Population structuring of multi-copy, antigen-encoding genes in Plasmodium falciparum.

PubWeight™: 0.95‹?› | Rank: Top 15%

🔗 View Article (PMC 3524794)

Published in Elife on December 18, 2012

Authors

Yael Artzy-Randrup1, Mary M Rorick, Karen Day, Donald Chen, Andrew P Dobson, Mercedes Pascual

Author Affiliations

1: Department of Ecology and Evolutionary Biology , Howard Hughes Medical Institute and the University of Michigan , Ann Arbor , United States.

Articles cited by this

How clonal are bacteria? Proc Natl Acad Sci U S A (1993) 18.19

The pathogenic basis of malaria. Nature (2002) 10.44

Adult and child malaria mortality in India: a nationally representative mortality survey. Lancet (2010) 7.89

Acquired immunity to malaria. Clin Microbiol Rev (2009) 6.24

Population genetics of pathogenic bacteria. Microb Pathog (1987) 5.59

Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria. Nat Med (1998) 5.41

Malaria pathogenesis. Science (1994) 4.76

A genome-wide map of diversity in Plasmodium falciparum. Nat Genet (2006) 4.50

Mating patterns in malaria parasite populations of Papua New Guinea. Science (1995) 4.40

The maintenance of strain structure in populations of recombining infectious agents. Nat Med (1996) 4.31

Sample sizes required to detect linkage disequilibrium between two or three loci. Theor Popul Biol (1975) 4.15

A clonal theory of parasitic protozoa: the population structures of Entamoeba, Giardia, Leishmania, Naegleria, Plasmodium, Trichomonas, and Trypanosoma and their medical and taxonomical consequences. Proc Natl Acad Sci U S A (1990) 4.07

Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparum. Nature (2000) 3.90

Antigenic variation in Plasmodium falciparum. Annu Rev Microbiol (2008) 3.10

High recombination rate in natural populations of Plasmodium falciparum. Proc Natl Acad Sci U S A (1999) 3.03

Antigenic diversity and the transmission dynamics of Plasmodium falciparum. Science (1994) 2.71

Antibody recognition of Plasmodium falciparum erythrocyte surface antigens in Kenya: evidence for rare and prevalent variants. Infect Immun (1999) 2.62

Transient cross-reactive immune responses can orchestrate antigenic variation in malaria. Nature (2004) 2.56

Common strategies for antigenic variation by bacterial, fungal and protozoan pathogens. Nat Rev Microbiol (2009) 2.54

Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs. Nat Genet (2010) 2.48

Cross-species interactions between malaria parasites in humans. Science (2000) 2.43

Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children. Proc Natl Acad Sci U S A (2012) 2.17

Population structure of pathogens: the role of immune selection. Parasitol Today (1999) 2.07

A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells. Proc Natl Acad Sci U S A (2012) 1.99

Antibodies to variable Plasmodium falciparum-infected erythrocyte surface antigens are associated with protection from novel malaria infections. Immunol Lett (2000) 1.89

The clonal theory of parasitic protozoa: 12 years on. Trends Parasitol (2002) 1.88

Population genomics of the immune evasion (var) genes of Plasmodium falciparum. PLoS Pathog (2007) 1.74

Var gene diversity in Plasmodium falciparum is generated by frequent recombination events. Mol Biochem Parasitol (2000) 1.67

Role of selection in the emergence of lineages and the evolution of virulence in Neisseria meningitidis. Proc Natl Acad Sci U S A (2008) 1.63

Antigenic variation in Plasmodium falciparum: gene organization and regulation of the var multigene family. Eukaryot Cell (2007) 1.58

Age- and species-specific duration of infection in asymptomatic malaria infections in Papua New Guinea. Parasitology (2000) 1.46

Antigenic variation in Plasmodium falciparum malaria involves a highly structured switching pattern. PLoS Pathog (2011) 1.45

Detection of genome-wide polymorphisms in the AT-rich Plasmodium falciparum genome using a high-density microarray. BMC Genomics (2008) 1.38

Targets of antibodies against Plasmodium falciparum-infected erythrocytes in malaria immunity. J Clin Invest (2012) 1.31

