Published in Blood on March 27, 2013
HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells. Elife (2015) 0.84
Complement opsonization of HIV-1 results in decreased antiviral and inflammatory responses in immature dendritic cells via CR3. J Immunol (2014) 0.84
HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells. Retrovirology (2014) 0.79
Cognitive consequences of a sustained monocyte type 1 IFN response in HIV-1 infection. Curr HIV Res (2014) 0.76
Tat is a multifunctional viral protein that modulates cellular gene expression and functions. Oncotarget (2017) 0.75
MicroRNA-541 promotes the proliferation of vascular smooth muscle cells by targeting IRF7. Am J Transl Res (2016) 0.75
Effect of combination therapy of propofol and sevoflurane on MAP2K3 level and myocardial apoptosis induced by ischemia-reperfusion in rats. Int J Clin Exp Med (2015) 0.75
Mechanism of Interferon Stimulated Gene Induction in HIV-1 Infected Macrophages. J Virol (2017) 0.75
Mammalian MAP kinase signalling cascades. Nature (2001) 18.89
Toll-like receptors and innate immunity. Nat Rev Immunol (2001) 16.50
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science (2002) 14.50
Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat Rev Immunol (2005) 11.57
IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat Rev Immunol (2006) 7.98
MAP kinases in the immune response. Annu Rev Immunol (2001) 7.62
Chromatin immunoprecipitation and microarray-based analysis of protein location. Nat Protoc (2006) 7.29
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol Cell Biol (1996) 6.91
Regulation of JAK-STAT signalling in the immune system. Nat Rev Immunol (2003) 5.77
Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli. J Virol (1996) 5.71
Activation and signaling of the p38 MAP kinase pathway. Cell Res (2005) 5.48
Mutational analysis of the conserved basic domain of human immunodeficiency virus tat protein. J Virol (1989) 2.89
HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. Nat Med (2003) 2.62
The multi-tasking P-TEFb complex. Curr Opin Cell Biol (2008) 2.53
Role of STAT2 in the alpha interferon signaling pathway. Mol Cell Biol (1995) 2.34
Genetic variation in Toll-like receptors and disease susceptibility. Nat Immunol (2012) 2.09
p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons. EMBO J (1999) 2.07
The control of HIV transcription: keeping RNA polymerase II on track. Cell Host Microbe (2011) 2.05
Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription. Nucleic Acids Res (2007) 2.02
IRF7: activation, regulation, modification and function. Genes Immun (2011) 1.80
Activation of host pattern recognition receptors by viruses. Curr Opin Microbiol (2010) 1.73
Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster. EMBO J (1995) 1.61
The Rac1/p38 mitogen-activated protein kinase pathway is required for interferon alpha-dependent transcriptional activation but not serine phosphorylation of Stat proteins. J Biol Chem (2000) 1.47
Regulation of the transcriptional activity of the IRF7 promoter by a pathway independent of interferon signaling. J Biol Chem (2005) 1.45
Differentiation of monocytes to macrophages primes cells for lipopolysaccharide stimulation via accumulation of cytoplasmic nuclear factor kappaB. Infect Immun (1999) 1.43
Interferon-alpha drives monocyte gene expression in chronic unsuppressed HIV-1 infection. AIDS (2010) 1.34
Transcription factor redundancy ensures induction of the antiviral state. J Biol Chem (2010) 1.32
Induction of the chemokines interleukin-8 and IP-10 by human immunodeficiency virus type 1 tat in astrocytes. J Virol (2000) 1.32
p38 MAPK enhances STAT1-dependent transcription independently of Ser-727 phosphorylation. Proc Natl Acad Sci U S A (2002) 1.30
Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation. Nat Immunol (2012) 1.28
HIV-1 activates macrophages independent of Toll-like receptors. PLoS One (2008) 1.26
TLR7 stimulation in human plasmacytoid dendritic cells leads to the induction of early IFN-inducible genes in the absence of type I IFN. Blood (2009) 1.20
Interferon gene expression following HIV type 1 infection of monocyte-derived macrophages. AIDS Res Hum Retroviruses (2004) 1.13
Alternative and accessory pathways in the regulation of IFN-beta-mediated gene expression. J Interferon Cytokine Res (2005) 1.11
Evidence for distinct intracellular signaling pathways in CD34+ progenitor to dendritic cell differentiation from a human cell line model. J Immunol (1999) 1.09
Proinflammatory cytokines and HIV-1 synergistically enhance CXCL10 expression in human astrocytes. Glia (2009) 1.08
New insights into the control of HIV-1 transcription: when Tat meets the 7SK snRNP and super elongation complex (SEC). J Neuroimmune Pharmacol (2011) 1.06
Type I interferon during viral infections: multiple triggers for a multifunctional mediator. Curr Top Microbiol Immunol (2007) 1.06
Signaling through the P38 and ERK pathways: a common link between HIV replication and the immune response. Immunol Res (2010) 1.04
