Published in Transl Psychiatry on January 15, 2013
Neural plasticity and proliferation in the generation of antidepressant effects: hippocampal implication. Neural Plast (2013) 0.96
Therapeutic antidepressant potential of a conjugated siRNA silencing the serotonin transporter after intranasal administration. Mol Psychiatry (2015) 0.89
Targeting intestinal inflammation with CD98 siRNA/PEI-loaded nanoparticles. Mol Ther (2013) 0.84
Increased brain-derived neurotrophic factor (BDNF) protein concentrations in mice lacking brain serotonin. Eur Arch Psychiatry Clin Neurosci (2015) 0.83
A critical evaluation of the activity-regulated cytoskeleton-associated protein (Arc/Arg3.1)'s putative role in regulating dendritic plasticity, cognitive processes, and mood in animal models of depression. Front Neurosci (2015) 0.80
Stress-induced neuroinflammation is mediated by GSK3-dependent TLR4 signaling that promotes susceptibility to depression-like behavior. Brain Behav Immun (2016) 0.77
Glial GLT-1 blockade in infralimbic cortex as a new strategy to evoke rapid antidepressant-like effects in rats. Transl Psychiatry (2017) 0.75
Divergent Roles of Central Serotonin in Adult Hippocampal Neurogenesis. Front Cell Neurosci (2017) 0.75
Response of Htr3a knockout mice to antidepressant treatment and chronic stress. Br J Pharmacol (2017) 0.75
Novel 5-HT3 receptor antagonist QCM-4 attenuates depressive-like phenotype associated with obesity in high-fat-diet-fed mice. Psychopharmacology (Berl) (2017) 0.75
Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry (2005) 45.33
MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet (2004) 37.83
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science (2003) 28.61
The Ki-67 protein: from the known and the unknown. J Cell Physiol (2000) 16.48
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science (2003) 16.14
Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science (1996) 16.04
Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry (2006) 12.41
The molecular neurobiology of depression. Nature (2008) 6.51
Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am J Hum Genet (2006) 6.27
Medication augmentation after the failure of SSRIs for depression. N Engl J Med (2006) 5.16
Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J Neurosci (1995) 5.10
Adult hippocampal neurogenesis in depression. Nat Neurosci (2007) 4.79
The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. Neurosci Biobehav Rev (2005) 4.64
Plasma membrane monoamine transporters: structure, regulation and function. Nat Rev Neurosci (2003) 4.50
Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice. Science (2004) 4.31
Current advances and trends in the treatment of depression. Trends Pharmacol Sci (1994) 3.49
Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus. J Neurosci (1996) 3.33
The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior. Behav Pharmacol (2007) 3.32
Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine. Mol Psychiatry (1998) 3.07
The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesis. J Neurosci Methods (2002) 2.81
Preclinical models: status of basic research in depression. Biol Psychiatry (2002) 2.76
miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants. Science (2010) 2.75
An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat. J Comp Neurol (1978) 2.63
Research and treatment approaches to depression. Nat Rev Neurosci (2001) 2.24
VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants. Proc Natl Acad Sci U S A (2007) 2.22
Acceleration of the effect of selected antidepressant drugs in major depression by 5-HT1A antagonists. Trends Neurosci (1996) 2.22
Targeting the murine serotonin transporter: insights into human neurobiology. Nat Rev Neurosci (2008) 2.21
Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice. Biol Psychiatry (2003) 1.94
How does pindolol improve antidepressant action? Trends Pharmacol Sci (2001) 1.91
Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants. Science (1999) 1.85
Molecular physiology of norepinephrine and serotonin transporters. J Exp Biol (1994) 1.80
