Published in Phys Med on January 11, 2013
The vasorelaxant effect of H(2)S as a novel endogenous gaseous K(ATP) channel opener. EMBO J (2001) 7.97
A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity. Nature (2001) 7.35
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo. Neuron (1996) 5.30
Direct fluorescence analysis of genetic polymorphisms by hybridization with oligonucleotide arrays on glass supports. Nucleic Acids Res (1994) 4.77
Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease. J Biol Chem (1993) 3.52
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. Neurobiol Dis (2000) 3.46
HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages. Nat Med (1999) 3.01
Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc Natl Acad Sci U S A (1993) 2.79
Cadmium and iron transport by members of a plant metal transporter family in Arabidopsis with homology to Nramp genes. Proc Natl Acad Sci U S A (2000) 2.70
Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer. Br J Cancer (2009) 2.39
The Pendred syndrome gene encodes a chloride-iodide transport protein. Nat Genet (1999) 2.32
Stoichiometry of a recombinant GABAA receptor. J Neurosci (1996) 2.23
Cholangiocarcinoma in patients with primary sclerosing cholangitis: a multicenter case-control study. Hepatology (2000) 2.21
Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides. Nat Med (1998) 2.20
Quantitative trait loci for refractoriness of Anopheles gambiae to Plasmodium cynomolgi B. Science (1997) 2.08
A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease. Neurobiol Dis (2001) 2.07
Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation. Proc Natl Acad Sci U S A (1997) 2.03
Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling. J Neurosci (2001) 1.95
Predictors of large esophageal varices in patients with cirrhosis. Am J Gastroenterol (1999) 1.93
Use of serial proton magnetic resonance spectroscopy to differentiate low grade glioma from tumefactive plaque in a patient with multiple sclerosis. Br J Radiol (2003) 1.92
Reactivation of insulin-like growth factor binding protein 2 expression in glioblastoma multiforme: a revelation by parallel gene expression profiling. Cancer Res (1999) 1.88
Protein ladder sequencing. Science (1993) 1.66
Anthropogenic impacts on the distribution and biodiversity of benthic macroinvertebrates and water quality of the Langat River, Peninsular Malaysia. Ecotoxicol Environ Saf (2005) 1.61
A protein from human placental nuclei binds preferentially to 5-methylcytosine-rich DNA. Nature (1984) 1.61
Identification of receptors for neuromedin U and its role in feeding. Nature (2000) 1.60
Search for supersymmetry using final states with one lepton, jets, and missing transverse momentum with the ATLAS detector in √s=7 TeV pp collisions. Phys Rev Lett (2011) 1.60
Dyspepsia and irritable bowel syndrome in China: a population-based endoscopy study of prevalence and impact. Aliment Pharmacol Ther (2010) 1.59
Critical role of c-Kit in beta cell function: increased insulin secretion and protection against diabetes in a mouse model. Diabetologia (2012) 1.58
Transcription factor expression in the developing human fetal endocrine pancreas. Diabetologia (2008) 1.57
Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia. Nat Neurosci (1999) 1.53
Regulation of Rad51 function by c-Abl in response to DNA damage. J Biol Chem (1998) 1.53
The alteration of serum potassium level during sample transit. Practitioner (1989) 1.51
Biological monitoring of dichloropropene: air concentrations, urinary metabolite, and renal enzyme excretion. Arch Environ Health (1989) 1.50
Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein. Proc Natl Acad Sci U S A (1999) 1.46
Cigarettes and alcohol in relation to colorectal cancer: the Singapore Chinese Health Study. Br J Cancer (2007) 1.46
Interactions between heterologous FtsA and FtsZ proteins at the FtsZ ring. J Bacteriol (1997) 1.45
Cell loss in isolated human islets occurs by apoptosis. Pancreas (2000) 1.45
Fas-mediated cell death promoted by opioids. Nature (1999) 1.45
Generation and regulation of beta-amyloid peptide variants by neurons. J Neurochem (1998) 1.43
The Arabidopsis dual-affinity nitrate transporter gene AtNRT1.1 (CHL1) is activated and functions in nascent organ development during vegetative and reproductive growth. Plant Cell (2001) 1.43
Processing of a cellular prion protein: identification of N- and C-terminal cleavage sites. Biochemistry (1993) 1.42
Suppression of a P450 hydroxylase gene in plant trichome glands enhances natural-product-based aphid resistance. Nat Biotechnol (2001) 1.42
Prolongation of prothrombin time with ivermectin. Lancet (1988) 1.41
Cell-free assays for gamma-secretase activity. FASEB J (2000) 1.41
Family-based intervention for schizophrenic patients in China. A randomised controlled trial. Br J Psychiatry (1994) 1.41
Isolation of an ftsZ homolog from the archaebacterium Halobacterium salinarium: implications for the evolution of FtsZ and tubulin. J Bacteriol (1996) 1.40
High levels of plasma IL-10 and expression of IL-10 by keratinocytes during visceral leishmaniasis predict subsequent development of post-kala-azar dermal leishmaniasis. Clin Exp Immunol (1998) 1.40
Olanzapine versus placebo in the treatment of acute mania. Olanzapine HGEH Study Group. Am J Psychiatry (1999) 1.40
[Effort phlebitis of the upper limb. Report of 5 cases]. J Mal Vasc (2001) 1.39
Measurement of dijet azimuthal decorrelations in pp collisions at sqrt(s)=7 TeV. Phys Rev Lett (2011) 1.39
Recalculation of the temperature inside capillaries using high buffer concentrations. J Chromatogr A (2001) 1.39
Recommendations regarding total daily fluoride intake for Canadians. J Can Dent Assoc (1994) 1.39
Long-term evaluation of composite sequential bypass for limb-threatening ischemia. J Vasc Surg (1992) 1.39
