PubRank

C Pedone

Author PubWeight™ 84.00‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Hypotension and cognitive impairment: Selective association in patients with heart failure. Neurology 2001 3.33
2 Body mass index and mortality among hospitalized patients. Arch Intern Med 2000 2.29
3 Trends in antihypertensive drugs in the elderly: the decline of thiazides. J Hum Hypertens 2001 1.99
4 The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus. J Mol Biol 2001 1.58
5 Age-related pharmacokinetic and pharmacodynamic changes and related risk of adverse drug reactions. Curr Med Chem 2010 1.28
6 A snapshot of a transition state analogue of a novel thermophilic esterase belonging to the subfamily of mammalian hormone-sensitive lipase. J Mol Biol 2000 1.25
7 Covalently immobilized RGD gradient on PEG hydrogel scaffold influences cell migration parameters. Acta Biomater 2010 1.19
8 Long polypeptide 3(10)-helices at atomic resolution. Proc Natl Acad Sci U S A 1986 1.18
9 Prevention of dementia: Syst-Eur trial. Lancet 1999 1.11
10 Cognitive dysfunction as a major determinant of disability in patients with heart failure: results from a multicentre survey. On behalf of the GIFA (SIGG-ONLUS) Investigators. J Neurol Neurosurg Psychiatry 2001 1.08
11 Cerebral hemodynamics and cognitive performance in patients with asymptomatic carotid stenosis. Neurology 2009 1.06
12 Peptaibol antibiotics: a study on the helical structure of the 2-9 sequence of emerimicins III and IV. Proc Natl Acad Sci U S A 1982 1.03
13 Milk fermented with yogurt cultures and Lactobacillus casei compared with yogurt and gelled milk: influence on intestinal microflora in healthy infants. Am J Clin Nutr 1998 1.01
14 Study should have reported more data about associated diseases. BMJ 2001 0.97
15 Deletion mapping of the long arm of chromosome 10 in glioblastoma multiforme. Genes Chromosomes Cancer 1993 0.96
16 Distinct mechanisms of forskolin-stimulated cyclic AMP accumulation and forskolin-potentiated hormone responses in C6-2B cells. Mol Pharmacol 1984 0.92
17 Validation of FEV6 in the elderly: correlates of performance and repeatability. Thorax 2007 0.92
18 Dose-related impact of alcohol consumption on cognitive function in advanced age: results of a multicenter survey. Alcohol Clin Exp Res 2001 0.91
19 Flexibility of supposed "rigid" molecules: substituted 2,5-piperazinediones (diketopiperazines). Proc Natl Acad Sci U S A 1969 0.90
20 Conformations of bioactive peptides: cyclolinopeptide A. Biopolymers 1987 0.90
21 A double-stranded beta-helix with antiparallel chains in a crystalline oligo-L-D-peptide. Nature 1979 0.90
22 The neuroblastoma tumour-suppressor TrkAI and its oncogenic alternative TrkAIII splice variant exhibit geldanamycin-sensitive interactions with Hsp90 in human neuroblastoma cells. Oncogene 2009 0.89
23 Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites. Eur J Biochem 2001 0.89
24 Treatment of osteoporosis among older adults discharged from hospital in Italy. Eur J Clin Pharmacol 2001 0.89
25 Pharmacosurveillance in hospitalized patients in Italy. Study design of the 'Gruppo Italiano di Farmacovigilanza nell'Anziano' (GIFA). Pharmacol Res 1999 0.88
26 Conformational aspects of polypeptide structure. XLI. Crystal structure of S-thiazolidine-4-carboxylic acid and helical structure of poly((S)-thiazolidine-4-carboxylic acid). Biopolymers 1972 0.87
27 Predicting length of stay of older patients with exacerbated chronic obstructive pulmonary disease. Aging (Milano) 2001 0.86
