Raffaella Giavazzi

Author PubWeight™ 51.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Shedding of the matrix metalloproteinases MMP-2, MMP-9, and MT1-MMP as membrane vesicle-associated components by endothelial cells. Am J Pathol 2002 2.27
2 Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: implications for ascites formation. Cancer Res 2003 2.14
3 Bioavailability of VEGF in tumor-shed vesicles depends on vesicle burst induced by acidic pH. Neoplasia 2006 1.98
4 Regulator of G-protein signaling 5 (RGS5) protein: a novel marker of cancer vasculature elicited and sustained by the tumor's proangiogenic microenvironment. Cell Mol Life Sci 2011 1.62
5 In vivo protein biotinylation for identification of organ-specific antigens accessible from the vasculature. Nat Methods 2005 1.32
6 E-3810 is a potent dual inhibitor of VEGFR and FGFR that exerts antitumor activity in multiple preclinical models. Cancer Res 2011 1.28
7 Antiangiogenic properties of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin: an orally bioavailable heat shock protein 90 modulator. Clin Cancer Res 2004 1.19
8 The adhesion molecule NCAM promotes ovarian cancer progression via FGFR signalling. EMBO Mol Med 2011 1.16
9 Antiangiogenic and antitumor activity of IDN 5390, a new taxane derivative. Clin Cancer Res 2002 1.09
10 An HSP90-mimic peptide revealed by fingerprinting the pool of antibodies from ovarian cancer patients. Oncogene 2004 1.07
11 Thrombospondin 1 as a scavenger for matrix-associated fibroblast growth factor 2. Blood 2003 1.07
12 Gene expression correlating with response to paclitaxel in ovarian carcinoma xenografts. Mol Cancer Ther 2004 1.05
13 Identification of novel vascular markers through gene expression profiling of tumor-derived endothelium. BMC Genomics 2008 1.03
14 Vascular endothelial growth factor stimulates organ-specific host matrix metalloproteinase-9 expression and ovarian cancer invasion. Mol Cancer Res 2008 0.99
15 Tumor delivery of chemotherapy combined with inhibitors of angiogenesis and vascular targeting agents. Front Oncol 2013 0.98
16 Circulating plasma vascular endothelial growth factor in mice bearing human ovarian carcinoma xenograft correlates with tumor progression and response to therapy. Mol Cancer Ther 2005 0.98
17 The combination of the tyrosine kinase receptor inhibitor SU6668 with paclitaxel affects ascites formation and tumor spread in ovarian carcinoma xenografts growing orthotopically. Clin Cancer Res 2003 0.96
18 Fibroblast growth factor-2 binding to the thrombospondin-1 type III repeats, a novel antiangiogenic domain. Int J Biochem Cell Biol 2007 0.95
19 Vascular-targeting activity of ZD6126, a novel tubulin-binding agent. Cancer Res 2003 0.95
20 Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors: an integrated strategy for the development of new antiangiogenic compounds. J Biol Chem 2010 0.94
21 The vascular targeting property of paclitaxel is enhanced by SU6668, a receptor tyrosine kinase inhibitor, causing apoptosis of endothelial cells and inhibition of angiogenesis. Clin Cancer Res 2006 0.93
22 The tyrosine kinase inhibitor E-3810 combined with paclitaxel inhibits the growth of advanced-stage triple-negative breast cancer xenografts. Mol Cancer Ther 2012 0.92
23 Anti-angiogenic, vascular-disrupting and anti-metastatic activities of vinflunine, the latest vinca alkaloid in clinical development. Eur J Cancer 2006 0.92
24 Comparative analysis of the membrane proteome of closely related metastatic and nonmetastatic tumor cells. Cancer Res 2009 0.92
25 A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6. EMBO Mol Med 2012 0.91
26 Vascular disrupting activity of tubulin-binding 1,5-diaryl-1H-imidazoles. J Med Chem 2009 0.90
