Published in World J Gastroenterol on February 14, 2013
Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome. Gastroenterology (2002) 2.52
Review article: serotonin receptors and transporters -- roles in normal and abnormal gastrointestinal motility. Aliment Pharmacol Ther (2004) 2.48
The enteric nervous system and regulation of intestinal motility. Annu Rev Physiol (1999) 2.34
The release of 5-hydroxytryptamine in relation to pressure exerted on the intestinal mucosa. J Physiol (1959) 2.17
Loss of interstitial cells of Cajal and development of electrical dysfunction in murine small bowel obstruction. J Physiol (2001) 1.88
Physiological and pharmacological investigations of small intestinal peristalsis. Translation of the article "Physiologische und pharmakologische Versuche über die Dünndarmperistaltik", Arch. Exp. Pathol. Pharmakol. 81, 55-129, 1917. Naunyn Schmiedebergs Arch Pharmacol (2006) 1.47
Participation of 5-HT3, 5-HT4, and nicotinic receptors in the peristaltic reflex of guinea pig distal colon. Am J Physiol (1996) 1.29
Hypertrophy of visceral smooth muscle. Anat Embryol (Berl) (1990) 1.22
Enteric neuronal plasticity and a reduced number of interstitial cells of Cajal in hypertrophic rat ileum. Gut (1998) 1.11
Hypertrophy of intestinal smooth muscle. Cell Tissue Res (1975) 1.08
Modulation of peristalsis in the guinea-pig isolated small intestine by exogenous and endogenous opioids. Br J Pharmacol (1992) 1.07
ATP and 5-HT are the principal neurotransmitters in the descending excitatory reflex pathway of the guinea-pig ileum. Neurogastroenterol Motil (2002) 1.06
5-HT4 receptor mediated facilitation of the emptying phase of the peristaltic reflex in the guinea-pig isolated ileum. Br J Pharmacol (1993) 1.03
Ligand-induced 5-HT3 receptor internalization in enteric neurons in rat ileum. Gastroenterology (2006) 1.00
Motor responses of rat hypertrophic intestine following chronic obstruction. Neurogastroenterol Motil (2004) 0.92
Biomechanical remodeling of the chronically obstructed Guinea pig small intestine. Dig Dis Sci (2007) 0.91
Hypertrophy of mucosa and serosa in the obstructed intestine of rats. J Anat (2001) 0.88
Spontaneous and bolus-induced motility in the chronically obstructed guinea-pig small intestine in vitro. Dig Dis Sci (2007) 0.88
The intestine as a model for neuronal plasticity. Arch Histol Cytol (1989) 0.87
5-HT receptor types in the rat ileum longitudinal muscle: focus on 5-HT2 receptors mediating contraction. Neurogastroenterol Motil (1997) 0.87
Gastrointestinal motility following small bowel obstruction in the opossum. J Surg Res (1986) 0.87
Preservation of peristaltic reflex in hypertrophied ileum of guinea pig. Am J Physiol (1995) 0.85
Intestinal chronic obstruction affects motor responsiveness of rat hypertrophic longitudinal and circular muscles. Neurogastroenterol Motil (2008) 0.84
Autoimmunity in membranous nephropathy targets aldose reductase and SOD2. J Am Soc Nephrol (2010) 2.22
Direct characterization of target podocyte antigens and auto-antibodies in human membranous glomerulonephritis: Alfa-enolase and borderline antigens. J Proteomics (2011) 1.28
Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity. FASEB J (2008) 1.17
Rational design of dualsteric GPCR ligands: quests and promise. Br J Pharmacol (2010) 1.07
Gefitinib inhibits invasive phenotype and epithelial-mesenchymal transition in drug-resistant NSCLC cells with MET amplification. PLoS One (2013) 1.05
Chemical basis of nitrogen recovery through the ureide pathway: formation and hydrolysis of S-ureidoglycine in plants and bacteria. ACS Chem Biol (2010) 1.02
Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation. PLoS One (2011) 1.00
Synergistic activity of letrozole and sorafenib on breast cancer cells. Breast Cancer Res Treat (2010) 1.00
Conserved alternative splicing of Arabidopsis transthyretin-like determines protein localization and S-allantoin synthesis in peroxisomes. Plant Cell (2010) 0.98
Calcein-AM is a detector of intracellular oxidative activity. Histochem Cell Biol (2004) 0.98
Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis. Pharmacol Res (2007) 0.97
Combinatorial co-expression of pheromone receptors, V2Rs. J Neurochem (2007) 0.97
Effect of the purinergic inhibitor oxidized ATP in a model of islet allograft rejection. Diabetes (2013) 0.97
