William C Wimley

Author PubWeight™ 40.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells. Cancer Res 2006 1.94
2 Forster resonance energy transfer in liposomes: measurements of transmembrane helix dimerization in the native bilayer environment. Anal Biochem 2005 1.81
3 Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity. J Am Chem Soc 2009 1.53
4 Biomolecular engineering by combinatorial design and high-throughput screening: small, soluble peptides that permeabilize membranes. J Am Chem Soc 2008 1.46
5 Spontaneous membrane-translocating peptides by orthogonal high-throughput screening. J Am Chem Soc 2011 1.35
6 Rational combinatorial design of pore-forming beta-sheet peptides. Proc Natl Acad Sci U S A 2005 1.28
7 Transmembrane helix dimerization: beyond the search for sequence motifs. Biochim Biophys Acta 2011 1.26
8 Identification and characterization of the putative fusion peptide of the severe acute respiratory syndrome-associated coronavirus spike protein. J Virol 2005 1.16
9 Vibrational coupling, isotopic editing, and beta-sheet structure in a membrane-bound polypeptide. J Am Chem Soc 2004 1.15
10 Anticancer and chemosensitizing abilities of cycloviolacin 02 from Viola odorata and psyle cyclotides from Psychotria leptothyrsa. Biopolymers 2010 1.13
11 Beta-sheet pore-forming peptides selected from a rational combinatorial library: mechanism of pore formation in lipid vesicles and activity in biological membranes. Biochemistry 2007 1.12
12 High-throughput discovery of broad-spectrum peptide antibiotics. FASEB J 2010 1.11
13 A look at arginine in membranes. J Membr Biol 2010 1.05
14 A highly accurate statistical approach for the prediction of transmembrane beta-barrels. Bioinformatics 2010 1.01
15 The aromatic domain of the coronavirus class I viral fusion protein induces membrane permeabilization: putative role during viral entry. Biochemistry 2005 0.99
16 Release of dengue virus genome induced by a peptide inhibitor. PLoS One 2012 0.97
17 Determining the mechanism of membrane permeabilizing peptides: identification of potent, equilibrium pore-formers. Biochim Biophys Acta 2012 0.96
18 Gain-of-function analogues of the pore-forming peptide melittin selected by orthogonal high-throughput screening. J Am Chem Soc 2012 0.95
19 Viroporin potential of the lentivirus lytic peptide (LLP) domains of the HIV-1 gp41 protein. Virol J 2007 0.94
20 Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1. Virol J 2011 0.93
21 Polar residues in transmembrane helices can decrease electrophoretic mobility in polyacrylamide gels without causing helix dimerization. Biochim Biophys Acta 2009 0.92
22 Enzymatic E-colicins bind to their target receptor BtuB by presentation of a small binding epitope on a coiled-coil scaffold. J Biol Chem 2003 0.92
23 FGFR3 heterodimerization in achondroplasia, the most common form of human dwarfism. J Biol Chem 2011 0.91
24 A membrane-translocating peptide penetrates into bilayers without significant bilayer perturbations. Biophys J 2013 0.91
25 Characterization of antimicrobial peptide activity by electrochemical impedance spectroscopy. Biochim Biophys Acta 2008 0.90
26 Protein folding in membranes: insights from neutron diffraction studies of a membrane beta-sheet oligomer. Biophys J 2007 0.88
27 The electrical response of bilayers to the bee venom toxin melittin: evidence for transient bilayer permeabilization. Biochim Biophys Acta 2013 0.88
28 Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein. Virus Res 2006 0.88
29 A highly charged voltage-sensor helix spontaneously translocates across membranes. Angew Chem Int Ed Engl 2012 0.87
30 Interactions of membrane active peptides with planar supported bilayers: an impedance spectroscopy study. Langmuir 2012 0.84
31 Highly efficient macromolecule-sized poration of lipid bilayers by a synthetically evolved peptide. J Am Chem Soc 2014 0.84
32 High-throughput selection of transmembrane sequences that enhance receptor tyrosine kinase activation. J Mol Biol 2011 0.84
33 Synthetic molecular evolution of pore-forming peptides by iterative combinatorial library screening. ACS Chem Biol 2013 0.83
34 TMBB-DB: a transmembrane β-barrel proteome database. Bioinformatics 2012 0.81
35 Direct cytosolic delivery of polar cargo to cells by spontaneous membrane-translocating peptides. J Biol Chem 2013 0.81
36 The prediction and characterization of YshA, an unknown outer-membrane protein from Salmonella typhimurium. Biochim Biophys Acta 2010 0.79
37 pH Dependence of microbe sterilization by cationic antimicrobial peptides. Antimicrob Agents Chemother 2013 0.79
38 Protein folding in membranes. Biochim Biophys Acta 2012 0.78
39 Toward the de novo design of antimicrobial peptides: Lack of correlation between peptide permeabilization of lipid vesicles and antimicrobial, cytolytic, or cytotoxic activity in living cells. Biopolymers 2014 0.77
40 Structural plasticity in self-assembling transmembrane β-sheets. Biophys J 2011 0.77