Ccr2-64i and Ccr5 Δ32 Polymorphisms in Patients with Late-Onset Alzheimer's disease; A Study from Iran (Ccr2-64i And Ccr5 Δ32 Polymorphisms in Alzheimer's disease).

PubWeight™: 0.87‹?›

🔗 View Article (PMC 3586912)

Published in Iran J Basic Med Sci on July 01, 2012

Authors

Hamid Reza Khorram Khorshid1, Mehdi Manoochehri, Leila Nasehi, Mina Ohadi, Mehdi Rahgozar, Koorosh Kamali

Author Affiliations

1: Genetics Research Centre, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.

Articles cited by this

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell (1996) 17.81

Chemokines: a new classification system and their role in immunity. Immunity (2000) 13.03

Inflammation and Alzheimer's disease. Neurobiol Aging (2000) 12.56

The biology of chemokines and their receptors. Annu Rev Immunol (2000) 9.81

Chemokines and leukocyte traffic. Nature (1998) 9.79

Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial. JAMA (2003) 6.34

Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study. Science (1997) 5.91

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease. Nat Med (2007) 5.87

Chemokine receptors: gateways to inflammation and infection. Nat Med (1996) 3.56

Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients. J Clin Invest (1999) 3.21

Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR. Neurosci Lett (1987) 3.13

Chemokines and their receptors: drug targets in immunity and inflammation. Annu Rev Pharmacol Toxicol (2008) 3.04

Inflammatory processes in Alzheimer's disease. J Neuroimmunol (2007) 2.91

Effect of non-steroidal anti-inflammatory drugs on risk of Alzheimer's disease: systematic review and meta-analysis of observational studies. BMJ (2003) 2.74

CD36 mediates the innate host response to beta-amyloid. J Exp Med (2003) 2.65

NSAIDs and Alzheimer disease: epidemiological, animal model and clinical studies. Neurobiol Aging (2006) 2.55

Properties of monocyte chemotactic and activating factor (MCAF) purified from a human fibrosarcoma cell line. J Exp Med (1990) 2.40

CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils. Am J Pathol (2002) 2.22

Defining molecular targets to prevent Alzheimer disease. Arch Neurol (2005) 2.02

Chemokine receptor homo- or heterodimerization activates distinct signaling pathways. EMBO J (2001) 1.94

Inflammation and Alzheimer's disease: possible role of periodontal diseases. Alzheimers Dement (2007) 1.82

Mechanisms of microglia accumulation in Alzheimer's disease: therapeutic implications. Trends Pharmacol Sci (2008) 1.71

Morphologic association between microglia and senile plaque amyloid in Alzheimer's disease. Neurosci Lett (1990) 1.51

Glial cells and inflammation in Parkinson's disease: a role in neurodegeneration? Ann Neurol (1998) 1.47

Immunohistochemical study of the beta-chemokine receptors CCR3 and CCR5 and their ligands in normal and Alzheimer's disease brains. Am J Pathol (1998) 1.29

Loss of CCR2 expression and functional response to monocyte chemotactic protein (MCP-1) during the differentiation of human monocytes: role of secreted MCP-1 in the regulation of the chemotactic response. Blood (1999) 1.24

Lymphocyte responses to chemokines. Int Rev Immunol (1998) 1.17

Peripheral T cells overexpress MIP-1alpha to enhance its transendothelial migration in Alzheimer's disease. Neurobiol Aging (2006) 1.13

Chemokines (RANTES and MCP-1) and chemokine-receptors (CCR2 and CCR5) gene polymorphisms in Alzheimer's and Parkinson's disease. Neurosci Lett (2004) 0.95

Synthetic Alzheimer amyloid beta/A4 peptides enhance production of complement C3 component by cultured microglial cells. Brain Res (1993) 0.95

The frequency of CCR5Delta32 and CCR2-64I in southern Iranian normal population. Immunol Lett (2005) 0.86

CCR2-64I polymorphism and CCR5Delta32 deletion in patients with Alzheimer's disease. J Neurol Sci (2004) 0.84

Association between the polymorphism of CCR5 and Alzheimer's disease: results of a study performed on male and female patients from Northern Italy. Ann N Y Acad Sci (2006) 0.83

The chemokine receptor CCR5-Delta32 gene mutation is not protective against Alzheimer's disease. Neurosci Lett (2004) 0.79

Articles by these authors

An epidemiological survey of psychiatric disorders in Iran. Clin Pract Epidemiol Ment Health (2005) 2.85

Ultrasonography of longus colli muscle: A reliability study on healthy subjects and patients with chronic neck pain. J Bodyw Mov Ther (2009) 1.16

Prevalence of obsessive-compulsive disorder in Iran. BMC Psychiatry (2004) 1.15

Association between the DRD2 A1 allele and opium addiction in the Iranian population. Am J Med Genet B Neuropsychiatr Genet (2005) 1.06

Stroke epidemiology and one-month fatality among an urban population in Iran. Int J Stroke (2011) 0.91

Association of the dopamine transporter gene (DAT1) core promoter polymorphism -67T variant with schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2004) 0.89

Positive effect of septimeb™ on mortality rate in severe sepsis: a novel non antibiotic strategy. Daru (2012) 0.89

Design and simulation of a new powered gait orthosis for paraplegic patients. Prosthet Orthot Int (2012) 0.88

A point mutation at the calreticulin gene core promoter conserved sequence in a case of schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2006) 0.88

The effect of Kangaroo Care on behavioral responses to pain of an intramuscular injection in neonates. J Spec Pediatr Nurs (2008) 0.86

