Effects of fibrinogen concentrate as first-line therapy during major aortic replacement surgery: a randomized, placebo-controlled trial.

PubWeight™: 2.08‹?› | Rank: Top 2%

🔗 View Article (PMID 23249928)

Published in Anesthesiology on January 01, 2013

Authors

Niels Rahe-Meyer1, Cristina Solomon, Alexander Hanke, Dirk S Schmidt, Dietrich Knoerzer, Gerald Hochleitner, Benny Sørensen, Christian Hagl, Maximilian Pichlmaier

Author Affiliations

1: Clinic for Anesthesiology and Intensive Care Medicine, Franziskus Hospital, Bielefeld, Germany. niels.rahe-meyer@franziskus.de

Articles citing this

Time course of haemostatic effects of fibrinogen concentrate administration in aortic surgery. Br J Anaesth (2013) 1.86

No evidence to support a priming strategy with FFP in infants. Eur J Pediatr (2014) 1.08

Estimation of plasma fibrinogen levels based on hemoglobin, base excess and Injury Severity Score upon emergency room admission. Crit Care (2013) 1.00

Trauma hemostasis and oxygenation research position paper on remote damage control resuscitation: definitions, current practice, and knowledge gaps. Shock (2014) 1.00

Thrombelastography (TEG®): practical considerations on its clinical use in trauma resuscitation. Scand J Trauma Resusc Emerg Med (2013) 0.99

Fibrinogen concentrate administration attributes to significant reductions of blood loss and transfusion requirements in thoracic aneurysm repair. J Cardiothorac Surg (2014) 0.87

Randomized, double-blinded, placebo-controlled trial of fibrinogen concentrate supplementation after complex cardiac surgery. J Am Heart Assoc (2015) 0.85

Fluid overload is associated with increases in length of stay and hospital costs: pooled analysis of data from more than 600 US hospitals. Clinicoecon Outcomes Res (2013) 0.83

Theoretical modelling of fibrinogen supplementation with therapeutic plasma, cryoprecipitate, or fibrinogen concentrate. Br J Anaesth (2014) 0.81

Over 50 Years of Fibrinogen Concentrate. Clin Appl Thromb Hemost (2015) 0.81

Impact of fibrinogen concentrate alone or with prothrombin complex concentrate (+/- fresh frozen plasma) on plasma fibrinogen level and fibrin-based clot strength (FIBTEM) in major trauma: a retrospective study. Scand J Trauma Resusc Emerg Med (2013) 0.81

TEG®- or ROTEM®-based individualized goal-directed coagulation algorithms: don't wait--act now! Crit Care (2014) 0.80

Endogenous thrombin potential following hemostatic therapy with 4-factor prothrombin complex concentrate: a 7-day observational study of trauma patients. Crit Care (2014) 0.80

Cryoprecipitate therapy. Br J Anaesth (2014) 0.80

Reducing transfusion requirements in liver transplantation. World J Transplant (2015) 0.78

Fibrinogen concentrate as first-line therapy in aortic surgery reduces transfusion requirements in patients with platelet counts over or under 100×10(9)/L. Blood Transfus (2014) 0.78

Administration of fibrinogen concentrate for refractory bleeding in massively transfused, non-trauma patients with coagulopathy: a retrospective study with comparator group. BMC Anesthesiol (2014) 0.78

Perioperatively acquired disorders of coagulation. Curr Opin Anaesthesiol (2015) 0.77

Fibrinogen concentrate and allogeneic blood transfusion in high-risk surgery. Anesthesiology (2013) 0.76

Randomized evaluation of fibrinogen vs placebo in complex cardiovascular surgery (REPLACE): a double-blind phase III study of haemostatic therapy. Br J Anaesth (2016) 0.75

Factor XIII Deficiency and Thrombocytopenia Are Frequent Modulators of Postoperative Clot Firmness in a Surgical Intensive Care Unit. Transfus Med Hemother (2017) 0.75

Use of lyophilized fibrinogen concentrate in cardiac surgery: a systematic review. Heart Lung Vessel (2015) 0.75

Fibrinogen levels in trauma patients during the first seven days after fibrinogen concentrate therapy: a retrospective study. Scand J Trauma Resusc Emerg Med (2016) 0.75

Updates on coagulation management in cardiac surgery. J Tehran Heart Cent (2014) 0.75