27 Paclitaxel enhances therapeutic efficacy of the F8-IL2 immunocytokine to EDA-fibronectin-positive metastatic human melanoma xenografts. Cancer Res 2012 0.90
28 The effects of vandetanib on paclitaxel tumor distribution and antitumor activity in a xenograft model of human ovarian carcinoma. Neoplasia 2009 0.89
29 Determination of paclitaxel distribution in solid tumors by nano-particle assisted laser desorption ionization mass spectrometry imaging. PLoS One 2013 0.88
30 A proteomic approach for the identification of vascular markers of liver metastasis. Cancer Res 2009 0.87
31 Identification of a functional role for the protease-activated receptor-1 in hypoxic breast cancer cells. Eur J Cancer 2008 0.87
32 Potential antagonism of tubulin-binding anticancer agents in combination therapies. Clin Cancer Res 2005 0.85
33 A comparative analysis of oncofetal fibronectin and tenascin-C incorporation in tumour vessels using human recombinant SIP format antibodies. Histochem Cell Biol 2010 0.85
34 Antiangiogenic activity of trabectedin in myxoid liposarcoma: involvement of host TIMP-1 and TIMP-2 and tumor thrombospondin-1. Int J Cancer 2014 0.84
35 Metabolism of tumour-derived urokinase receptor and receptor fragments in cancer patients and xenografted mice. Thromb Haemost 2004 0.84
36 The immunocytokine F8-IL2 improves the therapeutic performance of sunitinib in a mouse model of renal cell carcinoma. J Urol 2010 0.84
37 Targeting angiogenesis with compounds from the extracellular matrix. Int J Biochem Cell Biol 2011 0.84
38 Chemotherapy counteracts metastatic dissemination induced by antiangiogenic treatment in mice. Mol Cancer Ther 2013 0.83
39 Interleukin-1β regulates the migratory potential of MDAMB231 breast cancer cells through the hypoxia-inducible factor-1α. Eur J Cancer 2010 0.82
40 Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies. Neoplasia 2012 0.82
41 Protease-activated receptor-1 (PAR-1) promotes the motility of human melanomas and is associated to their metastatic phenotype. Clin Exp Metastasis 2009 0.82
42 Solution state conformation and degradation of cyclopeptides containing an NGR motif. J Pept Sci 2005 0.80
43 Identification of thrombin-like activity in ovarian cancer associated ascites and modulation of multiple cytokine networks. Thromb Haemost 2011 0.80
44 Pharmacokinetics and antineoplastic activity of galectin-1-targeting OTX008 in combination with sunitinib. Cancer Chemother Pharmacol 2013 0.79
45 Thrombospondin-1 is part of a Slug-independent motility and metastatic program in cutaneous melanoma, in association with VEGFR-1 and FGF-2. Pigment Cell Melanoma Res 2014 0.79
46 Differential vascular expression and regulation of oncofetal tenascin-C and fibronectin variants in renal cell carcinoma (RCC): implications for an individualized angiogenesis-related targeted drug delivery. Histochem Cell Biol 2011 0.78
47 In vivo measurement of vascular modulation in experimental tumors using a fluorescent contrast agent. Photochem Photobiol 2008 0.78
48 Dual targeting of tumor and endothelial cells by gonadotropin-releasing hormone agonists to reduce melanoma angiogenesis. Endocrinology 2010 0.77
49 Impact of VEGF-dependent tumour micro-environment on EDB fibronectin expression by subcutaneous human tumour xenografts in nude mice. J Pathol 2009 0.77
50 Glycerophosphoinositols inhibit the ability of tumour cells to invade the extracellular matrix. Eur J Cancer 2005 0.76
51 IDN 5390: a new concept in taxane development. Anticancer Drugs 2003 0.76
52 Inactivating STAT3: bad for tumor, good for muscle. Cell Cycle 2015 0.75
53 Vascular endothelium summary statement III: Cancer prevention and control. Vascul Pharmacol 2006 0.75
54 Correction: Sunitinib prevents cachexia and prolongs survival of mice bearing renal cancer by restraining STAT3 and MuRF-1 activation in muscle. Oncotarget 2016 0.75