Cytokine expression profile of dengue patients at different phases of illness.

PubWeight™: 1.28‹?› | Rank: Top 10%

🔗 View Article (PMC 3527385)

Published in PLoS One on December 20, 2012

Authors

Anusyah Rathakrishnan1, Seok Mui Wang, Yongli Hu, Asif M Khan, Sasheela Ponnampalavanar, Lucy Chai See Lum, Rishya Manikam, Shamala Devi Sekaran

Author Affiliations

1: Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Articles citing this

Asymptomatic humans transmit dengue virus to mosquitoes. Proc Natl Acad Sci U S A (2015) 1.39

Cytokine kinetics of Zika virus-infected patients from acute to reconvalescent phase. Med Microbiol Immunol (2015) 1.01

Serum IL-10 as a marker of severe dengue infection. BMC Infect Dis (2013) 1.00

Platelet activation and apoptosis modulate monocyte inflammatory responses in dengue. J Immunol (2014) 0.98

Zika viral dynamics and shedding in rhesus and cynomolgus macaques. Nat Med (2016) 0.95

Predicting outcome from dengue. BMC Med (2014) 0.95

Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection. MBio (2015) 0.91

Slow resolution of inflammation in severe adult dengue patients. BMC Infect Dis (2016) 0.90

Control of acute dengue virus infection by natural killer cells. Front Immunol (2014) 0.86

Sphingosine 1-phosphate in acute dengue infection. PLoS One (2014) 0.84

Platelet activating factor contributes to vascular leak in acute dengue infection. PLoS Negl Trop Dis (2015) 0.84

Minimal within-host dengue models highlight the specific roles of the immune response in primary and secondary dengue infections. J R Soc Interface (2015) 0.82

Clinical and immunological markers of dengue progression in a study cohort from a hyperendemic area in Malaysia. PLoS One (2014) 0.81

Potential Harm of Prophylactic Platelet Transfusion in Adult Dengue Patients. PLoS Negl Trop Dis (2016) 0.80

Human platelets and their capacity of binding viruses: meaning and challenges? BMC Immunol (2015) 0.79

Utility of humanized BLT mice for analysis of dengue virus infection and antiviral drug testing. J Virol (2013) 0.78

Primary dengue virus infections induce differential cytokine production in Mexican patients. Mem Inst Oswaldo Cruz (2016) 0.77

Lack of clinical manifestations in asymptomatic dengue infection is attributed to broad down-regulation and selective up-regulation of host defence response genes. PLoS One (2014) 0.77

Differential proteomic analysis of virus-enriched fractions obtained from plasma pools of patients with dengue fever or severe dengue. BMC Infect Dis (2015) 0.76

Discovery and characterization of potential prognostic biomarkers for dengue hemorrhagic fever. Am J Trop Med Hyg (2014) 0.76

Spectrum of disease outcomes in mice infected with YFV-17D. J Gen Virol (2015) 0.75

Cytokine Profile of Children Hospitalized with Virologically-Confirmed Dengue during Two Phase III Vaccine Efficacy Trials. PLoS Negl Trop Dis (2016) 0.75

Normal free interleukin-18 (IL-18) plasma levels in dengue virus infection and the need to measure both total IL-18 and IL-18 binding protein levels. Clin Vaccine Immunol (2015) 0.75

Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model. PLoS One (2015) 0.75

Aspects of T Cell-Mediated Immunity Induced in Mice by a DNA Vaccine Based on the Dengue-NS1 Antigen after Challenge by the Intracerebral Route. PLoS One (2016) 0.75

Primary dengue haemorrhagic fever in patients from northeast of Brazil is associated with high levels of interferon-β during acute phase. Mem Inst Oswaldo Cruz (2016) 0.75

Post-dengue acute disseminated encephalomyelitis: A case report and meta-analysis. PLoS Negl Trop Dis (2017) 0.75

Dengue Virus Induces NK Cell Activation through TRAIL Expression during Infection. Mediators Inflamm (2017) 0.75

