Published in Immunogenetics on January 29, 2013
The effect of genetic bottlenecks and inbreeding on the incidence of two major autoimmune diseases in standard poodles, sebaceous adenitis and Addison's disease. Canine Genet Epidemiol (2015) 0.85
Autoantibodies against Cytochrome P450 Side-Chain Cleavage Enzyme in Dogs (Canis lupus familiaris) Affected with Hypoadrenocorticism (Addison's Disease). PLoS One (2015) 0.78
Clinical features of hypoadrenocorticism in soft-coated wheaten terrier dogs: 82 cases (1979-2013). Can Vet J (2016) 0.77
Naturally Occurring Adrenocortical Insufficiency - An Epidemiological Study Based on a Swedish-Insured Dog Population of 525,028 Dogs. J Vet Intern Med (2015) 0.77
Evaluation of a DLA-79 allele associated with multiple immune-mediated diseases in dogs. Immunogenetics (2015) 0.75
Analysis of DLA-DQB1 and polymorphisms in CTLA4 in Cocker spaniels affected with immune-mediated haemolytic anaemia. Canine Genet Epidemiol (2015) 0.75
HLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course. Am J Hum Genet (2003) 2.02
Is the prevalence of Addison's disease underestimated? J Clin Endocrinol Metab (1999) 1.78
Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency. J Clin Endocrinol Metab (2008) 1.51
Microsatellite polymorphism of the MHC class I chain-related (MIC-A and MIC-B) genes marks the risk for autoimmune Addison's disease. J Clin Endocrinol Metab (1999) 1.45
Understanding the genetics of autoimmune disease: two loci that regulate late onset Addison's disease in Portuguese Water Dogs. Int J Immunogenet (2006) 1.21
High prevalence and increasing incidence of Addison's disease in western Norway. Clin Endocrinol (Oxf) (2002) 1.18
Polymorphisms in the cytotoxic T lymphocyte antigen-4 gene region confer susceptibility to Addison's disease. J Clin Endocrinol Metab (2004) 1.17
Identification of susceptibility and protective major histocompatibility complex haplotypes in canine diabetes mellitus. Tissue Antigens (2006) 1.09
Heritability and complex segregation analysis of hypoadrenocorticism in the standard poodle. J Small Anim Pract (2003) 1.01
Association analysis of the cytotoxic T lymphocyte antigen-4 (CTLA-4) and autoimmune regulator-1 (AIRE-1) genes in sporadic autoimmune Addison's disease. J Clin Endocrinol Metab (2000) 0.99
Necrotizing meningoencephalitis of Pug dogs associates with dog leukocyte antigen class II and resembles acute variant forms of multiple sclerosis. Tissue Antigens (2010) 0.99
Inheritance of hypoadrenocorticism in bearded collies. Am J Vet Res (2002) 0.96
Association of a dog leukocyte antigen class II haplotype with hypoadrenocorticism in Nova Scotia Duck Tolling Retrievers. Tissue Antigens (2010) 0.96
Increased genetic risk or protection for canine autoimmune lymphocytic thyroiditis in Giant Schnauzers depends on DLA class II genotype. Tissue Antigens (2010) 0.94
Multiple loci in the HLA complex are associated with Addison's disease. J Clin Endocrinol Metab (2011) 0.94
Association of a common dog leucocyte antigen class II haplotype with canine primary immune-mediated haemolytic anaemia. Tissue Antigens (2006) 0.93
Risk of anal furunculosis in German shepherd dogs is associated with the major histocompatibility complex. Tissue Antigens (2007) 0.88
Canine hypoadrenocorticism: part I. Can Vet J (2010) 0.87
Association of hypothyroid disease in Doberman Pinscher dogs with a rare major histocompatibility complex DLA class II haplotype. Tissue Antigens (2006) 0.85
21-hydroxylase autoantibodies in adult patients with endocrine autoimmune diseases are highly specific for Addison's disease. Belgian Diabetes Registry. Clin Exp Immunol (1997) 0.84
Examination of candidate genes for hypoadrenocorticism in Nova Scotia Duck Tolling Retrievers. Vet J (2011) 0.81
Adrenal-cortex autoantibodies and steroid-producing cells autoantibodies in patients with Addison's disease: comparison of immunofluorescence and immunoprecipitation assays. J Clin Endocrinol Metab (1999) 0.80
