Published in PLoS One on December 21, 2012
Resveratrol protects C6 astrocyte cell line against hydrogen peroxide-induced oxidative stress through heme oxygenase 1. PLoS One (2013) 1.02
Characterization of adult rat astrocyte cultures. PLoS One (2013) 0.92
Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous system. Pharmacol Rev (2014) 0.87
Proteome changes in the small intestinal mucosa of broilers (Gallus gallus) induced by high concentrations of atmospheric ammonia. Proteome Sci (2015) 0.82
High Concentrations of Atmospheric Ammonia Induce Alterations in the Hepatic Proteome of Broilers (Gallus gallus): An iTRAQ-Based Quantitative Proteomic Analysis. PLoS One (2015) 0.82
Gliopreventive effects of guanosine against glucose deprivation in vitro. Purinergic Signal (2013) 0.81
Morphological changes of cortical pyramidal neurons in hepatic encephalopathy. BMC Neurosci (2014) 0.81
Optical and SPION-enhanced MR imaging shows that trans-stilbene inhibitors of NF-κB concomitantly lower Alzheimer's disease plaque formation and microglial activation in AβPP/PS-1 transgenic mouse brain. J Alzheimers Dis (2014) 0.81
Signal transduction in inherited metabolic disorders: a model for a possible pathogenetic mechanism. J Inherit Metab Dis (2015) 0.76
Hepatic injury is associated with cell cycle arrest and apoptosis with alteration of cyclin A and D1 in ammonium chloride-induced hyperammonemic rats. Exp Ther Med (2015) 0.75
A(a)LS: Ammonia-induced amyotrophic lateral sclerosis. F1000Res (2015) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov (2006) 11.77
Differentiated rat glial cell strain in tissue culture. Science (1968) 6.49
Astrocytes are active players in cerebral innate immunity. Trends Immunol (2007) 4.08
Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation. Cell Metab (2011) 3.57
When NRF2 talks, who's listening? Antioxid Redox Signal (2010) 2.32
Astrocyte-neuron metabolic relationships: for better and for worse. Trends Neurosci (2011) 2.24
A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis. Brain Res Brain Res Rev (2004) 2.14
The glutamate-glutamine cycle is not stoichiometric: fates of glutamate in brain. J Neurosci Res (2007) 2.02
Glutathione pathways in the brain. Biol Chem (2003) 2.01
TNF receptor superfamily-induced cell death: redox-dependent execution. FASEB J (2006) 1.98
S100B's double life: intracellular regulator and extracellular signal. Biochim Biophys Acta (2008) 1.97
S100B in brain damage and neurodegeneration. Microsc Res Tech (2003) 1.85
Neurobiology of ammonia. Prog Neurobiol (2002) 1.84
Resveratrol protects against experimental stroke: putative neuroprotective role of heme oxygenase 1. Exp Neurol (2010) 1.78
Antioxidants: Molecules, medicines, and myths. Biochem Biophys Res Commun (2010) 1.74
What is new for an old molecule? Systematic review and recommendations on the use of resveratrol. PLoS One (2011) 1.74
Astrocytic control of glutamatergic activity: astrocytes as stars of the show. Trends Neurosci (2004) 1.69
Glutamine and its relationship with intracellular redox status, oxidative stress and cell proliferation/death. Int J Biochem Cell Biol (2002) 1.55
TNFα controls glutamatergic gliotransmission in the hippocampal dentate gyrus. Neuron (2011) 1.54
NF-κB is 25. Nat Immunol (2011) 1.50
The Janus face of glial-derived S100B: beneficial and detrimental functions in the brain. Restor Neurol Neurosci (2003) 1.49
Hepatic encephalopathy: a central neuroinflammatory disorder? Hepatology (2011) 1.27
Oxidative stress and mitogen-activated protein kinase phosphorylation mediate ammonia-induced cell swelling and glutamate uptake inhibition in cultured astrocytes. J Neurosci (2006) 1.24
Signaling factors in the mechanism of ammonia neurotoxicity. Metab Brain Dis (2008) 1.20
Hepatic encephalopathy: molecular mechanisms underlying the clinical syndrome. J Neurol Sci (1999) 1.19
Glial cells more than support cells? Int J Biochem Cell Biol (2006) 1.18
