Delivery of definable number of drug or growth factor loaded poly(DL-lactic acid-co-glycolic acid) microparticles within human embryonic stem cell derived aggregates.

PubWeight™: 1.45‹?› | Rank: Top 5%

🔗 View Article (PMID 23500059)

Published in J Control Release on March 14, 2013

Authors

Omar Qutachi1, Kevin M Shakesheff, Lee D K Buttery

Author Affiliations

1: Wolfson Centre for Stem Cells Tissue Engineering and Modelling, Centre of Biomolecular Sciences, School of Pharmacy, University of Nottingham, Nottingham, UK.

Articles by these authors

In vitro differentiation and in vivo mineralization of osteogenic cells derived from human embryonic stem cells. Tissue Eng (2004) 1.59

Leukocyte-inspired biodegradable particles that selectively and avidly adhere to inflamed endothelium in vitro and in vivo. Proc Natl Acad Sci U S A (2003) 1.48

The support of neural stem cells transplanted into stroke-induced brain cavities by PLGA particles. Biomaterials (2009) 1.36

A simple method for the simultaneous isolation of stellate cells and hepatocytes from rat liver tissue. Mol Cell Biochem (2003) 1.18

Induction of human osteoprogenitor chemotaxis, proliferation, differentiation, and bone formation by osteoblast stimulating factor-1/pleiotrophin: osteoconductive biomimetic scaffolds for tissue engineering. J Bone Miner Res (2003) 1.14

The effect of the delivery of vascular endothelial growth factor and bone morphogenic protein-2 to osteoprogenitor cell populations on bone formation. Biomaterials (2009) 1.12

Controlled release of BMP-2 from a sintered polymer scaffold enhances bone repair in a mouse calvarial defect model. J Tissue Eng Regen Med (2012) 1.12

Tissue engineering: strategies, stem cells and scaffolds. J Anat (2008) 1.12

Applications of supercritical CO2 in the fabrication of polymer systems for drug delivery and tissue engineering. Adv Drug Deliv Rev (2007) 1.10

Dynamics of anterior-posterior axis formation in the developing mouse embryo. Nat Commun (2012) 1.08

Combination of injectable multiple growth factor-releasing scaffolds and cell therapy as an advanced modality to enhance tissue neovascularization. Arterioscler Thromb Vasc Biol (2010) 1.07

Promotion of human dermal fibroblast migration, matrix remodelling and modification of fibroblast morphology within a novel 3D model by Lucilia sericata larval secretions. J Invest Dermatol (2006) 1.07

Attachment of stem cells to scaffold particles for intra-cerebral transplantation. Nat Protoc (2009) 1.04

Mathematical modelling of engineered tissue growth using a multiphase porous flow mixture theory. J Math Biol (2006) 1.02

Adenoviral BMP-2 gene transfer in mesenchymal stem cells: in vitro and in vivo bone formation on biodegradable polymer scaffolds. Biochem Biophys Res Commun (2002) 0.99

Chemical modification of mammalian cell surfaces. Chem Soc Rev (2003) 0.98

Differentiation of osteoblasts from murine embryonic stem cells by overexpression of the transcriptional factor osterix. Tissue Eng (2004) 0.97

Directed differentiation of human embryonic stem cells to interrogate the cardiac gene regulatory network. Mol Ther (2011) 0.97

Cigarette smoke decreases inducible nitric oxide synthase in lung epithelial cells. Exp Lung Res (2003) 0.97

The effect of delivery via narrow-bore needles on mesenchymal cells. Regen Med (2009) 0.96

Neo-vascularization of the stroke cavity by implantation of human neural stem cells on VEGF-releasing PLGA microparticles. Biomaterials (2012) 0.96

Human osteoprogenitor bone formation using encapsulated bone morphogenetic protein 2 in porous polymer scaffolds. Tissue Eng (2004) 0.96

Plasticization and spraying of poly (DL-lactic acid) using supercritical carbon dioxide: control of particle size. J Pharm Sci (2004) 0.96

The effect of mesenchymal populations and vascular endothelial growth factor delivered from biodegradable polymer scaffolds on bone formation. Biomaterials (2008) 0.95

Maggots and wound healing: an investigation of the effects of secretions from Lucilia sericata larvae upon the migration of human dermal fibroblasts over a fibronectin-coated surface. Wound Repair Regen (2005) 0.95

In vitro assessment of cell penetration into porous hydroxyapatite scaffolds with a central aligned channel. Biomaterials (2004) 0.95

Immunoselection and adenoviral genetic modulation of human osteoprogenitors: in vivo bone formation on PLA scaffold. Biochem Biophys Res Commun (2002) 0.95

Autonomic nerve trauma at radical hysterectomy: the nerve content and subtypes within the superficial and deep uterosacral ligaments. Reprod Sci (2008) 0.94