High recombination rates and hotspots in a Plasmodium falciparum genetic cross. Genome Biol (2011) 1.27

Prognostic indicators of life-threatening malaria are associated with distinct parasite variant antigen profiles. Sci Transl Med (2012) 1.27

Cross-species regulation of Plasmodium parasitemia in semi-immune children from Papua New Guinea. Trends Parasitol (2003) 1.25

An approach to classifying sequence tags sampled from Plasmodium falciparum var genes. Mol Biochem Parasitol (2007) 1.21

A strain theory of malaria transmission. Parasitol Today (1994) 1.15

Generating uniformly distributed random networks. Phys Rev E Stat Nonlin Soft Matter Phys (2005) 1.14

Within-host dynamics of antigenic variation. Infect Genet Evol (2006) 1.11

Long-term evolution of antigen repertoires among carried meningococci. Proc Biol Sci (2010) 1.08

A model for the sequential dominance of antigenic variants in African trypanosome infections. Proc Biol Sci (1999) 1.08

Cross-species regulation of malaria parasitaemia in the human host. Curr Opin Microbiol (2002) 1.03

A theoretical framework for the immunoepidemiology of Plasmodium falciparum malaria. Parasite Immunol (1994) 1.02

A molecular epidemiological study of var gene diversity to characterize the reservoir of Plasmodium falciparum in humans in Africa. PLoS One (2011) 0.98

Variant surface antigens, virulence genes and the pathogenesis of malaria. Trends Parasitol (2004) 0.96

Inferring malaria parasite population structure from serological networks. Proc Biol Sci (2009) 0.89

Role of stochastic processes in maintaining discrete strain structure in antigenically diverse pathogen populations. Proc Natl Acad Sci U S A (2011) 0.88

How selection forces dictate the variant surface antigens used by malaria parasites. J R Soc Interface (2011) 0.79

Antigenic diversity and the transmission dynamics of Plasmodium falciparum: the clonality/sexuality debate revisited. Parasitol Today (1994) 0.78

Articles by these authors

Climate warming and disease risks for terrestrial and marine biota. Science (2002) 9.79

Introduced species and their missing parasites. Nature (2003) 6.64

Projected impacts of climate and land-use change on the global diversity of birds. PLoS Biol (2007) 6.10

Epochal evolution shapes the phylodynamics of interpandemic influenza A (H3N2) in humans. Science (2006) 6.01

Seasonality and the dynamics of infectious diseases. Ecol Lett (2006) 5.84

Anticipating critical transitions. Science (2012) 4.64

Refractory periods and climate forcing in cholera dynamics. Nature (2005) 3.98

Epidemic dynamics at the human-animal interface. Science (2009) 3.79

Cholera and climate: revisiting the quantitative evidence. Microbes Infect (2002) 3.61

Inapparent infections and cholera dynamics. Nature (2008) 3.53

ENSO and cholera: a nonstationary link related to climate change? Proc Natl Acad Sci U S A (2002) 3.45

Parasites dominate food web links. Proc Natl Acad Sci U S A (2006) 3.27

Is a healthy ecosystem one that is rich in parasites? Trends Ecol Evol (2006) 3.12

Parasites in food webs: the ultimate missing links. Ecol Lett (2008) 3.08

West Nile virus risk assessment and the bridge vector paradigm. Emerg Infect Dis (2005) 2.88

Ecology. Ecology for a crowded planet. Science (2004) 2.72

Ecosystem energetic implications of parasite and free-living biomass in three estuaries. Nature (2008) 2.53

Disentangling extrinsic from intrinsic factors in disease dynamics: a nonlinear time series approach with an application to cholera. Am Nat (2004) 2.52

Climate cycles and forecasts of cutaneous leishmaniasis, a nonstationary vector-borne disease. PLoS Med (2006) 2.34

Bolder thinking for conservation. Conserv Biol (2012) 2.32

A general model for food web structure. Science (2008) 2.32

Global migration dynamics underlie evolution and persistence of human influenza A (H3N2). PLoS Pathog (2010) 2.24

Estimation and inference of R0 of an infectious pathogen by a removal method. Math Biosci (2005) 2.09

Googling food webs: can an eigenvector measure species' importance for coextinctions? PLoS Comput Biol (2009) 2.03

