Published in Angew Chem Int Ed Engl on March 06, 2013
trans-Cyclooctene--a stable, voracious dienophile for bioorthogonal labeling. Curr Opin Chem Biol (2013) 1.25
Bioorthogonal chemistry: strategies and recent developments. Chem Commun (Camb) (2013) 1.19
Expanding room for tetrazine ligations in the in vivo chemistry toolbox. Curr Opin Chem Biol (2013) 1.01
Conformationally Strained trans-Cyclooctene with Improved Stability and Excellent Reactivity in Tetrazine Ligation. Chem Sci (2014) 0.99
Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification. J Am Chem Soc (2014) 0.90
Genetically encoded unstrained olefins for live cell labeling with tetrazine dyes. Chem Commun (Camb) (2014) 0.88
Bioorthogonal chemistry: implications for pretargeted nuclear (PET/SPECT) imaging and therapy. Am J Nucl Med Mol Imaging (2014) 0.88
Improved metabolic stability for 18F PET probes rapidly constructed via tetrazine trans-cyclooctene ligation. Bioconjug Chem (2015) 0.84
Metabolic glycan imaging by isonitrile-tetrazine click chemistry. Chembiochem (2013) 0.84
Fluorogenic protein labeling using a genetically encoded unstrained alkene. Chem Sci (2016) 0.82
N-terminal modification of proteins with o-aminophenols. J Am Chem Soc (2014) 0.82
Are glycan biosensors an alternative to glycan microarrays? Anal Methods (2014) 0.82
Glycans in pathogenic bacteria--potential for targeted covalent therapeutics and imaging agents. Chem Commun (Camb) (2014) 0.81
Dual-sugar imaging using isonitrile and azido-based click chemistries. Org Biomol Chem (2013) 0.78
Fluorogenic Strain-Promoted Alkyne-Diazo Cycloadditions. Chemistry (2015) 0.78
A novel approach to decrease sialic acid expression in cells by a C-3-modified N-acetylmannosamine. J Biol Chem (2014) 0.78
Modular and orthogonal synthesis of hybrid polymers and networks. Chem Commun (Camb) (2015) 0.77
Expanding the scope of cyclopropene reporters for the detection of metabolically engineered glycoproteins by Diels-Alder reactions. Beilstein J Org Chem (2014) 0.77
Vinylboronic Acids as Fast Reacting, Synthetically Accessible, and Stable Bioorthogonal Reactants in the Carboni-Lindsey Reaction. Angew Chem Int Ed Engl (2016) 0.76
Chemistry-enabled methods for the visualization of cell-surface glycoproteins in Metazoans. Glycoconj J (2015) 0.76
Spatiotemporal control of cell-cell reversible interactions using molecular engineering. Nat Commun (2016) 0.75
Quantum Chemical Calculations and Experimental Validation of the Photoclick Reaction for Fluorescent Labeling of the 5' cap of Eukaryotic mRNAs. ChemistryOpen (2015) 0.75
Simultaneous Site-Specific Dual Protein Labeling Using Protein Prenyltransferases. Bioconjug Chem (2015) 0.75
Thermally Induced Silane Dehydrocoupling on Silicon Nanostructures. Angew Chem Int Ed Engl (2016) 0.75
Advances in cell surface glycoengineering reveal biological function. Glycobiology (2016) 0.75
Chemical Methods for Encoding and Decoding of Posttranslational Modifications. Cell Chem Biol (2016) 0.75
Physiological Effects of Ac4ManNAz and Optimization of Metabolic Labeling for Cell Tracking. Theranostics (2017) 0.75
Tetrazine-Containing Amino Acid for Peptide Modification and Live Cell Labeling. PLoS One (2015) 0.75
Bioorthogonal Fluorescent Labelling of Biopolymers via Inverse Electron Demand Diels-Alder Reactions. Chembiochem (2017) 0.75
Sialylation is essential for early development in mice. Proc Natl Acad Sci U S A (2002) 2.15
Remodeling of lipid droplets during lipolysis and growth in adipocytes. J Biol Chem (2012) 1.29
Versatile biosynthetic engineering of sialic acid in living cells using synthetic sialic acid analogues. J Biol Chem (2001) 1.22
No overall hyposialylation in hereditary inclusion body myopathy myoblasts carrying the homozygous M712T GNE mutation. Biochem Biophys Res Commun (2005) 1.16
CEACAM1 (CD66a) mediates delay of spontaneous and Fas ligand-induced apoptosis in granulocytes. Eur J Immunol (2005) 1.13
Structural basis of multivalent binding to wheat germ agglutinin. J Am Chem Soc (2010) 1.11
Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface. J Biol Chem (2004) 1.11
