PubRank

H Kalthoff

Author PubWeight™ 95.14‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4. Virchows Arch 2001 2.73
2 Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis. J Cell Biol 2004 2.70
3 Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the beta4 integrin and the PI3k pathway. Oncogene 2006 2.36
4 Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction. J Clin Oncol 1994 1.78
5 Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis. Oncogene 2000 1.69
6 Immunochemical characterization and quantitative distribution of pancreatic stone protein in sera and pancreatic secretions in pancreatic disorders. Gastroenterology 1990 1.60
7 Loss of sst2 somatostatin receptor gene expression in human pancreatic and colorectal cancer. Cancer Res 1996 1.59
8 DNA repair and recombination factor Rad51 is over-expressed in human pancreatic adenocarcinoma. Oncogene 2000 1.56
9 TRAIL promotes metastasis of human pancreatic ductal adenocarcinoma. Oncogene 2006 1.55
10 Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin. Oncogene 2001 1.46
11 Systemic and local immunosuppression in pancreatic cancer patients. Clin Cancer Res 2001 1.44
12 Immunocytological detection of micrometastatic cells: comparative evaluation of findings in the peritoneal cavity and the bone marrow of gastric, colorectal and pancreatic cancer patients. Int J Cancer 1994 1.39
13 Comparative analysis of bone marrow and venous blood isolates from gastrointestinal cancer patients for the detection of disseminated tumor cells using reverse transcription PCR. Cancer Res 1997 1.36
14 Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2). Oncogene 2009 1.32
15 Lysis of a broad range of epithelial tumour cells by human gamma delta T cells: involvement of NKG2D ligands and T-cell receptor- versus NKG2D-dependent recognition. Scand J Immunol 2007 1.32
16 Human pancreatic adenocarcinomas express Fas and Fas ligand yet are resistant to Fas-mediated apoptosis. Cancer Res 1998 1.28
17 Immunohistochemical screening for beta6-integrin subunit expression in adenocarcinomas using a novel monoclonal antibody reveals strong up-regulation in pancreatic ductal adenocarcinomas in vivo and in vitro. Histopathology 2004 1.28
18 Multiple and synergistic deregulations of apoptosis-controlling genes in pancreatic carcinoma cells. Br J Cancer 2003 1.24
19 The detection of disseminated tumor cells in bone marrow from colorectal-cancer patients by a cytokeratin-20-specific nested reverse-transcriptase-polymerase-chain reaction is related to the stage of disease. Int J Cancer 1996 1.21
20 Tumor necrosis factor alpha induces the expression of transforming growth factor alpha and the epidermal growth factor receptor in human pancreatic cancer cells. Proc Natl Acad Sci U S A 1993 1.20
21 Lovastatin inhibits proliferation of pancreatic cancer cell lines with mutant as well as with wild-type K-ras oncogene but has different effects on protein phosphorylation and induction of apoptosis. Int J Oncol 1998 1.18
22 Anti-apoptotic and growth-stimulatory functions of CK1 delta and epsilon in ductal adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in vivo. Gut 2008 1.15
23 DPC4/SMAD4 mediated tumor suppression of colon carcinoma cells is associated with reduced urokinase expression. Oncogene 1999 1.13
24 ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma. Br J Cancer 2004 1.11
25 CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells. Oncogene 2001 1.10
26 FAP-1 in pancreatic cancer cells: functional and mechanistic studies on its inhibitory role in CD95-mediated apoptosis. J Cell Sci 2001 1.10
27 TLR-3 polymorphism is an independent prognostic marker for stage II colorectal cancer. Eur J Cancer 2011 1.07
28 Frequent codeletion of p16/MTS1 and p15/MTS2 and genetic alterations in p16/MTS1 in pancreatic tumors. Gastroenterology 1996 1.05
29 Isolated tumor cells are frequently detectable in the peritoneal cavity of gastric and colorectal cancer patients and serve as a new prognostic marker. Ann Surg 1998 1.04