Safety and efficacy of Setarud (IMOD TM ) among people living with HIV/AIDS: a review. Recent Pat Antiinfect Drug Discov (2012) 0.85

Comparison of modified Ashworth scale and Hoffmann reflex in study of spasticity. Acta Med Iran (2010) 0.84

Low back pain prevalence and associated factors in Iranian population: findings from the national health survey. Pain Res Treat (2012) 0.83

Discrepancy in the frequency of Y chromosome microdeletions among Iranian infertile men with azoospermia and severe oligozoospermia. Genet Test Mol Biomarkers (2012) 0.83

Echocardiography and management of sick neonates in the intensive care unit. Congenit Heart Dis (2008) 0.83

Association study of the TNF-α -1031T/C and VEGF +450G/C polymorphisms with susceptibility to endometriosis. Gynecol Endocrinol (2013) 0.81

The XmnI and BCL11A single nucleotide polymorphisms may help predict hydroxyurea response in Iranian β-thalassemia patients. Hemoglobin (2012) 0.81

Evaluation of a novel powered hip orthosis for walking by a spinal cord injury patient: a single case study. Prosthet Orthot Int (2012) 0.81

Evaluation of a novel powered gait orthosis for walking by a spinal cord injury patient. Prosthet Orthot Int (2012) 0.81

Effect of cannabinoid receptor activation on spreading depression. Iran J Basic Med Sci (2012) 0.80

Post marketing surveillance on safety and efficacy of IMOD in Iranian patients with HIV/AIDS. Infect Disord Drug Targets (2013) 0.80

Lack of Association between Tumor Necrosis Factor-alpha -308 G/A Polymorphism and Risk of Developing Late-Onset Alzheimer's Disease in an Iranian Population. Avicenna J Med Biotechnol (2009) 0.79

Functional Status Assessment of COPD Based on Ability to Perform Daily Living Activities: A Systematic Review of Paper and Pencil Instruments. Glob J Health Sci (2015) 0.79

Early fetal gender determination using real-time PCR analysis of cell-free fetal DNA during 6th-10th weeks of gestation. Acta Med Iran (2013) 0.79

Association of CALHM1 Gene Polymorphism with Late Onset Alzheimer's Disease in Iranian Population. Avicenna J Med Biotechnol (2010) 0.78

Iranian Oncologists' Attitude towards Fertility Preservation in a Sample Group. J Reprod Infertil (2011) 0.77

A mutation in the calreticulin gene promoter in a family case of schizoaffective disorder leads to its aberrant transcriptional activation. Brain Res (2008) 0.77

Molecular characterization of CTX-Mβ-lactamases among Klebsiella pneumoniae isolated from patients at Tehran hospitals. Indian J Med Microbiol (2011) 0.77

Exceptional expansion and conservation of a CT-repeat complex in the core promoter of PAXBP1 in primates. Am J Primatol (2014) 0.77

Biased homozygous haplotypes across the human caveolin 1 upstream purine complex in Parkinson's disease. J Mol Neurosci (2013) 0.76

Parental attitudes toward fertility preservation in boys with cancer: context of different risk levels of infertility and success rates of fertility restoration. Fertil Steril (2013) 0.76

Mutation Analysis of SLC20A2 and SPP2 as Candidate Genes for Familial Idiopathic Basal Ganglia Calcification. Avicenna J Med Biotechnol (2013) 0.76

Association Study of the TREM2 Gene and Identification of a Novel Variant in Exon 2 in Iranian Patients with Late-Onset Alzheimer's Disease. Med Princ Pract (2015) 0.75

New Variations in the Promoter Regions of Human DOCK4 and RAP1A Genes, and Coding Regions of RAP1A in Sporadic Breast Tumors. Avicenna J Med Biotechnol (2009) 0.75

The effects of nursing discharge plan (post-discharge education and follow-up) on self-care ability in patients with chronic schizophrenia hospitalized in Razi psychiatric Center. Iran J Nurs Midwifery Res (2011) 0.75

Comparing the effect of auditory-only and auditory-visual modes in two groups of Persian children using cochlear implants: a randomized clinical trial. Int J Pediatr Otorhinolaryngol (2013) 0.75

Characterization of immune responses induced by combined clade-A HIV-1 recombinant adenovectors in mice. Iran J Immunol (2010) 0.75

Validation and reliability test of Persian version of The Spirituality and Spiritual Care Rating Scale (SSCRS). J Clin Nurs (2010) 0.75

Aberrant expression of Activating Transcription Factor 6 (ATF6) in major psychiatric disorders. Psychiatry Res (2012) 0.75

DNA repair gene XRCC1 and XRCC4 variations and risk of endometriosis: an association study. Gynecol Obstet Invest (2015) 0.75

Association Study of IL-4 -590 C/T and DDX39B -22 G/C Polymorphisms with the Risk of Late-Onset Alzheimer's Disease in Iranian Population. Curr Aging Sci (2015) 0.75

The evaluation of modified foot orthosis on muscle activity and kinetic in a subject with flexible flat foot : single case study. Prosthet Orthot Int (2013) 0.75

Utility of the multivariate approach in predicting β-thalassemia intermedia or β-thalassemia major types In Iranian patients. Hemoglobin (2013) 0.75

Overexpression of the MUC1 Gene in Iranian Women with Breast Cancer Micrometastasis. Asian Pac J Cancer Prev (2016) 0.75

Narrative discourse impairments in Persian-speaking persons with traumatic brain injury: a pilot study. Folia Phoniatr Logop (2014) 0.75