Disease ecology, biodiversity, and the latitudinal gradient in income. PLoS Biol (2012) 2.00

A disease-mediated trophic cascade in the Serengeti and its implications for ecosystem C. PLoS Biol (2009) 2.00

Parasites affect food web structure primarily through increased diversity and complexity. PLoS Biol (2013) 1.99

Stochastic amplification in epidemics. J R Soc Interface (2007) 1.95

Agricultural intensification, priming for persistence and the emergence of Nipah virus: a lethal bat-borne zoonosis. J R Soc Interface (2011) 1.89

Skeletons, noise and population growth: the end of an old debate? Trends Ecol Evol (2004) 1.62

Phenotypic plasticity opposes species invasions by altering fitness surface. PLoS Biol (2006) 1.59

Frontiers in climate change-disease research. Trends Ecol Evol (2011) 1.55

Epidemic malaria and warmer temperatures in recent decades in an East African highland. Proc Biol Sci (2010) 1.52

Food web models: a plea for groups. Ecol Lett (2009) 1.52

Social exclusion modifies climate and deforestation impacts on a vector-borne disease. PLoS Negl Trop Dis (2008) 1.48

Forcing versus feedback: epidemic malaria and monsoon rains in northwest India. PLoS Comput Biol (2010) 1.46

Electronic referrals: what matters to the users. Stud Health Technol Inform (2012) 1.44

Comparing models for early warning systems of neglected tropical diseases. PLoS Negl Trop Dis (2007) 1.41

Sources and sinks: revisiting the criteria for identifying reservoirs for American cutaneous leishmaniasis. Trends Parasitol (2007) 1.40

Pathogen adaptation to seasonal forcing and climate change. Proc Biol Sci (2005) 1.40

Pathogen-induced reversal of native dominance in a grassland community. Proc Natl Acad Sci U S A (2007) 1.39

Spatial and temporal association of outbreaks of H5N1 influenza virus infection in wild birds with the 0 degrees C isotherm. PLoS Pathog (2010) 1.26

Highly localized sensitivity to climate forcing drives endemic cholera in a megacity. Proc Natl Acad Sci U S A (2012) 1.26

Canalization of the evolutionary trajectory of the human influenza virus. BMC Biol (2012) 1.26

Underestimating malaria risk under variable temperatures. Proc Natl Acad Sci U S A (2009) 1.24

The potential elimination of Plasmodium vivax malaria by relapse treatment: insights from a transmission model and surveillance data from NW India. PLoS Negl Trop Dis (2013) 1.24

Building epidemiological models from R0: an implicit treatment of transmission in networks. Proc Biol Sci (2007) 1.22

Impacts of climate change on public health in India: future research directions. Environ Health Perspect (2011) 1.18

Strength and tempo of selection revealed in viral gene genealogies. BMC Evol Biol (2011) 1.15

Serotype cycles in cholera dynamics. Proc Biol Sci (2006) 1.14

Malaria transmission pattern resilience to climatic variability is mediated by insecticide-treated nets. Malar J (2008) 1.14

Parallel patterns of increased virulence in a recently emerged wildlife pathogen. PLoS Biol (2013) 1.13

Attitudes towards health-care robots in a retirement village. Australas J Ageing (2011) 1.11

Linking community and disease ecology: the impact of biodiversity on pathogen transmission. Philos Trans R Soc Lond B Biol Sci (2012) 1.11

Uric acid is a mediator of the Plasmodium falciparum-induced inflammatory response. PLoS One (2009) 1.08

Spatial guilds in the Serengeti food web revealed by a Bayesian group model. PLoS Comput Biol (2011) 1.06

Functional links and robustness in food webs. Philos Trans R Soc Lond B Biol Sci (2009) 1.02

Spatial clustering in the spatio-temporal dynamics of endemic cholera. BMC Infect Dis (2010) 1.01

Metabolic approaches to understanding climate change impacts on seasonal host-macroparasite dynamics. Ecol Lett (2012) 1.01

Parasite invasion following host reintroduction: a case study of Yellowstone's wolves. Philos Trans R Soc Lond B Biol Sci (2012) 1.00