Meta-analysis of biomarkers for severe dengue infections. PeerJ (2017) 0.75

Articles cited by this

Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses. Am J Trop Med Hyg (1958) 40.44

Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nat Med (2003) 6.25

Control of homeostasis of CD8+ memory T cells by opposing cytokines. Science (2000) 6.22

Endothelial cells and VEGF in vascular development. Nature (2005) 4.92

Observations related to pathogenesis of dengue hemorrhagic fever. IV. Relation of disease severity to antibody response and virus recovered. Yale J Biol Med (1970) 4.30

Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1. Nature (2000) 3.81

Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature (1993) 3.67

Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2. Nat Med (2003) 3.16

Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo. J Exp Med (1995) 2.99

Interleukin 1 receptor antagonist (IL-1Ra) is an acute-phase protein. J Clin Invest (1997) 2.56

Progress towards a dengue vaccine. Lancet Infect Dis (2009) 2.45

Activation of T lymphocytes in dengue virus infections. High levels of soluble interleukin 2 receptor, soluble CD4, soluble CD8, interleukin 2, and interferon-gamma in sera of children with dengue. J Clin Invest (1991) 2.37

Immunity and immunopathology in dengue virus infections. Semin Immunol (1992) 2.32

Interleukin-18. Methods (1999) 2.30

IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12. J Immunol (1997) 2.29

Monocyte chemotactic protein 3 is a most effective basophil- and eosinophil-activating chemokine. J Exp Med (1994) 2.29

CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection. Nat Med (2005) 2.23

Understanding the contribution of cellular immunity to dengue disease pathogenesis. Immunol Rev (2008) 2.19

Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity. BMC Infect Dis (2008) 2.08

Platelet chemokines and chemokine receptors: linking hemostasis, inflammation, and host defense. Microcirculation (2003) 1.94

Cytokine cascade in dengue hemorrhagic fever: implications for pathogenesis. FEMS Immunol Med Microbiol (2000) 1.88

Detection of specific IgM in dengue infection. Southeast Asian J Trop Med Public Health (1987) 1.85

Circulating levels of tumour necrosis factor-alpha & interferon-gamma in patients with dengue & dengue haemorrhagic fever during an outbreak. Indian J Med Res (2006) 1.83

Elevated plasma interleukin-10 levels in acute dengue correlate with disease severity. J Med Virol (1999) 1.79

IL8 release, tight junction and cytoskeleton dynamic reorganization conducive to permeability increase are induced by dengue virus infection of microvascular endothelial monolayers. J Gen Virol (2004) 1.77

Both CXCR3 and CXCL10/IFN-inducible protein 10 are required for resistance to primary infection by dengue virus. J Immunol (2006) 1.70

Kinetics of dengue virus-specific serum immunoglobulin classes and subclasses correlate with clinical outcome of infection. J Clin Microbiol (2001) 1.70

Enhancement of dengue virus infection in monocytes by flavivirus antisera. Am J Trop Med Hyg (1980) 1.65

MCP-1, a highly expressed chemokine in dengue haemorrhagic fever/dengue shock syndrome patients, may cause permeability change, possibly through reduced tight junctions of vascular endothelium cells. J Gen Virol (2006) 1.63

Correlation of serum levels of macrophage migration inhibitory factor with disease severity and clinical outcome in dengue patients. Am J Trop Med Hyg (2006) 1.61

IL-10 levels in Dengue patients: some findings from the exceptional epidemiological conditions in Cuba. J Med Virol (2004) 1.50

Activation of endothelial cells via antibody-enhanced dengue virus infection of peripheral blood monocytes. J Virol (1997) 1.49

Elevated levels of interleukin-13 and IL-18 in patients with dengue hemorrhagic fever. FEMS Immunol Med Microbiol (2001) 1.42

Expression of IFN-inducible protein-10 in chronic hepatitis. J Immunol (1997) 1.40

