Published in PLoS One on December 19, 2012
Diabetes and retinal vascular dysfunction. J Ophthalmic Vis Res (2015) 0.98
Heparanase induced by advanced glycation end products (AGEs) promotes macrophage migration involving RAGE and PI3K/AKT pathway. Cardiovasc Diabetol (2013) 0.91
Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1. PLoS One (2013) 0.87
Altered transendothelial transport of hormones as a contributor to diabetes. Diabetes Metab J (2014) 0.78
Overexpression of uncoupling protein 2 inhibits the high glucose-induced apoptosis of human umbilical vein endothelial cells. Int J Mol Med (2016) 0.77
Lack of PGC-1α exacerbates high glucose-induced apoptosis in human umbilical vein endothelial cells through activation of VADC1. Int J Clin Exp Pathol (2015) 0.76
High glucose facilitated endothelial heparanase transfer to the cardiomyocyte modifies its cell death signature. Cardiovasc Res (2016) 0.75
LRP-1 Pathway Targeted Inhibition of Vascular Abnormalities in the Retina of Diabetic Mice. Curr Eye Res (2016) 0.75
Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders. N Engl J Med (1994) 16.24
Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake. J Biol Chem (2002) 6.01
The 14-year incidence of visual loss in a diabetic population. Ophthalmology (1998) 4.08
Cell-surface glycosaminoglycans. Annu Rev Biochem (1984) 3.68
Heparan sulfates of cultured cells. I. Membrane-associated and cell-sap species in Chinese hamster cells. Biochemistry (1971) 2.63
Regulation of tight junctions and loss of barrier function in pathophysiology. Int J Biochem Cell Biol (2004) 2.54
Activation of protein kinase C by elevation of glucose concentration: proposal for a mechanism in the development of diabetic vascular complications. Proc Natl Acad Sci U S A (1989) 2.45
Structure of the pericellular matrix: association of heparan and chondroitin sulfates with fibronectin-procollagen fibers. Cell (1982) 2.20
Vascular endothelial growth factor (VEGF)-induced retinal vascular permeability is mediated by intercellular adhesion molecule-1 (ICAM-1). Am J Pathol (2000) 2.03
Glucose and diabetic vascular disease. FASEB J (1992) 2.00
Cell-surface proteoglycans as molecular portals for cationic peptide and polymer entry into cells. Biochem Soc Trans (2007) 1.49
Mapping the blood vessels with paracellular permeability in the retinas of diabetic rats. Invest Ophthalmol Vis Sci (2003) 1.45
Subthreshold (retinal pigment epithelium) photocoagulation in macular diseases: a pilot study. Br J Ophthalmol (2000) 1.29
Heparanase is essential for the development of diabetic nephropathy in mice. Diabetes (2011) 1.29
Cellular uptake of mammalian heparanase precursor involves low density lipoprotein receptor-related proteins, mannose 6-phosphate receptors, and heparan sulfate proteoglycans. J Biol Chem (2005) 1.22
COG1410, a novel apolipoprotein E-based peptide, improves functional recovery in a murine model of traumatic brain injury. J Neurotrauma (2007) 1.20
The receptor-binding region of human apolipoprotein E has direct anti-infective activity. J Infect Dis (2005) 1.20
Pathophysiology of diabetic macular edema. Dev Ophthalmol (2007) 1.20
A monoclonal antibody against GBM heparan sulfate induces an acute selective proteinuria in rats. Kidney Int (1992) 1.19
Endothelial negative surface charge areas and blood-brain barrier function. Acta Physiol Scand (1985) 1.15
Distribution of GBM heparan sulfate proteoglycan core protein and side chains in human glomerular diseases. Kidney Int (1993) 1.07
Effective treatment of ocular HSK with a human apolipoprotein E mimetic peptide in a mouse eye model. Invest Ophthalmol Vis Sci (2008) 1.07
