|
1
|
Structural basis of ubiquitin recognition by the deubiquitinating protease USP2.
|
Structure
|
2006
|
1.92
|
|
2
|
Biochemical characterization of USP7 reveals post-translational modification sites and structural requirements for substrate processing and subcellular localization.
|
FEBS J
|
2007
|
1.14
|
|
3
|
Aspartic proteases in drug discovery.
|
Curr Pharm Des
|
2007
|
1.12
|
|
4
|
Modulation of inositol 1,4,5-triphosphate concentration by prolyl endopeptidase inhibition.
|
Eur J Biochem
|
2002
|
1.00
|
|
5
|
Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion.
|
J Neurochem
|
2005
|
0.94
|
|
6
|
Synthesis and characterization of fluorescent ubiquitin derivatives as highly sensitive substrates for the deubiquitinating enzymes UCH-L3 and USP-2.
|
Anal Biochem
|
2005
|
0.89
|
|
7
|
Inhibition of mammalian legumain by Michael acceptors and AzaAsn-halomethylketones.
|
Biol Chem
|
2002
|
0.87
|
|
8
|
A quantitative homogeneous assay for fragile X mental retardation 1 protein.
|
J Neurodev Disord
|
2013
|
0.85
|
|
9
|
Crystal structure of an activation intermediate of cathepsin E.
|
J Mol Biol
|
2004
|
0.83
|
|
10
|
A novel class of oral direct renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore.
|
J Med Chem
|
2013
|
0.83
|
|
11
|
Characterisation of human dipeptidyl peptidase IV expressed in Pichia pastoris. A structural and mechanistic comparison between the recombinant human and the purified porcine enzyme.
|
Biol Chem
|
2003
|
0.82
|
|
12
|
Crystal structure of human BACE2 in complex with a hydroxyethylamine transition-state inhibitor.
|
J Mol Biol
|
2005
|
0.81
|
|
13
|
Backbone 1H, 13C, and 15N resonance assignments for the 26-kD human de-ubiquitinating enzyme UCH-L3.
|
Biomol NMR Assign
|
2007
|
0.78
|
|
14
|
Highly sensitive intramolecularly quenched fluorogenic substrates for renin based on the combination of L-2-amino-3-(7-methoxy-4-coumaryl)propionic acid with 2,4-dinitrophenyl groups at various positions.
|
Biochem J
|
2004
|
0.77
|
|
15
|
Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes.
|
Bioorg Med Chem Lett
|
2011
|
0.76
|
|
16
|
Characterisation of human DP IV produced by a Pichia pastoris expression system.
|
Adv Exp Med Biol
|
2003
|
0.75
|
|
17
|
Acylated hydroxamates as selective and highly potent inhibitors of dipeptidyl peptidase I.
|
Adv Exp Med Biol
|
2003
|
0.75
|