Resveratrol: preventing properties against vascular alterations and ageing. Mol Nutr Food Res (2005) 1.17
S100 beta stimulates inducible nitric oxide synthase activity and mRNA levels in rat cortical astrocytes. J Biol Chem (1996) 1.15
Resveratrol protects rats from Aβ-induced neurotoxicity by the reduction of iNOS expression and lipid peroxidation. PLoS One (2011) 1.15
Cyclic AMP: a selective modulator of NF-κB action. Cell Mol Life Sci (2011) 1.14
Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death. Free Radic Biol Med (2010) 1.13
Mechanisms of tumor necrosis factor-alpha-induced interleukin-6 synthesis in glioma cells. J Neuroinflammation (2010) 1.09
Hepatic encephalopathy, ammonia, glutamate, glutamine and oxidative stress. Ann Hepatol (2009) 1.08
Interaction of oxidative stress, astrocyte swelling and cerebral ammonia toxicity. Curr Opin Clin Nutr Metab Care (2010) 1.03
Intracellular Ca2+ and Zn2+ levels regulate the alternative cell density-dependent secretion of S100B in human glioblastoma cells. J Biol Chem (2001) 1.02
Metabolic trafficking between neurons and astrocytes: the glutamate/glutamine cycle revisited. Dev Neurosci (1995) 1.02
MAPKs are key players in mediating cytokine release and cell death induced by unconjugated bilirubin in cultured rat cortical astrocytes. Eur J Neurosci (2007) 1.01
Superoxide production and antioxidant enzymes in ammonia intoxication in rats. Free Radic Res (1997) 1.01
The rate of NF-κB nuclear translocation is regulated by PKA and A kinase interacting protein 1. PLoS One (2011) 0.99
Anti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease. Ann N Y Acad Sci (2011) 0.98
The role of astrocytes in the physiology and pathology of the central nervous system. Acta Neurobiol Exp (Wars) (2006) 0.97
Nuclear factor erythroid 2-related factor 2 facilitates neuronal glutathione synthesis by upregulating neuronal excitatory amino acid transporter 3 expression. J Neurosci (2011) 0.95
Resveratrol prevents alcohol-induced cognitive deficits and brain damage by blocking inflammatory signaling and cell death cascade in neonatal rat brain. J Neurochem (2011) 0.94
Haloperidol and clozapine decrease S100B release from glial cells. Neuroscience (2010) 0.93
Ammonia induces RNA oxidation in cultured astrocytes and brain in vivo. Hepatology (2008) 0.92
Acute insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes, an effect of pH. J Biol Chem (2005) 0.92
Protective effects of resveratrol on hydrogen peroxide induced toxicity in primary cortical astrocyte cultures. Neurochem Res (2007) 0.92
Glutamine in the mechanism of ammonia-induced astrocyte swelling. Neurochem Int (2006) 0.92
Resveratrol modulates astroglial functions: neuroprotective hypothesis. Ann N Y Acad Sci (2011) 0.91
Neuroinflammation in acute liver failure: mechanisms and novel therapeutic targets. Neurochem Int (2011) 0.91
Lipopolysaccharide modulates astrocytic S100B secretion: a study in cerebrospinal fluid and astrocyte cultures from rats. J Neuroinflammation (2011) 0.90
Resveratrol increases glutamate uptake, glutathione content, and S100B secretion in cortical astrocyte cultures. Cell Mol Neurobiol (2007) 0.89
Resveratrol increases glutamate uptake and glutamine synthetase activity in C6 glioma cells. Arch Biochem Biophys (2006) 0.89
Oxidative and nitrosative stress in ammonia neurotoxicity. Hepatology (2003) 0.88
Melatonin synergistically increases resveratrol-induced heme oxygenase-1 expression through the inhibition of ubiquitin-dependent proteasome pathway: a possible role in neuroprotection. J Pineal Res (2010) 0.87
Morphological alterations and induction of oxidative stress in glial cells caused by the branched-chain alpha-keto acids accumulating in maple syrup urine disease. Neurochem Int (2006) 0.87
A simple, sensitive and widely applicable ELISA for S100B: Methodological features of the measurement of this glial protein. J Neurosci Methods (2007) 0.87