Factors affecting postoperative blood loss in children undergoing cardiac surgery. J Cardiothorac Surg (2014) 0.75

Is viscoelastic coagulation monitoring with ROTEM or TEG validated? Scand J Clin Lab Invest (2016) 0.75

Haemostatic management for aortic valve replacement in a patient with advanced liver disease. World J Clin Cases (2014) 0.75

Fibrinogen concentrate versus placebo for treatment of postpartum haemorrhage: study protocol for a randomised controlled trial. Trials (2015) 0.75

Management of postpartum haemorrhage. F1000Res (2016) 0.75

Rapid measurement of fibrinogen concentration in whole blood using a steel ball coagulometer. J Trauma Acute Care Surg (2015) 0.75

Thromboelastometry guided fibrinogen replacement therapy in cardiac surgery: a retrospective observational study. J Anesth (2016) 0.75

Intraoperative care for aortic surgery using circulatory arrest. J Thorac Dis (2017) 0.75

Articles by these authors

Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology. Eur J Anaesthesiol (2013) 4.04

The safety of moderate hypothermic lower body circulatory arrest with selective cerebral perfusion: a propensity score analysis. J Thorac Cardiovasc Surg (2007) 3.08

Cryopreserved human allografts (homografts) for the management of graft infections in the ascending aortic position extending to the arch. Eur J Cardiothorac Surg (2012) 2.70

Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM)-guided administration of fibrinogen concentrate and prothrombin complex concentrate. Crit Care (2010) 2.47

A comparison of fibrinogen measurement methods with fibrin clot elasticity assessed by thromboelastometry, before and after administration of fibrinogen concentrate in cardiac surgery patients. Transfusion (2011) 2.34

Long-term results after aortic valve-sparing operation (David I). Eur J Cardiothorac Surg (2012) 2.16

Methylene blue: the drug of choice for catecholamine-refractory vasoplegia after cardiopulmonary bypass? J Thorac Cardiovasc Surg (2003) 2.14

Total aortic arch replacement with a novel four-branched frozen elephant trunk graft: first-in-man results. Eur J Cardiothorac Surg (2012) 2.11

Long-term cardiac allograft valves after heart transplant are functionally and structurally preserved, in contrast to homografts and bioprostheses. J Heart Valve Dis (2006) 2.04

Ascending aortic cannulation in acute aortic dissection type A: the Hannover experience. Eur J Cardiothorac Surg (2008) 1.80

Elephant trunk procedure 27 years after Borst: what remains and what is new? Eur J Cardiothorac Surg (2011) 1.73

Sutureless Perceval S aortic valve replacement: a multicenter, prospective pilot trial. J Heart Valve Dis (2009) 1.70

Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy. Crit Care (2011) 1.66

Total aortic arch replacement with the frozen elephant trunk technique: 10-year follow-up single-centre experience. Eur J Cardiothorac Surg (2013) 1.61

Cardiac retransplantation: is it justified in times of critical donor organ shortage? Long-term single-center experience. Eur J Cardiothorac Surg (2008) 1.54

Clinical effectiveness of fresh frozen plasma compared with fibrinogen concentrate: a systematic review. Crit Care (2011) 1.52

Isolated surgical aortic valve replacement after previous coronary artery bypass grafting with patent grafts: is this old-fashioned technique obsolete? Eur J Cardiothorac Surg (2008) 1.51

The impact of deep and moderate body temperatures on end-organ function during hypothermic circulatory arrest. Eur J Cardiothorac Surg (2011) 1.51

FIBTEM provides early prediction of massive transfusion in trauma. Crit Care (2011) 1.48

Diagnostic performance and therapeutic consequence of thromboelastometry activated by kaolin versus a panel of specific reagents. Anesthesiology (2011) 1.48

Early and individualized goal-directed therapy for trauma-induced coagulopathy. Scand J Trauma Resusc Emerg Med (2012) 1.46

Hypothermic circulatory arrest with moderate, deep or profound hypothermic selective antegrade cerebral perfusion: which temperature provides best brain protection? Eur J Cardiothorac Surg (2006) 1.44

Solulin increases clot stability in whole blood from humans and dogs with hemophilia. Blood (2012) 1.44

Treatment of patients with recurrent or persistent infection of cardiac implantable electronic devices. Europace (2010) 1.43

The effects of fibrinogen levels on thromboelastometric variables in the presence of thrombocytopenia. Anesth Analg (2009) 1.43

