Neutrophil elastase induces MUC5AC secretion via protease-activated receptor 2.

PubWeight™: 0.83‹?›

🔗 View Article (PMID 23392769)

Published in Mol Cell Biochem on February 08, 2013

Authors

Jia Zhou1, Juliy M Perelman, Victor P Kolosov, Xiangdong Zhou

Author Affiliations

1: Division of Respiratory Medicine, The Second Affiliated Hospital, Chongqing Medical University, Yuzhong District, Chongqing, China. joelle_zhou@163.com

Articles by these authors

BACE1 deficiency causes altered neuronal activity and neurodegeneration. J Neurosci (2010) 1.45

Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities. EMBO J (2007) 1.19

Cold temperature induces mucin hypersecretion from normal human bronchial epithelial cells in vitro through a transient receptor potential melastatin 8 (TRPM8)-mediated mechanism. J Allergy Clin Immunol (2011) 1.02

Roflumilast for the treatment of COPD in an Asian population: a randomized, double-blind, parallel-group study. Chest (2014) 0.99

Phase I/II study of pemetrexed with or without ABT-751 in advanced or metastatic non-small-cell lung cancer. J Clin Oncol (2011) 0.98

A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from disease. PLoS Negl Trop Dis (2013) 0.94

Interleukin-13 induces mucin 5AC production involving STAT6/SPDEF in human airway epithelial cells. Cell Commun Adhes (2011) 0.90

Nicotine reduces TNF-α expression through a α7 nAChR/MyD88/NF-ĸB pathway in HBE16 airway epithelial cells. Cell Physiol Biochem (2011) 0.90

P-selectin-mediated platelet activation promotes adhesion of non-small cell lung carcinoma cells on vascular endothelial cells under flow. Mol Med Rep (2012) 0.88

A multicenter, randomized controlled clinical study on biapenem and imipenem/cilastatin injection in the treatment of respiratory and urinary tract infections. Chemotherapy (2010) 0.87

Mapping of interaction domains mediating binding between BACE1 and RTN/Nogo proteins. J Mol Biol (2006) 0.85

Regulation of cigarette smoke-mediated mucin expression by hypoxia-inducible factor-1α via epidermal growth factor receptor-mediated signaling pathways. J Appl Toxicol (2011) 0.85

Identification of CD90 as a marker for lung cancer stem cells in A549 and H446 cell lines. Oncol Rep (2013) 0.85

Regulator of G-protein signaling 2 inhibits acid-induced mucin5AC hypersecretion in human airway epithelial cells. Respir Physiol Neurobiol (2012) 0.84

Bone marrow-derived cells contribute to NDEA-induced lung squamous cell carcinoma. Tumour Biol (2012) 0.83

Preventing formation of reticulon 3 immunoreactive dystrophic neurites improves cognitive function in mice. J Neurosci (2013) 0.82

The effect of quercetin on human neutrophil elastase-induced mucin5AC expression in human airway epithelial cells. Int Immunopharmacol (2012) 0.82

Human airway trypsin-like protease induces mucin5AC hypersecretion via a protease-activated receptor 2-mediated pathway in human airway epithelial cells. Arch Biochem Biophys (2013) 0.81

Oxidative stress mediates the disruption of airway epithelial tight junctions through a TRPM2-PLCγ1-PKCα signaling pathway. Int J Mol Sci (2013) 0.81

[Effect of exercise combined with encouragement on quality of life of patients with chronic obstructive pulmonary disease]. Nan Fang Yi Ke Da Xue Xue Bao (2013) 0.80

MiR-146a negatively regulates neutrophil elastase-induced MUC5AC secretion from 16HBE human bronchial epithelial cells. Mol Cell Biochem (2011) 0.80

Flagellin/TLR5 responses induce mucus hypersecretion by activating EGFR via an epithelial cell signaling cascades. Exp Cell Res (2011) 0.80

Ezrin/Exocyst complex regulates mucin 5AC secretion induced by neutrophil elastase in human airway epithelial cells. Cell Physiol Biochem (2015) 0.80

Regulation of cigarette smoke-induced mucin expression by neuregulin1β/ErbB3 signalling in human airway epithelial cells. Basic Clin Pharmacol Toxicol (2011) 0.79

Nicotine suppresses inflammatory factors in HBE16 airway epithelial cells after exposure to cigarette smoke extract and lipopolysaccharide. Transl Res (2010) 0.79

[Effect of exercise on the quality of life and pulmonary function in patients with chronic obstructive pulmonary disease]. Zhong Nan Da Xue Xue Bao Yi Xue Ban (2011) 0.79