28 Structure-toxicity relationships in the amatoxin series. Synthesis of S-deoxy[gamma(R)-hydroxy-Ile3]-amaninamide, its crystal and molecular structure and inhibitory efficiency. Int J Pept Protein Res 1989 0.86
29 Structural versatility of peptides containing C alpha, alpha-dialkylated glycines. An X-ray diffraction study of six 1-aminocyclopropane-1-carboxylic acid rich peptides. Int J Biol Macromol 1989 0.86
30 Factors associated with cognitive impairment among older Italian inpatients. Gruppo Italiano di Farmacovigilanza nell'Anziano (G.I.F.A.). J Am Geriatr Soc 1997 0.86
31 Forskolin-stimulated cyclic AMP accumulation mediates protein synthesis-dependent refractoriness in C6-2B rat glioma cells. J Cyclic Nucleotide Protein Phosphor Res 1983 0.85
32 Maintenance of whole cell isoproterenol and forskolin responsiveness in adenylate cyclase of permeabilized cells. J Cyclic Nucleotide Protein Phosphor Res 1986 0.84
33 Hip fracture in nursing homes: an Italian study on prevalence, latency, risk factors, and impact on mobility. Calcif Tissue Int 2001 0.84
34 In vitro and in vivo characterization of Indium-111 and Technetium-99m labeled CCK-8 derivatives for CCK-B receptor imaging. Cancer Biother Radiopharm 2004 0.84
35 Noncoded residues as building blocks in the design of specific secondary structures: symmetrically disubstituted glycines and beta-alanine. Biopolymers 1993 0.84
36 Common alternative gene alterations in adult malignant astrocytomas, but not in childhood primitive neuroectodermal tumors: P 16ink4 homozygous deletions and CDK4 gene amplifications. J Neurosurg 1996 0.83
37 Solid state structural analysis of the cyclooctapeptide cyclo- (Pro1-Pro-Phe-Phe-Ac6c-Ile-D-Ala-Val8). Biopolymers 2000 0.83
38 MEN 10,627, a novel polycyclic peptide antagonist of tachykinin NK2 receptors. J Pharmacol Exp Ther 1994 0.82
39 Immunocytochemical mapping of the phosphatase and tensin homolog (PTEN/MMAC1) tumor suppressor protein in human gliomas. Neuro Oncol 2000 0.82
40 Effect of local and remote ischemic preconditioning on endothelial function in young people and healthy or hypertensive elderly people. Atherosclerosis 2011 0.82
41 Conformational versatility of the N alpha-acylated tripeptide amide tail of oxytocin. Synthesis and crystallographic characterization of three C2 alpha-backbone modified, conformationally restricted analogues. Int J Pept Protein Res 1993 0.82
42 Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression. Curr Drug Targets 2004 0.82
43 Selective reduction of forskolin-stimulated cyclic AMP accumulation by inhibitors of protein synthesis. Science 1983 0.82
44 Regularly alternating L,D-peptides. III. Hexacyclic peptides from valine or phenylalanine. Biopolymers 1989 0.82
45 Colistin bladder instillation, an alternative way of treating multi-resistant Acinetobacter urinary tract infection: a case series and review of literature. Infection 2013 0.81
46 Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex. Protein Sci 1998 0.81
47 Effects of clinical and laboratory variables at admission and of in-hospital treatment with cardiovascular drugs on short term prognosis of ischemic stroke. The GIFA study. Nutr Metab Cardiovasc Dis 2012 0.81
48 Regularly alternating L,D-peptides. II. The double-stranded right-handed antiparallel beta-helix in the structure of t-Boc-(L-Phe-D-Phe)4-OMe. Biopolymers 1989 0.81
49 Pattern of metabolism and composition of the fecal microflora in infants 10 to 18 months old from day care centers. J Pediatr Gastroenterol Nutr 1997 0.81