Muropeptide rescue in Bacillus subtilis involves sequential hydrolysis by beta-N-acetylglucosaminidase and N-acetylmuramyl-L-alanine amidase. J Bacteriol (2010) 1.04
Enhanced sialylation of EPO by overexpression of UDP-GlcNAc 2-epimerase/ManAc kinase containing a sialuria mutation in CHO cells. FEBS Lett (2007) 1.03
Engineering the sialic acid in organs of mice using N-propanoylmannosamine. Biochim Biophys Acta (2006) 1.02
Deficiency of CD26 results in a change of cytokine and immunoglobulin secretion after stimulation by pokeweed mitogen. Eur J Immunol (2003) 0.99
Sialic acid metabolism is involved in the regulation of gene expression during neuronal differentiation of PC12 cells. Glycoconj J (2008) 0.98
The cell adhesion receptor carcinoembryonic antigen-related cell adhesion molecule 1 regulates nucleocytoplasmic trafficking of DNA polymerase delta-interacting protein 38. J Biol Chem (2007) 0.96
Biochemical engineering of cell surface sialic acids stimulates axonal growth. J Neurosci (2002) 0.96
Structure and function of N-acetylglucosamine kinase. Identification of two active site cysteines. Eur J Biochem (2002) 0.93
Evidence for dynamic interplay of different oligomeric states of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase by biophysical methods. J Mol Biol (2007) 0.93
Regulation and pathophysiological implications of UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) as the key enzyme of sialic acid biosynthesis. Biol Chem (2009) 0.91
One-pot procedure for diazo transfer and azide-alkyne cycloaddition: triazole linkages from amines. Org Lett (2007) 0.91
Comparative proteomics of rat liver and Morris hepatoma 7777 plasma membranes. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 0.90
N-Propionylmannosamine-induced over-expression and secretion of thioredoxin leads to neurite outgrowth of PC12 cells. Biochem Biophys Res Commun (2010) 0.90
Carba-sugars activate the glmS-riboswitch of Staphylococcus aureus. ACS Chem Biol (2011) 0.90
Quantification of nucleotide-activated sialic acids by a combination of reduction and fluorescent labeling. Anal Chem (2010) 0.90
The neural cell adhesion molecule is associated with major components of the cytoskeleton. Biochem Biophys Res Commun (2003) 0.90
Cytoplasmic domain of NCAM 180 reduces NCAM-mediated neurite outgrowth. J Neurosci Res (2004) 0.89
Selective inhibition of polysialyltransferase ST8SiaII by unnatural sialic acids. Exp Cell Res (2004) 0.89
2',3'-Dialdehydo-UDP-N-acetylglucosamine inhibits UDP-N-acetylglucosamine 2-epimerase, the key enzyme of sialic acid biosynthesis. FEBS Lett (2002) 0.87
Epigenetically mediated loss of UDP-GlcNAc 2-epimerase/ManNAc kinase expression in hyposialylated cell lines. Biochem Biophys Res Commun (2003) 0.86
Rapid labeling of metabolically engineered cell-surface glycoconjugates with a carbamate-linked cyclopropene reporter. Bioconjug Chem (2013) 0.86
The intracellular concentration of sialic acid regulates the polysialylation of the neural cell adhesion molecule. FEBS Lett (2005) 0.86
Biochemical engineering of the acyl side chain of sialic acids stimulates integrin-dependent adhesion of HL60 cells to fibronectin. J Mol Med (Berl) (2002) 0.86
GLIS, a bioactive proteoglycan fraction from Ganoderma lucidum, displays anti-tumour activity by increasing both humoral and cellular immune response. Life Sci (2010) 0.85
Crystal structures of HIV-1 Tat-derived nonapeptides Tat-(1-9) and Trp2-Tat-(1-9) bound to the active site of dipeptidyl-peptidase IV (CD26). J Biol Chem (2005) 0.85
NMR spectroscopic determination of the solution structure of a branched nucleic acid from residual dipolar couplings by using isotopically labeled nucleotides. Angew Chem Int Ed Engl (2004) 0.85
Synthesis and biochemical properties of reversible inhibitors of UDP-N-acetylglucosamine 2-epimerase. Angew Chem Int Ed Engl (2004) 0.85
Increased expression of the selectin ligand sialyl-Lewis(x) by biochemical engineering of sialic acids. Exp Cell Res (2004) 0.85
Biochemical engineering of the N-acyl side chain of sialic acids alters the kinetics of a glycosylated potassium channel Kv3.1. FEBS Lett (2011) 0.85
In vivo stimulation of early peripheral axon regeneration by N-propionylmannosamine in the presence of polysialyltransferase ST8SIA2. J Neural Transm (Vienna) (2015) 0.84
