Published in J Orthop Res on February 25, 2013
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High fluoride and low calcium levels in drinking water is associated with low bone mass, reduced bone quality and fragility fractures in sheep. Osteoporos Int (2014) 0.79
Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B. Endocrinology (2007) 2.57
Utility of 3D multimodality imaging in the implantation of intracranial electrodes in epilepsy. Epilepsia (2015) 2.43
Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation. J Neurosci (2009) 2.07
Fracture healing under healthy and inflammatory conditions. Nat Rev Rheumatol (2012) 2.00
Bone mineralization defects and vitamin D deficiency: histomorphometric analysis of iliac crest bone biopsies and circulating 25-hydroxyvitamin D in 675 patients. J Bone Miner Res (2010) 1.88
Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor. Cell Metab (2010) 1.79
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Control of bone formation by the serpentine receptor Frizzled-9. J Cell Biol (2011) 1.77
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KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season. Endocrinology (2006) 1.66
Vitamin D deficiency induces early signs of aging in human bone, increasing the risk of fracture. Sci Transl Med (2013) 1.65
Variation in kisspeptin and RFamide-related peptide (RFRP) expression and terminal connections to gonadotropin-releasing hormone neurons in the brain: a novel medium for seasonal breeding in the sheep. Endocrinology (2008) 1.63
Bone morphogenetic protein type IA receptor signaling regulates postnatal osteoblast function and bone remodeling. J Biol Chem (2004) 1.62
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Impaired gastric acidification negatively affects calcium homeostasis and bone mass. Nat Med (2009) 1.52
Human apolipoprotein E isoforms differentially affect bone mass and turnover in vivo. J Bone Miner Res (2013) 1.47
The Fos-related antigen Fra-1 is an activator of bone matrix formation. EMBO J (2004) 1.46
Characterizing a mammalian circannual pacemaker. Science (2006) 1.45
The action of leptin on appetite-regulating cells in the ovine hypothalamus: demonstration of direct action in the absence of the arcuate nucleus. Endocrinology (2010) 1.45
Metaphyseal fracture healing in a sheep model of low turnover osteoporosis induced by hypothalamic-pituitary disconnection (HPD). J Orthop Res (2013) 1.42
Signal transduction pathways involved in mechanotransduction in bone cells. Biochem Biophys Res Commun (2006) 1.40
Mutations in WNT1 cause different forms of bone fragility. Am J Hum Genet (2013) 1.39
Infrared analysis of the mineral and matrix in bones of osteonectin-null mice and their wildtype controls. J Bone Miner Res (2003) 1.39
New insights of an old defense system: structure, function, and clinical relevance of the complement system. Mol Med (2010) 1.37
Micro-structural basis for particular vulnerability of the superolateral neck trabecular bone in the postmenopausal women with hip fractures. Bone (2011) 1.37
GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC. PLoS One (2012) 1.33
Kisspeptin is essential for the full preovulatory LH surge and stimulates GnRH release from the isolated ovine median eminence. Endocrinology (2011) 1.27
Canonical Wnt signaling inhibits osteoclastogenesis independent of osteoprotegerin. J Cell Biol (2013) 1.24
Increased bone mass is an unexpected phenotype associated with deletion of the calcitonin gene. J Clin Invest (2002) 1.24
Decrease in the osteocyte lacunar density accompanied by hypermineralized lacunar occlusion reveals failure and delay of remodeling in aged human bone. Aging Cell (2010) 1.24
The clock genes Period 2 and Cryptochrome 2 differentially balance bone formation. PLoS One (2010) 1.22
Feasibility of multimodal 3D neuroimaging to guide implantation of intracranial EEG electrodes. Epilepsy Res (2013) 1.20
The high mobility group transcription factor Sox8 is a negative regulator of osteoblast differentiation. J Cell Biol (2005) 1.19
Enhanced trabecular micro-architecture of the femoral neck in hip osteoarthritis vs. healthy controls: a micro-computer tomography study in postmenopausal women. Int Orthop (2012) 1.18
Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production. J Cell Biol (2010) 1.16
Proliferation of human-derived osteoblast-like cells depends on the cycle number and frequency of uniaxial strain. J Biomech (2002) 1.15
Early dynamization by reduced fixation stiffness does not improve fracture healing in a rat femoral osteotomy model. J Orthop Res (2009) 1.15
Kisspeptin cells in the ewe brain respond to leptin and communicate with neuropeptide Y and proopiomelanocortin cells. Endocrinology (2010) 1.15
Gelastic seizures: incidence, clinical and EEG features in adult patients undergoing video-EEG telemetry. Epilepsia (2014) 1.12
Fracture healing in mice under controlled rigid and flexible conditions using an adjustable external fixator. J Orthop Res (2010) 1.12
