Published in Stem Cell Res on January 14, 2013
Regulation of immune responses by extracellular vesicles. Nat Rev Immunol (2014) 3.24
Exosomes as critical agents of cardiac regeneration triggered by cell therapy. Stem Cell Reports (2014) 1.90
Sorting it out: regulation of exosome loading. Semin Cancer Biol (2014) 1.54
Embryonic stem cell-derived exosomes promote endogenous repair mechanisms and enhance cardiac function following myocardial infarction. Circ Res (2015) 1.46
Cell based therapies for ischemic stroke: from basic science to bedside. Prog Neurobiol (2013) 1.39
Therapeutic applications of extracellular vesicles: clinical promise and open questions. Annu Rev Pharmacol Toxicol (2014) 1.29
FedExosomes: Engineering Therapeutic Biological Nanoparticles that Truly Deliver. Pharmaceuticals (Basel) (2013) 1.24
Extracellular vesicles: potential roles in regenerative medicine. Front Immunol (2014) 1.17
Exosomes and exosomal miRNAs in cardiovascular protection and repair. Vascul Pharmacol (2015) 1.16
A review of therapeutic effects of mesenchymal stem cell secretions and induction of secretory modification by different culture methods. J Transl Med (2014) 1.10
Role of extracellular RNA-carrying vesicles in cell differentiation and reprogramming. Stem Cell Res Ther (2015) 1.09
Extracellular vesicles including exosomes are mediators of signal transduction: are they protective or pathogenic? Proteomics (2014) 1.09
Pathologic function and therapeutic potential of exosomes in cardiovascular disease. Biochim Biophys Acta (2014) 1.06
Exosomes secreted from GATA-4 overexpressing mesenchymal stem cells serve as a reservoir of anti-apoptotic microRNAs for cardioprotection. Int J Cardiol (2014) 1.05
Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications. Mol Ther (2015) 1.02
Exosomes secreted by human-induced pluripotent stem cell-derived mesenchymal stem cells attenuate limb ischemia by promoting angiogenesis in mice. Stem Cell Res Ther (2015) 1.01
Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Relieve Acute Myocardial Ischemic Injury. Stem Cells Int (2015) 1.01
The current landscape of the mesenchymal stromal cell secretome: A new paradigm for cell-free regeneration. Cytotherapy (2015) 1.00
Extracellular Vesicles: Satellites of Information Transfer in Cancer and Stem Cell Biology. Dev Cell (2016) 0.99
Therapeutic Effects of Human Mesenchymal Stem Cell-derived Microvesicles in Severe Pneumonia in Mice. Am J Respir Crit Care Med (2015) 0.97
A New Paradigm in Cardiac Regeneration: The Mesenchymal Stem Cell Secretome. Stem Cells Int (2015) 0.96
Extracellular vesicles as therapeutic tools in cardiovascular diseases. Front Immunol (2014) 0.95
Cell-based therapy for acute organ injury: preclinical evidence and ongoing clinical trials using mesenchymal stem cells. Anesthesiology (2014) 0.94
Immunotherapeutic potential of extracellular vesicles. Front Immunol (2014) 0.94
From bench to bedside: use of human adipose-derived stem cells. Stem Cells Cloning (2015) 0.91
Molecular Characterization of Reactive Oxygen Species in Myocardial Ischemia-Reperfusion Injury. Biomed Res Int (2015) 0.89
Mechanisms of mesenchymal stem/stromal cell function. Stem Cell Res Ther (2016) 0.88
Extracellular Vesicles in Heart Disease: Excitement for the Future ? Exosomes Microvesicles (2014) 0.87
Exosomes in mesenchymal stem cells, a new therapeutic strategy for cardiovascular diseases? Int J Biol Sci (2015) 0.87
The role of antioxidation and immunomodulation in postnatal multipotent stem cell-mediated cardiac repair. Int J Mol Sci (2013) 0.87
Using exosomes, naturally-equipped nanocarriers, for drug delivery. J Control Release (2015) 0.86
Potential Therapies by Stem Cell-Derived Exosomes in CNS Diseases: Focusing on the Neurogenic Niche. Stem Cells Int (2016) 0.85
Extracellular Vesicles: Evolving Factors in Stem Cell Biology. Stem Cells Int (2015) 0.84
More Than Tiny Sacks: Stem Cell Exosomes as Cell-Free Modality for Cardiac Repair. Circ Res (2016) 0.84
Focus on Extracellular Vesicles: Physiological Role and Signalling Properties of Extracellular Membrane Vesicles. Int J Mol Sci (2016) 0.84
Extracellular vesicles in coronary artery disease. Nat Rev Cardiol (2017) 0.84