Association between sex, nutritional status, severity of dengue hemorrhagic fever, and immune status in infants with dengue hemorrhagic fever. Am J Trop Med Hyg (2005) 1.34

Increased production of interleukin-8 in primary human monocytes and in human epithelial and endothelial cell lines after dengue virus challenge. J Virol (2002) 1.29

Clinical findings and pro-inflammatory cytokines in dengue patients in Western India: a facility-based study. PLoS One (2010) 1.23

NK cells, displaying early activation, cytotoxicity and adhesion molecules, are associated with mild dengue disease. Clin Exp Immunol (2006) 1.22

Classical dengue hemorrhagic fever resulting from two dengue infections spaced 20 years or more apart: Havana, Dengue 3 epidemic, 2001-2002. Int J Infect Dis (2005) 1.17

Monocyte chemoattractant protein 1 (MCP-1) expression occurs in toxic rat liver injury and human liver disease. J Leukoc Biol (1994) 1.15

Imbalanced intrahepatic expression of interleukin 12, interferon gamma, and interleukin 10 in fulminant hepatitis B. Hepatology (2002) 1.15

Rapid detection and serotyping of dengue virus by multiplex RT-PCR and real-time SYBR green RT-PCR. Singapore Med J (2007) 1.14

Regulation of hepatocyte fate by interferon-γ. Cytokine Growth Factor Rev (2011) 1.13

IL-13 activates STAT6 and inhibits liver injury induced by ischemia/reperfusion. Am J Pathol (1999) 1.11

Differentiating dengue virus infection from scrub typhus in Thai adults with fever. Am J Trop Med Hyg (2003) 1.11

Vascular endothelial growth factor (VEGF) stimulates monocyte migration through endothelial monolayers via increased integrin expression. Eur J Cell Biol (2000) 1.10

Gene expression profiling of dengue infected human primary cells identifies secreted mediators in vivo. J Med Virol (2009) 1.08

Interleukin-1 receptor antagonist (IL-1RN) genotype modulates the replicative capacity of human endothelial cells. Circ Res (2003) 0.92

Serum levels of sICAM-1 and sE-selectin in patients with dengue virus infection. Jpn J Infect Dis (2006) 0.92

Evidence of vascular damage in dengue disease: demonstration of high levels of soluble cell adhesion molecules and circulating endothelial cells. Endothelium (2006) 0.92

Modulation of human endothelial cell permeability by combinations of the cytokines interleukin-1 alpha/beta, tumor necrosis factor-alpha and interferon-gamma. Immunopharmacology (1993) 0.92

Interleukin-4 (IL-4) and IL-13 suppress excessive neutrophil infiltration and hepatocyte damage during acute murine schistosomiasis japonica. Infect Immun (2011) 0.91

ICAM-1 is involved in the mechanism of alcohol-induced liver injury: studies with knockout mice. Am J Physiol Gastrointest Liver Physiol (2001) 0.90

MCP-1 and MIP-1α expression in a model resembling early immune response to dengue. Cytokine (2010) 0.88

Eotaxin increases monolayer permeability of human coronary artery endothelial cells. Arterioscler Thromb Vasc Biol (2009) 0.87

Molecular profiling of T-helper immune genes during dengue virus infection. Virol J (2008) 0.86

Relationship of serum interleukin-7 concentration and the coagulation state in children with nephrotic syndrome. Pediatr Int (2005) 0.86

IL-10 stimulates production of platelet-activating factor by monocytes of patients with active systemic lupus erythematosus (SLE). Clin Exp Immunol (2000) 0.84

IL-4 and reactive oxygen species are elevated in Egyptian patients affected with schistosomal liver disease. Parasite Immunol (2008) 0.82

Regulation by IL-5 of expression of functional platelet-activating factor receptors on human eosinophils. J Immunol (1996) 0.82

Serum interleukin-12 levels in alcoholic liver disease. J Chin Med Assoc (2010) 0.80

Shift to Th2 cytokine response in dengue haemorrhagic fever. Indian J Med Res (2009) 0.79