Phospholipase Cgamma binds alpha1beta1 integrin and modulates alpha1beta1 integrin-specific adhesion. J Biol Chem (2001) 0.84
Activation of B lymphocytes by GLIS, a bioactive proteoglycan from Ganoderma lucidum. Life Sci (2002) 0.83
Sialic acid biosynthesis: stereochemistry and mechanism of the reaction catalyzed by the mammalian UDP-N-acetylglucosamine 2-epimerase. J Am Chem Soc (2003) 0.83
Crystal structures of N-acetylmannosamine kinase provide insights into enzyme activity and inhibition. J Biol Chem (2012) 0.83
Synthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the mitochondrial death pathway. Apoptosis (2011) 0.83
Rapid screening of lectins for multivalency effects with a glycodendrimer microarray. Chembiochem (2010) 0.83
PDGF-BB enhances alpha1beta1 integrin-mediated activation of the ERK/AP-1 pathway involved in collagen matrix remodeling by rat mesangial cells. J Cell Physiol (2004) 0.83
Novel UDP-glycal derivatives as transition state analogue inhibitors of UDP-GlcNAc 2-epimerase. J Org Chem (2004) 0.82
Homeostatic regulation of NCAM polysialylation is critical for correct synaptic targeting. Cell Mol Life Sci (2011) 0.82
The key enzyme of sialic acid biosynthesis (GNE) promotes neurite outgrowth of PC12 cells. Neuroreport (2008) 0.82
Glycosidated phospholipids: uncoupling of signalling pathways at the plasma membrane. Br J Pharmacol (2010) 0.81
Purification and characterization of N-acetylneuraminic acid-9-phosphate synthase from rat liver. Glycobiology (2002) 0.81
Experimental approaches to interfere with the polysialylation of the neural cell adhesion molecule in vitro and in vivo. J Neurochem (2007) 0.81
The 3D structure of rat DPPIV/CD26 as obtained by cryo-TEM and single particle analysis. Biochem Biophys Res Commun (2003) 0.81
Biochemical engineering of the N-acyl side chain of sialic acid leads to increased calcium influx from intracellular compartments and promotes differentiation of HL60 cells. FEBS Lett (2004) 0.81
Occurrence of the human tumor-specific antigen structure Galβ1-3GalNAcα- (Thomsen-Friedenreich) and related structures on gut bacteria: prevalence, immunochemical analysis and structural confirmation. Glycobiology (2011) 0.80
Domain-specific characteristics of the bifunctional key enzyme of sialic acid biosynthesis, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase. Biochem J (2004) 0.80
Asymmetric PPCys: strongly fluorescing NIR labels. Chem Commun (Camb) (2010) 0.80
3D structure of the CD26-ADA complex obtained by cryo-EM and single particle analysis. Biochem Biophys Res Commun (2004) 0.80
Efficient N-terminal glycoconjugation of proteins by the N-end rule. Chembiochem (2008) 0.80
Expression, purification, and characterization of human dipeptidyl peptidase IV/CD26 in Sf9 insect cells. Protein Expr Purif (2002) 0.80
The cytoplasmic tail of the alpha3 integrin subunit promotes neurite outgrowth in PC12 cells. J Neurosci Res (2005) 0.80
Clustering-induced signaling of CEACAM1 in PC12 cells. Biol Chem (2002) 0.80
Novel cytosolic binding partners of the neural cell adhesion molecule: mapping the binding domains of PLC gamma, LANP, TOAD-64, syndapin, PP1, and PP2A. Biochemistry (2005) 0.80
Mechanism of multivalent carbohydrate-protein interactions studied by EPR spectroscopy. Angew Chem Int Ed Engl (2011) 0.80
Probing multivalent carbohydrate-lectin interactions by an enzyme-linked lectin assay employing covalently immobilized carbohydrates. Bioorg Med Chem (2007) 0.80
Carbamate-linked lactose: design of clusters and evidence for selectivity to block binding of human lectins to (neo)glycoproteins with increasing degree of branching and to tumor cells. Bioconjug Chem (2009) 0.80
Characterization of ligand binding to the bifunctional key enzyme in the sialic acid biosynthesis by NMR: I. Investigation of the UDP-GlcNAc 2-epimerase functionality. J Biol Chem (2004) 0.79
Glucosamine-glycerophospholipids that activate cell-matrix adhesion and migration. J Med Chem (2005) 0.79
Fluorescent conjugated block copolymer nanoparticles by controlled mixing. Chem Commun (Camb) (2012) 0.79