Major histocompatibility complex diversity in the endangered Ethiopian wolf (Canis simensis). Tissue Antigens (2011) 0.80
Canine hypoadrenocorticism: part II. Can Vet J (2010) 0.80
IMGT/HLA and IMGT/MHC: sequence databases for the study of the major histocompatibility complex. Nucleic Acids Res (2003) 5.64
A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs. PLoS Genet (2007) 3.61
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. Lancet (2012) 3.48
Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease. Nat Genet (2010) 3.24
Endotoxin exposure, CD14, and allergic disease: an interaction between genes and the environment. Am J Respir Crit Care Med (2006) 2.41
HLA-DRB1 and persistent chronic inflammation contribute to cardiovascular events and cardiovascular mortality in patients with rheumatoid arthritis. Arthritis Rheum (2007) 2.28
Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1. PLoS Med (2006) 1.98
Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann Rheum Dis (2010) 1.75
The genetic basis of individual-recognition signals in the mouse. Curr Biol (2007) 1.68
The diagnostic utility of myositis autoantibody testing for predicting the risk of cancer-associated myositis. Ann Rheum Dis (2007) 1.66
Mutation screening of the macrophage migration inhibitory factor gene: positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile idiopathic arthritis. Arthritis Rheum (2002) 1.66
Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data. Ann Rheum Dis (2012) 1.62
The genetic basis of inbreeding avoidance in house mice. Curr Biol (2007) 1.61
Epilepsy in Irish Wolfhounds. J Vet Intern Med (2006) 1.60
A variant in MCF2L is associated with osteoarthritis. Am J Hum Genet (2011) 1.60
ISAG/IUIS-VIC Comparative MHC Nomenclature Committee report, 2005. Immunogenetics (2006) 1.52
Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33) predict impaired early-life lung function. Am J Respir Crit Care Med (2005) 1.40
Localization of canine brachycephaly using an across breed mapping approach. PLoS One (2010) 1.33
In adult onset myositis, the presence of interstitial lung disease and myositis specific/associated antibodies are governed by HLA class II haplotype, rather than by myositis subtype. Arthritis Res Ther (2006) 1.23
Factors influencing the antibody response of dogs vaccinated against rabies. Vaccine (2007) 1.22
Genomic sequence of the class II region of the canine MHC: comparison with the MHC of other mammalian species. Genomics (2005) 1.21
Severe papillomavirus infection progressing to metastatic squamous cell carcinoma in bone marrow-transplanted X-linked SCID dogs. J Virol (2006) 1.20
Missense mutation in CAPN1 is associated with spinocerebellar ataxia in the Parson Russell Terrier dog breed. PLoS One (2013) 1.17
Association of FCGR2A and FCGR2A-FCGR3A haplotypes with susceptibility to giant cell arteritis. Arthritis Res Ther (2006) 1.13
Genome-wide association study of dermatomyositis reveals genetic overlap with other autoimmune disorders. Arthritis Rheum (2013) 1.12
Genetic susceptibility to keloid disease and hypertrophic scarring: transforming growth factor beta1 common polymorphisms and plasma levels. Plast Reconstr Surg (2003) 1.06
The direct assessment of genetic heterozygosity through scent in the mouse. Curr Biol (2008) 1.05
Susceptibility to visceral leishmaniasis in the domestic dog is associated with MHC class II polymorphism. Immunogenetics (2003) 1.05
Relationship among the HLA-DRB1 shared epitope, smoking, and rheumatoid factor production in rheumatoid arthritis. Arthritis Rheum (2002) 1.05
Parallel mapping and simultaneous sequencing reveals deletions in BCAN and FAM83H associated with discrete inherited disorders in a domestic dog breed. PLoS Genet (2012) 1.04
Association of symptomatic acute human parvovirus B19 infection with human leukocyte antigen class I and II alleles. J Infect Dis (2002) 1.04