Heparanase levels are elevated in the urine and plasma of type 2 diabetes patients and associate with blood glucose levels. PLoS One (2011) 1.01
Cell surface binding and uptake of arginine- and lysine-rich penetratin peptides in absence and presence of proteoglycans. Biochim Biophys Acta (2012) 0.98
Apolipoprotein E binding to low density lipoprotein receptor-related protein-1 inhibits cell migration via activation of cAMP-dependent protein kinase A. J Biol Chem (2003) 0.97
Involvement of human heparanase in the pathogenesis of diabetic nephropathy. Isr Med Assoc J (2002) 0.96
A human apolipoprotein E mimetic peptide effectively inhibits HSV-1 TK-positive and TK-negative acute epithelial keratitis in rabbits. Curr Eye Res (2009) 0.86
Functional changes in vascular smooth muscle and endothelium of arteries during diabetes mellitus. Life Sci (1992) 0.86
A novel peptide derived from human apolipoprotein E is an inhibitor of tumor growth and ocular angiogenesis. PLoS One (2011) 0.86
Structure and function of proteoglycans of cartilage and cell-matrix interactions. Soc Gen Physiol Ser (1977) 0.84
Human-protein-derived peptides for intracellular delivery of biomolecules. Biochem J (2012) 0.78
HSV-1 DNA in tears and saliva of normal adults. Invest Ophthalmol Vis Sci (2005) 2.13
A role for 3-O-sulfated heparan sulfate in cell fusion induced by herpes simplex virus type 1. J Gen Virol (2004) 1.51
Role for 3-O-sulfated heparan sulfate as the receptor for herpes simplex virus type 1 entry into primary human corneal fibroblasts. J Virol (2006) 1.44
Ocular HSV-1 latency, reactivation and recurrent disease. Semin Ophthalmol (2008) 1.41
HSV-1 infection of human brain cells induces miRNA-146a and Alzheimer-type inflammatory signaling. Neuroreport (2009) 1.36
Characterization of heparan sulphate 3-O-sulphotransferase isoform 6 and its role in assisting the entry of herpes simplex virus type 1. Biochem J (2005) 1.31
microRNA (miRNA) speciation in Alzheimer's disease (AD) cerebrospinal fluid (CSF) and extracellular fluid (ECF). Int J Biochem Mol Biol (2012) 1.31
Histone deacetylase inhibitors induce reactivation of herpes simplex virus type 1 in a latency-associated transcript-independent manner in neuronal cells. J Neurovirol (2005) 1.27
Effect of immunosuppression on gene expression in the HSV-1 latently infected mouse trigeminal ganglion. Invest Ophthalmol Vis Sci (2002) 1.21
A role for herpesvirus entry mediator as the receptor for herpes simplex virus 1 entry into primary human trabecular meshwork cells. J Virol (2005) 1.21
The high prevalence of herpes simplex virus type 1 DNA in human trigeminal ganglia is not a function of age or gender. J Virol (2008) 1.19
Spreading of Alzheimer's disease inflammatory signaling through soluble micro-RNA. Neuroreport (2012) 1.18
Dipeptide monoester ganciclovir prodrugs for treating HSV-1-induced corneal epithelial and stromal keratitis: in vitro and in vivo evaluations. J Ocul Pharmacol Ther (2005) 1.17
Herpes simplex virus entry receptor nectin-1 is widely expressed in the murine eye. Curr Eye Res (2004) 1.15
During herpes simplex virus type 1 infection of rabbits, the ability to express the latency-associated transcript increases latent-phase transcription of lytic genes. J Virol (2008) 1.14
Regulation of TREM2 expression by an NF-кB-sensitive miRNA-34a. Neuroreport (2013) 1.13
Expression of inflammatory genes in the primary visual cortex of late-stage Alzheimer's disease. Neuroreport (2007) 1.12
Acyclovir or Aβ42 peptides attenuate HSV-1-induced miRNA-146a levels in human primary brain cells. Neuroreport (2010) 1.11
Engineered nanoparticles in cancer therapy. Recent Pat Drug Deliv Formul (2007) 1.11
Modulation of Mycobacterium tuberculosis DnaA protein-adenine-nucleotide interactions by acidic phospholipids. Biochem J (2002) 1.10