The frozen elephant trunk technique: a new treatment for thoracic aortic aneurysms. J Thorac Cardiovasc Surg (2003) 1.42

Whole blood coagulation in children with thrombocytopenia and the response to platelet replacement, recombinant factor VIIa, and a potent factor VIIa analogue. Br J Haematol (2008) 1.41

Thromboelastometry-guided administration of fibrinogen concentrate for the treatment of excessive intraoperative bleeding in thoracoabdominal aortic aneurysm surgery. J Thorac Cardiovasc Surg (2009) 1.41

Fibrinogen concentrate therapy guided by thromboelastometry as an alternative to fresh frozen plasma in major vascular surgery. J Cardiothorac Vasc Anesth (2011) 1.39

International normalised ratio (INR) measured on the CoaguChek S and XS compared with the laboratory for determination of precision and accuracy. Thromb Haemost (2009) 1.39

Hypothermic circulatory arrest with selective antegrade cerebral perfusion in ascending aortic and aortic arch surgery: a risk factor analysis for adverse outcome in 501 patients. J Thorac Cardiovasc Surg (2008) 1.35

Evolving strategies for treatment of acute aortic dissection type A. Circulation (2004) 1.20

Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model. Exp Neurol (2009) 1.18

Efficacy and safety of subcutaneous vivaglobin® replacement therapy in previously untreated patients with primary immunodeficiency: a prospective, multicenter study. J Clin Immunol (2011) 1.18

Platelet function following trauma. A multiple electrode aggregometry study. Thromb Haemost (2011) 1.15

Aortic valve reimplantation in ascending aortic aneurysm: risk factors for early valve failure. Ann Thorac Surg (2002) 1.15

Feasibility of second-generation bioresorbable vascular scaffold implantation in complex anatomical and clinical scenarios. Clin Res Cardiol (2014) 1.14

Aortic root surgery in Marfan syndrome: Comparison of aortic valve-sparing reimplantation versus composite grafting. J Thorac Cardiovasc Surg (2004) 1.14

Decade of aortic valve sparing reimplantation: are we pushing the limits too far? Circulation (2005) 1.13

Ethnic diversity and immunological barriers in heart transplantation. J Am Coll Cardiol (2014) 1.08

Fibrinogen estimates are influenced by methods of measurement and hemodilution with colloid plasma expanders. Transfusion (2010) 1.08

Surgical treatment of aberrant right subclavian artery (arteria lusoria) aneurysm using three different methods. Ann Thorac Surg (2006) 1.05

Intrapericardial migration of dislodged sternal struts as late complication of open pectus excavatum repairs. J Cardiothorac Surg (2011) 1.05

Fibrinogen concentrate reduces intraoperative bleeding when used as first-line hemostatic therapy during major aortic replacement surgery: results from a randomized, placebo-controlled trial. J Thorac Cardiovasc Surg (2013) 1.05

Edwards Sapien XT valve placement as treatment option for aortic regurgitation after transfemoral CoreValve implantation: a multicenter experience. Clin Res Cardiol (2013) 1.03

Dose-proportional intraindividual single- and repeated-dose pharmacokinetics of roflumilast, an oral, once-daily phosphodiesterase 4 inhibitor. J Clin Pharmacol (2007) 1.02

Eight-year experience with cryopreserved arterial homografts for the in situ reconstruction of abdominal aortic infections. J Vasc Surg (2010) 1.01

The frozen elephant trunk technique for treatment of thoracic aortic aneurysms. Ann Thorac Surg (2007) 1.01

A smooth transition protocol for patients with multifocal motor neuropathy going from intravenous to subcutaneous immunoglobulin therapy: an open-label proof-of-concept study. J Peripher Nerv Syst (2011) 1.01

Ten-year results of a randomized trial comparing tacrolimus versus cyclosporine a in combination with mycophenolate mofetil after heart transplantation. Transplantation (2013) 1.01

Aortic valve-sparing operation in Marfan syndrome: what do we know after a decade? Ann Thorac Surg (2007) 1.01

Fibrin formation is more impaired than thrombin generation and platelets immediately following cardiac surgery. Thromb Res (2011) 0.98

Thromboelastometric (ROTEM) findings in patients suffering from isolated severe traumatic brain injury. J Neurotrauma (2011) 0.97

Parallel use of by-passing agents in haemophilia with inhibitors: a critical review. Br J Haematol (2011) 0.97