50 Antimicrobial peptides from plants: stabilization of the γ core of a tomato defensin by intramolecular disulfide bond. J Pept Sci 2013 0.81
51 Long term outcome in patients with silent versus symptomatic ischaemia during dobutamine stress echocardiography. Heart 2005 0.81
52 Health care for older people in Italy: The U.L.I.S.S.E. Project (Un link informatico sui servizi sanitari esistenti per l'anziano - a computerized network on health care services for older people). J Nutr Health Aging 2010 0.80
53 Rational design of true hirudin mimetics: synthesis and characterization of multisite-directed alpha-thrombin inhibitors. J Med Chem 1996 0.80
54 Construct validity of the 15-item geriatric depression scale in older medical inpatients. J Geriatr Psychiatry Neurol 2003 0.80
55 A crystal structure with features of an antiparallel alpha-pleated sheet. Biopolymers 1994 0.80
56 Age and severe adverse drug reactions caused by nifedipine and verapamil. Gruppo Italiano di Farmacovigilanza nell' Anziano (GIFA). J Clin Epidemiol 1996 0.79
57 Long, chiral polypeptide 3(10)-helices at atomic resolution. J Biomol Struct Dyn 1988 0.79
58 Molecular structure of peptaibol antibiotics: solution conformation and crystal structure of the octapeptide corresponding to the 2-9 sequence of emerimicins III and IV. J Biomol Struct Dyn 1985 0.79
59 The longest, regular polypeptide 3(10) helix at atomic resolution. J Mol Biol 1990 0.79
60 Use of calcium antagonists and hemoglobin loss in hospitalized elderly patients: a cohort study. Gruppo Italiano di Farmacoepidemiologia nell'Anziano (GIFA) investigators. Clin Pharmacol Ther 2000 0.79
61 Lipid-lowering therapy in patients with coronary artery disease: sex or age bias? Arch Intern Med 2000 0.78
62 Computational procedures to explain the different biological activity of DNA/DNA, DNA/PNA and PNA/PNA hybrid molecules mimicking NF-kappaB binding sites. J Biomol Struct Dyn 2000 0.78
63 Synthesis and solution characterization of a porphyrin-CCK8 conjugate. J Pept Sci 2001 0.78
64 Molecular dynamics simulation in vacuo and in solution of [Aib5,6-D-Ala8] cyclolinopeptide A: a conformational and comparative study. J Biomol Struct Dyn 1992 0.78
65 Construct validity of the abbreviated mental test in older medical inpatients. Dement Geriatr Cogn Disord 2003 0.78
66 Ageing and COPD affect different domains of nutritional status: the ECCE study. Eur Respir J 2010 0.78
67 Beta-alanine containing peptides: a novel molecular tool for the design of gamma-turns. Biopolymers 1992 0.78
68 Structural versatility of peptides containing C alpha, alpha-dialkylated glycines: conformational energy computations, i.r. absorption and 1H n.m.r. analysis of 1-aminocyclopropane-1-carboxylic acid homopeptides. Int J Biol Macromol 1989 0.78
69 Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras. Amino Acids 2009 0.78
70 Positive patch tests to Euro coins in nickel-sensitized patients. Br J Dermatol 2004 0.77
71 Haptoglobin from psoriatic patients exhibits decreased activity in binding haemoglobin and inhibiting lecithin-cholesterol acyltransferase activity. J Eur Acad Dermatol Venereol 2008 0.77
72 Solid phase synthesis and RNA-binding studies of a serum-resistant nucleo-epsilon-peptide. J Pept Sci 2009 0.77
73 Synthesis, characterization and hybridization studies of new nucleo-gamma-peptides based on diaminobutyric acid. J Pept Sci 2006 0.77
74 Reasons prompting digitalis therapy in the acute care hospital. J Gerontol A Biol Sci Med Sci 2001 0.77