30 In vivo studies on the incorporation of microinjected acidic proteins of the large ribosomal subunit from Escherichia coli and artermia salina into oocyte ribosomes from Xenopus laevis. Biochemistry 1979 1.00
31 Dissecting the role of TGF-beta type I receptor/ALK5 in pancreatic ductal adenocarcinoma: Smad activation is crucial for both the tumor suppressive and prometastatic function. Oncogene 2007 0.99
32 Monoclonal antibody defines CA 19-9 in pancreatic juices and sera. Gut 1985 0.98
33 Disseminated tumour cells. Their detection and significance for prognosis of gastrointestinal and pancreatic carcinomas. Virchows Arch 2001 0.96
34 Characterization of CA 19-9 bearing mucins as physiological exocrine pancreatic secretion products. Cancer Res 1986 0.96
35 Autocrine stimulation of human pancreatic duct-like development by soluble isoforms of epimorphin in vitro. J Cell Biol 2001 0.96
36 Mutant PIK3CA licenses TRAIL and CD95L to induce non-apoptotic caspase-8-mediated ROCK activation. Cell Death Differ 2010 0.95
37 Autoantibodies in sera of pancreatic cancer patients identify recombination factor Rad51 as a tumour-associated antigen. J Cancer Res Clin Oncol 2002 0.94
38 Antiproliferative effects exerted by recombinant human tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) on human pancreatic tumor cell lines. Pancreas 1988 0.93
39 Complementary effects of HDAC inhibitor 4-PB on gap junction communication and cellular export mechanisms support restoration of chemosensitivity of PDAC cells. Br J Cancer 2006 0.93
40 Disseminated tumor cells in pancreatic cancer patients detected by immunocytology: a new prognostic factor. Clin Cancer Res 1999 0.93
41 Combretastatin A-4 prodrug inhibits growth of human non-small cell lung cancer in a murine xenotransplant model. Ann Thorac Surg 2001 0.92
42 Orthotopic transplantation model of human gastrointestinal cancer and detection of micrometastases. World J Gastroenterol 2001 0.92
43 A tumor-selective somatostatin analog (TT-232) with strong in vitro and in vivo antitumor activity. Proc Natl Acad Sci U S A 1996 0.91
44 Overexpression of p53 protein during pancreatitis. Br J Cancer 1997 0.91
45 Monoclonal antibody-defined human pancreatic cancer-associated antigens. Cancer Res 1985 0.90
46 Human endostatin inhibits growth of human non-small-cell lung cancer in a murine xenotransplant model. Int J Cancer 2001 0.88
47 Ribosomal protein S6 from Xenopus laevis ovaries. Isolation, phosphorylation in vivo and cross-reaction with heterologous anti-S6 antibodies. Eur J Biochem 1982 0.88
48 Intact tissue of gastrointestinal cancer specimen orthotopically transplanted into nude mice. Hepatogastroenterology 1999 0.88
49 The TNF family member APRIL promotes colorectal tumorigenesis. Cell Death Differ 2012 0.88
50 DU-PAN-2 levels in serum and pancreatic ductal fluids of patients with benign and malignant pancreatic disease. Pancreas 1988 0.87
51 Frequent expression of complement resistance factors CD46, CD55, and CD59 on gastrointestinal cancer cells limits the therapeutic potential of monoclonal antibody 17-1A. J Surg Oncol 1997 0.87
52 Transcription of cloned Moloney murine leukemia proviral DNA injected into Xenopus laevis oocytes. Nucleic Acids Res 1983 0.87
53 The phosphorylation of ribosomal protein S6 from progesterone-stimulated Xenopus laevis oocytes. Kinetic studies and phosphopeptide analysis. Eur J Biochem 1983 0.87
54 Co-expression of KLK6 and KLK10 as prognostic factors for survival in pancreatic ductal adenocarcinoma. Br J Cancer 2008 0.86
55 Differential mucin MUC7 gene expression in invasive bladder carcinoma in contrast to uniform MUC1 and MUC2 gene expression in both normal urothelium and bladder carcinoma. Cancer Res 1998 0.86
56 Immunological escape mechanisms in pancreatic carcinoma. Ann N Y Acad Sci 1999 0.86
57 Combretastatin A-4 prodrug: a potent inhibitor of malignant hemangioendothelioma cell proliferation. Int J Cancer 2000 0.85