Resorbability of bone substitute biomaterials by human osteoclasts. Biomaterials (2004) 1.11
Bone formation in a long bone defect model using a platelet-rich plasma-loaded collagen scaffold. Biomaterials (2005) 1.11
Fhl2 deficiency results in osteopenia due to decreased activity of osteoblasts. EMBO J (2005) 1.11
CD44 is a determinant of inflammatory bone loss. J Exp Med (2005) 1.10
Pain regulation and health-related quality of life after thoracolumbar fractures of the spine. Eur Spine J (2007) 1.10
Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue. Aging Cell (2010) 1.09
Decellularized cartilage matrix as a novel biomatrix for cartilage tissue-engineering applications. Tissue Eng Part A (2012) 1.08
Age-dependent three-dimensional microcomputed tomography analysis of the human midpalatal suture. J Orofac Orthop (2007) 1.07
Effect of RF-amide-related peptide-3 on luteinizing hormone and follicle-stimulating hormone synthesis and secretion in ovine pituitary gonadotropes. Endocrinology (2009) 1.06
Experimental blunt chest trauma impairs fracture healing in rats. J Orthop Res (2010) 1.05
Evaluation of anatomic landmarks and safe zones for screw placement in the atlas via the posterior arch. Eur Spine J (2009) 1.05
Estradiol increases hematopoietic stem and progenitor cells independent of its actions on bone. Haematologica (2012) 1.05
Decreased bone formation and osteopenia in mice lacking alpha-calcitonin gene-related peptide. J Bone Miner Res (2004) 1.05
Effect of subchondral drilling on the microarchitecture of subchondral bone: analysis in a large animal model at 6 months. Am J Sports Med (2012) 1.05
Essential role of RSK2 in c-Fos-dependent osteosarcoma development. J Clin Invest (2005) 1.05
Paget's disease of bone: histologic analysis of 754 patients. J Bone Miner Res (2009) 1.05
Association of osteonecrosis and failure of hip resurfacing arthroplasty. Clin Orthop Relat Res (2009) 1.05
Telomerase-deficient mice exhibit bone loss owing to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment. J Bone Miner Res (2011) 1.04
Biomechanical evaluation for mechanisms of periprosthetic femoral fractures. J Trauma (2011) 1.04
Primary stability and strain distribution of cementless hip stems as a function of implant design. Clin Biomech (Bristol, Avon) (2011) 1.04
Hypothalamic expression of KISS1 and gonadotropin inhibitory hormone genes during the menstrual cycle of a non-human primate. Biol Reprod (2010) 1.03
Preliminary investigations on intradiscal pressures during daily activities: an in vivo study using the merino sheep. PLoS One (2013) 1.02
Temporary distraction and compression of a diaphyseal osteotomy accelerates bone healing. J Orthop Res (2008) 1.02
Leptin inhibits bone formation not only in rodents, but also in sheep. J Bone Miner Res (2006) 1.02
Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells. J Bone Miner Res (2011) 1.02
Increased bone formation in mice lacking apolipoprotein E. J Bone Miner Res (2004) 1.02
Estrogen receptor and Wnt signaling interact to regulate early gene expression in response to mechanical strain in osteoblastic cells. Biochem Biophys Res Commun (2010) 1.01
A three-dimensional collagen matrix as a suitable culture system for the comparison of cyclic strain and hydrostatic pressure effects on intervertebral disc cells. J Neurosurg Spine (2005) 1.01
Regulation of gene expression in intervertebral disc cells by low and high hydrostatic pressure. Eur Spine J (2006) 1.01
Bone microarchitecture of the calcaneus and its changes in aging: a histomorphometric analysis of 60 human specimens. J Orthop Res (2006) 1.00
Precision and accuracy of peripheral quantitative computed tomography (pQCT) in the mouse skeleton compared with histology and microcomputed tomography (microCT). J Bone Miner Res (2003) 1.00
Negative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2. PLoS One (2010) 1.00
In vivo degradation of low temperature calcium and magnesium phosphate ceramics in a heterotopic model. Acta Biomater (2011) 0.99
Calcitonin deficiency in mice progressively results in high bone turnover. J Bone Miner Res (2006) 0.99
Age- and sex-related changes of humeral head microarchitecture: histomorphometric analysis of 60 human specimens. J Orthop Res (2010) 0.98
Mechanical evaluation of different techniques for Achilles tendon repair. Arch Orthop Trauma Surg (2007) 0.96
Femoral component loosening after hip resurfacing arthroplasty. Skeletal Radiol (2010) 0.96
Fabrication, mechanical and in vivo performance of polycaprolactone/tricalcium phosphate composite scaffolds. Acta Biomater (2012) 0.96
Decreased bone formation and increased osteoclastogenesis cause bone loss in mucolipidosis II. EMBO Mol Med (2013) 0.96
Redefining the limits of day length responsiveness in a seasonal mammal. Endocrinology (2007) 0.95
The role of calcitonin and alpha-calcitonin gene-related peptide in bone formation. Arch Biochem Biophys (2008) 0.95
Effect of partial meniscectomy at the medial posterior horn on tibiofemoral contact mechanics and meniscal hoop strains in human knees. J Orthop Res (2011) 0.95