Relationship between circulating interleukin-10 and histological features in patients with chronic C hepatitis. Ann Saudi Med (2011) 0.78

Articles by these authors

Antibodies against prM protein distinguish between previous infection with dengue and Japanese encephalitis viruses. BMC Microbiol (2002) 2.62

Multi-country evaluation of the sensitivity and specificity of two commercially-available NS1 ELISA assays for dengue diagnosis. PLoS Negl Trop Dis (2010) 2.33

MULTIPRED: a computational system for prediction of promiscuous HLA binding peptides. Nucleic Acids Res (2005) 2.05

Evolutionarily conserved protein sequences of influenza a viruses, avian and human, as vaccine targets. PLoS One (2007) 1.72

Early diagnosis of Dengue infection using a commercial Dengue Duo rapid test kit for the detection of NS1, IGM, and IGG. Am J Trop Med Hyg (2010) 1.70

The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach. PLoS Negl Trop Dis (2011) 1.64

TLR2-induced cytokine responses may characterize HIV-infected patients experiencing mycobacterial immune restoration disease. AIDS (2011) 1.51

Evaluation of a commercial SD dengue virus NS1 antigen capture enzyme-linked immunosorbent assay kit for early diagnosis of dengue virus infection. J Clin Microbiol (2010) 1.45

Advancing standards for bioinformatics activities: persistence, reproducibility, disambiguation and Minimum Information About a Bioinformatics investigation (MIABi). BMC Genomics (2010) 1.44

Efficacy and safety of a live attenuated, cold-adapted influenza vaccine, trivalent against culture-confirmed influenza in young children in Asia. Pediatr Infect Dis J (2007) 1.39

A proposed minimum skill set for university graduates to meet the informatics needs and challenges of the "-omics" era. BMC Genomics (2009) 1.25

Hemophagocytosis in dengue: comprehensive report of six cases. J Clin Virol (2012) 1.20

Working conditions and health among employees at information technology--enabled services: a review of current evidence. Indian J Med Sci (2006) 1.17

Susceptible and protective HLA class 1 alleles against dengue fever and dengue hemorrhagic fever patients in a Malaysian population. PLoS One (2010) 1.16

CysView: protein classification based on cysteine pairing patterns. Nucleic Acids Res (2004) 1.10

Use of multiple data sources to estimate the economic cost of dengue illness in Malaysia. Am J Trop Med Hyg (2012) 1.08

Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis. PLoS One (2010) 1.05

Detection of quorum sensing signal molecules and identification of an autoinducer synthase gene among biofilm forming clinical isolates of Acinetobacter spp. PLoS One (2012) 1.03

T3SEdb: data warehousing of virulence effectors secreted by the bacterial Type III Secretion System. BMC Bioinformatics (2010) 1.02

Neural models for predicting viral vaccine targets. J Bioinform Comput Biol (2005) 1.00

Automatic synchronization and distribution of biological databases and software over low-bandwidth networks among developing countries. Bioinformatics (2007) 0.99

Antimetastatic effects of Phyllanthus on human lung (A549) and breast (MCF-7) cancer cell lines. PLoS One (2011) 0.99

Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes. BMC Bioinformatics (2008) 0.96

Factors that hinder organ donation: religio-cultural or lack of information and trust. Exp Clin Transplant (2013) 0.95

Inhibition of dengue virus entry and multiplication into monocytes using RNA interference. PLoS Negl Trop Dis (2011) 0.94

Cancers in the TREAT Asia HIV Observational Database (TAHOD): a retrospective analysis of risk factors. J Int AIDS Soc (2010) 0.94

A multinational, randomized, placebo-controlled trial to assess the immunogenicity, safety, and tolerability of live attenuated influenza vaccine coadministered with oral poliovirus vaccine in healthy young children. Vaccine (2009) 0.93

Bioinformatics for venom and toxin sciences. Brief Bioinform (2003) 0.93

Cytokine factors present in dengue patient sera induces alterations of junctional proteins in human endothelial cells. Am J Trop Med Hyg (2012) 0.93