Placement and replacement of restorations in a military population. J Can Dent Assoc (1991) 1.38
Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes. Neurobiol Dis (1999) 1.38
Quantitative structure-activity relationship analysis of phenolic antioxidants. Free Radic Biol Med (1999) 1.35
PTEN mutations are uncommon in Proteus syndrome. J Med Genet (2001) 1.35
Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34
Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers. Vaccine (2000) 1.34
Identification of the gene (lgtG) encoding the lipooligosaccharide beta chain synthesizing glucosyl transferase from Neisseria gonorrhoeae. Proc Natl Acad Sci U S A (1998) 1.33
Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells. Eur J Immunol (1993) 1.33
Identification of urotensin II as the endogenous ligand for the orphan G-protein-coupled receptor GPR14. Biochem Biophys Res Commun (1999) 1.32
Functional differences of the PDS gene product are associated with phenotypic variation in patients with Pendred syndrome and non-syndromic hearing loss (DFNB4). Hum Mol Genet (2000) 1.30
Identification of a tyrosinase epitope recognized by HLA-A24-restricted, tumor-infiltrating lymphocytes. J Immunol (1995) 1.29
Methylphenidate enhances brain activation and deactivation responses to visual attention and working memory tasks in healthy controls. Neuroimage (2010) 1.28
Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27
Gene expression patterns during intramuscular fat development in cattle. J Anim Sci (2008) 1.27
Application of cereals and cereal components in functional foods: a review. Int J Food Microbiol (2002) 1.26
Identification and cloning of an orphan G protein-coupled receptor of the glycoprotein hormone receptor subfamily. Biochem Biophys Res Commun (1998) 1.26
Endocytosis and vesicle trafficking during tip growth of root hairs. Protoplasma (2005) 1.24
gamma-Secretase, evidence for multiple proteolytic activities and influence of membrane positioning of substrate on generation of amyloid beta peptides of varying length. J Biol Chem (1999) 1.24
Immunohistochemical characterisation of cells co-producing insulin and glucagon in the developing human pancreas. Diabetologia (2011) 1.23
Presenilin 1 regulates pharmacologically distinct gamma -secretase activities. Implications for the role of presenilin in gamma -secretase cleavage. J Biol Chem (2000) 1.22
Structural homology between the Rap30 DNA-binding domain and linker histone H5: implications for preinitiation complex assembly. Proc Natl Acad Sci U S A (1998) 1.21
FMRFamide-related neuropeptides are agonists of the orphan G-protein-coupled receptor GPR54. Biochem Biophys Res Commun (2001) 1.20
Identification and characterization of novel mammalian neuropeptide FF-like peptides that attenuate morphine-induced antinociception. J Biol Chem (2001) 1.20
Highly spin-polarized room-temperature tunnel injector for semiconductor spintronics using MgO(100). Phys Rev Lett (2005) 1.20
Purple urine bag syndrome in a hemodialysis patient. Kidney Int (2007) 1.20
Search for dark matter candidates and large extra dimensions in events with a photon and missing transverse momentum in pp collision data at sqrt[s]=7 TeV with the ATLAS detector. Phys Rev Lett (2013) 1.19
Risks of lung cancer, chronic bronchitis, ischaemic heart disease, and stroke in relation to type of cigarette smoked. J Epidemiol Community Health (1985) 1.19
Hepatitis B control in China: knowledge and practices among village doctors. Am J Public Health (1993) 1.19
Kala-azar in a high transmission focus: an ethnic and geographic dimension. Am J Trop Med Hyg (1999) 1.19
Brain viral burden in HIV infection. J Neuropathol Exp Neurol (1994) 1.18
Expression of voltage-dependent K(+) channel genes in mesenteric artery smooth muscle cells. Am J Physiol (1999) 1.18
The risks and benefits of clozapine versus chlorpromazine. J Clin Psychopharmacol (1987) 1.17
Effect of forkhead box O1 (FOXO1) on beta cell development in the human fetal pancreas. Diabetologia (2009) 1.17
A hybrid human and machine resource curation pipeline for the Neuroscience Information Framework. Database (Oxford) (2012) 1.16
Dichotomy of the human T cell response to Leishmania antigens. I. Th1-like response to Leishmania major promastigote antigens in individuals recovered from cutaneous leishmaniasis. Clin Exp Immunol (1994) 1.16
Nonfibrillar diffuse amyloid deposition due to a gamma(42)-secretase site mutation points to an essential role for N-truncated A beta(42) in Alzheimer's disease. Hum Mol Genet (2000) 1.15
Regulation of cell growth by IL-2: role of STAT5 in protection from apoptosis but not in cell cycle progression. J Immunol (1998) 1.15
Epidemiology of functional constipation and comparison with constipation-predominant irritable bowel syndrome: the Systematic Investigation of Gastrointestinal Diseases in China (SILC). Aliment Pharmacol Ther (2011) 1.14
A lipopolysaccharide- and beta-1,3-glucan-binding protein from hemocytes of the freshwater crayfish Pacifastacus leniusculus. Purification, characterization, and cDNA cloning. J Biol Chem (2000) 1.14
Collagen fibril surface displays a constellation of sites capable of promoting fibril assembly, stability, and hemostasis. Connect Tissue Res (2010) 1.14
Search for a supersymmetric partner to the top quark in final states with jets and missing transverse momentum at sqrt[s] = 7 TeV with the ATLAS detector. Phys Rev Lett (2012) 1.13
Protection of mice against Plasmodium yoelii sporozoite challenge with P. yoelii merozoite surface protein 1 DNA vaccines. Infect Immun (1998) 1.12
The crayfish plasma clotting protein: a vitellogenin-related protein responsible for clot formation in crustacean blood. Proc Natl Acad Sci U S A (1999) 1.12