Pelvic nerve plexus trauma at radical and simple hysterectomy: a quantitative study of nerve types in the uterine supporting ligaments. J Soc Gynecol Investig (2002) 0.93

Scaffolds for liver tissue engineering. Expert Rev Med Devices (2006) 0.92

A novel technique for the production of electrospun scaffolds with tailored three-dimensional micro-patterns employing additive manufacturing. Biofabrication (2014) 0.91

Supercritical carbon dioxide: putting the fizz into biomaterials. Philos Trans A Math Phys Eng Sci (2006) 0.91

Control of pore size and structure of tissue engineering scaffolds produced by supercritical fluid processing. Eur Cell Mater (2007) 0.91

Scaffolds containing growth factors and extracellular matrix induce hepatocyte proliferation and cell migration in normal and regenerating rat liver. J Hepatol (2010) 0.90

The effect of processing variables on morphological and mechanical properties of supercritical CO2 foamed scaffolds for tissue engineering. Acta Biomater (2011) 0.90

The effect of three-dimensional co-culture of hepatocytes and hepatic stellate cells on key hepatocyte functions in vitro. Cells Tissues Organs (2005) 0.90

The production of protein-loaded microparticles by supercritical fluid enhanced mixing and spraying. J Control Release (2005) 0.90

Characterization of human fetal osteoblasts by microarray analysis following stimulation with 58S bioactive gel-glass ionic dissolution products. J Biomed Mater Res B Appl Biomater (2006) 0.89

Three-Dimensional Bioactive and Biodegradable Scaffolds Fabricated by Surface-Selective Laser Sintering. Adv Mater (2004) 0.89

Reconstruction of spatially orientated myotubes in vitro using electrospun, parallel microfibre arrays. Eur Cell Mater (2007) 0.88

Biocompatibility and osteogenic potential of human fetal femur-derived cells on surface selective laser sintered scaffolds. Acta Biomater (2009) 0.88

Laminin and fibronectin treatment leads to generation of dendritic cells with superior endocytic capacity. PLoS One (2010) 0.88

Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation. Proc Natl Acad Sci U S A (2014) 0.88

PLGA/PEG-hydrogel composite scaffolds with controllable mechanical properties. J Biomed Mater Res B Appl Biomater (2013) 0.87

Engineering embryonic stem-cell aggregation allows an enhanced osteogenic differentiation in vitro. Tissue Eng Part C Methods (2010) 0.86

Gene therapy used for tissue engineering applications. J Pharm Pharmacol (2007) 0.86

Controlled embryoid body formation via surface modification and avidin-biotin cross-linking. Cytotechnology (2010) 0.86

Dose- and time-dependent effect of bioactive gel-glass ionic-dissolution products on human fetal osteoblast-specific gene expression. J Biomed Mater Res B Appl Biomater (2005) 0.85

A thermoreversible hydrogel as a biosynthetic bandage for corneal wound repair. Biomaterials (2007) 0.85

Clinical applications of musculoskeletal tissue engineering. Br Med Bull (2008) 0.85

Aggregation promotes cell viability, proliferation, and differentiation in an in vitro model of injection cell therapy. J Tissue Eng Regen Med (2011) 0.84

Mammalian cell survival and processing in supercritical CO(2). Proc Natl Acad Sci U S A (2006) 0.84

Rapid micropatterning of cell lines and human pluripotent stem cells on elastomeric membranes. Biotechnol Bioeng (2012) 0.83

Zonal release of proteins within tissue engineering scaffolds. J Mater Sci Mater Med (2006) 0.83

Accelerated formation of multicellular 3-D structures by cell-to-cell cross-linking. Biotechnol Bioeng (2007) 0.83

Development of a slow non-viral DNA release system from PDLLA scaffolds fabricated using a supercritical CO2 technique. Biotechnol Bioeng (2007) 0.83

Alpha-MSH inhibits inflammatory signalling in Schwann cells. Neuroreport (2004) 0.82

Adjuvant chemotherapy for brain tumors delivered via a novel intra-cavity moldable polymer matrix. PLoS One (2013) 0.81

Label-free molecular imaging of immunological synapses between dendritic and T cells by Raman micro-spectroscopy. Analyst (2010) 0.81

Embryonic stem cells. J Pathol (2002) 0.81

Accelerating protein release from microparticles for regenerative medicine applications. Mater Sci Eng C Mater Biol Appl (2013) 0.81

The biology of equine mesenchymal stem cells: phenotypic characterization, cell surface markers and multilineage differentiation. Front Biosci (Landmark Ed) (2012) 0.81

Cell-type-specific adhesion onto polymer surfaces from mixed cell populations. Biotechnol Bioeng (2003) 0.80