Protective effect of proteinase-activated receptor 2 activation on motility impairment and tissue damage induced by intestinal ischemia/reperfusion in rodents. Am J Pathol (2006) 0.97
1,5-benzodiazepines. Part XIII. Substituted 4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepin-5-amines and 4H-imidazo[1,2-a][1,5]benzodiazepin-5-amines as analgesic, anti-inflammatory and/or antipyretic agents with low acute toxicity. Eur J Med Chem (2002) 0.97
Alterations of intestinal motor responsiveness in a model of mild mesenteric ischemia/reperfusion in rats. Life Sci (2002) 0.93
Inhibition of glutamine synthetase triggers apoptosis in asparaginase-resistant cells. Cell Physiol Biochem (2005) 0.91
Dose-dependent effects of platelet gel releasate on activities of human osteoblasts. J Periodontol (2007) 0.91
Combined use of anti-ErbB monoclonal antibodies and erlotinib enhances antibody-dependent cellular cytotoxicity of wild-type erlotinib-sensitive NSCLC cell lines. Mol Cancer (2012) 0.89
Newly identified antiatherosclerotic activity of methotrexate and adalimumab: complementary effects on lipoprotein function and macrophage cholesterol metabolism. Arthritis Rheumatol (2015) 0.89
Growth-related oncogene alpha induction of apoptosis in osteoarthritis chondrocytes. Arthritis Rheum (2002) 0.88
Molecular mechanisms underlying the antitumor activity of 3-aminopropanamide irreversible inhibitors of the epidermal growth factor receptor in non-small cell lung cancer. Neoplasia (2013) 0.87
Synthesis and pharmacological evaluation of 5H-[1]benzopyrano[4,3-d]pyrimidines effective as antiplatelet/analgesic agents. Bioorg Med Chem (2004) 0.87
Polyphenon E(R), a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis and tumorigenic PC3 by necroptosis. Carcinogenesis (2013) 0.87
Nuclear localization of NORs and centromeres in mouse oocytes during folliculogenesis. Mol Reprod Dev (2003) 0.86
A recent class of chemosensory neurons developed in mouse and rat. PLoS One (2011) 0.86
Structure-activity relationships and mechanism of action of Eph-ephrin antagonists: interaction of cholanic acid with the EphA2 receptor. ChemMedChem (2012) 0.86
The selective inhibition of inducible nitric oxide synthase prevents intestinal ischemia-reperfusion injury in mice. Nitric Oxide (2006) 0.85
Design, synthesis, and action of oxotremorine-related hybrid-type allosteric modulators of muscarinic acetylcholine receptors. J Med Chem (2006) 0.85
Protective role of μ opioid receptor activation in intestinal inflammation induced by mesenteric ischemia/reperfusion in mice. J Neurosci Res (2012) 0.85
Histamine in the control of gastric acid secretion: a topic review. Pharmacol Res (2003) 0.85
Synthesis, biological activity, QSAR and QSPR study of 2-aminobenzimidazole derivatives as potent H3-antagonists. Bioorg Med Chem (2004) 0.85
Serum thyroid-stimulating hormone as a predictor of cognitive impairment in an elderly cohort. Gerontology (2011) 0.85
Serine protease inhibition reduces post-ischemic granulocyte recruitment in mouse intestine. Am J Pathol (2011) 0.84
Antibody constant region peptides can display immunomodulatory activity through activation of the Dectin-1 signalling pathway. PLoS One (2012) 0.84
Polydeoxyribonucleotide promotes cyclobutane pyrimidine dimer repair in UVB-exposed dermal fibroblasts. Photodermatol Photoimmunol Photomed (2007) 0.84
Perturbation of the EphA2-EphrinA1 system in human prostate cancer cells by colonic (poly)phenol catabolites. J Agric Food Chem (2012) 0.83
Polyphenol rich botanicals used as food supplements interfere with EphA2-ephrinA1 system. Pharmacol Res (2011) 0.83
Differential infectious entry of human influenza A/NWS/33 virus (H1N1) in mammalian kidney cells. Virus Res (2010) 0.83
Trastuzumab emtansine is active on HER-2 overexpressing NSCLC cell lines and overcomes gefitinib resistance. Mol Cancer (2014) 0.83
PKC-dependent stimulation of EAAT3 glutamate transporter does not require the integrity of actin cytoskeleton. Neurochem Int (2006) 0.82
Intrapleural polymeric films containing cisplatin for malignant pleural mesothelioma in a rat tumour model: a preliminary study. Eur J Cardiothorac Surg (2009) 0.82
Time course assessment of methylmercury effects on C6 glioma cells: submicromolar concentrations induce oxidative DNA damage and apoptosis. J Neurosci Res (2002) 0.82
1,4-dioxane, a suitable scaffold for the development of novel M₃ muscarinic receptor antagonists. J Med Chem (2012) 0.81