The effect of genome-wide association scan quality control on imputation outcome for common variants. Eur J Hum Genet (2011) 1.04
Genome-wide association study in RPGRIP1(-/-) dogs identifies a modifier locus that determines the onset of retinal degeneration. Mamm Genome (2011) 1.04
Genome-wide mRNA sequencing of a single canine cerebellar cortical degeneration case leads to the identification of a disease associated SPTBN2 mutation. BMC Genet (2012) 1.03
Mutation identification in a canine model of X-linked ectodermal dysplasia. Mamm Genome (2005) 1.03
A frameshift mutation in golden retriever dogs with progressive retinal atrophy endorses SLC4A3 as a candidate gene for human retinal degenerations. PLoS One (2011) 1.03
Echocardiographic and Doppler findings in long-term treated rheumatoid arthritis patients without clinically evident cardiovascular disease. Semin Arthritis Rheum (2004) 1.02
Phenotypic variation and genotype-phenotype discordance in canine cone-rod dystrophy with an RPGRIP1 mutation. Mol Vis (2009) 1.01
Analysis of normal and osteoarthritic canine cartilage mRNA expression by quantitative polymerase chain reaction. Arthritis Res Ther (2006) 1.01
Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies. Arthritis Rheumatol (2014) 1.00
Dogslife: a web-based longitudinal study of Labrador Retriever health in the UK. BMC Vet Res (2013) 0.99
Assessment of the quality and quantity of genomic DNA recovered from canine blood samples by three different extraction methods. Res Vet Sci (2007) 0.99
Molecular phenotypic descriptors of Dupuytren's disease defined using informatics analysis of the transcriptome. J Hand Surg Am (2008) 0.99
MHC class II polymorphism is associated with a canine SLE-related disease complex. Immunogenetics (2009) 0.99
A selective sweep of >8 Mb on chromosome 26 in the Boxer genome. BMC Genomics (2011) 0.98
Polymorphisms in the TLR4 and TLR5 gene are significantly associated with inflammatory bowel disease in German shepherd dogs. PLoS One (2010) 0.98
Programmed death ligand 1 (PD-L1) gene variants contribute to autoimmune Addison's disease and Graves' disease susceptibility. J Clin Endocrinol Metab (2009) 0.97
Recent advances in the immunogenetics of idiopathic inflammatory myopathy. Arthritis Res Ther (2011) 0.97
Dogs really are man's best friend--canine genomics has applications in veterinary and human medicine! Brief Funct Genomic Proteomic (2005) 0.93
Identification of a novel mitochondrial mutation in Dupuytren's disease using multiplex DHPLC. Plast Reconstr Surg (2005) 0.93
Genetic susceptibility to dupuytren disease: association of Zf9 transcription factor gene. Plast Reconstr Surg (2003) 0.93
Sequence analysis of MHC DRB alleles in domestic cats from the United Kingdom. Immunogenetics (2002) 0.93
A candidate gene analysis of canine hypoadrenocorticism in 3 dog breeds. J Hered (2013) 0.93
Denaturing gradient gel electrophoresis analysis of the tissue nonspecific alkaline phosphatase isoenzyme gene in hypophosphatasia. Mol Genet Metab (2002) 0.93
Genetic screening for PRA-associated mutations in multiple dog breeds shows that PRA is heterogeneous within and between breeds. Vet Ophthalmol (2013) 0.92
Genetics of canine diabetes mellitus: are the diabetes susceptibility genes identified in humans involved in breed susceptibility to diabetes mellitus in dogs? Vet J (2012) 0.92
Interleukin 1 receptor antagonist gene polymorphism is associated with severe renal involvement and renal sequelae in Henoch-Schönlein purpura. J Rheumatol (2002) 0.92
Canine Imerslund-Gräsbeck syndrome maps to a region orthologous to HSA14q. Mamm Genome (2003) 0.91
Genome-wide association study identifies a novel canine glaucoma locus. PLoS One (2013) 0.91
Apolipoprotein E genotype does not predict decline in intelligence in healthy older adults. Neurosci Lett (2002) 0.91