75 Critical main-chain length for conformational conversion from 3(10)-helix to alpha-helix in polypeptides. J Biomol Struct Dyn 1990 0.77
76 Defect peptide chemistry: perturbations in the structure of a homopentapeptide induced by a guest residue interrupting side-chain regularity. Biopolymers 1994 0.77
77 Conformation and structure of linear peptides with regularly alternating L- and D-residues: structure of the blocked hexapeptide tert-butyloxycarbonyl-(D-alloisoleucyl-L-isoleucyl)3 methyl ester monohydrate. Int J Pept Protein Res 1995 0.77
78 Antihypertensive drug therapy and hypoglycemia in elderly diabetic patients treated with insulin and/or sulfonylureas. Gruppo Italiano di Farmacovigilanza nell'Anziano (GIFA). Eur J Epidemiol 1999 0.77
79 Digitalis in the treatment of heart failure in the elderly. The GIFA study results. Arch Gerontol Geriatr 2004 0.77
80 Structure of cyclic peptides: the crystal and solution conformation of cyclo(Phe-Phe-Aib-Leu-Pro). J Pept Res 1998 0.77
81 Crystal and molecular structure of n,n'-diethyl-n,n'-diphenylurea. Proc Natl Acad Sci U S A 1970 0.77
82 Multiple binding mode of reversible synthetic thrombin inhibitors. A comparative structural analysis. Biol Chem 1998 0.77
83 Bent oligonucleotide duplexes as HMGB1 inhibitors: a comparative study. Nucleosides Nucleotides Nucleic Acids 2007 0.76
84 Structural consequences of metal complexation of cyclo[Pro-Phe-Phe-Ala-Xaa]2 decapeptides. Chemistry 2001 0.76
85 Synthesis, characterization and hybridization studies of an alternate nucleo-epsilon/gamma-peptide: complexes formation with natural nucleic acids. Amino Acids 2008 0.76
86 Beta-alanine containing cyclic peptides with turned structure: the "pseudo type II beta-turn." VI. Biopolymers 1994 0.76
87 The crystal structure of alpha-thrombin-hirunorm IV complex reveals a novel specificity site recognition mode. Protein Sci 1999 0.76
88 Older age and in-hospital development of hypokalemia from loop diuretics: results from a multicenter survey. GIFA Investigators. Multicenter Italian Pharmacoepidemiologic Study Group. J Gerontol A Biol Sci Med Sci 2000 0.75
89 Optimum dose of digoxin. Lancet 1997 0.75
90 Conformation for a beta-cyclodextrin monosubstituted with a cyclic dipeptide. Proc Natl Acad Sci U S A 1992 0.75
91 Trends in prescribing calcium-channel blockers. GIFA Investigators. Gruppo Italiano di Farmacovigilanza nell'Anziano. Lancet 1998 0.75
92 Constrictive pericarditis and tuberculosis. Lancet 1997 0.75
93 Carotid endarterectomy in elderly patients. Lancet 2001 0.75
94 Evidence based case reports. Evidence based medicine is not magic. BMJ 1998 0.75
95 Clinical and echocardiographic characteristics of elderly hospitalized patients with high levels of NT-proBNP without clinical diagnosis of heart failure. Aging Clin Exp Res 2014 0.75
96 Conformational rigidity versus flexibility in a novel peptidic neurokinin A receptor antagonist. J Pept Sci 1997 0.75
97 Bioorganic stereochemistry. A study of the peptide oxazolones from Z-(Aib)n-OH (n = 2-4) in the solid state. Int J Pept Protein Res 1983 0.75
98 Association of serum creatinine and age with headache caused by nitrates. Gruppo Italiano di Farmacovigilanza nell'Anziano. Clin Pharmacol Ther 1995 0.75
99 The polypeptide 3(10)-helix as a template for molecular recognition studies. Structural characterization of a side-chain functionalized octapeptide. Bioorg Med Chem 1995 0.75
100 Specific interaction between cyclophilin and cyclic peptides. Biopolymers 1995 0.75