58 Molecular mechanisms of tumor metastasis and angiogenesis. Langenbecks Arch Surg 1999 0.84
59 Dipeptidase 1 (DPEP1) is a marker for the transition from low-grade to high-grade intraepithelial neoplasia and an adverse prognostic factor in colorectal cancer. Br J Cancer 2013 0.84
60 Regulation of T-cell death-associated gene 51 (TDAG51) expression in human T-cells. Cell Death Differ 2004 0.84
61 TGFbeta-induced growth inhibition involves cell cycle inhibitor p21 and pRb independent from p15 expression. Int J Oncol 1999 0.84
62 Hollow-spheres: a new model for analyses of differentiation of pancreatic duct epithelial cells. Ann N Y Acad Sci 1999 0.83
63 Subcellular transport and ribosomal incorporation of microinjected protein S6 in oocytes from Xenopus laevis. Biochemistry 1982 0.83
64 Cytokeratin-20 reverse-transcriptase polymerase chain reaction as a new tool for the detection of circulating tumor cells in peripheral blood and bone marrow of bladder cancer patients. Eur Urol 2001 0.83
65 Prognostic relevance of C-terminal Mdm2 detection is enhanced by p53 positivity in soft tissue sarcomas. Diagn Mol Pathol 1997 0.82
66 An improved orthotopic xenotransplant procedure for human lung cancer in SCID bg mice. Ann Thorac Surg 2000 0.82
67 Detection of the anti-p53 antibody response in malignant and benign pancreatic disease. Br J Cancer 1994 0.82
68 [Intraocular pressure in snorkling and diving (author's transl)]. Klin Monbl Augenheilkd 1976 0.82
69 Apoptosis by gemcitabine in non-small cell lung cancer cell line KNS62 is induced downstream of caspase 8 and is profoundly blocked by Bcl-xL over-expression. Langenbecks Arch Surg 2005 0.82
70 Biglycan gene expression in the human leiomyosarcoma cell line SK-UT-1. Basal and protein kinase A-induced transcription involves binding of Sp1-like/Sp3 proteins in the proximal promoter region. J Biol Chem 1998 0.81
71 Transduction of human pancreatic tumor cells with vesicular stomatitis virus G-pseudotyped retroviral vectors containing a herpes simplex virus thymidine kinase mutant gene enhances bystander effects and sensitivity to ganciclovir. Cancer Gene Ther 2000 0.81
72 Subcellular distribution of ribosomal proteins S6 and eL12. Analysis by autoradiography and immunofluorescence of sections from oocytes of Xenopus laevis. Cell Tissue Res 1984 0.81
73 Clinical relevance of pRb and p53 co-overexpression in soft tissue sarcomas. Cancer Lett 1999 0.81
74 The 'N-factors' in pancreatic cancer: functional relevance of NF-κB, NFAT and Nrf2 in pancreatic cancer. Oncogenesis 2012 0.80
75 A human carcinoma model in athymic rats reflecting solid and disseminated colorectal metastases. Langenbecks Arch Surg 1998 0.80
76 Cytokine-mediated enhancement of epidermal growth factor receptor expression provides an immunological approach to the therapy of pancreatic cancer. Proc Natl Acad Sci U S A 1997 0.80
77 Monoclonal antibodies for characterization of the heterogeneity of normal and malignant transitional cells. J Urol 1987 0.80
78 Prognostic value of immunohistochemistry for p53 in primary soft-tissue sarcomas: a multivariate analysis of five antibodies. J Cancer Res Clin Oncol 1997 0.80
79 Dynamics of antibody transport and internalization. Int J Cancer Suppl 1988 0.80
80 High prognostic significance of Mdm2/p53 co-overexpression in soft tissue sarcomas of the extremities. Oncogene 1998 0.79
81 Pancreatic stone protein in serum of patients with pancreatitis. Lancet 1986 0.78
82 [Problems of intraocular pressure in scuba diving (author's transl)]. Klin Monbl Augenheilkd 1975 0.78
83 A bifunctional HBED-derivative for labeling of antibodies with 67Ga, 111In and 59Fe. Comparative biodistribution with 111In-DPTA and 131I-labeled antibodies in mice bearing antibody internalizing and non-internalizing tumors. Int J Rad Appl Instrum B 1992 0.78
84 Multiparametric tumor marker (CA 19-9, CEA, AFP, POA) analyses of pancreatic juices and sera in pancreatic diseases. Hepatogastroenterology 1985 0.78