Limited capacity for ammonia removal by brain in chronic liver failure: potential role of nitric oxide. Metab Brain Dis (2005) 0.87
Molecular mechanism of acute ammonia toxicity: role of NMDA receptors. Neurochem Int (2002) 0.87
Role of neuron-glia interaction in the regulation of brain glucose utilization. Diabetes Nutr Metab (2002) 0.87
Effect of the branched-chain alpha-keto acids accumulating in maple syrup urine disease on S100B release from glial cells. J Neurol Sci (2007) 0.84
Gap junction inhibitors modulate S100B secretion in astrocyte cultures and acute hippocampal slices. J Neurosci Res (2009) 0.84
Heme oxygenase 1: another possible target to explain the neuroprotective action of resveratrol, a multifaceted nutrient-based molecule. Exp Neurol (2010) 0.84
Glial pathology is modified by age in mood disorders--a systematic meta-analysis of serum S100B in vivo studies. J Affect Disord (2010) 0.84
The janus face of resveratrol in astroglial cells. Neurotox Res (2009) 0.84
Midazolam suppresses interleukin-1β-induced interleukin-6 release from rat glial cells. J Neuroinflammation (2011) 0.83
Effects of hyperammonemia and liver failure on glutamatergic neurotransmission. Metab Brain Dis (2002) 0.83
Resveratrol protects against oxidative injury induced by H2O2 in acute hippocampal slice preparations from Wistar rats. Arch Biochem Biophys (2008) 0.83
RNA oxidation and zinc in hepatic encephalopathy and hyperammonemia. Metab Brain Dis (2009) 0.82
cAMP mediates ammonia-induced programmed cell death in the microglial cell line BV-2. Eur J Neurosci (2007) 0.82
Resveratrol reduces glutamate-mediated monocyte chemotactic protein-1 expression via inhibition of extracellular signal-regulated kinase 1/2 pathway in rat hippocampal slice cultures. J Neurochem (2009) 0.81
Effects of acute hyperammonemia in vivo on oxidative metabolism in nonsynaptic rat brain mitochondria. Metab Brain Dis (1997) 0.81
Elevated serum levels of astroglial S100beta in patients with liver cirrhosis indicate early and subclinical portal-systemic encephalopathy. Metab Brain Dis (1999) 0.81
Resveratrol attenuates oxidative-induced DNA damage in C6 Glioma cells. Neurotoxicology (2007) 0.81
Responses in primary astrocytes and C6-glioma cells to ammonium chloride and dibutyryl cyclic-AMP. Neurochem Res (2000) 0.81
TGF beta 1 and TNF alpha potentiate nitric oxide production in astrocyte cultures by recruiting distinct subpopulations of cells to express NOS-2. Neurochem Int (2007) 0.80
S100B content and secretion decrease in astrocytes cultured in high-glucose medium. Neurochem Int (2007) 0.80
Actions of redox-active compound resveratrol under hydrogen peroxide insult in C6 astroglial cells. Toxicol In Vitro (2009) 0.79
Delayed induction of apoptosis by ammonia in C6 glioma cells. Neurochem Int (2000) 0.79
Neurotoxicity of ammonia and glutamate: molecular mechanisms and prevention. Neurotoxicology (1998) 0.79
Ammonia-induced alteration in S100B secretion in astrocytes is not reverted by creatine addition. Brain Res Bull (2006) 0.78
High glutamate decreases S100B secretion stimulated by serum deprivation in astrocytes. Neuroreport (2002) 0.78
Ammonium-induced calcium mobilization in 1321N1 astrocytoma cells. Toxicol Appl Pharmacol (2007) 0.78
Induction of S100B secretion in C6 astroglial cells by the major metabolites accumulating in glutaric acidemia type I. Metab Brain Dis (2010) 0.78
Effect of ammonia on cyclic AMP production in primary astrocyte cultures. Brain Res (1986) 0.77
The role of protein kinase C and cyclic AMP in the ammonia-induced shift of the taurine uptake/efflux balance towards efflux in C6 cells. Neurochem Res (2005) 0.76
What is new for an old molecule? Systematic review and recommendations on the use of resveratrol. PLoS One (2011) 1.74
Biological and methodological features of the measurement of S100B, a putative marker of brain injury. Clin Biochem (2008) 1.56