Lymphoscintigraphic localization of a high-output chylus leak after bilateral lung transplantation. J Heart Lung Transplant (2010) 0.96

Valve-sparing aortic root reconstruction in patients with significant aortic insufficiency. Ann Thorac Surg (2002) 0.96

Steady-state pharmacokinetics of roflumilast and roflumilast N-oxide in patients with mild and moderate liver cirrhosis. Clin Pharmacokinet (2007) 0.95

An evaluation of cyclooxygenase-1 inhibition before coronary artery surgery: aggregometry versus patient self-reporting. Anesth Analg (2008) 0.95

Gender does matter: gender-specific outcome analysis of 67,855 heart transplants. Thorac Cardiovasc Surg (2012) 0.94

Daptomycin as supportive treatment option in patients developing mediastinitis after open cardiac surgery. J Cardiothorac Surg (2012) 0.93

Assessment of lung ventilation by MR imaging: current status and future perspectives. Eur Radiol (2002) 0.93

Thrombin generation and whole blood viscoelastic assays in the management of hemophilia: current state of art and future perspectives. Blood (2013) 0.93

Is treatment of acute type A aortic dissection in septuagenarians justifiable? Asian Cardiovasc Thorac Ann (2008) 0.91

Fibrinogen concentrate--a potential universal hemostatic agent. Expert Opin Biol Ther (2009) 0.89

Lung transplantation with lungs from donors fifty years of age and older. J Thorac Cardiovasc Surg (2005) 0.89

Immediate surgical coronary revascularisation in patients presenting with acute myocardial infarction. J Cardiothorac Surg (2013) 0.88

Acute type B aortic dissection: surgical therapy. Ann Thorac Surg (2002) 0.87

Severe pediatric blunt trauma--successful ROTEM-guided hemostatic therapy with fibrinogen concentrate and no administration of fresh frozen plasma or platelets. Clin Appl Thromb Hemost (2012) 0.87

Haemostatic therapy in coronary artery bypass graft patients with decreased platelet function: comparison of fibrinogen concentrate with allogeneic blood products. Scand J Clin Lab Invest (2012) 0.87

Minimally invasive aortic valve replacement with self-anchoring Perceval valve. J Heart Valve Dis (2013) 0.86

Heart-lung and lung transplantation in grown-up congenital heart disease: long-term single centre experience. Eur J Cardiothorac Surg (2007) 0.86

High-dose fibrinogen concentrate for haemostatic therapy of a major trauma patient with recent clopidogrel and aspirin intake. Scand J Clin Lab Invest (2010) 0.86

Recovery of fibrinogen concentrate after intraosseous application is equivalent to the intravenous route in a porcine model of hemodilution. J Trauma Acute Care Surg (2014) 0.85

Comparative assessment of coagulation changes induced by two different types of heart-lung machine. Artif Organs (2009) 0.85

The frozen elephant trunk technique for the treatment of extensive thoracic aortic aneurysms: operative results and follow-up. Eur J Cardiothorac Surg (2005) 0.85

Percutaneous extracorporeal life support for patients in therapy refractory cardiogenic shock: initial results of an interdisciplinary team. Interact Cardiovasc Thorac Surg (2013) 0.84

Results of valve-sparing aortic root reconstruction in 158 consecutive patients. Ann Thorac Surg (2002) 0.84

The first fifty consecutive Bentall operations with a prefabricated tissue-valved aortic conduit: a single-center experience. J Heart Valve Dis (2010) 0.84

Peculiar whole blood rotation thromboelastometry (Rotem) profile in 40 sideropenic anaemia patients. Thromb Haemost (2008) 0.84

Less impairment of hemostasis and reduced blood loss in pigs after resuscitation from hemorrhagic shock using the small-volume concept with hypertonic saline/hydroxyethyl starch as compared to administration of 4% gelatin or 6% hydroxyethyl starch solution. Anesth Analg (2008) 0.84

The gut-first approach for repair of Crawford extent III thoracoabdominal aortic aneurysms. J Thorac Cardiovasc Surg (2003) 0.84

Comparison of whole blood fibrin-based clot tests in thrombelastography and thromboelastometry. Anesth Analg (2012) 0.83

Less-invasive perfusion techniques may improve outcome in thoracoabdominal aortic surgery. J Thorac Cardiovasc Surg (2010) 0.83