101 Radiolabeling approaches for cholecystokinin B receptor imaging. Biopolymers 2002 0.75
102 Conformational characterization of peptides rich in the cycloaliphatic C alpha,alpha-disubstituted glycine 1-aminocyclononane-1-carboxylic acid. J Pept Sci 1998 0.75
103 Bicyclic peptides: solid state conformation of cyclo(Glu-Leu- Pro-Gly-Lys-Leu-Pro-Gly)cyclo(1gamma-5epsilon)Gly. Biopolymers 1990 0.75
104 Neuronorm is a potent and water soluble neurokinin A receptor antagonist. Bioorg Med Chem Lett 1998 0.75
105 Unusual conformational preferences of beta-alanine containing cyclic peptides. VII. Biopolymers 1996 0.75
106 Stereochemical behavior of acyclic peptide-cation complexes. Biopolymers 1990 0.75
107 A hairpin-shaped peptide conformation stabilized by multiple intramolecular H-bonds for a linear alternating D,L hexapeptide. Biochem Biophys Res Commun 1982 0.75
108 Design of metal ion binding peptides. Biopolymers 1995 0.75
109 Synthesis and structural characterization of 6I,6II-diamino-6I,6II-dideoxy-cyclomaltoheptaose, a difunctionalized beta-cyclodextrin. Carbohydr Res 1996 0.75
110 Ion binding of cyclolinopeptide A: an NMR and CD conformational study. Biopolymers 1991 0.75
111 Preferred conformation of the tert-butoxycarbonyl-amino group in peptides. Int J Pept Protein Res 1980 0.75
112 Conformation of linear homo-oligoprolines. VII. N-pivaloyl-L-prolyl-D-proline methyl ester in the solid state. Int J Pept Protein Res 1982 0.75
113 The oxygen therapy. Curr Med Chem 2013 0.75
114 A second polymorph of a helical decapeptide. Pept Res 1994 0.75
115 Conformational behaviour of a cyclolinopeptide A analogue: two-dimensional NMR study of cyclo(Pro1-Pro-Phe-Phe-Ac6c-Ile-ala-Val8). J Pept Sci 1997 0.75
116 Use of antihypertensive drugs in the Italian hospitals. GIFA group. Gruppo Italiano di Farmacoepidemiologia nell'Anziano. Pharmacol Res 2000 0.75
117 Structure of N-acetyl-D-alanyl-D-alanine hydrate. An analogue of the COOH-terminal segment of peptidoglycan of bacterial cell walls. J Biol Chem 1981 0.75
118 First observation of a beta-turn conformation fused with the oxy-analogue of an alpha-turn: the molecular structure of a model peptide of the C-terminal part of gramicidin A. Biochem Biophys Res Commun 1983 0.75
119 Protected 1-3 segment of the peptaibol antibiotics alamethicin and hypelcin. Solid-state and solution study of a stereochemically constrained linear peptide. Int J Pept Protein Res 1983 0.75
120 Serum magnesium levels and cognitive impairment in hospitalized hypertensive patients. Magnes Res 2001 0.75
121 Non coded C alpha, alpha-disubstituted amino acids. X-ray diffraction analysis of a dipeptide containing (S)-alpha-methylserine. Int J Pept Protein Res 1993 0.75
122 Bioactive peptides: solid state, solution and molecular dynamics studies of a cyclolinopeptide A-related cystinyl cyclopentapeptide. Biopolymers 1994 0.75
123 Bicyclic peptides as type I/type II beta-turn scaffolds. Biopolymers 1996 0.75
124 Characterization at atomic resolution of peptide helical structures. Biopolymers 1992 0.75
125 [Aib5,6-D-Ala8]-cyclolinopeptide A, grown from a benzene/acetonitrile mixture. Acta Crystallogr C 1995 0.75
126 A review of the design, synthesis and biological activity of the bicyclic hexapeptide tachykinin NK2 antagonist MEN 10627. Regul Pept 1996 0.75
127 Studies on gliadin related peptides. I. Synthesis, purification and 1H n.m.r. characterization of the pentapeptide H-Tyr-(Gln)3-Pro-OH. Int J Pept Protein Res 1983 0.75
