Melanie J Scott

Author PubWeight™ 21.18‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Pivotal advance: The pattern recognition receptor ligands lipopolysaccharide and polyinosine-polycytidylic acid stimulate factor B synthesis by the macrophage through distinct but overlapping mechanisms. J Leukoc Biol 2010 1.59
2 Genetic background determines susceptibility during murine septic peritonitis. J Surg Res 2002 1.35
3 Systemic inflammation and end organ damage following trauma involves functional TLR4 signaling in both bone marrow-derived cells and parenchymal cells. J Leukoc Biol 2007 1.31
4 Hemorrhagic shock activation of NLRP3 inflammasome in lung endothelial cells. J Immunol 2011 1.25
5 Lipopolysaccharide clearance, bacterial clearance, and systemic inflammatory responses are regulated by cell type-specific functions of TLR4 during sepsis. J Immunol 2013 1.23
6 Signaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14. Mol Med 2013 1.23
7 Natural killer cells participate in bacterial clearance during septic peritonitis through interactions with macrophages. Shock 2003 1.09
8 Models of lower extremity damage in mice: time course of organ damage and immune response. J Surg Res 2010 1.04
9 Caspase 1 activation is protective against hepatocyte cell death by up-regulating beclin 1 protein and mitochondrial autophagy in the setting of redox stress. J Biol Chem 2013 1.00
10 Selective roles for toll-like receptors 2, 4, and 9 in systemic inflammation and immune dysfunction following peripheral tissue injury. J Trauma Acute Care Surg 2013 0.95
11 Caspase-1 is hepatoprotective during trauma and hemorrhagic shock by reducing liver injury and inflammation. Mol Med 2011 0.95
12 Metabolomics in pneumonia and sepsis: an analysis of the GenIMS cohort study. Intensive Care Med 2013 0.91
13 Hemorrhagic shock augments Nlrp3 inflammasome activation in the lung through impaired pyrin induction. J Immunol 2013 0.90
14 A role for cGMP in inducible nitric-oxide synthase (iNOS)-induced tumor necrosis factor (TNF) α-converting enzyme (TACE/ADAM17) activation, translocation, and TNF receptor 1 (TNFR1) shedding in hepatocytes. J Biol Chem 2012 0.89
15 Mammalian DNA is an endogenous danger signal that stimulates local synthesis and release of complement factor B. Mol Med 2012 0.84
16 TLR4 Signaling augments monocyte chemotaxis by regulating G protein-coupled receptor kinase 2 translocation. J Immunol 2013 0.84
17 Role of macrophages in mobilization of hematopoietic progenitor cells from bone marrow after hemorrhagic shock. Shock 2012 0.82
18 Trauma alters alveolar effector cell apoptosis. Surgery 2003 0.81
19 Alveolar interleukin-10 regulates neutrophil apoptosis in severely traumatized patients. J Trauma 2007 0.81
20 Laryngotracheal injuries: does injury mechanism matter? Am Surg 2004 0.79
21 A novel model of pneumonia from intraperitoneal injection of bacteria. Am J Surg 2003 0.78
22 Glutathione and thioredoxin type 1 cooperatively denitrosate HepG2 cells-derived cytosolic S-nitrosoproteins. Org Biomol Chem 2013 0.75
23 Thoracotomy for blunt trauma: traditional indications may not apply. Am Surg 2003 0.75
24 Mortality in murine peritonitis correlates with increased Escherichia coli adherence to the intestinal mucosa. Am Surg 2004 0.75