglycan. Biochem Biophys Res Commun (2006) 1.03
MSH3 polymorphisms and protein levels affect CAG repeat instability in Huntington's disease mice. PLoS Genet (2013) 1.02
Susceptibility of Msh2-deficient mice to inflammation-associated colorectal tumors. Cancer Res (2002) 1.02
Cytoplasmic CUG RNA foci are insufficient to elicit key DM1 features. PLoS One (2008) 1.01
Phase I study of dystrophin plasmid-based gene therapy in Duchenne/Becker muscular dystrophy. Hum Gene Ther (2004) 1.01
Strand bias in oligonucleotide-mediated dystrophin gene editing. Hum Mol Genet (2004) 1.00
Mitogen requirement for cell cycle progression in the absence of pocket protein activity. Cancer Cell (2005) 0.99
Absence of gemin5 from SMN complexes in nuclear Cajal bodies. BMC Cell Biol (2007) 0.98
Dynamic complexes of A-type lamins and emerin influence adipogenic capacity of the cell via nucleocytoplasmic distribution of beta-catenin. J Cell Sci (2009) 0.98
CpG methylation modifies the genetic stability of cloned repeat sequences. Genome Res (2002) 0.98
CTG/CAG repeat instability is modulated by the levels of human DNA ligase I and its interaction with proliferating cell nuclear antigen: a distinction between replication and slipped-DNA repair. J Biol Chem (2009) 0.97
The apparent absence of lamin B1 and emerin in many tissue nuclei is due to epitope masking. J Mol Histol (2005) 0.97
Expanded CUG repeats Dysregulate RNA splicing by altering the stoichiometry of the muscleblind 1 complex. J Biol Chem (2011) 0.97
Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches. PLoS Genet (2013) 0.95
Novel function of the retinoblastoma protein in fat: regulation of white versus brown adipocyte differentiation. Cell Cycle (2004) 0.95
Parameters of oligonucleotide-mediated gene modification in mouse ES cells. J Cell Mol Med (2009) 0.95
Analysis of exonic regions involved in nuclear localization, splicing activity, and dimerization of Muscleblind-like-1 isoforms. J Biol Chem (2011) 0.94
Msh2 deficiency does not contribute to cisplatin resistance in mouse embryonic stem cells. Oncogene (2004) 0.94
ApoE isoform-specific regulation of regeneration in the peripheral nervous system. Hum Mol Genet (2011) 0.93
Maternal germline-specific effect of DNA ligase I on CTG/CAG instability. Hum Mol Genet (2011) 0.92
The nucleotide sequence, DNA damage location, and protein stoichiometry influence the base excision repair outcome at CAG/CTG repeats. Biochemistry (2012) 0.91
Fidelity of primate cell repair of a double-strand break within a (CTG).(CAG) tract. Effect of slipped DNA structures. J Biol Chem (2003) 0.90
Effect of CAT or AGG interruptions and CpG methylation on nucleosome assembly upon trinucleotide repeats on spinocerebellar ataxia, type 1 and fragile X syndrome. J Biol Chem (2004) 0.90
DNA mismatch repair deficiency stimulates N-ethyl-N-nitrosourea-induced mutagenesis and lymphomagenesis. Cancer Res (2003) 0.89
Fancf-deficient mice are prone to develop ovarian tumours. J Pathol (2011) 0.89
The SMN interactome includes Myb-binding protein 1a. J Proteome Res (2010) 0.88
The human cruciform-binding protein, CBP, is involved in DNA replication and associates in vivo with mammalian replication origins. J Biol Chem (2002) 0.87
Slipped (CTG).(CAG) repeats of the myotonic dystrophy locus: surface probing with anti-DNA antibodies. J Mol Biol (2003) 0.87
High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines. Hum Mol Genet (2013) 0.86
Check, double check: the G2 barrier to cancer. Cell Cycle (2006) 0.86
Characterization of MSH2 variants by endogenous gene modification in mouse embryonic stem cells. Hum Mutat (2011) 0.86
The ATTCT repeats of spinocerebellar ataxia type 10 display strong nucleosome assembly which is enhanced by repeat interruptions. Gene (2008) 0.86