Expression and functional analysis of Na(+)-dependent glutamate transporters from zebrafish brain. Brain Res Bull (2009) 1.47
Riluzole enhances glutamate uptake in rat astrocyte cultures. Cell Mol Neurobiol (2004) 1.43
Neuron-specific enolase, S100B, and glial fibrillary acidic protein levels as outcome predictors in patients with severe traumatic brain injury. Neurosurgery (2011) 1.28
Serum S100B and antioxidant enzymes in bipolar patients. J Psychiatr Res (2006) 1.17
Resveratrol protects C6 astrocyte cell line against hydrogen peroxide-induced oxidative stress through heme oxygenase 1. PLoS One (2013) 1.02
Ketogenic diet increases glutathione peroxidase activity in rat hippocampus. Neurochem Res (2003) 1.00
Secretion of S100B, an astrocyte-derived neurotrophic protein, is stimulated by fluoxetine via a mechanism independent of serotonin. Prog Neuropsychopharmacol Biol Psychiatry (2008) 0.95
Serum S100B protein is increased in fasting rats. Arch Med Res (2006) 0.94
Adipocytes as an Important Source of Serum S100B and Possible Roles of This Protein in Adipose Tissue. Cardiovasc Psychiatry Neurol (2010) 0.93
S100B secretion is stimulated by IL-1beta in glial cultures and hippocampal slices of rats: Likely involvement of MAPK pathway. J Neuroimmunol (2008) 0.93
Nociception and locomotor activity are increased in ketogenic diet fed rats. Physiol Behav (2005) 0.92
Protective effects of resveratrol on hydrogen peroxide induced toxicity in primary cortical astrocyte cultures. Neurochem Res (2007) 0.92
Characterization of adult rat astrocyte cultures. PLoS One (2013) 0.92
Animal model of autism induced by prenatal exposure to valproate: altered glutamate metabolism in the hippocampus. Brain Res (2012) 0.91
Resveratrol modulates astroglial functions: neuroprotective hypothesis. Ann N Y Acad Sci (2011) 0.91
Lipopolysaccharide modulates astrocytic S100B secretion: a study in cerebrospinal fluid and astrocyte cultures from rats. J Neuroinflammation (2011) 0.90
Animal model of autism induced by prenatal exposure to valproate: behavioral changes and liver parameters. Brain Res (2011) 0.89
Astroglial and cognitive effects of chronic cerebral hypoperfusion in the rat. Brain Res (2008) 0.89
Resveratrol increases glutamate uptake, glutathione content, and S100B secretion in cortical astrocyte cultures. Cell Mol Neurobiol (2007) 0.89
Resveratrol increases glutamate uptake and glutamine synthetase activity in C6 glioma cells. Arch Biochem Biophys (2006) 0.89
Effects of chronic guanosine treatment on hippocampal damage and cognitive impairment of rats submitted to chronic cerebral hypoperfusion. Neurol Sci (2011) 0.88
Dietary omega-3 fatty acids attenuate cellular damage after a hippocampal ischemic insult in adult rats. J Nutr Biochem (2009) 0.88
Brain-derived neurotrophic factor in post-partum depressive mothers. Neurochem Res (2011) 0.88
Morphological alterations and induction of oxidative stress in glial cells caused by the branched-chain alpha-keto acids accumulating in maple syrup urine disease. Neurochem Int (2006) 0.87
Increased serum glial cell line-derived neurotrophic factor immunocontent during manic and depressive episodes in individuals with bipolar disorder. Neurosci Lett (2006) 0.87
Treadmill exercise induces hippocampal astroglial alterations in rats. Neural Plast (2013) 0.87
A simple, sensitive and widely applicable ELISA for S100B: Methodological features of the measurement of this glial protein. J Neurosci Methods (2007) 0.87
Huperzine A, but not tacrine, stimulates S100B secretion in astrocyte cultures. Life Sci (2013) 0.86
S100B and NSE serum levels in obstructive sleep apnea syndrome. Sleep Med (2006) 0.86
Chronically administered guanosine is anticonvulsant, amnesic and anxiolytic in mice. Brain Res (2003) 0.85
Glutamate uptake is stimulated by extracellular S100B in hippocampal astrocytes. Cell Mol Neurobiol (2006) 0.85
