Pier Luigi Martelli

Author PubWeight™ 48.20‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The implications of alternative splicing in the ENCODE protein complement. Proc Natl Acad Sci U S A 2007 3.93
2 Functional annotations improve the predictive score of human disease-related mutations in proteins. Hum Mutat 2009 3.14
3 BaCelLo: a balanced subcellular localization predictor. Bioinformatics 2006 2.14
4 PredGPI: a GPI-anchor predictor. BMC Bioinformatics 2008 1.86
5 The ectodomain of herpes simplex virus glycoprotein H contains a membrane alpha-helix with attributes of an internal fusion peptide, positionally conserved in the herpesviridae family. J Virol 2005 1.82
6 SDHA loss-of-function mutations in KIT-PDGFRA wild-type gastrointestinal stromal tumors identified by massively parallel sequencing. J Natl Cancer Inst 2011 1.53
7 A new decoding algorithm for hidden Markov models improves the prediction of the topology of all-beta membrane proteins. BMC Bioinformatics 2005 1.49
8 An initial comparative map of copy number variations in the goat (Capra hircus) genome. BMC Genomics 2010 1.18
9 WS-SNPs&GO: a web server for predicting the deleterious effect of human protein variants using functional annotation. BMC Genomics 2013 1.14
10 In silico prediction of the structure of membrane proteins: is it feasible? Brief Bioinform 2003 1.13
11 eSLDB: eukaryotic subcellular localization database. Nucleic Acids Res 2006 1.10
12 The prediction of protein subcellular localization from sequence: a shortcut to functional genome annotation. Brief Funct Genomic Proteomic 2008 1.10
13 Fishing new proteins in the twilight zone of genomes: the test case of outer membrane proteins in Escherichia coli K12, Escherichia coli O157:H7, and other Gram-negative bacteria. Protein Sci 2003 1.08
14 MaxSubSeq: an algorithm for segment-length optimization. The case study of the transmembrane spanning segments. Bioinformatics 2003 1.07
15 EX-HOM (EXome HOMozygosity): a proof of principle. Hum Hered 2011 1.06
16 A genome wide association study for backfat thickness in Italian Large White pigs highlights new regions affecting fat deposition including neuronal genes. BMC Genomics 2012 1.05
17 BAR-PLUS: the Bologna Annotation Resource Plus for functional and structural annotation of protein sequences. Nucleic Acids Res 2011 0.99
18 The bologna annotation resource: a non hierarchical method for the functional and structural annotation of protein sequences relying on a comparative large-scale genome analysis. J Proteome Res 2009 0.96
19 Improving the prediction of disulfide bonds in Eukaryotes with machine learning methods and protein subcellular localization. Bioinformatics 2011 0.94
20 Predicting protein thermostability changes from sequence upon multiple mutations. Bioinformatics 2008 0.89
21 On the effect of protein conformation diversity in discriminating among neutral and disease related single amino acid substitutions. BMC Genomics 2012 0.87
22 The pros and cons of predicting protein contact maps. Methods Mol Biol 2008 0.87
23 MemPype: a pipeline for the annotation of eukaryotic membrane proteins. Nucleic Acids Res 2011 0.87
24 MemLoci: predicting subcellular localization of membrane proteins in eukaryotes. Bioinformatics 2011 0.86
25 MIMO: an efficient tool for molecular interaction maps overlap. BMC Bioinformatics 2013 0.83
26 Prediction of disulfide connectivity in proteins with machine-learning methods and correlated mutations. BMC Bioinformatics 2013 0.82
27 Prediction of the disulfide-bonding state of cysteines in proteins at 88% accuracy. Protein Sci 2003 0.82
28 NET-GE: a novel NETwork-based Gene Enrichment for detecting biological processes associated to Mendelian diseases. BMC Genomics 2015 0.81
29 Effect of molecular confinement on internal enzyme dynamics: frequency domain fluorometry and molecular dynamics simulation studies. Biopolymers 2002 0.81
30 A low-resolution 3D model of the tetrameric alcohol dehydrogenase from Sulfolobus solfataricus. Protein Eng 2002 0.80
31 How to inherit statistically validated annotation within BAR+ protein clusters. BMC Bioinformatics 2013 0.80
32 3D structure of Sulfolobus solfataricus carboxypeptidase developed by molecular modeling is confirmed by site-directed mutagenesis and small angle X-ray scattering. Biophys J 2003 0.80
33 Pressure and temperature as tools for investigating the role of individual non-covalent interactions in enzymatic reactions Sulfolobus solfataricus carboxypeptidase as a model enzyme. Biochim Biophys Acta 2006 0.80
34 BCov: a method for predicting β-sheet topology using sparse inverse covariance estimation and integer programming. Bioinformatics 2013 0.78
35 Grammatical-Restrained Hidden Conditional Random Fields for Bioinformatics applications. Algorithms Mol Biol 2009 0.78
36 SUS-BAR: a database of pig proteins with statistically validated structural and functional annotation. Database (Oxford) 2013 0.77
37 A combined approach of mass spectrometry, molecular modeling, and site-directed mutagenesis highlights key structural features responsible for the thermostability of Sulfolobus solfataricus carboxypeptidase. Proteins 2008 0.77
38 Thinking the impossible: how to solve the protein folding problem with and without homologous structures and more. Methods Mol Biol 2007 0.77
39 The human "magnesome": detecting magnesium binding sites on human proteins. BMC Bioinformatics 2012 0.77
40 Haplotype of single nucleotide polymorphisms in exon 6 of the MZF-1 gene and Alzheimer's disease. J Alzheimers Dis 2013 0.77
41 Robust determinants of thermostability highlighted by a codon frequency index capable of discriminating thermophilic from mesophilic genomes. J Proteome Res 2007 0.77
42 The prediction of organelle-targeting peptides in eukaryotic proteins with Grammatical-Restrained Hidden Conditional Random Fields. Bioinformatics 2013 0.76
43 Mapping and annotating obesity-related genes in pig and human genomes. Protein Pept Lett 2014 0.76
44 TRAMPLE: the transmembrane protein labelling environment. Nucleic Acids Res 2005 0.75