Rabbit and mouse models of HSV-1 latency, reactivation, and recurrent eye diseases. J Biomed Biotechnol (2012) 1.09
Up-regulation of NF-kB-sensitive miRNA-125b and miRNA-146a in metal sulfate-stressed human astroglial (HAG) primary cell cultures. J Inorg Biochem (2011) 1.08
Modeling the loading and unloading of drugs into nanotubes. Small (2009) 1.07
Effective treatment of ocular HSK with a human apolipoprotein E mimetic peptide in a mouse eye model. Invest Ophthalmol Vis Sci (2008) 1.07
Intracerebral propagation of Alzheimer's disease: strengthening evidence of a herpes simplex virus etiology. Alzheimers Dement (2012) 1.04
Receptor interacting protein kinase-mediated necrosis contributes to cone and rod photoreceptor degeneration in the retina lacking interphotoreceptor retinoid-binding protein. J Neurosci (2013) 1.02
The intrinsic ATPase activity of Mycobacterium tuberculosis DnaA promotes rapid oligomerization of DnaA on oriC. Mol Microbiol (2006) 1.01
Tryptophan-based peptides to synthesize gold and silver nanoparticles: a mechanistic and kinetic study. Chemistry (2007) 1.00
In vivo antiviral efficacy of a dipeptide acyclovir prodrug, val-val-acyclovir, against HSV-1 epithelial and stromal keratitis in the rabbit eye model. Invest Ophthalmol Vis Sci (2003) 1.00
Synchronous replication initiation in novel Mycobacterium tuberculosis dnaA cold-sensitive mutants. Mol Microbiol (2008) 0.99
Repressor element-1 silencing transcription factor/neuronal restrictive silencer factor (REST/NRSF) can regulate HSV-1 immediate-early transcription via histone modification. Virol J (2007) 0.99
Recent progress in ocular drug delivery for posterior segment disease: emphasis on transscleral iontophoresis. Adv Drug Deliv Rev (2005) 0.99
Inhibition of hepatitis C virus replication by intracellular delivery of multiple siRNAs by nanosomes. Mol Ther (2012) 0.98
Sodium butyrate: a chemical inducer of in vivo reactivation of herpes simplex virus type 1 in the ocular mouse model. J Virol (2007) 0.98
Ocular herpes simplex virus: how are latency, reactivation, recurrent disease and therapy interrelated? Future Microbiol (2011) 0.97
The region of the HSV-1 latency-associated transcript required for epinephrine-induced reactivation in the rabbit does not include the 2.0-kb intron. Virology (2002) 0.97
Lytic HSV-1 infection induces the multifunctional transcription factor Early Growth Response-1 (EGR-1) in rabbit corneal cells. Virol J (2011) 0.95
A double-blind placebo-controlled study to evaluate valacyclovir alone and with aspirin for asymptomatic HSV-1 DNA shedding in human tears and saliva. Invest Ophthalmol Vis Sci (2009) 0.94
Ocular herpes simplex virus type 1: is the cornea a reservoir for viral latency or a fast pit stop? Cornea (2011) 0.93
Obesity-associated dysregulation of calpastatin and MMP-15 in adipose-derived stromal cells results in their enhanced invasion. Stem Cells (2012) 0.93
Herpes simplex virus type 1 DNA in human corneas: what are the virological and clinical implications? J Infect Dis (2009) 0.92
Sustained-release ophthalmic drug delivery systems for treatment of macular disorders: present and future applications. Drugs Aging (2007) 0.90
Novel ascorbic acid based ionic liquids for the in situ synthesis of quasi-spherical and anisotropic gold nanostructures in aqueous medium. Chemistry (2008) 0.90
Regulation of herpes simplex virus type 1 thymidine kinase gene expression by thyroid hormone receptor in cultured neuronal cells. J Neurovirol (2010) 0.90
Microarray analysis of host gene expression for comparison between naïve and HSV-1 latent rabbit trigeminal ganglia. Mol Vis (2008) 0.89