128 Specific interaction between bovine cyclophilin A and synthetic analogues of cyclolinopeptide A. J Biochem 1998 0.75
129 Conformation of diastereomeric peptide sequences: structural analysis of Z-D-Val-Ac6c-Gly-L-Phe-OMe. Biopolymers 1992 0.75
130 Specific IgA to lactic acid bacteria in feces of children consuming milk fermented by yoghurt symbiosis and Lactobacillus casei (Danone strain DN 114 001). Adv Exp Med Biol 2001 0.75
131 Association of peripheral venous disease with arterial endothelial dysfunction: a proof-of-concept study. Phlebology 2013 0.75
132 beta-Alanyl-beta-alanine in cyclic beta-turned peptides. Biopolymers 1991 0.75
133 Conformational analysis by NMR and distance geometry techniques of a peptide mimetic of the third helix of the Antennapedia homeodomain. J Pept Res 2005 0.75
134 Solution and solid state structure of an aib-containing cyclodecapeptide inhibiting the cholate uptake in hepatocytes. Biopolymers 1996 0.75
135 Conformational analysis of N-(tert.-amyloxycarbony-L-proline in the solid state and in solution. Int J Pept Protein Res 1979 0.75
136 Bioactive peptides: conformational studies of [Tyr4] cyclolinopeptide A. Biopolymers 1995 0.75
137 Structure of N-tert-butyloxycarbonyl-D-leucyl-L-phenylalanylethanolamide. An N alpha-protected analogue of the COOH-terminal dipeptide of linear gramicidins. J Biol Chem 1983 0.75
138 Synthesis and neurokinin antagonist activity of 2-benzylidene- and 2-benzyl-3-benzylamino quinuclidines. Farmaco 1993 0.75
139 Regularly alternating L,D-peptides. I. The double-stranded left-handed antiparallel beta-helix in the structure of Boc-(L-Val-D-Val)4-OMe. Biopolymers 1989 0.75
140 Self-association regions in the CARD of Bcl-10. Adv Exp Med Biol 2009 0.75
141 Trends of the characteristics and appropriateness of admissions to acute geriatric and medical wards in Italy from 1988 through 1993. Gruppo Italiano di Farmacovigilanza nell'Anziano--GIFA. Eur J Epidemiol 1996 0.75
142 Ala analogues of the cyclolinopeptide A. Biopolymers 1989 0.75
143 Conformational study of cyclolinopeptide A. A distance geometry and molecular dynamics approach. Int J Pept Protein Res 1991 0.75
144 Peptide antagonists of the PED-hPLD1 binding. Adv Exp Med Biol 2009 0.75
145 Preferred conformation of the benzyloxycarbonyl-amino group in peptides. Int J Pept Protein Res 1983 0.75
146 beta-Alanine containing peptides: gamma-turns in cyclotetrapeptides. Biopolymers 1993 0.75
147 Bioactive peptides: conformational study of a cystinyl cycloheptapeptide in its free and calcium complexed forms. Biopolymers 1993 0.75
148 Preferred conformation of peptides rich in Ac8c, a medium-ring alicyclic C (alpha,alpha)-disubstituted glycine. J Pept Sci 1997 0.75
149 Fluorescence studies on the binding between 1-47 fragment of cholecystokinin receptor CCK(A)-R(1-47) and nonsulfated cholecystokinin octapeptide CCK8. Biopolymers 2001 0.75
150 Conformational behaviour of C(alpha,alpha)-diphenylglycine: folded vs. extended structures in DphiG-containing tripeptides. J Pept Sci 1998 0.75
151 Evidences of complex formation between DABA-based nucleo-gamma-peptides with alternate configuration backbone. J Pept Sci 2009 0.75
152 Comparison of the conformations of cyclolinopeptide A in the solid state and in solution. Biopolymers 1989 0.75
153 Conformational studies of heterochiral peptides with diastereoisomeric residues: crystal and molecular structures of linear dipeptides derived from leucine, isoleucine, and allo-isoleucine. Biopolymers 1995 0.75