PubRank

Hideki Nishitoh

Author PubWeight™ 29.84‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity. Nat Immunol 2005 4.32
2 Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: advanced findings from ASK1 knockout mice. Antioxid Redox Signal 2002 1.59
3 Roles of MAPKKK ASK1 in stress-induced cell death. Cell Struct Funct 2003 1.58
4 A novel monoclonal antibody reveals a conformational alteration shared by amyotrophic lateral sclerosis-linked SOD1 mutants. Ann Neurol 2012 1.55
5 ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis. EMBO J 2009 1.46
6 Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation. EMBO Rep 2004 1.42
7 Survival and apoptosis signals in ER stress: the role of protein kinases. J Chem Neuroanat 2004 1.29
8 CHOP is a multifunctional transcription factor in the ER stress response. J Biochem 2011 1.20
9 Phosphorylation-dependent scaffolding role of JSAP1/JIP3 in the ASK1-JNK signaling pathway. A new mode of regulation of the MAP kinase cascade. J Biol Chem 2002 1.16
10 The cytoplasmic domain of Alzheimer's amyloid-beta protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via dimerization. J Pharmacol Exp Ther 2003 1.08
11 STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein. Mol Cell 2012 1.04
12 The expression of Fn14 via mechanical stress-activated JNK contributes to apoptosis induction in osteoblasts. J Biol Chem 2014 0.99
13 CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response. EMBO J 2010 0.99
14 Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis. Biochem J 2002 0.97
15 Apoptosis signaling kinases: from stress response to health outcomes. Antioxid Redox Signal 2011 0.96
16 ASK1 regulates influenza virus infection-induced apoptotic cell death. Biochem Biophys Res Commun 2003 0.90
17 Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates hydrogen peroxide-induced apoptosis in human pulmonary vascular endothelial cells. Crit Care Med 2003 0.90
18 USP14 inhibits ER-associated degradation via interaction with IRE1alpha. Biochem Biophys Res Commun 2009 0.89
19 Targeting ASK1 in ER stress-related neurodegenerative diseases. Expert Opin Ther Targets 2009 0.88
20 ASK3 responds to osmotic stress and regulates blood pressure by suppressing WNK1-SPAK/OSR1 signaling in the kidney. Nat Commun 2012 0.87
21 Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates nitric oxide-induced activator protein-1 activation in human bronchial epithelial cells. Am J Respir Crit Care Med 2003 0.87
22 SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency. Mol Cell 2013 0.86
23 Involvement of ASK1-p38 pathway in the pathogenesis of diabetes triggered by pancreatic ß cell exhaustion. Biochim Biophys Acta 2013 0.80
24 GCN5 protects vertebrate cells against UV-irradiation via controlling gene expression of DNA polymerase η. J Biol Chem 2012 0.76
25 GCN5 is essential for IRF-4 gene expression followed by transcriptional activation of Blimp-1 in immature B cells. J Leukoc Biol 2013 0.75
26 Histone acetyltransferase p300/CBP-associated factor is an effective suppressor of secretory immunoglobulin synthesis in immature B cells. Microbiol Immunol 2015 0.75