Dysregulation of mitogen-activated protein kinase signaling pathways in simian immunodeficiency virus encephalitis. Am J Pathol (2004) 1.04
Inhibition of mixed lineage kinase 3 prevents HIV-1 Tat-mediated neurotoxicity and monocyte activation. J Immunol (2006) 1.02
HIV-1 Tat co-operates with IFN-gamma and TNF-alpha to increase CXCL10 in human astrocytes. PLoS One (2009) 1.00
Tat-induced FOXO3a is a key mediator of apoptosis in HIV-1-infected human CD4+ T lymphocytes. J Immunol (2008) 1.00
Association of Tat with promoters of PTEN and PP2A subunits is key to transcriptional activation of apoptotic pathways in HIV-infected CD4+ T cells. PLoS Pathog (2010) 0.99
A peripheral monocyte interferon phenotype in HIV infection correlates with a decrease in magnetic resonance spectroscopy metabolite concentrations. AIDS (2011) 0.89
Impact of Tat Genetic Variation on HIV-1 Disease. Adv Virol (2012) 0.85
Activation of mitogen-activated protein kinase kinase (MKK) 3 and MKK6 by type I interferons. J Biol Chem (2005) 0.85
An overview of intracellular interactions between immunodeficiency viruses and their hosts. AIDS (2012) 0.84
Cell-type-specific proteome and interactome: using HIV-1 Tat as a test case. Expert Rev Proteomics (2009) 0.80
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell (2008) 16.38
Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells. Proc Natl Acad Sci U S A (2013) 2.75
HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. Nat Med (2003) 2.62
Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure. Circ Res (2009) 2.44
LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker. Nat Med (2012) 2.24
Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation. Mol Cell (2008) 1.93
HIF1alpha synergizes with glucocorticoids to promote BFU-E progenitor self-renewal. Blood (2010) 1.63
Control of simian/human immunodeficiency virus viremia and disease progression after IL-2-augmented DNA-modified vaccinia virus Ankara nasal vaccination in nonhuman primates. J Immunol (2004) 1.28
RNA incorporation is critical for retroviral particle integrity after cell membrane assembly of Gag complexes. J Virol (2002) 1.21
Pathway of care among psychiatric patients attending a mental health institution in central India. Indian J Psychiatry (2010) 1.08
Nucleocapsid-RNA interactions are essential to structural stability but not to assembly of retroviruses. J Virol (2004) 1.05
Tat-induced FOXO3a is a key mediator of apoptosis in HIV-1-infected human CD4+ T lymphocytes. J Immunol (2008) 1.00
Association of Tat with promoters of PTEN and PP2A subunits is key to transcriptional activation of apoptotic pathways in HIV-infected CD4+ T cells. PLoS Pathog (2010) 0.99
Tula hantavirus infection of Vero E6 cells induces apoptosis involving caspase 8 activation. J Gen Virol (2004) 0.99
Genomic profiling of atypical meningiomas associates gain of 1q with poor clinical outcome. J Neuropathol Exp Neurol (2009) 0.97
Genome-wide analyses of Nkx2-1 binding to transcriptional target genes uncover novel regulatory patterns conserved in lung development and tumors. PLoS One (2012) 0.93
An SHIV DNA/MVA rectal vaccination in macaques provides systemic and mucosal virus-specific responses and protection against AIDS. AIDS Res Hum Retroviruses (2004) 0.92
Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome. PLoS One (2012) 0.91
DNA-MVA vaccine protection after X4 SHIV challenge in macaques correlates with day-of-challenge antiviral CD4+ cell-mediated immunity levels and postchallenge preservation of CD4+ T cell memory. AIDS Res Hum Retroviruses (2008) 0.90
Agomelatine versus other antidepressive agents for major depression. Cochrane Database Syst Rev (2013) 0.89
The simian immunodeficiency virus 5' untranslated leader sequence plays a role in intracellular viral protein accumulation and in RNA packaging. J Virol (2003) 0.89
HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells. Retrovirology (2014) 0.79
Assessment of pharmacokinetic interaction of spirulina with glitazone in a type 2 diabetes rat model. J Med Food (2013) 0.77
Whole-body MRI of juvenile spondyloarthritis: protocols and pictorial review of characteristic patterns. Pediatr Radiol (2015) 0.77
Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants. Virology (2002) 0.77
Functional analysis of the murine sarcoma virus RNA packaging sequence. J Virol (2002) 0.77
Comparison of respiratory-triggered 3-D fast spin-echo and single-shot fast spin-echo radial slab MR cholangiopancreatography images in children. Pediatr Radiol (2013) 0.77
Boundary conditions by Schwarz-Christoffel mapping in anatomically accurate hemodynamics. Ann Biomed Eng (2008) 0.77
Agomelatine - is it another reboxetine? Another case of publication bias. Psychiatr Bull (2014) (2014) 0.75
Group-based psychosocial intervention for bipolar disorder. Br J Psychiatry (2010) 0.75
Unsung hero Robert C. Gallo. Science (2009) 0.75
Acute and chronic inflammation studies of Strobilanthes callosus leaves extract on rat model. Inflammopharmacology (2012) 0.75