Highly conserved influenza A sequences as T cell epitopes-based vaccine targets to address the viral variability. Hum Vaccin (2011) 0.93

Antibacterial action of a heat-stable form of L-amino acid oxidase isolated from king cobra (Ophiophagus hannah) venom. Comp Biochem Physiol C Toxicol Pharmacol (2010) 0.92

Evaluation of ASSURE® Dengue IgA Rapid Test using dengue-positive and dengue-negative samples. Diagn Microbiol Infect Dis (2010) 0.91

Serological diagnosis of dengue infection in blood plasma using long-range surface plasmon waveguides. Anal Chem (2014) 0.91

Clinicians' diagnostic practice of dengue infections. J Clin Virol (2007) 0.91

The implementation of e-learning tools to enhance undergraduate bioinformatics teaching and learning: a case study in the National University of Singapore. BMC Bioinformatics (2009) 0.89

Simultaneous species identification and detection of methicillin resistance in staphylococci using triplex real-time PCR assay. Diagn Microbiol Infect Dis (2006) 0.86

Effects of cocktail of four local Malaysian medicinal plants (Phyllanthus spp.) against dengue virus 2. BMC Complement Altern Med (2013) 0.86

Conservation and variability of West Nile virus proteins. PLoS One (2009) 0.85

Dendritic cell mediated delivery of plasmid DNA encoding LAMP/HIV-1 Gag fusion immunogen enhances T cell epitope responses in HLA DR4 transgenic mice. PLoS One (2010) 0.84

RNA interference mediated inhibition of dengue virus multiplication and entry in HepG2 cells. PLoS One (2012) 0.84

The influence of socioeconomic and demographic variables on willingness to donate cadaveric human organs in Malaysia. Medicine (Baltimore) (2014) 0.84

Capsular serotype and antibiotic resistance of Streptococcus pneumoniae isolates in Malaysia. PLoS One (2011) 0.84

Possible mechanism of pesticide toxicity-related oxidative stress leading to airway narrowing. Redox Rep (2006) 0.84

Development of conventional and real-time multiplex PCR assays for the detection of nosocomial pathogens. Braz J Microbiol (2011) 0.83

The antioxidant effect of the Malaysian Gelam honey on pancreatic hamster cells cultured under hyperglycemic conditions. Clin Exp Med (2013) 0.83

Detection and characterization of class 1 integrons among carbapenem-resistant isolates of Acinetobacter spp. in Malaysia. J Microbiol Immunol Infect (2009) 0.83

Development of ASSURE Dengue IgA Rapid Test for the Detection of Anti-dengue IgA from Dengue Infected Patients. J Glob Infect Dis (2011) 0.83

Cardiovascular disease risk factors and socioeconomic variables in a nation undergoing epidemiologic transition. BMC Public Health (2013) 0.83

Dengue infection and miscarriage: a prospective case control study. PLoS Negl Trop Dis (2012) 0.83

Prevalence and antibiotic susceptibility of bacteria from acute and chronic wounds in Malaysian subjects. J Infect Dev Ctries (2015) 0.82

Phyllanthus Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NFκB, and Hypoxia). Evid Based Complement Alternat Med (2013) 0.82

West Nile virus T-cell ligand sequences shared with other flaviviruses: a multitude of variant sequences as potential altered peptide ligands. J Virol (2012) 0.82

New development in the diagnosis of dengue infections. Expert Opin Med Diagn (2012) 0.82

Oil palm phenolics attenuate changes caused by an atherogenic diet in mice. Eur J Nutr (2012) 0.82

Clinical and immunological markers of dengue progression in a study cohort from a hyperendemic area in Malaysia. PLoS One (2014) 0.81

Positive outcomes of oil palm phenolics on degenerative diseases in animal models. Br J Nutr (2011) 0.81

Dissecting the dynamics of HIV-1 protein sequence diversity. PLoS One (2013) 0.80