Effects of physical exercise on spatial memory and astroglial alterations in the hippocampus of diabetic rats. Metab Brain Dis (2011) 0.85
Gap junction inhibitors modulate S100B secretion in astrocyte cultures and acute hippocampal slices. J Neurosci Res (2009) 0.84
Guanosine enhances glutamate uptake in brain cortical slices at normal and excitotoxic conditions. Cell Mol Neurobiol (2002) 0.84
Effects of depressive-like behavior of rats on brain glutamate uptake. Neurochem Res (2010) 0.84
Effects of atypical (risperidone) and typical (haloperidol) antipsychotic agents on astroglial functions. Eur Arch Psychiatry Clin Neurosci (2009) 0.84
Influence of environmental enrichment on an object recognition task in CF1 mice. Physiol Behav (2010) 0.84
Long-term cyclosporine treatment: evaluation of serum biochemical parameters and histopathological alterations in Wistar rats. Exp Toxicol Pathol (2009) 0.84
Developmental changes in content of glial marker proteins in rats exposed to protein malnutrition. Brain Res (2007) 0.84
Mesenchymal stem cell adherence on poly(D, L-lactide-co-glycolide) nanofibers scaffold is integrin-beta 1 receptor dependent. J Biomed Nanotechnol (2012) 0.84
Interleukin-6-induced S100B secretion is inhibited by haloperidol and risperidone. Prog Neuropsychopharmacol Biol Psychiatry (2012) 0.84
The janus face of resveratrol in astroglial cells. Neurotox Res (2009) 0.84
Muscle injury: review of experimental models. J Electromyogr Kinesiol (2013) 0.83
The beneficial effects of treadmill step training on activity-dependent synaptic and cellular plasticity markers after complete spinal cord injury. Neurochem Res (2011) 0.83
Green tea (-)epigallocatechin-3-gallate reverses oxidative stress and reduces acetylcholinesterase activity in a streptozotocin-induced model of dementia. Behav Brain Res (2012) 0.83
Resveratrol protects against oxidative injury induced by H2O2 in acute hippocampal slice preparations from Wistar rats. Arch Biochem Biophys (2008) 0.83
RC-3095, a bombesin/gastrin-releasing peptide receptor antagonist, impairs aversive but not recognition memory in rats. Eur J Pharmacol (2004) 0.83
Moderate exercise training and chronic caloric restriction modulate redox status in rat hippocampus. Brain Res (2011) 0.83
Indole alkaloids of Psychotria as multifunctional cholinesterases and monoamine oxidases inhibitors. Phytochemistry (2012) 0.82
S100B-mediated inhibition of the phosphorylation of GFAP is prevented by TRTK-12. Neurochem Res (2004) 0.82
Differential effects of insulin on peripheral diabetes-related changes in mitochondrial bioenergetics: involvement of advanced glycosylated end products. Biochim Biophys Acta (2011) 0.82
Developmental changes in S100B content in brain tissue, cerebrospinal fluid, and astrocyte cultures of rats. Cell Mol Neurobiol (2002) 0.82
Hippocampal alterations in rats submitted to streptozotocin-induced dementia model are prevented by aminoguanidine. J Alzheimers Dis (2009) 0.82
Immunoassay for glial fibrillary acidic protein: antigen recognition is affected by its phosphorylation state. J Neurosci Methods (2007) 0.82
S100B secretion in acute brain slices: modulation by extracellular levels of Ca(2+) and K (+). Neurochem Res (2009) 0.82
Oral administration of guanosine impairs inhibitory avoidance performance in rats and mice. Neurobiol Learn Mem (2004) 0.81
Gliopreventive effects of guanosine against glucose deprivation in vitro. Purinergic Signal (2013) 0.81
Protective effects of guanosine against sepsis-induced damage in rat brain and cognitive impairment. Brain Behav Immun (2012) 0.81
Alterations of PI3K and Akt signaling pathways in the hippocampus and hypothalamus of Wistar rats treated with highly palatable food. Nutr Neurosci (2012) 0.81
Neuroglial alterations in rats submitted to the okadaic acid-induced model of dementia. Behav Brain Res (2011) 0.81