Mesenchymal Stem Cell-Based Therapy for Kidney Disease: A Review of Clinical Evidence. Stem Cells Int (2016) 0.83
Ischemic postconditioning influences electron transport chain protein turnover in Langendorff-perfused rat hearts. PeerJ (2016) 0.83
Stem cell-based therapies for the newborn lung and brain: Possibilities and challenges. Semin Perinatol (2016) 0.83
Bone Marrow Mesenchymal Stem Cells (BM-MSCs) Improve Heart Function in Swine Myocardial Infarction Model through Paracrine Effects. Sci Rep (2016) 0.83
Regulation of chronic inflammatory and immune processes by extracellular vesicles. J Clin Invest (2016) 0.82
Stem cell-derived exosomes: roles in stromal remodeling, tumor progression, and cancer immunotherapy. Chin J Cancer (2015) 0.82
Exosomes for Intramyocardial Intercellular Communication. Stem Cells Int (2015) 0.82
MSCs-Derived Exosomes: Cell-Secreted Nanovesicles with Regenerative Potential. Front Pharmacol (2016) 0.82
How to Improve the Survival of Transplanted Mesenchymal Stem Cell in Ischemic Heart? Stem Cells Int (2015) 0.81
Exosomes: a potential key target in cardio-renal syndrome. Front Immunol (2014) 0.81
Exosomes: Fundamental Biology and Roles in Cardiovascular Physiology. Annu Rev Physiol (2015) 0.80
Extracellular vesicles in cardiovascular disease: are they Jedi or Sith? J Physiol (2016) 0.80
In vivo tracking of human adipose-derived stem cells labeled with ferumoxytol in rats with middle cerebral artery occlusion by magnetic resonance imaging. Neural Regen Res (2015) 0.80
Cardiovascular Regenerative Technologies: Update and Future Outlook. Transfus Med Hemother (2016) 0.80
Exosomes: The Messengers of Health and Disease. Curr Neuropharmacol (2016) 0.80
Inhibition of Myocardial Ischemia/Reperfusion Injury by Exosomes Secreted from Mesenchymal Stem Cells. Stem Cells Int (2016) 0.80
Advances in bone marrow stem cell therapy for retinal dysfunction. Prog Retin Eye Res (2016) 0.79
Mesenchymal stem cell derived secretome and extracellular vesicles for acute lung injury and other inflammatory lung diseases. Expert Opin Biol Ther (2016) 0.79
Circulating exosomes potentiate tumor malignant properties in a mouse model of chronic sleep fragmentation. Oncotarget (2016) 0.79
Up-regulation of microRNA-135a protects against myocardial ischemia/reperfusion injury by decreasing TXNIP expression in diabetic mice. Am J Transl Res (2015) 0.79
The Regenerative Role of the Fetal and Adult Stem Cell Secretome. J Clin Med (2013) 0.79
Molecular signatures of mesenchymal stem cell-derived extracellular vesicle-mediated tissue repair. Stem Cell Res Ther (2015) 0.78
RNA in extracellular vesicles. Wiley Interdiscip Rev RNA (2017) 0.77
Stem cell-derived exosomes as a therapeutic tool for cardiovascular disease. World J Stem Cells (2016) 0.77
Exosomes Mediate the Intercellular Communication after Myocardial Infarction. Int J Med Sci (2016) 0.77
Exosome and its roles in cardiovascular diseases. Heart Fail Rev (2015) 0.77
Methylophiopogonanone A suppresses ischemia/reperfusion-induced myocardial apoptosis in mice via activating PI3K/Akt/eNOS signaling pathway. Acta Pharmacol Sin (2016) 0.77
New strategies for improving stem cell therapy in ischemic heart disease. Heart Fail Rev (2016) 0.77
Control of bone development by P2X and P2Y receptors expressed in mesenchymal and hematopoietic cells. Gene (2015) 0.77
Functions of Cancer-Derived Extracellular Vesicles in Immunosuppression. Arch Immunol Ther Exp (Warsz) (2017) 0.76
Acellular approaches for regenerative medicine: on the verge of clinical trials with extracellular membrane vesicles? Stem Cell Res Ther (2015) 0.76
Adipose-Derived Stem Cells Induce Angiogenesis via Microvesicle Transport of miRNA-31. Stem Cells Transl Med (2016) 0.76
Local injection of mesenchymal stem cells protects testicular torsion-induced germ cell injury. Stem Cell Res Ther (2015) 0.76
Re-Engineering Extracellular Vesicles as Smart Nanoscale Therapeutics. ACS Nano (2017) 0.76
Emerging applications of exosomes in cancer therapeutics and diagnostics. Bioeng Transl Med (2017) 0.75
Electrical stimulation to optimize cardioprotective exosomes from cardiac stem cells. Med Hypotheses (2016) 0.75