Synthesis and biological evaluation of new non-imidazole H3-receptor antagonists of the 2-aminobenzimidazole series. Bioorg Med Chem (2005) 0.81
Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor. J Med Chem (2013) 0.80
Synthesis and biological evaluation of N-pyrazolyl-N'-alkyl/benzyl/phenylureas: a new class of potent inhibitors of interleukin 8-induced neutrophil chemotaxis. J Med Chem (2007) 0.80
Validation of a histamine H3 receptor model through structure-activity relationships for classical H3 antagonists. Bioorg Med Chem (2005) 0.80
1,8-Naphthyridines VII. New substituted 5-amino[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides and their isosteric analogues, exhibiting notable anti-inflammatory and/or analgesic activities, but no acute gastrolesivity. Eur J Med Chem (2007) 0.80
Antiplatelet and antithrombotic activities of essential oil from wild Ocotea quixos (Lam.) Kosterm. (Lauraceae) calices from Amazonian Ecuador. Pharmacol Res (2006) 0.80
Polyunsaturated fatty acid metabolism signature in ischemia differs from reperfusion in mouse intestine. PLoS One (2013) 0.80
Ocotea quixos Lam. essential oil: in vitro and in vivo investigation on its anti-inflammatory properties. Fitoterapia (2009) 0.79
Evidence for the involvement of 5-HT2A receptors in mild mesenteric ischemia/reperfusion dysfunctions in mice. Pharmacol Res (2007) 0.79
Modulatory effect of rRNA synthesis and ppUL83 nucleolar compartmentalization on human cytomegalovirus gene expression in vitro. J Cell Biochem (2009) 0.79
Antifibroblast antibodies from systemic sclerosis patients are internalized by fibroblasts via a caveolin-linked pathway. Arthritis Rheum (2002) 0.79
Three-dimensional localization and dynamics of centromeres in mouse oocytes during folliculogenesis. J Mol Histol (2004) 0.78
Dibasic non-imidazole histamine H3 receptor antagonists with a rigid biphenyl scaffold. Bioorg Med Chem Lett (2006) 0.78
Synthesis and stability in biological media of 1H-imidazole-1-carboxylates of ROS203, an antagonist of the histamine H3 receptor. Chem Biodivers (2008) 0.78
6-amino-4-oxo-1,3-diphenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carbonyl derivatives as a new class of potent inhibitors of Interleukin-8-induced neutrophil chemotaxis. Bioorg Med Chem (2009) 0.78
Sodium channel blockers: a patent review (2010 - 2014). Expert Opin Ther Pat (2014) 0.77
Identifying contact-mediated, localized toxic effects of MWCNT aggregates on epithelial monolayers: a single-cell monitoring toxicity assay. Nanotoxicology (2014) 0.77
Effects of subacute treatment with benzopyranopyrimidines in hemostasis and experimental thrombosis in mice. Life Sci (2004) 0.77
Synthesis and structure-activity relationships for biphenyl H3 receptor antagonists with moderate anti-cholinesterase activity. Bioorg Med Chem (2008) 0.77
Adhesion of human osteoblasts to titanium: A morpho-functional analysis with confocal microscopy. Micron (2009) 0.77
1,8-Naphthyridines v. novel N-substituted 5-amino-N,N-diethyl-9-isopropyl [1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6-carboxamides, as potent anti-inflammatory and/or analgesic agents completely devoid of acute gastrolesivity. Eur J Med Chem (2005) 0.77
Impaired phagocytosis in macrophages from patients affected by lysinuric protein intolerance. Mol Genet Metab (2012) 0.77
Imidazole H3-antagonists: relationship between structure and ex vivo binding to rat brain H3-receptors. Eur J Pharm Sci (2004) 0.76
Anti-fibroblast antibodies in systemic sclerosis. Isr Med Assoc J (2002) 0.76
1-Methyl and 1-(2-hydroxyalkyl)-5-(3-alkyl/cycloalkyl/phenyl/naphthylureido)-1H-pyrazole-4-carboxylic acid ethyl esters as potent human neutrophil chemotaxis inhibitors. Bioorg Med Chem (2009) 0.76
Free cholesterol alters macrophage morphology and mobility by an ABCA1 dependent mechanism. Atherosclerosis (2010) 0.76
In vitro and in vivo pharmacological analysis of imidazole-free histamine H3 receptor antagonists: promising results for a brain-penetrating H3 blocker with weak anticholinesterase activity. Naunyn Schmiedebergs Arch Pharmacol (2008) 0.76
Dibasic biphenyl H3 receptor antagonists: Steric tolerance for a lipophilic side chain. Eur J Med Chem (2011) 0.76
4-Aminopyridine derivatives with anticholinesterase and antiamnesic activity. Bioorg Med Chem Lett (2007) 0.76
The role of HB-donor groups in the heterocyclic polar fragment of H3-antagonists. I. Synthesis and biological assays. Farmaco (2003) 0.76