Efficient labelling of enzymatically synthesized vinyl-modified DNA by an inverse-electron-demand Diels-Alder reaction. Chem Commun (Camb) (2014) 0.79
De novo sequencing of peptides on single resin beads by MALDI-FTICR tandem mass spectrometry. J Am Soc Mass Spectrom (2009) 0.79
Molecular mechanism and structural basis of interactions of dipeptidyl peptidase IV with adenosine deaminase and human immunodeficiency virus type-1 transcription transactivator. Eur J Cell Biol (2011) 0.79
Mass spectrometry-based analysis of rat liver and hepatocellular carcinoma Morris hepatoma 7777 plasma membrane proteome. Anal Chem (2013) 0.79
Effects of anti-alpha1 integrin subunit antibody on anti-Thy-1 glomerulonephritis. Lab Invest (2002) 0.78
Orthogonally protected sugar diamino acids as building blocks for linear and branched oligosaccharide mimetics. Angew Chem Int Ed Engl (2005) 0.78
Locally resolved membrane binding affinity of the N-terminus of α-synuclein. Biochemistry (2012) 0.78
Synthesis and X-ray structure analysis of a heptacoordinate titanium(IV)-bis-chelate with enhanced in vivo antitumor efficacy. Chem Commun (Camb) (2012) 0.78
Invasion of Trypanosoma cruzi into host cells is impaired by N-propionylmannosamine and other N-acylmannosamines. Glycoconj J (2011) 0.78
The ether lipid inositol-C2-PAF is a potent inhibitor of cell proliferation in HaCaT cells. Chembiochem (2006) 0.78
Preparation of carbohydrate arrays by using Diels-Alder reactions with inverse electron demand. Chemistry (2012) 0.78
Dipeptidyl peptidase IV/CD26 in T cell activation, cytokine secretion and immunoglobulin production. Adv Exp Med Biol (2003) 0.78
Terminal alkenes as versatile chemical reporter groups for metabolic oligosaccharide engineering. Chemistry (2014) 0.78
UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, functionally expressed in and purified from Escherichia coli, yeast, and insect cells. Protein Expr Purif (2004) 0.77
High-affinity multivalent wheat germ agglutinin ligands by one-pot click reaction. Beilstein J Org Chem (2012) 0.77
Synthetic polyglutamylation of dual-functional MTX ligands for enhanced combined cytotoxicity of poly(I:C) nanoplexes. Mol Pharm (2014) 0.77
Identification of members of the annexin family in the detergent-insoluble fraction of rat Morris hepatoma plasma membranes. J Chromatogr A (2006) 0.77
Involvement of sialic acid in the regulation of γ--aminobutyric acid uptake activity of γ-aminobutyric acid transporter 1. Glycobiology (2010) 0.77
[Human lectins and their correspondent glycans in cell biology and clinical medicine]. Med Klin (Munich) (2003) 0.76
Structural investigation of multivalent carbohydrate-protein interactions using synthetic biomolecules. Curr Opin Chem Biol (2013) 0.76
Metabolic glycoengineering of mesenchymal stromal cells with N-propanoylmannosamine. Glycobiology (2013) 0.76
Characterization of ligand binding to the bifunctional key enzyme in the sialic acid biosynthesis by NMR: II. Investigation of the ManNAc kinase functionality. J Biol Chem (2004) 0.76
Metabolism of galactose in the brain and liver of rats and its conversion into glutamate and other amino acids. J Neural Transm (Vienna) (2008) 0.76
Interaction of human dipeptidyl peptidase IV and human immunodeficiency virus type-1 transcription transactivator in Sf9 cells. Virol J (2010) 0.75
Liver-specific increase of UTP and UDP-sugar concentrations in rats induced by dietary vitamin B6-deficiency and its relation to complex N-glycan structures of liver membrane-proteins. Glycoconj J (2007) 0.75
Stereoselective synthesis of 1,1'-linked alpha-l-lyxopyranosyl beta-d-glucopyranoside, the proposed biosynthetic precursor of the FG ring system of avilamycins. Carbohydr Res (2008) 0.75
N-propanoylmannosamine interferes with O-GlcNAc modification of the tyrosine 3-monooxygenase and stimulates dopamine secretion. J Neurosci Res (2008) 0.75
Stimulation of human peripheral blood mononuclear cells by the sialic acid precursor N-propanoylmannosamine. Glycoconj J (2013) 0.75
Unexpected formation of complex bridged tetrazoles via intramolecular 1,3-dipolar cycloaddition of 1,2-O-cyanoalkylidene derivatives of 3-azido-3-deoxy-D-allose. Carbohydr Res (2007) 0.75