New Delivery Systems of Stem Cells for Vascular Regeneration in Ischemia. Front Cardiovasc Med (2017) 0.75
Platelet-derived microvesicles are involved in cardio-protective effects of remote preconditioning. Int J Clin Exp Pathol (2015) 0.75
Exosomes and Cardiovascular Protection. Cardiovasc Drugs Ther (2016) 0.75
Evidence for Transfer of Membranes from Mesenchymal Stem Cells to HL-1 Cardiac Cells. Stem Cells Int (2014) 0.75
Mesenchymal Stem Cell Derived Exosomes: A New Hope for the Treatment of Cardiovascular Disease? Zhonghua Minguo Xin Zang Xue Hui Za Zhi (2014) 0.75
Stromal Progenitor Cells in Mitigation of Non-Hematopoietic Radiation Injuries. Curr Pathobiol Rep (2016) 0.75
Exosomes: What Do We Love So Much About Them? Circ Res (2016) 0.75
Overexpression of Heme Oxygenase-1 in Mesenchymal Stem Cells Augments Their Protection on Retinal Cells In Vitro and Attenuates Retinal Ischemia/Reperfusion Injury In Vivo against Oxidative Stress. Stem Cells Int (2017) 0.75
Adaptive inflammatory microenvironment for cell-based regeneration in ischemic cardiovascular disease. Organogenesis (2013) 0.75
Modulation of the Mesenchymal Stem Cell Secretome Using Computer-Controlled Bioreactors: Impact on Neuronal Cell Proliferation, Survival and Differentiation. Sci Rep (2016) 0.75
Extracellular Vesicle-functionalized Decalcified Bone Matrix Scaffolds with Enhanced Pro-angiogenic and Pro-bone Regeneration Activities. Sci Rep (2017) 0.75
Exosomes Generated From iPSC-Derivatives: New Direction for Stem Cell Therapy in Human Heart Diseases. Circ Res (2017) 0.75
Mesenchymal Stem Cells as a Prospective Therapy for the Diabetic Foot. Stem Cells Int (2016) 0.75
Stem Cells and Cardiac Repair. Stem Cells Int (2015) 0.75
Mesenchymal Stem Cell-Derived Exosomes: New Opportunity in Cell-Free Therapy. Adv Pharm Bull (2016) 0.75
Stem Cell Extracellular Vesicles: Extended Messages of Regeneration. Annu Rev Pharmacol Toxicol (2016) 0.75
Extracellular vesicles: small bricks for tissue repair/regeneration. Ann Transl Med (2017) 0.75
Biomimetic and synthetic interfaces to tune immune responses. Biointerphases (2015) 0.75
Exosomes Secreted from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Osteonecrosis of the Femoral Head by Promoting Angiogenesis. Int J Biol Sci (2017) 0.75
Microvesicles Derived From Human Mesenchymal Stem Cells Restore Alveolar Fluid Clearance in Human Lungs Rejected for Transplantation. Am J Transplant (2015) 0.75
Therapeutic potential of human adipose-derived stem cells (ADSCs) from cancer patients: a pilot study. PLoS One (2014) 0.75
Impact of cell culture parameters on production and vascularization bioactivity of mesenchymal stem cell-derived extracellular vesicles. Bioeng Transl Med (2017) 0.75
Exploring pericyte and cardiac stem cell secretome unveils new tactics for drug discovery. Pharmacol Ther (2016) 0.75
Exosomes secreted by stem cells from human exfoliated deciduous teeth contribute to functional recovery after traumatic brain injury by shifting microglia M1/M2 polarization in rats. Stem Cell Res Ther (2017) 0.75
Exosomes in Cardiovascular Medicine. Cardiol Ther (2017) 0.75
From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation (2003) 8.61
Diagnostic accuracy of 64-slice computed tomography coronary angiography: a prospective, multicenter, multivendor study. J Am Coll Cardiol (2008) 7.56
Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells. Cell Stem Cell (2007) 7.05
MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure. Circulation (2007) 6.41
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87
Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury. Stem Cell Res (2010) 4.06
From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II. Circulation (2003) 3.94
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. PLoS Biol (2012) 3.18
Human embryonic stem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction. Stem Cell Res (2007) 3.04
Exenatide reduces infarct size and improves cardiac function in a porcine model of ischemia and reperfusion injury. J Am Coll Cardiol (2009) 2.94
In vivo cell seeding with anti-CD34 antibodies successfully accelerates endothelialization but stimulates intimal hyperplasia in porcine arteriovenous expanded polytetrafluoroethylene grafts. Circulation (2005) 2.69
Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction. Circ Res (2007) 2.69
Genetic variations of KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 in drug-induced long QT syndrome patients. J Mol Med (Berl) (2004) 2.68
Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs. Nucleic Acids Res (2009) 2.66
Cognitive outcomes 7.5 years after angioplasty compared with off-pump coronary bypass surgery. Ann Thorac Surg (2013) 2.64
Peri-coronary epicardial adipose tissue is related to cardiovascular risk factors and coronary artery calcification in post-menopausal women. Eur Heart J (2007) 2.60
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
Human embryonic stem cell-derived cardiomyocytes and cardiac repair in rodents. Circ Res (2008) 2.31
Incidence and predictors of short- and long-term complications in pacemaker therapy: the FOLLOWPACE study. Heart Rhythm (2011) 2.29
Targeted inhibition of p38 mitogen-activated protein kinase antagonizes cardiac injury and cell death following ischemia-reperfusion in vivo. J Biol Chem (2004) 2.24
MicroRNA-1 and -499 regulate differentiation and proliferation in human-derived cardiomyocyte progenitor cells. Arterioscler Thromb Vasc Biol (2010) 2.23
Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice. Heart Rhythm (2011) 2.21
Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. J Am Coll Cardiol (2013) 2.18
Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis. J Exp Med (2009) 2.17
Plasmin cleavage of von Willebrand factor as an emergency bypass for ADAMTS13 deficiency in thrombotic microangiopathy. Circulation (2014) 2.16
Human cardiomyocyte progenitor cells differentiate into functional mature cardiomyocytes: an in vitro model for studying human cardiac physiology and pathophysiology. Nat Protoc (2009) 2.16
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet (2010) 2.15
Automated 3D analysis of pre-procedural MDCT to predict annulus plane angulation and C-arm positioning: benefit on procedural outcome in patients referred for TAVR. JACC Cardiovasc Imaging (2013) 2.10
The severe cardiorenal syndrome: 'Guyton revisited'. Eur Heart J (2004) 2.09
Activation delay and VT parameters in arrhythmogenic right ventricular dysplasia/cardiomyopathy: toward improvement of diagnostic ECG criteria. J Cardiovasc Electrophysiol (2008) 2.09
Characterizing vulnerable plaque features with intravascular elastography. Circulation (2003) 2.07
TGF-beta1 induces efficient differentiation of human cardiomyocyte progenitor cells into functional cardiomyocytes in vitro. Stem Cell Res (2008) 1.98
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. Mol Cell Proteomics (2010) 1.97
Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium. Stem Cell Res (2008) 1.97
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet (2012) 1.96
Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease. Regen Med (2011) 1.95
Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibody. Circulation (2009) 1.94
Clinical Presentation, Long-Term Follow-Up, and Outcomes of 1001 Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patients and Family Members. Circ Cardiovasc Genet (2015) 1.94
Aldosterone, mortality, and acute ischaemic events in coronary artery disease patients outside the setting of acute myocardial infarction or heart failure. Eur Heart J (2011) 1.93
β-radiation reduces the reactivity of extracellular matrix proteins in intravascular brachytherapy (IVBT), resulting in decreased platelet adhesion. Int J Cardiol (2010) 1.91
Echocardiographic quantification of myocardial function using tissue deformation imaging, a guide to image acquisition and analysis using tissue Doppler and speckle tracking. Cardiovasc Ultrasound (2007) 1.90
Cardiomyocyte cell cycle activation improves cardiac function after myocardial infarction. Cardiovasc Res (2007) 1.90
Human relevance of pre-clinical studies in stem cell therapy: systematic review and meta-analysis of large animal models of ischaemic heart disease. Cardiovasc Res (2011) 1.85