A role for p38 mitogen-activated protein kinase in the regulation of the serotonin transporter: evidence for distinct cellular mechanisms involved in transporter surface expression. J Neurosci (2005) 1.63
Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression. Biol Psychiatry (2003) 1.58
A systematic review of association studies investigating genes coding for serotonin receptors and the serotonin transporter: II. Suicidal behavior. Mol Psychiatry (2003) 1.58
Differential regulation of brain derived neurotrophic factor transcripts by antidepressant treatments in the adult rat brain. Neuropharmacology (2003) 1.53
Co-expression and in vivo interaction of serotonin1A and serotonin2A receptors in pyramidal neurons of prefrontal cortex. Cereb Cortex (2004) 1.48
Effects of chronic antidepressant treatments on serotonin transporter function, density, and mRNA level. J Neurosci (1999) 1.42
Latent stem and progenitor cells in the hippocampus are activated by neural excitation. J Neurosci (2008) 1.39
Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter. Neuropsychopharmacology (2002) 1.39
Serotonin and drug-induced therapeutic responses in major depression, obsessive-compulsive and panic disorders. Neuropsychopharmacology (1999) 1.30
Identification and characterization of antidepressant-sensitive serotonin transporter proteins using site-specific antibodies. J Neurosci (1995) 1.26
Trillion-dollar brain drain. Nature (2011) 1.26
siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain. Mol Psychiatry (2005) 1.23
Relationship between brain serotonin transporter binding, plasma concentration and behavioural effect of selective serotonin reuptake inhibitors. Br J Pharmacol (2005) 1.15
Differential regulation of 5-HT1A receptor-G protein interactions in brain following chronic antidepressant administration. Neuropsychopharmacology (2002) 1.12
Functional mapping of dorsal and median raphe 5-hydroxytryptamine pathways in forebrain of the rat using microdialysis. J Neurochem (1997) 1.11
Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects. Mol Psychiatry (2011) 1.11
Serotonin clearance in vivo is altered to a greater extent by antidepressant-induced downregulation of the serotonin transporter than by acute blockade of this transporter. J Neurosci (2002) 1.06
Preferential potentiation of the effects of serotonin uptake inhibitors by 5-HT1A receptor antagonists in the dorsal raphe pathway: role of somatodendritic autoreceptors. J Neurochem (1997) 1.01
Acute 5-HT₁A autoreceptor knockdown increases antidepressant responses and serotonin release in stressful conditions. Psychopharmacology (Berl) (2012) 1.01
Delayed pharmacological effects of antidepressants. Mol Psychiatry (2002) 1.00
RNA interference: a tool for querying nervous system function and an emerging therapy. Neuron (2007) 1.00
Chronic fluoxetine induces opposite changes in G protein coupling at pre and postsynaptic 5-HT1A receptors in rat brain. Neuropharmacology (2003) 0.99
Paradoxical anxiogenic response of juvenile mice to fluoxetine. Neuropsychopharmacology (2009) 0.99
Desensitization of the neuronal 5-HT carrier following its long-term blockade. J Neurosci (1994) 0.99
Increased responsiveness of presumed 5-HT cells to citalopram in adult rats subjected to prolonged maternal separation relative to brief separation. Psychopharmacology (Berl) (2004) 0.96
Ultrastructural localization of the serotonin transporter in limbic and motor compartments of the nucleus accumbens. J Neurosci (1999) 0.94
Factors affecting fluvoxamine antidepressant activity: influence of pindolol and 5-HTTLPR in delusional and nondelusional depression. Biol Psychiatry (2001) 0.93
Effects of chronic antidepressant treatments on 5-HT and NA transporters in rat brain: an autoradiographic study. Neurochem Int (2001) 0.92
Antidepressant-induced internalization of the serotonin transporter in serotonergic neurons. FASEB J (2008) 0.90
Association of changes in norepinephrine and serotonin transporter expression with the long-term behavioral effects of antidepressant drugs. Neuropsychopharmacology (2008) 0.88
Antidepressant drug treatment induces Arc gene expression in the rat brain. Neuroscience (2003) 0.87