Ascorbate-assisted growth of hierarchical ZnO nanostructures: sphere, spindle, and flower and their catalytic properties. Langmuir (2010) 0.89
Development and optimization of nanosomal formulations for siRNA delivery to the liver. Eur J Pharm Biopharm (2011) 0.89
Expression of nectin-1 in normal and herpes simplex virus type 1-infected murine brain. Appl Immunohistochem Mol Morphol (2006) 0.89
An unusual soluble beta-turn-rich conformation of prion is involved in fibril formation and toxic to neuronal cells. Biochem Biophys Res Commun (2005) 0.89
Effect of human apolipoprotein E genotype on the pathogenesis of experimental ocular HSV-1. Exp Eye Res (2008) 0.88
Wnt6 expression in epidermis and epithelial tissues during Xenopus organogenesis. Dev Dyn (2008) 0.87
Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase. J Neurosci (2013) 0.87
Beta-Amyloid Precursor Protein (βAPP) Processing in Alzheimer's Disease (AD) and Age-Related Macular Degeneration (AMD). Mol Neurobiol (2014) 0.87
A human apolipoprotein E mimetic peptide effectively inhibits HSV-1 TK-positive and TK-negative acute epithelial keratitis in rabbits. Curr Eye Res (2009) 0.86
A novel peptide derived from human apolipoprotein E is an inhibitor of tumor growth and ocular angiogenesis. PLoS One (2011) 0.86
Drug delivery to the posterior segment of the eye for pharmacologic therapy. Expert Rev Ophthalmol (2010) 0.85
Kaposi's sarcoma associated herpesvirus G-protein coupled receptor activation of cyclooxygenase-2 in vascular endothelial cells. Virol J (2007) 0.84
Effect of different ratios of high and low molecular weight PLGA blend on the characteristics of pentamidine microcapsules. Int J Pharm (2004) 0.84
Clinical and antiviral efficacy of an ophthalmic formulation of dexamethasone povidone-iodine in a rabbit model of adenoviral keratoconjunctivitis. Invest Ophthalmol Vis Sci (2011) 0.84
Preparation and in-vitro/in-vivo evaluation of surface-modified poly (lactide-co-glycolide) fluorescent nanoparticles. J Pharm Pharmacol (2010) 0.83
Correlation between catalytic activity and surface ligands of monolayer protected gold nanoparticles. J Colloid Interface Sci (2011) 0.83
Effect of acyclovir on thermal stress-induced herpesvirus reactivation. Curr Eye Res (2004) 0.83
Stability of lyophilized siRNA nanosome formulations. Int J Pharm (2011) 0.83
Global Health Technology 2.0. IEEE Pulse (2011) 0.83
Herpesvirus infection of ICAM-1-deficient mice. Curr Eye Res (2004) 0.83
Selective accumulation of aluminum in cerebral arteries in Alzheimer's disease (AD). J Inorg Biochem (2013) 0.83
Cellular delivery of PEGylated PLGA nanoparticles. J Pharm Pharmacol (2011) 0.83
Development of nanosomes using high-pressure homogenization for gene therapy. J Pharm Pharmacol (2010) 0.83
Nanoparticle melting as a stefan moving boundary problem. J Nanosci Nanotechnol (2009) 0.83
HSV-1 latent rabbits shed viral DNA into their saliva. Virol J (2012) 0.82
Hepatitis E antibodies in laboratory rabbits from 2 US vendors. Emerg Infect Dis (2014) 0.82
4-1BB-like molecule is expressed in islet-infiltrating mononuclear cells and in the gray matter of the brain. Cell Biol Int (2002) 0.82
Effect of high versus low oral doses of valacyclovir on herpes simplex virus-1 DNA shedding into tears of latently infected rabbits. Invest Ophthalmol Vis Sci (2010) 0.81
pH-controlled reversible assembly of peptide-functionalized gold nanoparticles. Langmuir (2007) 0.81
Alternate delivery route for amifostine as a radio-/chemo-protecting agent. J Pharm Pharmacol (2008) 0.81
Preparation of polylactide-co-glycolide and chitosan hybrid microcapsules of amifostine using coaxial ultrasonic atomizer with solvent evaporation. J Pharm Pharmacol (2008) 0.81