Evaluation of antiviral activities of four local Malaysian Phyllanthus species against herpes simplex viruses and possible antiviral target. Int J Med Sci (2013) 0.80

Identification of conserved and HLA promiscuous DENV3 T-cell epitopes. PLoS Negl Trop Dis (2013) 0.80

Caffeic acid phenethyl ester (CAPE): scavenger of peroxynitrite in vitro and in sepsis models. Shock (2014) 0.80

Differential transcriptomic profiles effected by oil palm phenolics indicate novel health outcomes. BMC Genomics (2011) 0.80

Plasma interleukin-18 levels are a biomarker of innate immune responses that predict and characterize tuberculosis-associated immune reconstitution inflammatory syndrome. AIDS (2015) 0.79

Inhibition of Raf-MEK-ERK and hypoxia pathways by Phyllanthus prevents metastasis in human lung (A549) cancer cell line. BMC Complement Altern Med (2013) 0.79

Classification of dengue fever patients based on gene expression data using support vector machines. PLoS One (2010) 0.79

The epidemiology of pneumococcal carriage and infections in Malaysia. Expert Rev Anti Infect Ther (2012) 0.78

Cheminformatics-based drug design approach for identification of inhibitors targeting the characteristic residues of MMP-13 hemopexin domain. PLoS One (2010) 0.78

Severe Plasmodium falciparum infection mimicking acute myocardial infarction. Malar J (2014) 0.78

g-FLUA2H: a web-based application to study the dynamics of animal-to-human mutation transmission for influenza viruses. BMC Med Genomics (2015) 0.78

Detection of mecA and ermA genes and simultaneous identification of Staphylococcus aureus using triplex real-time PCR from Malaysian S. aureus strain collections. Int J Antimicrob Agents (2007) 0.78

Regular paracetamol in severe dengue: a lethal combination? Singapore Med J (2013) 0.78

Detection of pbp2b and ermB genes in clinical isolates of Streptococcus pneumoniae. J Infect Dev Ctries (2008) 0.78

Image Outlier Detection and Feature Extraction via L1-Norm-Based 2D Probabilistic PCA. IEEE Trans Image Process (2015) 0.77

Detection of methicillin- and aminoglycoside-resistant genes and simultaneous identification of S. aureus using triplex real-time PCR Taqman assay. J Microbiol Methods (2006) 0.77

Inhibition of dengue virus entry into target cells using synthetic antiviral peptides. Int J Med Sci (2013) 0.77

Occurrence and characterization of Candida nivariensis from a culture collection of Candida glabrata clinical isolates in Malaysia. Mycopathologia (2014) 0.77

Comparison of Pediatric Severe Sepsis Managed in U.S. and European ICUs. Pediatr Crit Care Med (2016) 0.77

Expression analysis of adherence-associated genes in pneumococcal clinical isolates during adherence to human respiratory epithelial cells (in vitro) by real-time PCR. FEMS Microbiol Lett (2008) 0.77

Simple re-instantiation of small databases using cloud computing. BMC Genomics (2013) 0.77

Gene expression changes in spleens and livers of tumour-bearing mice suggest delayed inflammation and attenuated cachexia in response to oil palm phenolics. J Nutrigenet Nutrigenomics (2014) 0.76

Cervical abscesses due to co-infection with Burkholderia pseudomallei, Salmonella enterica serovar Stanley and Mycobacterium tuberculosis in a patient with diabetes mellitus. BMC Infect Dis (2013) 0.76

Genetic characterization of dengue virus type 1 isolated in Brunei in 2005-2006. J Gen Virol (2009) 0.76

Phyllanthus spp. Exerts Anti-Angiogenic and Anti-Metastatic Effects Through Inhibition on Matrix Metalloproteinase Enzymes. Nutr Cancer (2015) 0.76

Systematic analysis of snake neurotoxins' functional classification using a data warehousing approach. Bioinformatics (2004) 0.76