Neurotransmitter transporters synthesis and degradation rates. Life Sci (2001) 0.78
Complex polysaccharides as PCR inhibitors in feces: Helicobacter pylori model. J Clin Microbiol (1997) 3.57
Randomised, double-blind, placebo-controlled trial of pindolol in combination with fluoxetine antidepressant treatment. Lancet (1997) 3.12
Effect of exacerbations on quality of life in patients with chronic obstructive pulmonary disease: a 2 year follow up study. Thorax (2004) 2.78
Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors. Brain Res (1985) 2.68
5-HT and antidepressants: new views from microdialysis studies. Trends Pharmacol Sci (1993) 2.65
[Current status of tuberculosis in Spain. A precarious health care perspective with regard to developed countries]. Med Clin (Barc) (1995) 2.58
Pindolol induces a rapid improvement of depressed patients treated with serotonin reuptake inhibitors. Arch Gen Psychiatry (1994) 2.54
[The use of human gamma globulin in the treatment of common variable immunodeficiency]. Med Clin (Barc) (1995) 2.04
Control of dorsal raphe serotonergic neurons by the medial prefrontal cortex: Involvement of serotonin-1A, GABA(A), and glutamate receptors. J Neurosci (2001) 1.92
Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides. Biochem J (2000) 1.84
Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors. Brain Res (1985) 1.81
The binding of serotonergic ligands to the porcine choroid plexus: characterization of a new type of serotonin recognition site. Eur J Pharmacol (1984) 1.79
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
The influence of intravenous drug use and HIV infection in the transmission of tuberculosis. AIDS (1996) 1.60
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
Results of a case-detection programme for alpha1-antitrypsin deficiency in COPD patients. Eur Respir J (2005) 1.51
Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues. Am J Pathol (1998) 1.48
The primary structure of rat ribosomal protein S8. Nucleic Acids Res (1987) 1.48
Atopy and serum eosinophil cationic protein in 110 white children with vernal keratoconjunctivitis: differences between tarsal and limbal forms. Clin Exp Allergy (2003) 1.47
Autoradiographic distribution of [3H]sumatriptan-binding sites in post-mortem human brain. Cephalalgia (1996) 1.44
Neurological disorders associated with Aujeszky's disease virus infection in fattening pigs. Vet Rec (2003) 1.43
Pretreatment platelet 5-HT concentration predicts the short-term response to paroxetine in major depression. Grupo de Trastornos Afectivos. Biol Psychiatry (1999) 1.40
Observation of B(0)(s)-->Psi(2S)Phi and measurement of the ratio of branching fractions Beta(B(0)(s)-->Psi(2S)Phi)/Beta(B(0)(s)-->J/PsiPhi). Phys Rev Lett (2006) 1.40
The distribution of adenosine A1 receptors and 5'-nucleotidase in the brain of some commonly used experimental animals. Neuroscience (1987) 1.39
Serotonergic status in human blood. Life Sci (1988) 1.38
Control of serotonergic function in medial prefrontal cortex by serotonin-2A receptors through a glutamate-dependent mechanism. J Neurosci (2001) 1.29
Synthesis and antiparasitic activity of 2-(trifluoromethyl)-benzimidazole derivatives. Bioorg Med Chem Lett (2001) 1.27
Neuropeptide expression in rat dorsal root ganglion cells and spinal cord after peripheral nerve injury with special reference to galanin. Neuroscience (1989) 1.26
Detection of Helicobacter pylori DNA in human feces by PCR: DNA stability and removal of inhibitors. J Microbiol Methods (2001) 1.25
Measurement of the electron charge asymmetry in inclusive W production in pp collisions at sqrt[s]=7 TeV. Phys Rev Lett (2012) 1.23
Serotonin receptors in the human brain. II. Characterization and autoradiographic localization of 5-HT1C and 5-HT2 recognition sites. Brain Res (1986) 1.22
Serotonin receptors in the human brain--III. Autoradiographic mapping of serotonin-1 receptors. Neuroscience (1987) 1.22
Phosphodiesterase type 4 isozymes expression in human brain examined by in situ hybridization histochemistry and[3H]rolipram binding autoradiography. Comparison with monkey and rat brain. J Chem Neuroanat (2000) 1.20
Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia. Am J Pathol (2001) 1.20
Search for new physics in the multijet and missing transverse momentum final state in proton-proton collisions at √s = 7 TeV. Phys Rev Lett (2012) 1.19
Azimuthal anisotropy of charged particles at high transverse momenta in Pb-Pb collisions at sqrt[s(NN)] = 2.76 TeV. Phys Rev Lett (2012) 1.19
Comparative study in the rat of the actions of different types of stress on the release of 5-HT in raphe nuclei and forebrain areas. Neuropharmacology (1997) 1.15
Differential effects of clomipramine given locally or systemically on extracellular 5-hydroxytryptamine in raphe nuclei and frontal cortex. An in vivo brain microdialysis study. Naunyn Schmiedebergs Arch Pharmacol (1991) 1.15
Clinical evaluation of an in-house IS6110 polymerase chain reaction for diagnosis of tuberculosis. Eur J Clin Microbiol Infect Dis (2000) 1.13
Fluvoxamine preferentially increases extracellular 5-hydroxytryptamine in the raphe nuclei: an in vivo microdialysis study. Eur J Pharmacol (1992) 1.12
Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects. Mol Psychiatry (2011) 1.11
First observation of the decay Bs0-->Ds-Ds+ and measurement of its branching ratio. Phys Rev Lett (2008) 1.11
Role of 5-HT1A autoreceptors in the mechanism of action of serotoninergic antidepressant drugs: recent findings from in vivo microdialysis studies. Fundam Clin Pharmacol (1996) 1.11
Clinicopathologic features of frontotemporal dementia with progranulin sequence variation. Neurology (2007) 1.11
Search for a W' or techni-ρ decaying into WZ in pp Collisions at sqrt[s] = 7 TeV. Phys Rev Lett (2012) 1.10
Atherosclerosis of the thoracic aorta and aortic debris as a marker of poor prognosis: benefit of oral anticoagulants. J Am Coll Cardiol (1999) 1.10
Search for new physics with same-sign isolated dilepton events with jets and missing transverse energy. Phys Rev Lett (2012) 1.09
Dopamine receptors in human brain: autoradiographic distribution of D2 sites. Neuroscience (1989) 1.08
Search for supersymmetry at the LHC in events with jets and missing transverse energy. Phys Rev Lett (2011) 1.08
A mutation in myotilin causes spheroid body myopathy. Neurology (2005) 1.07
Measurement of sigma chi c2 B(chi c2-->J/psi gamma)/sigma chi c1 B(chi c1 -->J/psi gamma) in pp collisions at square root s=1.96 TeV. Phys Rev Lett (2007) 1.07
Search for stopped Gluinos in pp collisions at square root s=7 TeV. Phys Rev Lett (2011) 1.07
The distribution of glycine receptors in the human brain. A light microscopic autoradiographic study using [3H]strychnine. Neuroscience (1986) 1.07
Pharmacological characteristics and anatomical distribution of [3H]oxytocin-binding sites in the Wistar rat brain studied by autoradiography. Neuroscience (1987) 1.06
Calcium antagonist binding sites in the rat brain: quantitative autoradiographic mapping using the 1,4-dihydropyridines [3H]PN 200-110 and [3H]PY 108-068. J Neural Transm (1984) 1.05
Serotonin receptors in the human brain. I. Characterization and autoradiographic localization of 5-HT1A recognition sites. Apparent absence of 5-HT1B recognition sites. Brain Res (1986) 1.05
Measurement of the Υ1S, Υ2S, and Υ3S polarizations in pp collisions at sqrt[s] = 7 TeV. Phys Rev Lett (2013) 1.05
Are Wistar-Kyoto rats a genetic animal model of depression resistant to antidepressants? Eur J Pharmacol (1997) 1.04
Direct measurement of the W production charge asymmetry in pp collisions at square root s=1.96 TeV. Phys Rev Lett (2009) 1.04
Serotonin receptors in the human brain--IV. Autoradiographic mapping of serotonin-2 receptors. Neuroscience (1987) 1.03
Search for long-lived massive charged particles in 1.96 TeV pp collisions. Phys Rev Lett (2009) 1.03
Esophageal dysplasias are detected by endoscopy with Lugol in patients at risk for squamous cell carcinoma in southern Brazil. Dis Esophagus (1999) 1.02
Measurement of d sigma/dM and forward-backward charge asymmetry for high-mass Drell-Yan e(+)e(-) pairs from pp macro collisions at square root of s = 1.8 TeV. Phys Rev Lett (2001) 1.02