Nodular disease in rheumatoid arthritis: association with cigarette smoking and HLA-DRB1/TNF gene interaction. J Rheumatol (2002) 0.90
Interferon-gamma and interleukin-4 gene polymorphisms in Caucasian idiopathic inflammatory myopathy patients in UK. Ann Rheum Dis (2007) 0.90
Have recent immunogenetic investigations increased our understanding of disease mechanisms in the idiopathic inflammatory myopathies? Curr Opin Rheumatol (2004) 0.89
Interleukin 8 gene polymorphism is associated with increased risk of nephritis in cutaneous vasculitis. J Rheumatol (2002) 0.89
Macrophage migration inhibitory factor gene polymorphism is associated with sarcoidosis in biopsy proven erythema nodosum. J Rheumatol (2002) 0.88
Analysis of candidate susceptibility genes in canine diabetes. J Hered (2007) 0.88
Transplantation of X-linked severe combined immunodeficient dogs with CD34+ bone marrow cells. Biol Blood Marrow Transplant (2002) 0.87
Autoantibodies to recombinant canine proinsulin in canine diabetic patients. Res Vet Sci (2010) 0.86
Assessment of the diagnostic accuracy of circulating natriuretic peptide concentrations to distinguish between cats with cardiac and non-cardiac causes of respiratory distress. J Vet Cardiol (2009) 0.86
Genetic control of canine leishmaniasis: genome-wide association study and genomic selection analysis. PLoS One (2012) 0.86
Hypoparathyroidism and autoimmunity in the 22q11.2 deletion syndrome. Eur J Endocrinol (2011) 0.86
MHC class II risk haplotype associated with canine chronic superficial keratitis in German Shepherd dogs. Vet Immunol Immunopathol (2010) 0.86
Isolation and characterization of pediatric canine bone marrow CD34+ cells. Vet Immunol Immunopathol (2004) 0.86
No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls. Ann Rheum Dis (2012) 0.86
Assessment of the use of RNA quality metrics for the screening of articular cartilage specimens from clinically normal dogs and dogs with osteoarthritis. Am J Vet Res (2006) 0.86
Alleles of the major histocompatibility complex play a role in the pathogenesis of pancreatic acinar atrophy in dogs. Immunogenetics (2013) 0.86
Interleukin 1beta gene polymorphism association with severe renal manifestations and renal sequelae in Henoch-Schönlein purpura. J Rheumatol (2004) 0.85
An update on the immunogenetics of idiopathic inflammatory myopathies: major histocompatibility complex and beyond. Curr Opin Rheumatol (2009) 0.85
Multisteroid LC-MS/MS assay for glucocorticoids and androgens, and its application in Addison's disease. Endocr Connect (2013) 0.85
L-2-hydroxyglutaric aciduria: characterisation of the molecular defect in a spontaneous canine model. J Med Genet (2007) 0.85
Vascular endothelial growth factor production is regulated by gene polymorphisms. Iran J Immunol (2009) 0.85
A complex rearrangement in GBE1 causes both perinatal hypoglycemic collapse and late-juvenile-onset neuromuscular degeneration in glycogen storage disease type IV of Norwegian forest cats. Mol Genet Metab (2007) 0.85
Clinicopathologic and atypical features of naturally occurring leptospirosis in dogs: 51 cases (2000-2010). J Am Vet Med Assoc (2013) 0.85
A pragmatic randomized controlled trial of thiopurine methyltransferase genotyping prior to azathioprine treatment: the TARGET study. Pharmacogenomics (2011) 0.84
DLA-DRB1, DQA1, and DQB1 alleles and haplotypes in North American Gray Wolves. J Hered (2007) 0.84
Prion protein genes in caribou from Alaska. J Wildl Dis (2007) 0.84
The keeshond defect in cardiac conotruncal development is oligogenic. Hum Genet (2005) 0.84
Genetic association study of NF-κB genes in UK Caucasian adult and juvenile onset idiopathic inflammatory myopathy. Rheumatology (Oxford) (2011) 0.84
TLR5 risk-associated haplotype for canine inflammatory bowel disease confers hyper-responsiveness to flagellin. PLoS One (2012) 0.84
Polymorphisms in canine platelet glycoproteins identify potential platelet antigens. Comp Med (2013) 0.84