Quantification of epicardial and peri-coronary fat using cardiac computed tomography; reproducibility and relation with obesity and metabolic syndrome in patients suspected of coronary artery disease. Atherosclerosis (2007) 1.80
MEF2 activates a genetic program promoting chamber dilation and contractile dysfunction in calcineurin-induced heart failure. Circulation (2006) 1.80
Genetic inflammatory factors predict restenosis after percutaneous coronary interventions. Circulation (2005) 1.78
Targeted deletion of nuclear factor kappaB p50 enhances cardiac remodeling and dysfunction following myocardial infarction. Circ Res (2009) 1.76
Coronary collaterals improve prognosis in patients with ischemic heart disease. Int J Cardiol (2008) 1.74
Relation of epicardial and pericoronary fat to coronary atherosclerosis and coronary artery calcium in patients undergoing coronary angiography. Am J Cardiol (2008) 1.72
Myocyte apoptosis in heart failure. Cardiovasc Res (2005) 1.71
Cardiomyocyte-restricted deletion of connexin43 during mouse development. J Mol Cell Cardiol (2006) 1.70
MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo. Circulation (2004) 1.69
Role of apoptosis in reperfusion injury. Cardiovasc Res (2004) 1.69
Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype. Eur Heart J (2013) 1.67
Paraoxonase variants relate to 10-year risk in coronary artery disease: impact of a high-density lipoprotein-bound antioxidant in secondary prevention. J Am Coll Cardiol (2009) 1.65
Circulating growth differentiation factor-15 correlates with myocardial fibrosis in patients with non-ischaemic dilated cardiomyopathy and decreases rapidly after left ventricular assist device support. Eur J Heart Fail (2012) 1.64
Treatment with OPN-305, a humanized anti-Toll-Like receptor-2 antibody, reduces myocardial ischemia/reperfusion injury in pigs. Circ Cardiovasc Interv (2012) 1.62
Composition of carotid atherosclerotic plaque is associated with cardiovascular outcome: a prognostic study. Circulation (2010) 1.61
Cyclooxygenase-2 inhibition increases mortality, enhances left ventricular remodeling, and impairs systolic function after myocardial infarction in the pig. Circulation (2007) 1.61
In vivo evidence for a role of toll-like receptor 4 in the development of intimal lesions. Circulation (2002) 1.61
Association of human connexin40 gene polymorphisms with atrial vulnerability as a risk factor for idiopathic atrial fibrillation. Circ Res (2004) 1.59
Localized measurement of optical attenuation coefficients of atherosclerotic plaque constituents by quantitative optical coherence tomography. IEEE Trans Med Imaging (2005) 1.59
Intracoronary infusion of autologous mononuclear bone marrow cells in patients with acute myocardial infarction treated with primary PCI: Pilot study of the multicenter HEBE trial. Catheter Cardiovasc Interv (2008) 1.58
Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium. Cardiovasc Res (2009) 1.52
Response to cardiac resynchronization therapy: is it time to expand the criteria? Pacing Clin Electrophysiol (2009) 1.52
Early statin treatment prior to primary PCI for acute myocardial infarction: REPERATOR, a randomized placebo-controlled pilot trial. Catheter Cardiovasc Interv (2012) 1.51
Elucidating the secretion proteome of human embryonic stem cell-derived mesenchymal stem cells. Mol Cell Proteomics (2007) 1.51
Toll like receptor 4 in atherosclerosis and plaque destabilization. Atherosclerosis (2009) 1.51
Cardiac resynchronization therapy beyond nominal settings: who needs individual programming of the atrioventricular and interventricular delay? Europace (2012) 1.51
Clinical prediction rule to estimate the absolute 3-year risk of major cardiovascular events after carotid endarterectomy. Stroke (2012) 1.50
Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction. Stem Cell Res (2011) 1.50
Identification of atherosclerotic plaque components with intravascular ultrasound elastography in vivo: a Yucatan pig study. Circulation (2002) 1.49
Forkhead box protein P1 as a downstream target of transforming growth factor-β induces collagen synthesis and correlates with a more stable plaque phenotype. Atherosclerosis (2011) 1.48
Innate immune signaling in cardiac ischemia. Nat Rev Cardiol (2011) 1.48