Amyloid and nonfibrillar deposits in mice transgenic for wild-type human transthyretin: a possible model for senile systemic amyloidosis. Lab Invest (2001) 1.02
Benzodiazepine receptor sites in the human brain: autoradiographic mapping. Neuroscience (1988) 1.02
Effect of pindolol on the function of pre- and postsynaptic 5-HT1A receptors: in vivo microdialysis and electrophysiological studies in the rat brain. Neuropsychopharmacology (1996) 1.01
Evidence for species differences in 'peripheral' benzodiazepine receptors: an autoradiographic study. Neurosci Lett (1986) 1.01
Preferential potentiation of the effects of serotonin uptake inhibitors by 5-HT1A receptor antagonists in the dorsal raphe pathway: role of somatodendritic autoreceptors. J Neurochem (1997) 1.01
How long should pindolol be associated with paroxetine to improve the antidepressant response? J Clin Psychopharmacol (1997) 1.00
Mesulergine, a selective serotonin-2 ligand in the rat cortex, does not label these receptors in porcine and human cortex: evidence for species differences in brain serotonin-2 receptors. Eur J Pharmacol (1984) 1.00
Observation of Bs(0)-Bs(0) oscillations. Phys Rev Lett (2006) 1.00
Dopamine receptors in human brain: autoradiographic distribution of D1 sites. Neuroscience (1989) 1.00
Severe hepatotoxicity due to anti-tuberculosis drugs in Spain. Int J Tuberc Lung Dis (2005) 0.99
Measurement of the polarization of W bosons with large transverse momenta in W + jets events at the LHC. Phys Rev Lett (2011) 0.99
Dopamine- and cAMP-regulated phosphoprotein (DARPP-32) and dopamine DA1 agonist-sensitive Na+,K+-ATPase in renal tubule cells. Proc Natl Acad Sci U S A (1989) 0.99
Hemorrhagic dengue with spontaneous splenic rupture: case report and review. Clin Infect Dis (1997) 0.99
Autoradiography of antidepressant binding sites in the human brain: localization using [3H]imipramine and [3H]paroxetine. Neuroscience (1988) 0.98
Troponin I and risk stratification of patients with acute nonmassive pulmonary embolism. Eur Respir J (2007) 0.98
Measurement of the inclusive jet cross section in pp collisions at √s = 7 TeV. Phys Rev Lett (2011) 0.98
Epitope map of two polyclonal antibodies that recognize amyloid lesions in patients with Alzheimer's disease. Biochem J (1992) 0.98
Selective increase of alpha2A-adrenoceptor agonist binding sites in brains of depressed suicide victims. J Neurochem (1998) 0.98
Search for neutral minimal supersymmetric standard model Higgs bosons decaying to tau pairs in pp collisions at √s=7 TeV. Phys Rev Lett (2011) 0.97
Light chain cardiomyopathy. Structural analysis of the light chain tissue deposits. Am J Pathol (1996) 0.97
The primary structure of rat ribosomal protein S24. FEBS Lett (1990) 0.97
The role of 5-HT1B receptors in the regulation of serotonin cell firing and release in the rat brain. J Neurochem (2001) 0.97
Search for large extra dimensions in final states containing one photon or jet and large missing transverse energy produced in pp collisions at square root[s]=1.96 TeV. Phys Rev Lett (2008) 0.97
Polarizations of J/psi and psi(2S) mesons produced in pp collisions at square root s = 1.96 TeV. Phys Rev Lett (2007) 0.96
Muscarinic cholinergic receptor subtypes in the rat brain. I. Quantitative autoradiographic studies. Brain Res (1986) 0.96
The primary structure of rat ribosomal protein S16. FEBS Lett (1990) 0.96
Structural analysis and magnetic properties of the 1D and 3D compounds [Mn(dca)2nbipym] (M = Mn, Cu; dca = dicyanamide; bipym = bipyrimidine; n = 1,2). Inorg Chem (2001) 0.96
4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-gamma-stimulated monocytes (THP-1 cells). Biochem J (1993) 0.96
Measurement of associated production of vector bosons and top quark-antiquark pairs in pp collisions at sqrt[s]=7 TeV. Phys Rev Lett (2013) 0.95
Measurement of the top-quark mass in all-hadronic decays in pp collisions at CDF II. Phys Rev Lett (2007) 0.95
Search for dark matter and large extra dimensions in pp collisions yielding a photon and missing transverse energy. Phys Rev Lett (2012) 0.95
Measurement of the strong coupling constant from inclusive jet production at the Tevatron pp collider. Phys Rev Lett (2002) 0.94