85 Biglycan gene promoter activity in osteosarcoma cells is regulated by cyclic AMP. Biochem Biophys Res Commun 1997 0.77
86 [CD95 resistance and Fas ligand synthesis as mechanism of defense by immunocompetent cells in pancreatic tumors]. Langenbecks Arch Chir Suppl Kongressbd 1998 0.77
87 [Immunocytologic detection of disseminated tumor cells in the peritoneal cavity and bone marrow in patients with pancreatic carcinoma]. Chirurg 1994 0.77
88 Enzymatic degradation of various antisense oligonucleotides: monitoring and fragment identification by MECC and ES-MS. Biomed Pept Proteins Nucleic Acids 1995 0.77
89 Antibody transport and internalization into tumours. Br J Cancer Suppl 1990 0.76
90 [Comparative study of metastasis-associated characteristics of tumor cells with different metastatic capacities]. Zhonghua Zhong Liu Za Zhi 2000 0.76
91 Accumulation characteristics of human colon carcinomas after monoclonal antibody ex vivo perfusion. Br J Cancer Suppl 1990 0.75
92 A monoclonal antibody-cobra venom factor conjugate increases the tumor-specific uptake of a 99mTc-labeled anti-carcinoembryonic antigen antibody by a two-step approach. Cancer Res 1995 0.75
93 Human pancreatic cancer cell lines express the CCKB receptor. Hepatogastroenterology 1999 0.75
94 The role of cytokines in pancreatic cancer. Int J Pancreatol 1996 0.75
95 Irrigation and aspiration of congenital and soft cataracts by the Fuchs' two-way syringe. Ann Ophthalmol 1971 0.75
96 ELISA-based Ki-ras gene mutation analyses in pancreatic and cholangiocarcinoma cells and tissues. Oncol Rep 2001 0.75
97 [Interaction of gastrointestinal receptor tyrosine kinases with cytokines exemplified by pancreatic cancer]. Z Gastroenterol Verh 1991 0.75
98 Detachment of cell surface-bound anticarcinoembryonic antigen immune complexes by phospholipase C. Tumour Biol 1991 0.75
99 [The Tumor Immunology Study Group: tumor immunology of the gastrointestinal tract--experimental and clinical experiences]. Z Gastroenterol Verh 1988 0.75
100 Ablation of tumor cells in vivo by direct injection of HSV-thymidine kinase retroviral vector and ganciclovir therapy. Ann N Y Acad Sci 1999 0.75
101 [The prone-position test in the diagnosis of narrow-angle glaucoma and the determination of its limiting value by discriminatory analysis]. Klin Monbl Augenheilkd 1971 0.75
102 [Monoclonal antibodies against tumor-associated antigens of the gastrointestinal tract. Experimental and clinical outlook]. Dtsch Med Wochenschr 1985 0.75
103 [Psychogenic amblyopia in children]. Med Monatsschr 1968 0.75
104 Enhanced retroviral transduction efficiency of pancreatic tumor cell lines using different envelope glycoproteins. Ann N Y Acad Sci 1999 0.75
105 [Infantile hysterical amblyopia--no rare disease (author's transl)]. Klin Monbl Augenheilkd 1976 0.75
106 [Mature avian eye fluke (Philophthalmus sp.) under the human conjunctiva (author's transl)]. Klin Monbl Augenheilkd 1981 0.75
107 [Characterization and induction of phenotypic differentiation markers of the pancreatico-biliary system]. Z Gastroenterol Verh 1991 0.75
108 Growth inhibition of pancreatic tumor cells by modified antisense oligodeoxynucleotides. Langenbecks Arch Surg 1998 0.75
109 [Two chains of infection of epidemic keratoconjunctivitis with different courses]. Klin Monbl Augenheilkd 1972 0.75
110 [Immunocytologic detection of micro-metastatic cells in patients with gastrointestinal tumors]. Zentralbl Chir 1995 0.75
111 Biodistribution of 131I-labelled monoclonal antibodies in human colon tumours by an ex vivo perfusion model. Int J Cancer Suppl 1988 0.75
112 Significant growth inhibition of orthotopic pancreatic ductal adenocarcinoma by CpG oligonucleotides in immunodeficient mice. Int J Colorectal Dis 2005 0.75
113 Studies on the relationship between lectins from Axinella polypoides agglutinating bacteria and human erythrocytes. J Invertebr Pathol 1978 0.75