Changes in gamma-secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1. Mol Neurodegener (2008) 0.79

Expression of SHP2 and related markers in non-small cell lung cancer: a tissue microarray study of 80 cases. Appl Immunohistochem Mol Morphol (2013) 0.79

Transient receptor potential vanilloid 1 receptors mediate acid-induced mucin secretion via Ca2+ influx in human airway epithelial cells. J Biochem Mol Toxicol (2012) 0.78

[The study of PI3K/AKT pathway in lung cancer metastasis and drug resistance]. Zhongguo Fei Ai Za Zhi (2011) 0.78

[CA916798 gene participates in cisplatin resistance of human lung adenocarcinoma A549 cells through PI3K/AKT/mTOR pathway]. Nan Fang Yi Ke Da Xue Xue Bao (2012) 0.78

Chronic mechanical stress induces mucin 5AC expression in human bronchial epithelial cells through ERK dependent pathways. Mol Biol Rep (2011) 0.78

Differential effects of mesenchymal stem cells on a heterogeneous cell population within lung cancer cell lines. Mol Cell Biochem (2013) 0.78

The chitinase-like protein YKL-40 increases mucin5AC production in human bronchial epithelial cells. Exp Cell Res (2013) 0.78

Rhythmic pressure waves induce mucin5AC expression via an EGFR-mediated signaling pathway in human airway epithelial cells. DNA Cell Biol (2013) 0.78

Regulation of PMA-induced MUC5AC expression by heparin in human bronchial epithelial cells. Mol Cell Biochem (2011) 0.78

Cortactin mediates elevated shear stress-induced mucin hypersecretion via actin polymerization in human airway epithelial cells. Int J Biochem Cell Biol (2013) 0.77

Activated platelets interact with lung cancer cells through P-selectin glycoprotein ligand-1. Pathol Oncol Res (2012) 0.77

Annexin II mediates the neutrophil elastase-stimulated exocytosis of mucin 5ac. Mol Med Rep (2013) 0.77

The expression and pharmacological characterization of nicotinic acetylcholine receptor subunits in HBE16 airway epithelial cells. Cell Biochem Biophys (2012) 0.77

Scutellarin attenuates human-neutrophil-elastase-induced mucus production by inhibiting the PKC-ERK signaling pathway in vitro and in vivo. Am J Chin Med (2011) 0.77

Depolarization promotes survival of ciliary ganglion neurons by BDNF-dependent and -independent mechanisms. Dev Biol (2006) 0.77

Regulation of particulate matter-induced mucin secretion by transient receptor potential vanilloid 1 receptors. Inflammation (2012) 0.77

The pathophysiological mechanisms underlying mucus hypersecretion induced by cold temperatures in cigarette smoke-exposed rats. Int J Mol Med (2013) 0.77

Synthesis of well-defined polymers grafted onto fumed silica by chain exchange reaction and highly pure block copolymers thereby. Chem Commun (Camb) (2010) 0.76

Construction of luciferase reporter gene vector for human MUC5AC gene promoter and analysis of its transcriptional activity. Zhong Nan Da Xue Xue Bao Yi Xue Ban (2010) 0.76

The role of recombinant human elafin in the resistance of A549 cells against Pseudomonas aeruginosa biofilm. Respiration (2009) 0.76

The inhibition of aldose reductase on mucus production induced by interleukin-13 in the human bronchial epithelial cells. Int Immunopharmacol (2012) 0.76

[Effect of osmotic response element binding protein on mucus secretion with hypertonicity in human airway epithelial cells]. Zhonghua Yi Xue Za Zhi (2011) 0.76

Hypoxia induces mucin expression and secretion in human bronchial epithelial cells. Transl Res (2012) 0.76

Role of hyaluronan and CD44 in reactive oxygen species-induced mucus hypersecretion. Mol Cell Biochem (2011) 0.76

[Expression and its clinical significance of SHP2 in non-small cell lung cancer]. Zhongguo Fei Ai Za Zhi (2010) 0.76

Secretoneurin induces airway mucus hypersecretion by enhancing the binding of EGF to NRP1. Cell Physiol Biochem (2014) 0.76

Triiodothyronine represses MUC5AC expression by antagonizing Sp1 binding to its promoter in human bronchial epithelial HBE16 cells. J Biomed Biotechnol (2012) 0.76

Theaflavins extracted from black tea inhibit airway mucous hypersecretion induced by cigarette smoke in rats. Inflammation (2012) 0.75