Highly pathogenic avian influenza virus (H5N1) infection in red foxes fed infected bird carcasses. Emerg Infect Dis (2008) 1.00

A stochastic model for ecological systems with strong nonlinear response to environmental drivers: application to two water-borne diseases. J R Soc Interface (2008) 1.00

Ecological theory to enhance infectious disease control and public health policy. Front Ecol Environ (2005) 0.99

Climate forcing and desert malaria: the effect of irrigation. Malar J (2011) 0.99

Plasmodium-induced inflammation by uric acid. PLoS Pathog (2008) 0.99

Spatio-temporal dynamics of pneumonia in bighorn sheep. J Anim Ecol (2013) 0.99

Parasite-mediated heterozygote advantage in an outbred songbird population. Biol Lett (2005) 0.98

Understanding shifts in wildfire regimes as emergent threshold phenomena. Am Nat (2011) 0.96

Robust scaling in ecosystems and the meltdown of patch size distributions before extinction. Ecol Lett (2010) 0.96

Random, top-down, or bottom-up coexistence of parasites: malaria population dynamics in multi-parasitic settings. Ecology (2009) 0.96

The roles of competition and mutation in shaping antigenic and genetic diversity in influenza. PLoS Pathog (2013) 0.95

Understanding the dynamics of rapidly evolving pathogens through modeling the tempo of antigenic change: influenza as a case study. Epidemics (2009) 0.94

Horizon scan of global conservation issues for 2011. Trends Ecol Evol (2010) 0.94

Epidemic enhancement in partially immune populations. PLoS One (2007) 0.93

Long-lasting transition toward sustainable elimination of desert malaria under irrigation development. Proc Natl Acad Sci U S A (2013) 0.91

A horizon scan of global conservation issues for 2012. Trends Ecol Evol (2011) 0.90

Linking influenza virus tissue tropism to population-level reproductive fitness. PLoS One (2012) 0.90

Transmission intensity and drug resistance in malaria population dynamics: implications for climate change. PLoS One (2010) 0.89

Global malaria maps and climate change: a focus on East African highlands. Trends Parasitol (2011) 0.89

Hyperinfectivity in cholera: a new mechanism for an old epidemiological model? PLoS Med (2006) 0.89

Evolution of pathogen virulence across space during an epidemic. Am Nat (2015) 0.88

Propensity of people with long-term conditions to use personal health records. Stud Health Technol Inform (2013) 0.87

Consequences of host heterogeneity, epitope immunodominance, and immune breadth for strain competition. J Theor Biol (2010) 0.84

Dynamics of the 'echo' effect in a phytoplankton system with nitrogen fixation. Bull Math Biol (2005) 0.83

Body-size scaling in an SEI model of wildlife diseases. Theor Popul Biol (2008) 0.82

Malaria control under unstable dynamics: reactive vs. climate-based strategies. Acta Trop (2013) 0.81

Homology blocks of Plasmodium falciparum var genes and clinically distinct forms of severe malaria in a local population. BMC Microbiol (2013) 0.81

Ecological factors driving the long-term evolution of influenza's host range. Proc Biol Sci (2010) 0.80

Flight behavior and performance of Rhodnius pallescens (Hemiptera: Reduviidae) on a tethered flight mill. J Med Entomol (2014) 0.79

Why a shared care record is an official medical record. N Z Med J (2013) 0.79

Evolution of virulence in heterogeneous host communities under multiple trade-offs. Evolution (2011) 0.79

Allometric scaling and seasonality in the epidemics of wildlife diseases. Am Nat (2008) 0.79

Seasonality in the migration and establishment of H3N2 Influenza lineages with epidemic growth and decline. BMC Evol Biol (2014) 0.79

Competitive coexistence in a dynamic landscape. Theor Popul Biol (2004) 0.78

The assembly, collapse and restoration of food webs. Philos Trans R Soc Lond B Biol Sci (2009) 0.78

Disease invasion: impacts on biodiversity and human health. Philos Trans R Soc Lond B Biol Sci (2012) 0.78

Gimme shelter--the relative sensitivity of parasitic nematodes with direct and indirect life cycles to climate change. Glob Chang Biol (2013) 0.78