Thermally triggered assembly of cationic graft copolymers containing 2-(2-methoxyethoxy)ethyl methacrylate side chains. Langmuir (2011) 0.80

The Intercostal NMJ Assay: a new alternative to the conventional LD50 assay for the determination of the therapeutic potency of botulinum toxin preparations. Altern Lab Anim (2008) 0.79

Spatial confinement of neurite regrowth from dorsal root ganglia within nonporous microconduits. Tissue Eng (2003) 0.79

Encapsulation of RIN-m5F cells within Ba2+ cross-linked alginate beads affects proliferation and insulin secretion. J Microencapsul (2006) 0.78

The application of human bone marrow stromal cells and poly(dl-lactic acid) as a biological bone graft extender in impaction bone grafting. Biomaterials (2008) 0.78

Biocompatibility and enhanced osteogenic differentiation of human mesenchymal stem cells in response to surface engineered poly(D,L-lactic-co-glycolic acid) microparticles. J Biomed Mater Res A (2013) 0.78

Gelation of microsphere dispersions using a thermally-responsive graft polymer. J Colloid Interface Sci (2013) 0.78

An automated fabrication strategy to create patterned tubular architectures at cell and tissue scales. Biofabrication (2015) 0.78

In situ gelling hydrogels incorporating microparticles as drug delivery carriers for regenerative medicine. J Pharm Sci (2008) 0.78

The scale-up of a tissue engineered porous hydroxyapatite polymer composite scaffold for use in bone repair: an ovine femoral condyle defect study. J Biomed Mater Res A (2014) 0.78

Uniform cell colonization of porous 3-D scaffolds achieved using radial control of surface chemistry. Acta Biomater (2011) 0.77

Ultrasonic monitoring of foamed polymeric tissue scaffold fabrication. J Mater Sci Mater Med (2008) 0.77

Development of a porous poly(DL-lactic acid-co-glycolic acid)-based scaffold for mastoid air-cell regeneration. Laryngoscope (2013) 0.77

Thermoresponsive and photocrosslinkable PEGMEMA-PPGMA-EGDMA copolymers from a one-step ATRP synthesis. Biomacromolecules (2009) 0.77

Development of a bioluminescent ATP assay to quantify mammalian and bacterial cell number from a mixed population. Biomaterials (2003) 0.77

Image-based characterization of foamed polymeric tissue scaffolds. Biomed Mater (2008) 0.77

The effect of injection using narrow-bore needles on mammalian cells: administration and formulation considerations for cell therapies. J Pharm Pharmacol (2015) 0.77

Novel surface entrapment process for the incorporation of bioactive molecules within preformed alginate fibers. Biomacromolecules (2005) 0.77

Controlling protein release from scaffolds using polymer blends and composites. Eur J Pharm Biopharm (2007) 0.76

Interconnectivity analysis of supercritical CO₂-foamed scaffolds. Comput Methods Programs Biomed (2010) 0.76

Scaffold for tissue engineering fabricated by non-isothermal supercritical carbon dioxide foaming of a highly crystalline polyester. Acta Biomater (2009) 0.76

Alpha-MSH inhibits inflammatory signalling in olfactory ensheathing cells. Neuroreport (2003) 0.76

A thermoresponsive and magnetic colloid for 3D cell expansion and reconfiguration. Adv Mater (2014) 0.76

Synthesis and characterization of novel poly[(organo)phosphazenes] with cell-adhesive side groups. Biomacromolecules (2007) 0.75

The visualisation of vitreous using surface modified poly(lactic-co-glycolic acid) microparticles. Br J Ophthalmol (2010) 0.75

Investigation of localized delivery of diclofenac sodium from poly(D,L-lactic acid-co-glycolic acid)/poly(ethylene glycol) scaffolds using an in vitro osteoblast inflammation model. Tissue Eng Part A (2014) 0.75

Hollow colloidosomes prepared using accelerated solvent evaporation. Langmuir (2013) 0.75

Photo-cross-linked hydrogels from thermoresponsive PEGMEMA-PPGMA-EGDMA copolymers containing multiple methacrylate groups: mechanical property, swelling, protein release, and cytotoxicity. Biomacromolecules (2009) 0.75

Neuralization of mouse embryonic stem cells in alginate hydrogels under retinoic acid and SAG treatment. Conf Proc IEEE Eng Med Biol Soc (2015) 0.75

Incorporation of proteins within alginate fibre-based scaffolds using a post-fabrication entrapment method. J Pharm Pharmacol (2006) 0.75

Early gene regulation of osteogenesis in embryonic stem cells. Integr Biol (Camb) (2012) 0.75

Time-lapsed imaging for in-process evaluation of supercritical fluid processing of tissue engineering scaffolds. Biotechnol Prog (2009) 0.75

Engineering an in-vitro model of rodent cartilage. J Pharm Pharmacol (2012) 0.75